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| 1 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 2 | Redefining Budd-Chiari syndrome:A systematic review显示文摘AIM:To re-examine whether hepatic vein thrombosis(HVT)(classical Budd-Chiari syndrome)and hepatic vena cava-Budd Chiari syndrome(HVC-BCS)are the same disorder.METHODS:A systematic review of observational studies conducted in adult subjects with primary BCS,hepatic vein outflow tract obstruction,membranous obstruction of the inferior vena cava(IVC),obliterative hepatocavopathy,or HVT during the period of January2000 until February 2015 was conducted using the following databases:Cochrane Library,CINAHL,MEDLINE,Pub Med and Scopus.RESULTS:Of 1299 articles identified,26 were included in this study.Classical BCS is more common in women with a pure hepatic vein obstruction(49%-74%).HVCBCS is more common in men with the obstruction often located in both the inferior vena cava and hepatic veins(14%-84%).Classical BCS presents with acute abdominal pain,ascites,and hepatomegaly.HVC-BCS presents with chronic abdominal pain and abdominalwall varices.Myeloproliferative neoplasms(MPN)are the most common etiology of classical BCS(16%-62%)with the JAK2V617-F mutation found in 26%-52%.In HVCBCS,MPN are found in 4%-5%,and the JAK2V617-F mutation in 2%-5%.Classical BCS responds well to medical management alone and 1st line management of HVC-BCS involves percutaneous recanalization,with few managed with medical management alone.CONCLUSION:Systematic review of recent data suggests that classical BCS and HVC-BCS may be two clinically different disorders that involve the disruption of hepatic venous outflow. | Naomi Shin Young H Kim Hao Xu Hai-Bin Shi Qing-Qiao Zhang Jean Paul Colon Pons Ducksoo Kim Yi Xu Fei-Yun Wu Samuel Han Byung-Boong Lee Lin-Sun Li | 2016 | World Journal of Hepatology2016，8，16： | 6 |
| 3 | Long‐term entecavir therapy results in the reversal of fibrosis/cirrhosis and continued histological improvement in patients with chronic hepatitis B显示文摘 | Ting‐Tsung Chang Yun‐Fan Liaw Shun‐Sheng Wu Eugene Schiff Kwang‐Hyub Han Ching‐Lung Lai Rifaat Safadi Samuel S. Lee Waldemar Halota Zachary Goodman Yun‐Chan Chi Hui Zhang Robert Hindes Uchenna Iloeje Suzanne Beebe Bruce Kreter | 2010 | Hepatology2010，，： | 4 |
| 4 | Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre– and post–liver transplantation patients显示文摘 | Eugene R. Schiff Ching-Lung Lai Stefanos Hadziyannis Peter Neuhaus Norah Terrault Massimo Colombo Hans L. Tillmann Didier Samuel Stefan Zeuzem Leslie Lilly Maria Rendina Jean-Pierre Villeneuve Nicole Lama Craig James Michael S. Wulfsohn Hamid Namini Chris | 2003 | Hepatology2003，，6： | 1 |
| 5 | Optimizing the tensileproperties of Al-Si-Cu-Mg 319-type alloys: Roie of solution heattreatmcnt显示文摘 | HAN Y SAMUEL A M DOTY H W | 2014 | Materials and Design2014，58，6： | 1 |
| 6 | Statistical debugging: A hypothesis testing-based approach 显示文摘 | Chao Liu Long Fei Xifeng Yan Jiawei Han Samuel P Midldff | 2006 | IEEE Transactions on Software Engineering2006，32，10： | 1 |
| 7 | 过去10年(2007-2017年)新蚊虫相关病毒的发现和全球分布显示文摘在过去的10年里,病毒的搜寻和发现已经加快了步伐。这一成就由三个主要因素推动:(1)测序技术的进步;(2)扩大常规虫媒病毒监测策略;(3)对新出现病原体和新病毒的“搜寻”。从大量的宿主、媒介和环境样本中发现了许多新的病毒。为了有助于促进对全球蚊虫相关病毒多样性和分布的了解,并促进未来的研究,我们回顾了2007年至2017年在世界各地发现的蚊虫相关病毒。在分析期间,对属于25个家族的新发现蚊虫相关病毒和1组未分类病毒进行了分类。 | 吕新军(编译) Evans Atoni Lu Zhao Samuel Karungu Vincent Obanda Bernard Agwanda Han Xia Zhiming Yuan | 2019 | 中华实验和临床病毒学杂志2019，33，4： | 1 |
