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| 1 | Phase angle obtained by bioelectrical impedance analysis independently predicts mortality in patients with cirrhosis显示文摘AIM To evaluate the prognostic value of the phase angle(PA)obtained from bioelectrical impedance analysis(BIA) for mortality prediction in patients with cirrhosis. METHODS In total, 134 male cirrhotic patients prospectively completed clinical evaluations and nutritional assessment by BIA to obtain PAs during a 36-mo follow-up period. Mortality risk was analyzed by applying the PA cutoff point recently proposed as a malnutrition marker(PA ≤ 4.9°) in Kaplan-Meier curves and multivariate Cox regression models. RESULTS The patients were divided into two groups according to the PA cutoff value(PA > 4.9°, n = 73; PA ≤ 4.9°, n = 61). Weight, height, and body mass index were similar in both groups, but patients with PAs > 4.9° were younger and had higher mid-arm muscle circumference, albumin, and handgrip-strength values and lower severe ascites and encephalopathy incidences, interleukin(IL)-6/IL-10 ratios and C-reactive protein levels than did patients with PAs ≤ 4.9°(P ≤ 0.05). Forty-eight(35.80%) patients died due to cirrhosis, with a median of 18 mo(interquartile range, 3.3-25.6 mo) follow-up until death. Thirty-one(64.60%) of these patients were from the PA ≤ 4.9° group. PA ≤ 4.9° significantly and independently affected the mortality model adjusted for Model for End-Stage Liver Disease score and age(hazard ratio = 2.05, 95%CI: 1.11-3.77, P = 0.021). In addition, Kaplan-Meier curves showed that patients with PAs ≤ 4.9° were significantly more likely to die. CONCLUSION In male patients with cirrhosis, the PA ≤ 4.9° cutoff was associated independently with mortality and identified patients with worse metabolic, nutritional, and disease progression profiles. The PA may be a useful and reliable bedside tool to evaluate prognosis in cirrhosis. | Giliane Belarmino Maria Cristina Gonzalez Raquel S Torrinhas Priscila Sala Wellington Andraus Luiz Augusto Carneiro D'Albuquerque Rosa Maria R Pereira Valéria F Caparbo Graziela R Ravacci Lucas Damiani Steven B Heymsfield Dan L Waitzberg | 2017 | World Journal of Hepatology2017，9，7： | 11 |
| 2 | Parenteral fish oil as a pharmacological agent to modulate post-operative immune response: A randomized, double-blind, and controlled clinical trial in patients with gastrointestinal cancer显示文摘 | Raquel Susana Matos de Miranda Torrinhas Raquel Santana Thaís Garcia Maria Fernanda Cury-Boaventura Maria Mirtes Sales Rui Curi Dan Linetzky Waitzberg | 2013 | Clinical Nutrition2013，，4： | 3 |
| 3 | Partial replacement ofω-6fatty acids with medium-chain triglycerides,but not olive oil,improve colon cytokine response and damage in experimental colitis显示文摘 | Bertevello PL De Nardi L Torrinhas RS | 2012 | JPEN J Parenter Enteral Nutr2012，36，4： | 1 |
| 4 | New parenteral lipid emulsions for clinical use 显示文摘 | Waitzberg DL Torrinhas RS Jacintho TM | 2006 | JPEN J Parenter Enteral Nutr2006，30，4： | 1 |
| 5 | Fish oil lipid emulsions and immune response:what clinicians need to know显示文摘 | Waitzberg DL Torrinhas RS | 2009 | Nutr Clin Pract2009，24，4： | 1 |
| 6 | TGF - β1 expression in wound healing is acutely affected by exper- imental malnutrition and early enteral feeding 显示文摘 | Alves CC Torrinhas RS Giorgi R | 2012 | Int Wound J2012，11，2： | 1 |
| 7 | Commercial squids : Characterization,assessment of potential health benefits/risks and discrimination based on mineral, lipid and vitamin E concentrations 显示文摘 | Torrinha A Gomes F Oliveira M el al | 2014 | Food and Chemical Toxicology2014，67，5： | 1 |
| 8 | Fish oil lipid emulsions and im- mune response: what clinicians need to know 显示文摘 | Waitzberg DL Torrinhas RS | 2009 | Nutr Clin Pract2009，24，4： | 1 |
| 9 | Par-enteral fish oil as a pharmacological agent to modulate post-operative immune response : a randomized, double-blind,and controlled clinical trial in patients with gastrointestinalcancer显示文摘 | de Miranda Torrinhas RS Santana R Garcia T | 2013 | Clin Nutr2013，32，4： | 1 |
| 10 | New parenteral lipid emulsions for clinical use显示文摘 | Waitzberg DL Torrinhas RS Jacintho TM | 2006 | J Parenteral Enteral Nutr2006，30，4： | 1 |
| 11 | Fish oil lipid emulsions and immune re- sponse:what clinicians need to know 显示文摘 | Waitzberg DL Torrinhas RS | 2009 | Nutr Clin Pract2009，24，4： | 1 |
| 12 | Fish oil lipid emulsions and immune response: what clinicians need to know 显示文摘 | Waitzberg DL Torrinhas RS | 2009 | Nutr Clin Pract2009，24，4： | 1 |
| 13 | New parenteral lipid emulsions for clinical use 显示文摘 | Waitzberg DL Torrinhas RS Jacintho TM | 2006 | J Parenter Enteral Nutr2006，30，4： | 1 |
| 14 | Preoperative diagnosis of sus- picious:parathyroid adenomas by RT-PCR using mRNA extracted from leftover cells in a needle used for ultra- sonically guided fine needle aspiration cytology显示文摘 | Cavaco B M Torrinha F Mendon:a E Pratas S Boavi- da J Sobrinho L G | 2003 | Ac- ta Cytol2003，47，： | 1 |
| 15 | New parenterallipid emulsions for clinical use 显示文摘 | Waitzberg DL Torrinhas RS Jacintho TM | 2006 | Parenteral Enteral Nutr2006，30，4： | 1 |
| 16 | Effect of glutamine dipeptide on hepatic regeneration in partially hepatectomized malnourished rats显示文摘 | Passos de Jesus Mazza Rosfingela Bertevello Pedro Lais Matos de Miranda Torrinhas Raquel | 2003 | Nu- trition( Burbank Los Angeles County Calif)2003，19，1112： | 1 |
| 17 | New parenteral lipid e-mulsions for clinical use显示文摘 | Waitzberg DL Torrinhas RS Jacintho TM | 2006 | JPEN J Parenter Enteral Nutr2006，30，4： | 1 |
| 18 | Com- plementarity of Subjective Global Assessment (SGA) and Nutri- tional Risk Screening 2002 ( NRS 2002) for predicting poor clini- cal outcomes in hospitalized patients 显示文摘 | RASLAN M GONZALEZ M C TORRINHAS R S | 2011 | Clin Nutr2011，30，1： | 1 |
| 19 | Newparenteral lipid emulsions for clinical use显示文摘 | Waitzberg DL Torrinhas RS Jacintho TM | | 0，，04： | 1 |
| 20 | TGF - 131 expression in wound healing is acutely affected by experimental malnutrition and early enteral feeding显示文摘 | Alves CC Torrinhas RS Giorgi R | 2014 | Int Wound J2014，11，5： | 1 |
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