|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Chronic obstructive pulmonary disease as a risk factor for lung cancer显示文摘The association between chronic obstructive pulmonary disease(COPD) and lung cancer has long been a subject of intense debate. The high prevalence of COPD in elderly smokers inevitably strengthens their coincidence. In addition to this contingent coincidence, recent studies have revealed a close association between the two diseases that is independent of the smoking history; that is, the existence of COPD is an independent risk factor for the development of lung cancer. Molecular-based evidence has been accumulating as a result of the efforts to explain the underlying mechanisms of this association. These mechanisms may include the following: the retention of airborne carcinogens followed by the activation of oncogenes and the suppression of tumor suppressor genes; the complex molecular mechanism associated with chronic inflammation in the distal airways of patients with COPD; the possible in-volvement of putative distal airway stem cells; and gel netic factors that are common to both COPD and lung cancer. The existence of COPD in patients with lung l cancer may potentially affect the process of diagnosis, surgical resection, radiotherapy, chemotherapy, and end-of-life care. The comprehensive management of COPD is extremely important for the appropriate treatment of lung cancer. Surgical resections with the aid of early interventions for COPD are often possible, even for patients with mild-to-moderate COPD. New challenges, such as lung cancer CT screening for individuals t at high risk, are now in the process of being implemented. Evaluating the risk of lung cancer in patients with COPD may be warranted in community-based lung cancer screening. | Yuichi Takiguchi Ikuo Sekine Shunichiro Iwasawa Ryota Kurimoto Koichiro Tatsumi | 2014 | World Journal of Clinical Oncology2014，5，4： | 21 |
| 2 | Different effects of ghrelin, des-acyl ghrelin and obestatin on gastroduodenal motility in conscious rats显示文摘Three peptides, ghrelin, des-acyl ghrelin and obestatin are derived from a common prohormone, preproghrelin by posttranslational processing, originating from endocrine cells in the stomach. To examine the effects of these peptides, we applied the manometric measurement of gastrointestinal motility in freely moving conscious rat models. Ghrelin exerts stimulatory effects on the motility of antrum and duodenum in both fed and fasted state of animals. Des-acyl ghrelin exerts inhibitory effects on the motility of antrum, but not on the motility of duodenum in the fasted state of animals. Obestatin exerts inhibitory effects on the motility of antrum and duodenum in the fed state, but not in the fasted state of animals. NPY Y2 or Y4 receptors in the brain may mediate the action of ghrelin, CRF type 2 receptors in the brain mediate the action of des-acy ghrelin, whereas CRF type 1 and type 2 receptors in the brain mediate the action of obestatin. Vagal afferent pathways might be involved in the action of ghrelin, but not involved in the action of des-acyl ghrelin, whereas vagal afferent pathways might be partially involved in the action of obestatin. | Mineko Fujimiya Akihiro Asakawa Koji Ataka Ikuo Kato Akio Inui | 2008 | World Journal of Gastroenterology2008，14，41： | 12 |