| 8 | High-purity water production with the latest modular electr-odeionization technology 显示文摘 | Philippe R Samuel A Hans A | 1997 | Ultrapure Water1997，，14： | 1 |
| 9 | Analysis of secondary source levels of a parametric array transducer显示文摘 | Samuel JH Han J Bae | | 0，，： | 1 |
| 10 | Adefovir dipivoxil therapy for lamivudine-resistant hepatitis B in pre– and post–liver transplantation patients显示文摘 | Eugene R. Schiff Ching-Lung Lai Stefanos Hadziyannis Peter Neuhaus Norah Terrault Massimo Colombo Hans L. Tillmann Didier Samuel Stefan Zeuzem Leslie Lilly Maria Rendina Jean-Pierre Villeneuve Nicole Lama Craig James Michael S. Wulfsohn Hamid Namini Chris | 2003 | Hepatology2003，，6： | 1 |
| 11 | Dissolution of AlzCu phase in non-modified and Sr modified 319 type alloys显示文摘 | HAN Y M SAMUEL A M SAMUEL F H | 2008 | International Journal of Cast Metals Research2008，21，5： | 1 |
| 12 | Optimizing the tensile pro erties of A1-Si--Cu-Mg 319-type alloys: Role of solution heat treat- ment显示文摘 | HAN Y SAMUEL A M DOTY H W | 2014 | Materials and Design2014，58，6： | 1 |
| 13 | High-purity water production with the latest modular electrodeionization technology 显示文摘 | Philippe Rychen Samuel Alonso Hans Peter | 1997 | Ultrapure Water1997，14，5： | 1 |
| 14 | Effect of pancreatic endotherapy on quality of life in chronic pancreatitis patients:A systematic review显示文摘BACKGROUND Pancreatic endotherapy provides treatment options for the management of chronic pancreatitis-related structural complications such as pancreatic duct stones,strictures,and pancreatic fluid collections.Most studies detailing endotherapy,however,have focused on technical success outcomes such as stone clearance or stricture resolution.AIM To review the effect of pancreatic endotherapy on patient-centered outcomes.METHODS Systematic review of studies examining pancreatic endotherapy.RESULTS A total of 13 studies including 3 randomized clinical trials were included.The majority of studies found an improvement in quality of life with pancreatic endotherapy.CONCLUSION While pancreatic endotherapy does appear to improve quality of life,there are clear gaps in knowledge regarding many pancreatic endotherapy modalities.Furthermore,qualitative analysis is lacking in these studies and further work is needed to elucidate the patient experience with pancreatic endotherapy. | Samuel Y Han Georgios I Papachristou Raj J Shah Darwin L Conwell | 2021 | World Journal of Gastrointestinal Endoscopy2021，13，8： | 1 |
| 15 | TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans -Signaling显示文摘 | Christoph Becker Massimo C. Fantini Christoph Schramm Hans A. Lehr Stefan Wirtz Alexei Nikolaev Jürgen Burg Susanne Strand Ralf Kiesslich Samuel Huber Hiroaki Ito Norihiro Nishimoto Kazuyuki Yoshizaki Tadamitsu Kishimoto Peter R. Galle Manfred Blessing St | 2004 | Immunity2004，，4： | 1 |
| 16 | N -Alkyl- N -methylpyrrolidinium difluoro(oxalato)borate ionic liquids: Physical/electrochemical properties and Al corrosion显示文摘 | Joshua L. Allen Dennis W. McOwen Samuel A. Delp Eric T. Fox James S. Dickmann Sang-Don Han Zin-Bin Zhou T. Richard Jow Wesley A. Henderson | 2013 | Journal of Power Sources2013，，： | 1 |
