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| 1 | Pericardiocentesis with cisplatin for malignant pericardial effusion and tamponade显示文摘AIM:To evaluate the role and outcome of pericardiocentesis with intrapericardial cisplatin instillation for malignant pericardial effusion resulting from esophageal cancer. METHODS:We retrospectively studied 7 patients who underwent pericardiocentesis with intrapericardial cisplatin instillation for malignant pericardial effusion resulting from esophageal cancer.After pericardiocentesis,we performed catheterization of the pericardial space under ultrasonogram guidance.Malignant etiology of the pericardial fluid was confirmed by cytological examination.Subsequently,cisplatin(10 mg in 20 mL normal saline) was instilled into the pericardial space. RESULTS:The mean total volume of the aspirated effusion fluid was 782±264 mL(range,400-1200 mL) . The drainage catheter was successfully removed in all patients,and the mean duration of pericardial drainagewas 7.7±2.7 d(range,5-13 d) .No fluid reaccumulation was observed.Mean survival time was 120±71 d(range,68-268 d) . CONCLUSION:Pericardiocentesis along with catheter drainage appears to be a safe and effective for pericardial malignant effusion and tamponade,and cisplatin instillation prevents recurrence. | Takatsugu Oida Kenji Mimatsu Hiso Kano Atsushi Kawasaki Youichi Kuboi Nobutada Fukino Sadao Amano | 2010 | World Journal of Gastroenterology2010，16，6： | 19 |
| 2 | 手术期间血糖控制对糖尿病视网膜病变和黄斑病变的影响显示文摘目的:评估手术期间血糖控制对糖尿病视网膜病变和黄斑病变进展的影响。 | Chikako Suto Sadao Hori SatoshI Kato Kanemitsu Muraoka Shigehiko Kitano 刘亮(译) | 2006 | 美国医学会眼科杂志(中文版)2006，18，4： | 16 |
| 3 | Innovative use of controlled availability fertilizers with high performance for intensive agriculture and environmental conservation显示文摘A variety of slow release fertilizers, controlled release (availability) fertilizers (CAFs),and stability fertilizers have been developed in response to the serious drawbacks of the conventional fertilizers since the early 1960's. Of these fertilizers, CAFs which are coated with resin are consumed in the largest quantity in the world. Selecting CAFs with higher performance, the author will discuss about: 1) Innovation of agro-technologies for various field crops including new concepts of fertilizer application, 2) high yielding of field crops, 3) enhancing quality and safety of farm products, and 4) controlling the adverse effect of intensive agriculture on the environment. | Sadao SHOJI | 2005 | Science China(Life Sciences)2005，48，z2： | 14 |
| 4 | 超声波辅助农杆菌介导CP基因转化番小瓜(Carioca papaya L.)的有效方法显示文摘本研究探索了通过农杆菌介导,超声波辅助处理,转化番木瓜胚性愈伤组织,获得转基因植株的有效方法。分别将含有日本PLDMV 外壳蛋白基因(PTi-Epj-TL-PLDMV)和含有台湾PRSV 菌株、美国夏威夷PRSV 菌株、泰国PRSV 菌株及日本PLDMV 菌株的多元外壳蛋白基因编码序列(PTi-NP-YKT)插入双元载体质粒pGA482G,借助于农杆菌系LBA4404将双元载体上的外壳蛋白基因和新霉素磷酸转移酶基因(nptⅡ)转移到番木瓜品种Sunset 的胚性愈伤组织中,从而获得抗卡那霉素的转化再生植株。试验着重在转化方法上进行探索。结果表明,农杆菌过夜培养后,用高渗透压培养液(1/2 MS+6%蔗糖+1%葡萄糖,pH 5.7)调整至光密度OD_(600(?)m)=0.15-0.20,然后用该菌液感染材料30min,其间辅以超声波处理,可以大大提高转化效率。用15ml 无菌离心管装载胚性愈伤材料进行15s 的超声波处理,在80块被转化的胚性愈伤中获得21个CP 基因G 转化系(26.3%),而在对照处理64块胚性愈伤中仅获得1个转化系(1.6%);在经过15s 的超声波处理48块被转化的胚性愈伤中获得8个CP 基因B 转化系(16.7%),而在对照处理25块胚性愈伤中未出现转化系。上述操作方法用在两种CP 基因转化上均表现出相似的效果。试验还表明:120mg/L 是卡那霉素抗性筛选的最佳浓度。抗性筛选9个月后,在421块胚性愈伤组织中产生了42个抗卡那霉素的转化系。所获得的转基因植株分别用PCR 和Southern 印迹杂交进行了鉴定。 | 姜玲 MAOKA Tetsuo KOMORI Sadao FUKAMACHI Hiroshi KATO Hidenori OGAWA Kazunori | 2004 | 实验生物学报2004，37，3： | 11 |
| 5 | 应用气相色谱-质谱大体积进样负化学电离法测定河水中的有机氯农药显示文摘叙述了使用程序升温汽化 (PTV)、大体积进样 (L VI)、负化学电离 (NICI)的气质联用 (GC/ MS)条件测定 2 4种有机氯农药的方法。离子源温度设在 15 0℃ ,这也是 NICI选择离子监测 (SIM)的最佳温度。 PTV进样参数也设在最佳状态。不分流 - GC- NICI- MS法测定农药的灵敏度比不分流 - GC- EI- MS法高出约 7.8~36 0倍。分流 - L VI- GC- NICI- MS法又比不分流 - GC- NICI- MS法的灵敏度要高 80倍以上。本文介绍用分流 -L VI- GC- NICI- MS法对河水中的农药进行测定 ,并采用微液 -液萃取法对样品进行前处理。在河水样品中添加 2 ng/ l和 2 0 ng/ l的农药标准品并测得添加回收率分别为 75 %~ 111% (RSD:2 .9%~ 15 % )和 92 %~10 5 % (RSD:0 .5 %~ 5 .6 % ) ,方法检测限范围为 0 .0 0 4~ 2 .2 ng/ l。 | Sadao Nakamura 程雪梅 | 2002 | 热带农业工程2002，27，4： | 7 |
