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1Evaluation of inflammatory activity in Crohn's disease and ulcerative colitis显示文摘Crohn's disease and ulcerative colitis evolve with a relapsing and remitting course.Determination of inflammatory state is crucial for the assessment of disease activity and for tailoring therapy.However,no simple diagnostic test for monitoring intestinal inflammation is available.Noninvasive markers give only indirect assessments of disease activity.Histopathological or endoscopical examinations accurately assess inflammatory activity,but they are invasive,time consuming and expensive and therefore are unsuitable for routine use.Imaging procedures are not applicable for ulcerative colitis.The usefulness of ultrasound and Doppler imag-ing in assessing disease activity is still a matter of discussion for Crohn's disease,and an increased interest in computed tomography enterograph (CTE) has been seen,mainly because it can delineate the extent and severity of bowel wall inflammation,besides detecting extraluminal findings.Until now,the available data concerning the accuracy of magnetic resonance enterography in detecting disease activity is less than CTE.Due to this,clinical activity indices are still commonly used for both diseases.Eduardo Garcia Vilela Henrique Osvaldo da Gama Torres Fabiana Paiva Martins Maria de Lourdes de Abreu Ferrari Marcella Menezes Andrade Aloísio Sales da Cunha 2012World Journal of Gastroenterology2012,18,9:23
2Hongda New Material Improved Silicone Rubber Industrial Chain显示文摘Jiangsu Hongda Chemical New Material Co.,Ltd.(Hongda New material,SZ:002211)is located in Yangzhong,Jiangsu province.It got listed in Shenzhen Stock Exchange onFebruary 1st,2008.(CCR2008, No.3)The company mainly produces silicone monomersand high-temperature silicone rubber series.The capacity of silicone monomers and prod-ucts of silicone rubber series reached 30 000 t/a and 28 000 t/a respectively at the end of2007.The sales volume of high-temperature silicone rubber compound has grown steadilyat 30% a year.The company’s high-temperature silicone rubber capacity is still beingexpanded today and will hopefully reach 50 000 t/a at the end of 2008. 2008China Chemical Reporter2008,,25:16
3Injection of bone marrow mesenchymal stem cells by intravenous or intraperitoneal routes is a viable alternative to spinal cord injury treatment in mice显示文摘In spite of advances in surgical care and rehabilitation,the consequences of spinal cord injury(SCI)ar still challenging.Several experimental therapeutic strategies have been studied in the SCI field,and recen advances have led to the development of therapies that may act on the inhibitory microenvironment.As sorted lineages of stem cells are considered a good treatment for SCI.This study investigated the effect o systemic transplantation of mesenchymal stem cells(MSCs)in a compressive SCI model.Here we presen results of the intraperitoneal route,which has not been used previously for MSC administration after comveI.WeafC57BL/6nt lmy atb spinal cord compression for 1 minute with a 30-g vascular clip.The animals were divided into five groups DMEM at 7 days after SCI),DMEM i.v.(intravenous injection of 500μL of DMEM at 7 days after SCI)The effects of MSCs transplantation in white matter sparing were analyzed by luxol fast blue staining.Th number of preserved fibers was counted in semithin sections stained with toluidine blue and the presenc of trophic factors was analyzed by immunohistochemistry.In addition,we analyzed the locomotor perfor mance with Basso Mouse Scale and Global Mobility Test.Our results showed white matter preservation and a larger number of preserved fibers in the MSC groups than in the DMEM groups.Furthermore,th MSC groups had higher levels of trophic factors(brain-derived neurotrophic factor,nerve growth factor neurotrophin-3 and neurotrophin-4)in the spinal cord and improved locomotor performance.Our result indicate that injection of MSCs by either intraperitoneal or intravenous routes results in beneficial out comes and can be elected as a choice for SCI treatment.Bruna dos Santos Ramalho FernANDa Martins de Almeida Conrado Mendonca Sales Silmara de Lima Ana Maria Blanco Martinez 2018Neural Regeneration Research2018,13,6:12
4Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects.Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha 2017Asian Pacific Journal of Tropical Medicine2017,10,7:10