| 3 | Hepatic steatosis as a possible risk factor for the development of hepatocellular carcinoma after eradication of hepatitis C virus with antiviral therapy in patients with chronic hepatitis C显示文摘AIM: To elucidate risk factors contributing to the development of hepatocellular carcinoma (HCC) among patients with sustained viral response (SVR) after interferon (IFN) treatment and to examine whether HCV-RNA still remained in the liver of SVR patients who developed HCC. METHODS: Two-hundred and sixty-six patients, who achieved SVR, were enrolled in this study. We retrospectively reviewed clinical, viral and histological features of the patients, and examined whether the development of HCC depends on several clinical variables using Kaplan-Meier Method. RT-PCR was used to seek HCV-RNA in 3 out of 7 patients in whom liver tissue was available for molecular analysis. RESULTS: Among the enrolled 266 patients with SVR, HCC developed in 7 patients (7/266; 2.6%). We failed to detect HCV-RNA both in cancer and non-cancerous liver tissue in all three patients. The cumulative incidence for HCC was significantly different depending on hepatic fibrosis (F3-4) (P = 0.0028), hepatic steatosis (Grade 2-3) (P = 0.0002) and age (≥ 55) (P = 0.021) at the pre-interferon treatment. CONCLUSION: The current study demonstrated that age, hepatic fibrosis, and hepatic steatosis at pre- interferon treatment might be risk factors for developing HCC after SVR. | Atsushi Tanaka Satoko Uegaki Hiroko Kurihara Kiyoshi Aida Masaki Mikami Ikuo Nagashima Junji Shiga Hajime Takikawa | 2007 | World Journal of Gastroenterology2007，13，39： | 12 |
| 4 | Genetic and epigenetic risks of intracytoplasmic sperm injection method显示文摘怀孕由帮助繁殖技术完成了,特别地由胞质内精子注射(ICSI ) 过程,产生对与 ICSI 对待的男人口固有的基因风险和对这个创新过程固有的另外的风险。记录,以及理论,风险在现在的评论学习被讨论。这些风险主要表示位于男性下面的基因畸形的后果代替生育力(或不孕) 并且可能在不孕的治疗为新奇途径和应用的发展成为激发器。另外,冒的风险,当先天的异例和另外的理论或随机的风险被讨论,一个复合基因背景出现在出生。最近的数据建议那种帮助繁殖技术可能也影响雄配子,雌配子,或力量的渐成说特征影响早胚胎开始。它可能也为印畸形的 genomic 与增加的风险被联系。 | Ioannis Georgiou Maria Syrrou Nicolaos Pardalidis Konstantinos Karakitsios Themis Mantzavinos Nikolaos Giotitsas Dimitrios Loutradis Fotis Dimitriadis Motoaki Saito Ikuo Miyagawa Pavlos Tzoumis Anastasios Sylakos Nikolaos Kanakas Theodoros Moustakareas Dimitrios Baltogiannis Stavros Touloupides Dimitrios Giannakis Michael Fatouros Nikolaos Sofikitis | 2006 | Asian Journal of Andrology2006，8，6： | 9 |
| 5 | Histological diagnosis of gastric submucosal tumors: A pilot study of endoscopic ultrasonography-guided fine-needle aspiration biopsy vs mucosal cutting biopsy显示文摘AIM: To compare the usefulness of endoscopic ultrasonography-guided fine-needle aspiration biopsy(EUS-FNAB) without cytology and mucosal cutting biopsy(MCB) in the histological diagnosis of gastric submucosal tumor(SMT).METHODS: We prospectively compared the diagnostic yield, feasibility, and safety of EUS-FNAB and those of MCB based on endoscopic submucosal dissection. The cases of 20 consecutive patients with gastric SMT ≥1 cm in diameter. who underwent both EUS-FNAB and MCB were investigated.RESULTS: The histological diagnoses were gastrointestinal stromal tumors(n = 7), leiomyoma(n =6), schwannoma(n = 2), aberrant pancreas(n = 2), and one case each of glomus tumor, metastatic hepatocellular carcinoma, and no-diagnosis. The tumors' mean size was 23.6 mm. Histological diagnosis was made in 65.0% of the EUS-FNABs and 60.0% of the MCBs, a nonsignificant difference. There were no significant differences in the diagnostic yield concerning the tumor location or tumor size between the two methods. However, diagnostic specimens were significantly more frequently obtained in lesions with intraluminal growth than in those with extraluminal growth by the MCB method(P = 0.01). All four SMTs with extraluminal growth were diagnosed only by EUSFNAB(P = 0.03). No complications were found in either method.CONCLUSION: MCB may be chosen as an alternative diagnostic modality in tumors showing the intraluminal growth pattern regardless of tumor size, whereas EUSFNAB should be performed for SMTs with extraluminal growth. | Hisatomo Ikehara Zhaoliang Li Jiro Watari Masato Taki Tomohiro Ogawa Takahisa Yamasaki Takashi Kondo Fumihiko Toyoshima Tomoaki Kono Katsuyuki Tozawa Yoshio Ohda Toshihiko Tomita Tadayuki Oshima Hirokazu Fukui Ikuo Matsuda Seiichi Hirota Hiroto Miwa | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，14： | 7 |
