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| 1 | Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis显示文摘Crohn's disease and ulcerative colitis evolve with a relapsing and remitting course.Determination of inflammatory state is crucial for the assessment of disease activity and for tailoring therapy.However,no simple diagnostic test for monitoring intestinal inflammation is available.Noninvasive markers give only indirect assessments of disease activity.Histopathological or endoscopical examinations accurately assess inflammatory activity,but they are invasive,time consuming and expensive and therefore are unsuitable for routine use.Imaging procedures are not applicable for ulcerative colitis.The usefulness of ultrasound and Doppler imag-ing in assessing disease activity is still a matter of discussion for Crohn's disease,and an increased interest in computed tomography enterograph (CTE) has been seen,mainly because it can delineate the extent and severity of bowel wall inflammation,besides detecting extraluminal findings.Until now,the available data concerning the accuracy of magnetic resonance enterography in detecting disease activity is less than CTE.Due to this,clinical activity indices are still commonly used for both diseases. | Eduardo Garcia Vilela Henrique Osvaldo da Gama Torres Fabiana Paiva Martins Maria de Lourdes de Abreu Ferrari Marcella Menezes Andrade Aloísio Sales da Cunha | 2012 | World Journal of Gastroenterology2012，18，9： | 23 |
| 2 | Injection of bone marrow mesenchymal stem cells by intravenous or intraperitoneal routes is a viable alternative to spinal cord injury treatment in mice显示文摘In spite of advances in surgical care and rehabilitation,the consequences of spinal cord injury(SCI)ar still challenging.Several experimental therapeutic strategies have been studied in the SCI field,and recen advances have led to the development of therapies that may act on the inhibitory microenvironment.As sorted lineages of stem cells are considered a good treatment for SCI.This study investigated the effect o systemic transplantation of mesenchymal stem cells(MSCs)in a compressive SCI model.Here we presen results of the intraperitoneal route,which has not been used previously for MSC administration after comveI.WeafC57BL/6nt lmy atb spinal cord compression for 1 minute with a 30-g vascular clip.The animals were divided into five groups DMEM at 7 days after SCI),DMEM i.v.(intravenous injection of 500μL of DMEM at 7 days after SCI)The effects of MSCs transplantation in white matter sparing were analyzed by luxol fast blue staining.Th number of preserved fibers was counted in semithin sections stained with toluidine blue and the presenc of trophic factors was analyzed by immunohistochemistry.In addition,we analyzed the locomotor perfor mance with Basso Mouse Scale and Global Mobility Test.Our results showed white matter preservation and a larger number of preserved fibers in the MSC groups than in the DMEM groups.Furthermore,th MSC groups had higher levels of trophic factors(brain-derived neurotrophic factor,nerve growth factor neurotrophin-3 and neurotrophin-4)in the spinal cord and improved locomotor performance.Our result indicate that injection of MSCs by either intraperitoneal or intravenous routes results in beneficial out comes and can be elected as a choice for SCI treatment. | Bruna dos Santos Ramalho FernANDa Martins de Almeida Conrado Mendonca Sales Silmara de Lima Ana Maria Blanco Martinez | 2018 | Neural Regeneration Research2018，13，6： | 12 |
| 3 | Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. | Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，7： | 10 |
| 4 | Parenteral fish oil as a pharmacological agent to modulate post-operative immune response: A randomized, double-blind, and controlled clinical trial in patients with gastrointestinal cancer显示文摘 | Raquel Susana Matos de Miranda Torrinhas Raquel Santana Thaís Garcia Maria Fernanda Cury-Boaventura Maria Mirtes Sales Rui Curi Dan Linetzky Waitzberg | 2013 | Clinical Nutrition2013，，4： | 3 |