| 17 | Endoscopic retrograde cholangiopancreatography and liver biopsy in the evaluation of elevated liver function tests after liver transplantation显示文摘BACKGROUND Abnormal liver function tests(LFTs)in post-liver transplant(LT)patients pose a challenge in the timing and selection of diagnostic modalities.There are little data regarding the accuracy of endoscopic retrograde cholangiopancreatography(ERCP)and liver biopsy(LB)in diagnosing post-transplant complications.AIM To evaluate the diagnostic performance of ERCP and LB in patients with nonvascular post-LT complications.METHODS This single-center retrospective study evaluated patients undergoing both ERCP and LB for evaluation of elevated LFTs within 6 mo of LT from 2000 to 2017.Diagnostic operating characteristics including accuracy,sensitivity and specificity for various diagnoses were calculated for ERCP and LB.The R factor(ratio of alkaline phosphatase to alanine aminotransferase)was also calculated for each patient.RESULTS Of the 1284 patients who underwent LT,91 patients(74.7%males,mean age of 51)were analyzed.Anastomotic strictures(AS,24.2%),acute cellular rejection(ACR,11%)and concurrent AS/ACR(14.3%)were the most common diagnoses.ERCP carried an accuracy of 79.1%(95%CI:69.3-86.9),LB had an accuracy of 93.4%(95%CI:86.2-97.5),and the combination of the two had an accuracy of 100%(95%CI:96-100).There was no difference between patients with AS and ACR in mean R factor(AS:1.9 vs ACR:1.1,P=0.24).Adverse events did not differ between the two tests(ERCP:3.1%vs LB:1.1%,P=0.31).CONCLUSION In patients with abnormal LFTs after LT without vascular complications,the combination of LB and ERCP carries low risk and improves diagnostic accuracy over either test alone. | Augustin Attwell Samuel Han Michael Kriss | 2021 | World Journal of Hepatology2021，13，1： | 1 |
| 18 | TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans -Signaling显示文摘 | Christoph Becker Massimo C. Fantini Christoph Schramm Hans A. Lehr Stefan Wirtz Alexei Nikolaev Jürgen Burg Susanne Strand Ralf Kiesslich Samuel Huber Hiroaki Ito Norihiro Nishimoto Kazuyuki Yoshizaki Tadamitsu Kishimoto Peter R. Galle Manfred Blessing St | 2004 | Immunity2004，，4： | 1 |
| 19 | Update on endoscopic ultrasound-guided liver biopsy显示文摘Endoscopic ultrasound guided liver biopsy(EUS-LB)has emerged as a minimally-invasive alternative to the traditional(percutaneous or transjugular)liver biopsy techniques for the diagnosis of liver parenchymal diseases.Potentially,EUS-LB combines the advantages of percutaneous and transjugular liver biopsy in addressing focused sampling in addition to measuring portal pressure.Additionally,EUS-LB facilitates access to both the lobes of the liver which is not considered with the traditional percutaneous liver biopsy.Multiple studies have compared EUS-LB with conventional liver biopsy and reported comparable diagnostic yield,increased acquisition of complete portal tracts,and longer specimen length as compared to the traditional approaches.EUS-LB is associated with lesser post-procedural pain and shorter recovery time,while providing lower risk of complications when compared to traditional liver biopsy.Innovations in needle types,needle sizes and suction techniques have aimed at further optimizing the EUS-LB technique.This review article updates current literature with focus on the variations in the technique and equipment used for EUS-LB,and compares EUS-LB with traditional methods of liver biopsy. | Shiva Rangwani Devarshi R Ardeshna Khalid Mumtaz Sean G Kelly Samuel Y Han Somashekar G Krishna | 2022 | World Journal of Gastroenterology2022，28，28： | 1 |
| 20 | High-purity water production with the latest modular eleetrodeionization teehnology显示文摘 | Philippe R Samuel A Hans A | 1997 | Ultrapure Water1997，14，： | 1 |
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