| 6 | Impairment of innate immune responses in cirrhotic patients and treatment by branched-chain amino acids显示文摘It has been reported that host defense responses,such as phagocytic function of neutrophils and natural killer(NK)cell activity of lymphocytes,are impaired in cirrhotic patients.This review will concentrate on the impairment of innate immune responses in decompensated cirrhotic patients and the effect of the treatment by branched-chain amino acids(BCAA)on innate immune responses.We already reported that phagocytic function of neutrophils was significantly improved by3-mo BCAA supplementation.In addition,the changes of NK activity were also significant at 3 mo of supplementation compared with before supplementation.Also,Fisher’s ratios were reported to be significantly increased at 3 mo of BCAA supplementation compared with those before oral supplementation.Therefore,administration of BCAA could reduce the risk of bacterial and viral infection in patients with decompensated cirrhosis by restoring impaired innate immune responses of the host.In addition,it was also revealed that BCAA oral supplementation could reduce the risk of development of hepatocellular carcinoma in cirrhotic patients.The mechanisms of the effects will also be discussed in this review article. | Ikuo Nakamura | 2014 | World Journal of Gastroenterology2014，20，23： | 7 |
| 7 | Exposure to polycyclic aromatic hydrocarbons with special focus on cancer显示文摘Polycyclie aromatic hydrocarbons(PAHs) are a group of compounds consisting of two or more fused aromatic rings.Most of them are formed during incomplete combustion of organic materials such as wood and fossil fuels,petroleum products,and coal.The composition of PAH mixtures varies with the source and is also affected by selective weathering effects in the environment.PAHs are ubiquitous pollutants frequently found in a variety of environments such as fresh water and marine sediments,the atmosphere,and ice.Due to their widespread distribution,the environmental pollution due to PAHs has aroused global concern.Many PAHs and their epoxides are highly toxic,mutagenic and/or carcinogenic to microorganisms as well as to higher forms of life including humans.The main aim of this review is to provide contemporary information on PAH sources,route of exposure,worldwide emission rate,and adverse effects on humans,especially with reference to cancer. | Thamaraiselvan Rengarajan Peramaiyan Rajendran Natarajan Nandakumar Boopathy Lokeshkumar Palaniswami Rajendran Ikuo Nishigaki | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，3： | 6 |
| 8 | Advances in diagnostic testing for gastroesophageal reflux disease显示文摘Gastroesophageal reflux disease (GERD) contributes substantially to morbidity and to costs in the United States health care system. The burden of this disease has resulted in attempts at improving diagnosis and characterizing patients. Numerous research and technical advances have enhanced our understanding of both the utility and limitations of a variety of diagnostic modalities. The purpose of this review is to highlight recent advances in GERD diagnostic testing and to discuss their implications for use in clinical practice. Topics addressed include esophageal pH monitoring, impedance testing, symptom association analyses, narrow-band imaging, and histopathology. | Andrew J Gawron Ikuo Hirano | 2010 | World Journal of Gastroenterology2010，16，30： | 6 |