| 5 | Dietary approach in the treatment of nonalcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD) has been identified as one of the most prevalent chronic liver disease in adults and children populations. NAFLD is usually associated with the metabolic syndrome(MS), which is chiefly related to insulin resistance and its consequences. Insulin resistance has a crucial role in the pathogenesis of hepatic steatosis and potentially nonalcoholic steatohepatitis(NASH). Because of the contemporary epidemics of MS and obesity, the burden of NAFLD is also expected to rise. Unhealthy diets, such as the so-called western diet, are enriched in fructose, trans-fatty acids and saturated fat and seem to be associated with the development of NAFLD. In human studies, certain dietary sugars, particularly fructose, are used as a substrate for lipogenesis leading to hepatic fatty infiltration, inflammation, and possibly fibrosis. Other investigations have shown that fat consumption especially cholesterol and trans/saturated fatty acids are also steatogenic and seem to increase visceral adiposity. The identification of specific dietary components that favor the development of NASH could be important for the management of this disorder. This review focuses on the effects of different dietary approaches to prevent and treat NAFLD emphasizing the macronutrients and energy composition. | Silvia Marinho Ferolla Luciana Costa Silva Maria de Lourdes Abreu Ferrari Aloísio Sales da Cunha Flaviano dos Santos Martins Cláudia Alves Couto Teresa Cristina Abreu Ferrari | 2015 | World Journal of Hepatology2015，7，24： | 2 |
| 6 | 石油中不同环数芳烃化合物的精细分离和制备显示文摘石油族组分的分离和制备过程是后续分子组成、同位素分析的基础。由于同分异构体多,传统技术制备的芳烃化合物组分仍然无法满足单体化合物的同位素分析要求。采用两种不同的分离方案对原油中的多环芳烃进行精细的分离和制备,其中'一步法'是直接将脱沥青质的原油样品经过一次氧化铝/硅胶层析柱,用不同体积比的石油醚/二氯甲烷混合溶剂进行洗脱;'两步法'先将原油采用常规的族组分分离方法得到芳烃馏分,再将芳烃馏分经氧化铝层析柱,用不同比例的石油醚/二氯甲烷混合溶剂进行洗脱,可得到不同环数芳烃的组分。对洗脱出来的不同组分进行色谱—质谱分析(GC-MS),与'一步法'相比,'两步法'可以更好地实现单环、双环与三环芳烃化合物的分离制备,其中,石油醚/二氯甲烷(99/1,V/V)的混合溶剂可以制备单环芳烃化合物;石油醚/二氯甲烷(9/1,V/V)混合溶剂可制备得到以双环芳烃化合物占绝对优势的组分;石油醚/二氯甲烷(8/2,V/V)混合溶剂则可制备得到三环芳烃化合物组分。 | 刘雪 李美俊 唐友军 何大祥 KONAN N’Guessan Francois De Sales 师生宝 朱雷 | 2021 | 石油实验地质2021，43，3： | 2 |
| 7 | Temperature conversion (mesophilic to thermophilic) of municipal sludge digestion 显示文摘 | De la Rubia M A Romero L I Sales D | 2005 | Aiche Journal2005，51，9： | 1 |
| 8 | Complications of Scoliosis Surgery in Prader-Willi Syndrome显示文摘 | Franck Accadbled Thierry Odent Alexandre Moine Edouard Chau Christophe Glorion Gwenaelle Diene Jér?me Sales de Gauzy | 2008 | Spine2008，，4： | 1 |
| 9 | Efficient Production of Hydrogen over Supported Cobalt Catalysts from Ethanol Steam Reforming 显示文摘 | Jordi Llorca Narcis Homs Joaquim Sales Pilar Ramtrez de la Piscina | 2002 | Catalysis2002，209，2： | 1 |
| 10 | Efficient production of hydrogen over supported cobalt catalysts from ethanol steam reforming 显示文摘 | LLORCA J HOMS N SALES J RAMIREZ de la PISCINA P | 2002 | J Catal2002，209，2： | 1 |
| 11 | Epidemiolo gy of aneurismal bone cysts in children: a rnulticenter study and literature review 显示文摘 | Cottalorda J Kohler R Sales de Gauzy J | 2004 | J Pediatr Orthop B2004，13，6： | 1 |
| 12 | Intervertebral disc modeling using a MRI method:Migration of the nucleus zone within scoliotic intervertebral discs显示文摘 | Perie D Sales de Gauzy J | 2001 | Mag Reson Imaging2001，19，9： | 1 |
| 13 | New insights into HLA-G mediated tolerance显示文摘 | Amodio G Sales De Albuquerque R Gregori S | 2014 | Tissue Antigens2014，84，3： | 1 |
| 14 | Effect of blend composition on microstructure, morphology and gas permeability in PU/ PMMA blends显示文摘 | Patricio P S O de Sales J A Silva G G | 2006 | Journal of Membrane Science2006，271，12： | 1 |
