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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Parenteral fish oil as a pharmacological agent to modulate post-operative immune response: A randomized, double-blind, and controlled clinical trial in patients with gastrointestinal cancer显示文摘 | Raquel Susana Matos de Miranda Torrinhas Raquel Santana Thaís Garcia Maria Fernanda Cury-Boaventura Maria Mirtes Sales Rui Curi Dan Linetzky Waitzberg | 2013 | Clinical Nutrition2013，，4： | 3 |
| 3 | Postsurgical Infections are Reduced with Specialized Nutrition Support显示文摘 | Dan L. Waitzberg Hideaki Saito Lindsay D. Plank Glyn G. Jamieson Palepu Jagannath Tsann-Long Hwang Juan M. Mijares David Bihari | 2006 | World Journal of Surgery2006，，8： | 1 |
| 4 | Access routes for nutritional therapy显示文摘 | Waitzberg DL Plopper C Terra RM | 2000 | World J Surg2000，24，12： | 1 |
| 5 | New parenteral lipid emulsions for clinical use 显示文摘 | Waitzberg DL Torrinhas RS Jacintho TM | 2006 | JPEN J Parenter Enteral Nutr2006，30，4： | 1 |
| 6 | Fish oil lipid emulsions and immune response:what clinicians need to know显示文摘 | Waitzberg DL Torrinhas RS | 2009 | Nutr Clin Pract2009，24，4： | 1 |
| 7 | Hospital malnutrition: the Brazilian national surrey (IBRANUTRI) : a study of 4000 patients显示文摘 | WAITZBERG DL CAIAFFA WT CORREIA MI | 2001 | Nutrition2001，17，8： | 1 |
| 8 | Hospital malnutrition:the Brazilian national survey (ilbranutri) :a study of 4000 patients 显示文摘 | Waitzberg DL Caiaffa WT Correia MITD | 2001 | Nutrition2001，17，： | 1 |
| 9 | The impact of malnutrition on morbidity, mortality, length of hospital stay and costs evaluated through a multivariate model analysis显示文摘 | Correia MI Waitzberg DL | 2003 | Clin Nutr2003，22，： | 1 |
| 10 | Postoperative total parenteral nutrition显示文摘 | Waitzberg DL Plopper C Terra RM | 1999 | World J Surg1999，23，6： | 1 |
| 11 | Limitations and Validation of Bioelectrical Impedance Analysis in Morbidly Obese Patients显示文摘 | Coppini L Z Waitzberg D L Campos A C | 2005 | Curr Opin Clin Nutr MEtab Care2005，8，： | 1 |
| 12 | Hospital malnutrition: the Brazilian national survey ( IBRANUTRI): a study of 4000 patients显示文摘 | Waitzberg DL CaiafIa WT Correia MI | 2001 | Nutrition2001，，： | 1 |
| 13 | Efficacy of nutritional support: evidence-based nutri- tion and cost-effectiveness 显示文摘 | Waitzberg DL | 2002 | Nestel Nutr Workshop Ser Clin Perform Programme2002，7，： | 1 |
| 14 | Fish oil lipid emulsions and im- mune response: what clinicians need to know 显示文摘 | Waitzberg DL Torrinhas RS | 2009 | Nutr Clin Pract2009，24，4： | 1 |
| 15 | Nutritional assessment in the hospitalized patient 显示文摘 | Waitzberg D L Correia M I | 2003 | Curr Opin Clin Nutr Metab Care2003，6，5： | 1 |
| 16 | The impact of malnutrition on morbidity,mortality,length of hospital stay and costs evaluated through a multivariate model analysis 显示文摘 | Correia MI Waitzberg DL | 2003 | Clin Nutr2003，22，3： | 1 |
| 17 | Postsurgical Infections are Reduced with Specialized Nutrition Support显示文摘 | Dan L. Waitzberg MD Hideaki Saito MD Lindsay D. Plank PhD Glyn G. Jamieson MD Palepu Jagannath MD Tsann-Long Hwang MD Juan M. Mijares MD David Bihari MD | 2006 | World Journal of Surgery2006，，8： | 1 |
| 18 | The impact of malnutrition on morbidity, mortality,length of hospital stay and costs evaluated through a multivariate model analysis显示文摘 | Correia MI Waitzberg DL | 2003 | Clin Nutr2003，22，3： | 1 |
| 19 | The impact of malnutrition on morbidi- ty, mortality,length of hospital stay and costs evaluated through a multivariate model analysis显示文摘 | Correia MI Waitzberg DL | 2003 | Clin Nutr2003，22，3： | 1 |
| 20 | The impact of malnutrition on morbidity,mortality,length of hospital stay and costs evaluated through a multivariate model analysis显示文摘 | Correia MI Waitzberg DL | | 0，，03： | 1 |
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