| 9 | Non-exposed endoscopic wall-inversion surgery as a novel partial gastrectomy technique显示文摘 | Takashi Mitsui Keiko Niimi Hiroharu Yamashita Osamu Goto Susumu Aikou Fumihiko Hatao Ikuo Wada Nobuyuki Shimizu Mitsuhiro Fujishiro Kazuhiko Koike Yasuyuki Seto | 2014 | Gastric Cancer2014，，3： | 5 |
| 10 | Proposal of criteria to select candidates with colorectal liver metastases for hepatic resection:Comparison of our scoring system to the positive number of risk factors显示文摘AIM: To select accurately good candidates of hepatic resection for colorectal liver metastasis. METHODS: Thirteen clinicopathological features, which were recognized only before or during surgery, were selected retrospectively in 81 consecutive patients in one hospital (GroupⅠ). These features were entered into a multivariate analysis to determine independent and significant variables affecting long-term prognosis after hepatectomy. Using selected variables, we created a scoring formula to classify patients with colorectal liver metastases to select good candidates for hepatic resection. The usefulness of the new scoring system was examined in a series of 92 patients from another hospital (Group Ⅱ), comparing the number of selected variables. RESULTS: Among 81 patients of GroupⅠ, multivariate analysis, i.e. Cox regression analysis, showed that multiple tumors, the largest tumor greater than 5 cm in diameter, and resectable extrahepatic metastases were significant and independent prognostic factors for poor survival after hepatectomy (P < 0.05). In addition, these three factors: serosa invasion, local lymph node metastases of primary cancers, and post- operative disease free interval less than 1 year including synchronous hepatic metastasis, were not significant, however, they were selected by a stepwise method of Cox regression analysis (0.05 < P < 0.20). Using these six variables, we created a new scoring formula to classify patients with colorectal liver metastases. Finally, our new scoring system not only classified patients in GroupⅠvery well, but also that in Group Ⅱ, according to long-term outcomes after hepatic resection. The positive number of these six variables also classified them well.CONCLUSION: Both, our new scoring system and the positive number of significant prognostic factors are useful to classify patients with colorectal liver metastases in the preoperative selection of good candidates for hepatic resection. | Ikuo Nagashima Tadahiro Takada Miki Adachi Hirokazu Nagawa Tetsuichiro Muto Kota Okinaga | 2006 | World Journal of Gastroenterology2006，12，39： | 5 |
| 11 | Risk factors for the development of post-endoscopic retrograde cholangiopancreatography pancreatitis in patients with asymptomatic common bile duct stones显示文摘BACKGROUND Previous studies have revealed that patients with asymptomatic common bile duct(CBD)stones are at a high risk of developing post-endoscopic retrograde cholangiopancreatography(ERCP)pancreatitis(PEP).However,no studies to date have addressed the risk factors for PEP in patients with asymptomatic CBD stones.AIM To examine the risk factors for PEP in patients with asymptomatic CBD stones.METHODS Using medical records of three institutions in Japan for 6 years,we identified a total of 1135 patients with choledocholithiasis including 967 symptomatic patients and 168 asymptomatic patients with native papilla who underwent therapeutic ERCP.We performed univariate and multivariate analyses to examine the risk factors for PEP in the 168 patients with asymptomatic CBD stones.RESULTS The overall incidence