| 15 | Effects of blood flow restriction without additional exercise on strength reductions and muscular atrophy following immobilization:A systematic review显示文摘Purpose:To investigate whether blood flow restriction(BFR) without concomitant exercise mitigated strength reduction and atrophy of thigh muscles in subjects under immobilization for lower limbs.Methods:The following databases were searched:PubMed,CINAHL,PEDro,Web of Science,Central,and Scopus.Results:The search identified 3 eligible studies,and the total sample in the identified studies consisted of 38 participants.Isokinetic and isometric torque of the knee flexors and extensors was examined in 2 studies.Cross-sectional area of thigh muscles was evaluated in 1 study,and thigh girth was measured in 2 studies.The BFR protocol was 5 sets of 5 min of occlusion and 3 min of free flow,twice daily for approximately 2 weeks.As a whole,the included studies indicate that BFR without exercise is able to minimize strength reduction and muscular atrophy after immobilization.It is crucial to emphasize,however,that the included studies showed a high risk of bias,especially regarding allocation concealment,blinding of outcome assessment,intention-to-treat analyses,and group similarity at baseline.Conclusion:Although potentially useful,the high risk of bias presented by original stodies limits the indication of BFR without concomitant exercise as an effective countermeasure against strength reduction and atrophy mediated by immobilization. | Mikhail Santos Cerqueira Jose Diego Sales Do Nascimento Daniel Germano Maciel Jean Artur Mendonca Barboza Wouber Herickson De Brito Vieira | 2020 | Journal of Sport and Health Science2020，9，2： | 1 |
| 16 | Epidemiology of aneurysmal bone cyst in children: a multicenter study and litera- ture review显示文摘 | Cottalorda J Kohler R Sales de Gauzy J | 2004 | J Pediatr Orthop B2004，13，： | 1 |
| 17 | Concretes and mortars recycled with water treatment sludge and construction and demo- lition rubble显示文摘 | Almir Sales Francis Rodrigues de Souza | 2009 | Construction and Building Materials2009，2，6： | 1 |
| 18 | Wind hydrogen energy system and the gradual replacement of natural gas in the State of Ceará – Brazil显示文摘 | R.A. Patrício A.D. Sales E.M. Sacramento L.C. de Lima T.N. Veziroglu | 2012 | International Journal of Hydrogen Energy2012，，9： | 1 |
| 19 | Surgical treatment of radial neck fractures in children by intramedullary pinning显示文摘 | Ursei M Sales de Gauzy J Knorr J | 2006 | Acta Orthop Belg2006，72，2： | 1 |
| 20 | Impacts of global warming on southern California's winegrape climate suitability显示文摘Southern California has seen a resurgence of winegrowing regions in the past few decades,however the future of winegrape climatic suitability in the area has not been exhaustively explored.This study evaluated the future climate suitability for the cultivation of winegrape and potential global warming impacts on southern California's winegrowing regions through a series of high-resolution surface air temperature and precipitation projections obtained with the WRF-SSIB regional climate model.Results reveal that by mid-21st-century the surface air temperature will increase by approximately 1.2℃,while average precipitation will decrease by as much as 11%in the southern winegrowing areas under the Intergovernmental Panel on Climate Change high greenhouse-gas emissions scenario.Evaluation of bioclimatic suitability indices indicate increases in heat accumulation for all major winegrowing areas;including an increase of about 10% in growing-degree day,while morning low temperatures in September may experience increases of approximately 11% in the future,thus impacting negatively the ripening stage of grapevines and leading to changes in wine composition and quality.Additionally,the extent of areas classified under the cool to warm climate suitability categories could decrease by nearly 42% in the study area by 2050.Conditions in southern California are already warm and dry for viticulture and continuing heat accumulation increase,along with rainfall reduction,could potentially place additional stress to winegrape crop in the area,including advanced phenological timing and moisture deficit stress that could lead to decreases in yield.The projected decline in viticulture suitability highlights the need for adaptive capacity within this sector to mitigate the impacts of global warming.Possible mitigating strategies include planting hotter climate grape varieties,moving vineyards to regions that are more suitable in the future,and adopting dry-farming techniques. | Corrie MONTE VERDE Fernando DE SALES | 2020 | Advances in Climate Change Research2020，11，3： | 1 |
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