5Acute effects of physical exercise in type 2 diabetes: A review显示文摘The literature has shown the efficiency of exercise in the control of type 2 diabetes(T2D), being suggested as one of the best kinds of non-pharmacological treatments for its population. Thus, the scientific production related to this phenomenon has growing exponentially. However, despite its advances, still there is a lack of studies that have carried out a review on the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in individuals with T2 D, not to mention that in a related way, these themes have been very little studied today. Therefore, the aim of this study was to organize and analyze the current scientific production about the acute effects of physical exercise on metabolic and hemodynamic markers and possible control mechanisms of these indicators in T2 D individuals. For such, a research with the following keywords was performed:-exercise; diabetes and post-exercise hypotension; diabetes and excess post-exercise oxygen consumption; diabetes and acute effects in PUBMED, SCIELO and HIGHWIRE databases. From the analyzed studies, it is possible to conclude that, a single exercise session can promote an increase in the bioavailability of nitric oxide and elicit decreases in postexercise blood pressure. Furthermore, the metabolic stress from physical exercise can increase the oxidation of carbohydrate during the exercise and keep it, in high levels, the post exercise consumption of O2, this phenomenon increases the rate of fat oxidation during recovery periods after exercise, improves glucose tolerance and insulin sensitivity and reduces glycemia between 2-72 h, which seems to be dependent on the exercise intensity and duration of the effort.Ricardo Yukio Asano Marcelo Magalhes Sales Rodrigo Alberto Vieira Browne José Fernando Vila Nova Moraes Hélio José Coelho Júnior Milton Rocha Moraes Hebert Gustavo Simoes 2014World Journal of Diabetes2014,5,5:8
6光纤复合架空地线(OPGW)雷击试验及分析显示文摘就IEC60794.4.1标准所描述的雷击试验要求,对不同OPGW光缆设计进行了研究,并分析了雷击对不同OPGW缆型的影响。提高连续电流———组成部分C(最具破坏性的部分)的电荷转移量,光缆的残余抗拉强度将随之降低。当电荷转移量大于100C时,光缆被损坏程度更多地取决于光缆的直径而不是外层绞线的直径。试验结果表明,为了设计出可靠并经济的OPGW光缆,我们必须综合考虑OPGW的机械性能和依据安装地的年雷暴日水平所必需的抗雷击性能。Liuis-R Sales Josep Martin Allesandro Ginocchio 2004电力系统通信2004,25,5:7
7基于匹配滤波解调的多芯Bragg光栅曲率传感器显示文摘设计了一种多芯光纤Bragg光栅曲率传感器,并采用匹配滤波技术实现曲率解调。多芯光纤Bragg光栅曲率传感器是通过在多芯光纤的两个中心对称纤芯中写入Bragg光栅实现的。两个光纤Bragg光栅具有相似的反射谱和中心波长,当多芯光纤发生弯曲时,两个光纤Bragg光栅的反射谱叠加区域将发生改变。将两个光纤Bragg光栅构造成匹配滤波模式,则两个光纤Bragg光栅反射谱的叠加区域面积决定了输出信号的光强,而叠加区域的面积与光纤曲率有关。因此,通过测量匹配滤波信号的功率可以实现曲率解调。结果表明,匹配滤波技术能有效解调多芯光纤Bragg光栅曲率传感器,最大曲率解调灵敏度为0.78mW·m^(-1)。此外,测量了多芯光纤Bragg光栅曲率传感器在不同轴向应变和环境温度下的解调性能,结果表明,该曲率解调系统具有很强的抵抗外界环境波动的能力。郑狄 潘炜 Sales Salvador 2018光学学报2018,38,3:7
8Stability characteristics of shallow landslide triggered by rainfall显示文摘Rainfall induced shallow landslides are known to be extremely dangerous since the sliding mass can propagate quickly and travel far from the source. Although the sliding mechanism in sloping ground is simple to understand, the problem may be complicated by unsaturated transient water flow. The flow behavior of rainwater in unsaturated sloping ground and the consequent factor of safety must be clearly understood to assess slope stability under rainfall conditions. A series of laboratory experiments was conducted to examine the critical hydrological states so that assessment of slope stability under rainfall condition can be performed. Based on the test results, a unique relationship between critical hydrological states, rainfall intensity, and soil properties was formulated. Sequential stability analysis provided insights into the stability of slopes subjected to variations in soil properties, slope angles and rainfall intensities, and the consequent variation in the depth of the failure plane, vital in landslide risk assessment, was determined through this analysis.The variation of rainfall intensity was found to strongly affect the depth of the failure plane in cohesionless sloping ground. Furthermore, the influence of rainfall intensity on the depth of the failure plane may be alleviated by a small magnitude of cohesive strength. The results of this study will reinforce knowledge of landslide behavior and help to improve mitigation measures in susceptible areas.Avirut CHINKULKIJNIWAT Taworn TIRAMETATIPARAT Chanathip SUPOTAYAN Somjai YUBONCHIT Suksun HORPIBULSUK Rattana SALEE Panich VOOTTIPRUEX 2019Journal of Mountain Science2019,16,9:4