rate of PEP in all the patients with during study period was 4.7%(53/1135).Of the 168 patients with asymptomatic CBD stones,24(14.3%)developed PEP.In univariate analysis,precut sphincterotomy(P=0.009)and biliary balloon sphincter dilation(P=0.043)were significant risk factors for PEP.In multivariate analysis,precut sphincterotomy(P=0.002,95%CI:2.2-27.8,odds ratio=7.7),biliary balloon sphincter dilation(P=0.015,95%CI:1.4-17.3,odds ratio=4.9),and trainee endoscopists(P=0.048,95%CI:1.01-8.1,odds ratio=2.9)were significant risk factors for PEP.CONCLUSION ERCP for asymptomatic CBD stones should be performed by experienced endoscopists.When performing precut sphincterotomy or biliary balloon sphincter dilation in patients with asymptomatic CBD stones,the placement of a prophylactic pancreatic stent is strongly recommended to prevent PEP. | Hirokazu Saito Tatsuyuki Kakuma Ikuo Matsushita | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，10： | 5 |
| 12 | Association of polymorphic alleles of CTLA4 with inflammatory bowel disease in the Japanese显示文摘AIM: To examine an association between the cytotoxic T-lymphocyte antigen 4 (CTLA4) gene that plays a role in downregulation of T-cell activation and inflammatory bowel disease consisting of ulcerative colitis (UC) and Crohn's disease (CD) in the Japanese.METHODS: We studied 108 patients with UC, 79 patients with CD, and 200 sex-matched healthy controls, with respect to three single nucleotide polymorphisms (SNPs)in CTLA4, such as C-318T in the promoter region, A+49G in exon 1 and G+6230A in the 3' untranslated region (3'-UTR) by a PCR-restriction fragment length polymorphism method, and to an (AT)n repeat polymorphism in 3'-UTR by fragment analysis with fluorescence-labeling on denaturing sequence gels. Frequency of alleles and genotypes and their distribution were compared statistically between patients and controls and among subgroups of patients, using χ2 and Fisher exact tests.RESULTS: The frequency of 'A/A' genotype at the G+6230A SNP site was statistically lower in UC patients than in controls (3.7% vs 11.0%, P= 0.047, odds ratio (OR) = 0.311). Moreover, the frequency of'G/G' genotype at the A+49G SNP site was significantly higher in CD patients with fistula (48.6%) than those without it (26.2%)(P = 0.0388, OR=2.67).CONCLUSION: The results suggest that CTLA4 located at 2q33 is a determinant of UC and responsible for fistula formation in CD in the Japanese. | Haruhisa Machida Kazuhiro Tsukamoto Chun-Yang Wen Yukiko Narumi Saburou Shikuwa Hajime Isomoto Fuminao Takeshima Yohei Mizuta Norio Niikawa Ikuo Murata Shigeru Kohno | 2005 | World Journal of Gastroenterology2005，11，27： | 4 |
| 13 | Anatomical adaptations of three species of Chinese xerophytes (Zygophyllaceae)显示文摘第二等的木部特征和水平变化在三 xerophytic 种被描述, Zygophyllum xanthoxylon, Nitraria tangutorum,到西方的中国的蒺藜科土著人的 Tetraena 蒙古人集成通信适配器。所有种类让明显的生长除了,包围边界在 T 有时不连续。蒙古人集成通信适配器和 Z xanthoxylum 戒指到 semi-ring-porosity;简单穿孔板;轮流出现内部容器 pitting;非有中隔的纤维;帕拉气管的汇合的轴的实质;螺旋状的变厚和异种细胞的光线。然而,容器安排和容器的量的特征是不同的。容器元素趋于在 T 更短、更狭窄、更经常。蒙古人集成通信适配器能比在几乎不是不同的另外的二种导致更大的传导性的安全。沿着光线的方向的容器元素长度和纤维长度的变化显示出不规则的趋势。在两纤维长度和容器元素长度在树之中和在内树有重要差别。而且,在到荒芜的环境的解剖特征和适应性之间的关系也被讨论。 | YANG Shu-min FURUKAWA Ikuo | 2006 | Journal of Forestry Research2006，17，3： | 4 |
| 14 | The tumor microenvironment in hepatocellular carcinoma: Current status and therapeutic targets显示文摘 | Ju Dong Yang Ikuo Nakamura Lewis R. Roberts | 2010 | Seminars in Cancer Biology2010，，1： | 4 |
| 15 | 嗜酸性粒细胞性胃肠炎的生物治疗显示文摘生物单抗制剂可特异性地作用于免疫通路上的靶点,其在嗜酸性粒细胞性胃肠炎方面的基础研究和临床应用引起了学界的广泛关注。临床上发现,一部分嗜酸性粒细胞性食管炎患者对于局部糖皮质激素和变应原排除饮食治疗反应欠佳。另外,临床也在评估长期使用糖皮质激素相关的潜在风险。采用生物制剂进行全身治疗作为一种多维治疗方案,能减少局部药物治疗及变应原排除治疗的压力,为临床提供获益。新型生物制剂方案的认证工作正在进行中,量表和疾病活动度预后评估的验证研究在疗效评估方面至关重要,作用于IL-13通路的生物制剂已经在嗜酸性粒细胞性食管炎中显示出广阔前景。 | Joshua B. Wechsler Ikuo Hirano 柏小寅(翻译) 钱家鸣(审校) | 2018 | 中华临床免疫和变态反应杂志2018，12，4： | 4 |