| 6 | Spatial and Temporal Changes of Floating Population in China Between 1990 and 2000显示文摘By studying the county-level census data of 1990 and 2000, we analyzed the spatial and temporal changes in the floating population in China between 1990 and 2000. The results of the analysis revealed the following characteris- tics. First, the spatial distribution of the migrants (referred to as 'floaters' in this paper) became increasingly concentrated in the cities during the 1990s. Second, the number of floaters increased rapidly during this period, and the area in which the floaters settled expanded quickly into four population explosion belts: the coast, the Changjiang River Delta, the Beijing-Guangzhou Railway and national border belts. Third, the number of inter-province floaters increased rapidly and exceeded that of intra-province floaters in the 1990s. In addition, to obtain a quantitative relationship between the number of floaters and 10 socio-economic variables by using statistical methods and also to find the chiefly important pulling factors of the migration destination, the authors selected approximately 100 cities with the largest population of floaters. Consequently, we found that four factors-GDP, passenger trips per 10,000 persons, per capita GDP and foreign direct investment-could provide an explanation for 83.7% of the number of floaters in 2000. The GDP showed the highest correlation with the number of floaters, suggesting that a highly developed economy is the most important factor that attracts floaters. Furthermore, a fairly close relationship between the number of floaters and the GDP was also found in 2000 for all the counties. | LIU Chen Kuninori OTSUBO WANG Qinxue Toshiaki ICHINOSE Sadao ISHIMURA | 2007 | Chinese Geographical Science2007，17，2： | 5 |
| 7 | Impaction of a lithotripsy basket during endoscopic lithotomy of a common bile duct stone显示文摘The treatments for common bile duct (CBD) stones are being continually developed. Impaction of the lithotripsy basket during endoscopic removal of CBD stones was seen in 5.9% patients. We report the case of a 66-yearold woman who underwent surgery for the removal of an impacted biliary basket. She was admitted to our hospital with a complaint of right upper abdominal pain. Magnetic resonance cholangiopancreatography revealed a CBD stone (20 mm × 15 mm). We diagnosed her with choledocholithiasis and performed endoscopic retrograde cholangiopancreatography to remove the stone. However, unfortunately, the retrievable basket around the stone became impacted. An endotriptor along with forceps could not be used owing to the entrapment of the basket, and thus we performed urgent surgery. The basket containing the stone was removed through a longitudinal choledochotomy. The wires leading to the basket were cut, and the basket containing the stone was removed via the incision. A T-tube was inserted,and the choledochotomy was closed. The postoperative course was uneventful. In conclusion, if the diameter of a CBD stone is more than 20 mm, then the risk of basket impaction increases, and surgery may be necessary as the initial treatment of the CBD stone. | Nobutada Fukino Takatsugu Oida Atsushi Kawasaki Kenji Mimatsu Youichi Kuboi Hisao Kano Sadao Amano | 2010 | World Journal of Gastroenterology2010，16，22： | 3 |
| 8 | Multicenter phase II study of the CyclOBEAP (CHOP-like + etoposide and bleomycin) regimen for patients with poor-prognosis aggressive lymphoma显示文摘 | Nozomi Niitsu Masataka Okamoto Sadao Aoki Hirokazu Okumura Tadashi Yoshino Ikuo Miura Masami Hirano | 2006 | Annals of Hematology2006，，6： | 2 |