9Soil and water conservation measures improve soil carbon sequestration and soil quality under cashews显示文摘Land degradation is becoming a serious problem in the west coast region of India where one of the world's eight biodiversity hotspots,the‘Western Ghats’,is present.Poor land management practices and high rainfall have led to increasing problems associated with land degradation.A long-term(13-year)experiment was done to evaluate the impact of soil and water conservation measures on soil carbon sequestration and soil quality at three different depths under cashew nut cultivation on a 19%slope.Five soil and water conservation measures-continuous contour trenches,staggered contour trenches,halfmoon terraces,semi-elliptical trenches,and graded trenches all with vegetative barriers of Stylosanthes scabra and Vetiveria zizanoides and control were evaluated for their influence on soil properties,carbon sequestration,and soil quality under cashews.The soil and water conservation measures improved significantly the soil organic carbon,soil organic carbon stock,carbon sequestration rate and microbial activity compared to the control condition(without any measures).Among the measures tested,continuous contour trenches with vegetative barriers outperformed the others with respect to soil organic carbon stock,sequestration rate,and microbial activity.The lower metabolic quotient with the measures compared to the control indicated alleviation of environmental stress on microbes.Using principal component analysis and a correlation matrix,a minimum dataset was identified as the soil available nitrogen,bulk density,basal soil respiration,soil pH,acid phosphatase activity,and soil available boron and these were the most important soil properties controlling the soil quality.Four soil quality indices using two summation methods(additive and weighted)and two scoring methods(linear and non-linear)were developed using the minimum dataset.A linear weighted soil quality index was able to statistically differentiate the effect of soil and water conservation measures from that of the control.The highest value of the soil quality index of 0.98 was achieved with continuous contour trenches with a vegetative barrier.The results of the study indicate that soil and water conservation measures for cashews are a potential strategy to improve the soil carbon sequestration and soil quality along with improving crop productivity and reducing the erosion losses.Gopal Ramdas Mahajan Bappa Das Sandrasekaran Manivannan Begur Lakshminarasimha Manjunath Ram Ratan Verma Sujeet Desai Rahul Mukund Kulkarni Ashish Marotrao Latare Reshma Sale Dayesh Murgaonkar Kiran Puna Patel Shaiesh Morajkar Ashwini Desai Natasha Barnes Heena Mulla 2021International Journal of Sediment Research2021,36,2:4
10GO FAIR Brazil:A Challenge for Brazilian Data Science显示文摘The FAIR principles,an acronym for Findable,Accessible,Interoperable and Reusable,are recognised worldwide as key elements for good practice in all data management processes.To understand how the Brazilian scientific community is adhering to these principles,this article reports Brazilian adherence to the GO FAIR initiative through the creation of the GO FAIR Brazil Office and the manner in which they create their implementation networks.To contextualise this understanding,we provide a brief presentation of open data policies in Brazilian research and government,and finally,we describe a model that has been adopted for the GO FAIR Brazil implementation networks.The Brazilian Institute of Information in Science and Technology is responsible for the GO FAIR Brazil Office,which operates in all fields of knowledge and supports thematic implementation networks.Today,GO FAIR Brazil-Health is the first active implementation network in operation,which works in all health domains,serving as a model for other fields like agriculture,nuclear energy,and digital humanities,which are in the process of adherence negotiation.This report demonstrates the strong interest and effort from the Brazilian scientific communities in implementing the FAIR principles in their research data management practices.Luana Sales Patricia Henning Viviane Veiga Maira Murrieta Costa Luis Fernando Sayao Luiz Olavo Bonino da Silva Santos Luis Ferreira Pires 2020Data Intelligence2020,2,1:3
11Parenteral fish oil as a pharmacological agent to modulate post-operative immune response: A randomized, double-blind, and controlled clinical trial in patients with gastrointestinal cancer显示文摘Raquel Susana Matos de Miranda Torrinhas Raquel Santana Thaís Garcia Maria Fernanda Cury-Boaventura Maria Mirtes Sales Rui Curi Dan Linetzky Waitzberg 2013Clinical Nutrition2013,,4:3