| 9 | Pneumatosis cystoides intestinalis after fluorouracil chemotherapy for rectal cancer显示文摘Pneumatosis cystoides intestinalis (PCI) is a relatively rare condition characterized by intraluminal gas in the gastrointestinal tract. Several chemotherapeutic agents have been reported to be associated with PCI, although fluorouracil-related PCI is extremely rare. We report a case of a 76-year old man who received adjuvant chemotherapy for rectal cancer with fluorouracil (FU) and leucovorin (LV). After 1 cycle of the treatment, he presented with diarrhea and abdominal pain. Abdominal radiogram revealed the presence of free air under the diaphragm and intramural gas in the intestine. Laparotomy was performed, showing a suspected diagnosis of perforation in the gastrointestinal tract. Intraoperative findings revealed penumatosis of the intestine without evidence of perforation. He was treated supportively and his symptoms improved. In conclusion, we should consider the possibility of PCI occurring in patients with malignancies during chemotherapy treatment. | Kenji Mimatsu Takatsugu Oida Atsushi Kawasaki Hisao Kano Youichi Kuboi Osamu Aramaki Sadao Amano | 2008 | World Journal of Gastroenterology2008，14，20： | 2 |
| 10 | Upregulation of TRPC1 in the development of cardiac hypertrophy显示文摘 | Takayoshi Ohba Hiroyuki Watanabe Manabu Murakami Yoichiro Takahashi Kenji Iino Sadao Kuromitsu Yasuo Mori Kyoichi Ono Toshihiko Iijima Hiroshi Ito | 2006 | Journal of Molecular and Cellular Cardiology2006，，3： | 2 |
| 11 | 合成昆虫性信息素用于害虫防治的进展显示文摘虽然合成有机农药已在农业生产中起重要作用,但也带来诸如食用作物残留、害虫机体农药抗性发展等消极影响。在这样的情况下,远比常规化学杀虫剂更安全更富选择性的合成性信息素无疑是一种有希望可供选择的手段。 1971年,日本已验明小卷叶蛾类和桔黄小卷叶蛾同属昆虫性信息素成份。此后,随着微量化学技术令人瞩目的进展,现已验明50多种害虫信息素的化学成份,并广泛用于昆虫行为研究和田间试验,试验结果表明应用昆虫合成性信息素是可行的。 | Sadao Wakamura 周红晞 | 1993 | 农药译丛1993，15，4： | 2 |
| 12 | Vitreous levels of interleukin-6 and vascular endothelial growth factor are related to diabetic macular edema显示文摘 | Hideharu Funatsu Hidetoshi Yamashita Tomohiro Ikeda Tatsuya Mimura Shuichiro Eguchi Sadao Hori | 2003 | Ophthalmology2003，，9： | 2 |
| 13 | Increased levels of vascular endothelial growth factor and interleukin-6 in the aqueous humor of diabetics with macular edema显示文摘 | Hideharu Funatsu Hidetoshi Yamashita Hidetaka Noma Tatsuya Mimura Tetsuji Yamashita Sadao Hori | 2002 | American Journal of Ophthalmology2002，，1： | 2 |
| 14 | Experimental study on the ultimate strength of steel arches显示文摘 | Sakimoto Tatsuro Yamao Toshitaka Komatsu sadao | 1979 | Proceeding of the Japan Society of Civil Engineers1979，，286： | 1 |
| 15 | Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease显示文摘 | Teiko Kimpara A. Takeda Koichi Watanabe Yasuto Itoyama Shuntaro Ikawa Minro Watanabe Hiroyuki Arai Hidetada Sasaki Susumu Higuchi Naoshi Okita Sadao Takase Hiroshi Saito Kazuhiro Takahashi Shigeki Shibahara | 1997 | Human Genetics1997，，1： | 1 |
| 16 | Assessment of voiding dysfunction in Parkinson's disease by the international prostate symptom score显示文摘 | Isao A Sadao K | 2000 | J Neurol Neurosurg Psychiatry2000，68，： | 1 |
| 17 | Simultaneous determination of 64 pesticides in fiver water by stir bar sorptive extraction and thermal desorption-gas chromatography-mass spectrometry显示文摘 | Sadao N Shigeki D | 2005 | Analytical and Bioanalytical Chemistry2005，382，1： | 1 |
| 18 | Simultaneous determination of 22 volatile organic compounds, methyl -tert-butyl ether, 1, 4-dioxane, 2-methylisoborneol and geosmin in water by headspace solid phase microextraction-gas 显示文摘 | Sadao Nakamura Shigeki Daishima | 2005 | Analytica Chimica Acta2005，548，： | 1 |
| 19 | The effect of feeding stimulant indiedon digestive enzymes in carp intestine显示文摘 | Kenji takil Sadao Shimeno | 1986 | Bull Japan Soc ScienceFish1986，52，8： | 1 |
| 20 | Enzymatic enrichment of astaxanthin from Haematococcus pluvialis cell extracts显示文摘 | Toshihiro Nagao Tadashi Fukami Yoshiharu Horita Sadao Komemushi Akio Sugihara Yuji Shimada | 2003 | Journal of the American Oil Chemists’ Society2003，，10： | 1 |
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