12Axial superresolution with phase-only pupil filters显示文摘T Sales R M Morris G M 1998Opt Commun1998,156,:2
13Filled Skutterudite antimonides: A new class of thermoelectric materials 显示文摘Sales B C Mandrus D Williams R K 1996Science1996,3,1272:2
14Dietary approach in the treatment of nonalcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD) has been identified as one of the most prevalent chronic liver disease in adults and children populations. NAFLD is usually associated with the metabolic syndrome(MS), which is chiefly related to insulin resistance and its consequences. Insulin resistance has a crucial role in the pathogenesis of hepatic steatosis and potentially nonalcoholic steatohepatitis(NASH). Because of the contemporary epidemics of MS and obesity, the burden of NAFLD is also expected to rise. Unhealthy diets, such as the so-called western diet, are enriched in fructose, trans-fatty acids and saturated fat and seem to be associated with the development of NAFLD. In human studies, certain dietary sugars, particularly fructose, are used as a substrate for lipogenesis leading to hepatic fatty infiltration, inflammation, and possibly fibrosis. Other investigations have shown that fat consumption especially cholesterol and trans/saturated fatty acids are also steatogenic and seem to increase visceral adiposity. The identification of specific dietary components that favor the development of NASH could be important for the management of this disorder. This review focuses on the effects of different dietary approaches to prevent and treat NAFLD emphasizing the macronutrients and energy composition.Silvia Marinho Ferolla Luciana Costa Silva Maria de Lourdes Abreu Ferrari Aloísio Sales da Cunha Flaviano dos Santos Martins Cláudia Alves Couto Teresa Cristina Abreu Ferrari 2015World Journal of Hepatology2015,7,24:2
15Diffractive superresolution elements显示文摘T Sales R M Morris G M 1997J Opt Soc Am A1997,14,7:2
16基于微波光子的光纤传感解调技术(特邀)显示文摘光纤传感器因其具有抗电磁干扰、耐腐蚀、质量轻、体积小、精度高和易于复用等诸多优点,已广泛应用于航空航天、石油化工、电子电力、土木工程和生物医药等领域。传统的光纤传感解调技术存在精度低、速度慢和稳定性差等缺点。为解决此问题,近年来,基于微波光子学的传感与解调技术引起了科研人员的广泛关注。文章系统地回顾了基于微波光子学的光纤传感解调技术的研究进展,介绍了多种微波光子传感解调方案及其工作原理,并对未来的研究和发展方向进行了探讨。郑狄 邹喜华 潘炜 Sales Salvador 2018光通信研究2018,,6:2
17Immunohistochemical study of the digestive tract of Oligosarcus hepsetus显示文摘AIM: To describe the histology of the digestive tract and to investigate the occurrence of endocrine cells in Oligosarcus hepsetus (O. hepsetus ). METHODS: The digestive tract (DT) of O. hepsetus was divided into esophagus, two stomach regions (glandular and non-glandular) and two intestinal regions (anterior and posterior). These specimens were processed by routine histological techniques and stained with hematoxylin-eosin, Gomori's trichrome, periodic acid Schiff (PAS) and Alcian blue (AB). An immunohistochemical method using avidin-biotin-peroxidase was employed.RESULTS: The esophagus is lined with a non-keratinized stratified squamous epithelium that is reactive to PAS and AB. The stomach has a mucosa lined with a simple columnar epithelium with mucus-secreting cells that are reactive only to PAS. The intestine has a simple columnar epithelium with a brush border and goblet cells that are reactive to PAS and AB. Somatostatin, serotonin and cholecystokinin immunoreactive cells were identified throughout the DT.CONCLUSION: This study revealed adaptations for the species' diet and showed that the distribution and relative frequency of immunoreactive cells are similar to those of other fish.Danielle A Vieira-Lopes Nadja L Pinheiro Armando Sales Adriana Ventura Francisco G Araújo Iracema D Gomes Aparecida A Nascimento 2013World Journal of Gastroenterology2013,19,12:2
1816 S rRNA survey revealed complex bacterial communities and evidence of bacterial interference on human adenoids显示文摘Tiantian Ren Dominique Ulrike Glatt Tam Nhu Nguyen Emma Kaitlynn Allen Stephen V. Early Michele Sale Birgit Winther Martin Wu 2012Environ Microbiol2012,,2:2
19Filled skutterudite antimonides :A new class of thermoelectric materials 显示文摘Sales B C Mandrus D Williams R K 1996Science1996,292,5266:2
20Apoptosis and colorectal cancer: implications for therapy显示文摘Shi Yu Yang Kevin M. Sales Barry Fuller Alexander M. Seifalian Marc C. Winslet 2009Trends in Molecular Medicine2009,,5:2
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