| 16 | Wind characteristics of a strong typhoon显示文摘 | Shuyang Cao Yukio Tamura Naoshi Kikuchi Mamoru Saito Ikuo Nakayama Yutaka Matsuzaki | 2008 | Journal of Wind Engineering & Industrial Aerodynamics2008，，1： | 3 |
| 17 | Eosinophilic esophagitis: Updated consensus recommendations for children and adults显示文摘 | Chris A. Liacouras Glenn T. Furuta Ikuo Hirano Dan Atkins Stephen E. Attwood Peter A. Bonis A. Wesley Burks Mirna Chehade Margaret H. Collins Evan S. Dellon Ranjan Dohil Gary W. Falk Nirmala Gonsalves Sandeep K. Gupta David A. Katzka Alfredo J. Lucendo Jo | 2011 | The Journal of Allergy and Clinical Immunology2011，，1： | 3 |
| 18 | Crohn's disease in Japanese is associated with a SNP-haplotype of N-acetyltransferase 2 gene显示文摘AIM: To investigate the frequency and distribution of N-acetyltransferase 2 (NAT2) and uridine 5′-diphosphate (UDP)-glucuronosyltransferase 1A7 (UGT1A7) genes in patients with ulcerative colitis (UC) and Crohn's disease (CD).METHODS: Frequencies and distributions of NAT2 and UGT1A7SNPs as well as their haplotypes were investigated in 95 patients with UC, 60 patients with CD, and 200gender-matched, unrelated, healthy, control volunteers by PCR-restriction fragment length polymorphism (RFLP),PCR-denaturing high-performance liquid chromatography (DHPLC), and direct DNA sequencing.RESULTS: Multiple logistic regression analysis revealed that the frequency of haplotype, NAT2*7B, significantly increased in CD patients, compared to that in controls (P= 0.0130, OR = 2.802, 95%CI = 1.243-6.316). However,there was no association between NAT2 haplotypes and UC, or between any UGT1A7haplotypes and inflammatory bowel disease (IBD).CONCLUSION: It is likely that the NAT2 gene is one of the determinants for CD in Japanese. Alternatively, a new CD determinant may exist in the 8p22 region, whereNAT2is located. | Haruhisa Machida Kazuhiro Tsukamoto Chun-Yang Wen Saburou Shikuwa Hajime Isomoto Yohei Mizuta Fuminao Takeshima Kunihiko Murase Naomichi Matsumoto Ikuo Murata Shigeru Kohno Chen-Yang Wen | 2005 | World Journal of Gastroenterology2005，11，31： | 3 |
| 19 | Scenario analysis for reduction of pollutant load discharged from a watershed by recycling of treated water for irrigation显示文摘A model in which a river model was layered on a distributed model (double-layered model) was developed to analyse the transport of water and pollutants (nitrogen,phosphorus,and BOD as organic matter) in watersheds and rivers.The model was applied to the watershed of Abragafuchi Lake,Japan,where serious water pollution has occurred over three decades,and the applicability of the model was demonstrated.Scenarios of recycling of sewage treated-water into agriculture to reduce pollutant load discharged into the lake were analysed.The results showed that irrigating paddy fields with the sewage-treated water could contribute to conserving water and reducing pollutant load,with reduction rate in BOD,nitrogen,and phosphorus ranging from 6%–36%,16%–46%,and 18%–51%,respectively.Particularly,the results indicated that,irrigating paddy fields with the treated water during non-cropping periods and the accompanying reduction in withdrawn water from the river were more effective in reducing pollutant loads discharged into the lake.Further study is required on the effect of recycled water on crop cultivation and soil conditions for safe implementation. | Eisaku Shiratani Yoshiyuki Munakata Ikuo Yoshinaga Tomijiro Kubota Koji Hamada Tadayoshi Hitomi | 2010 | Journal of Environmental Sciences2010，22，6： | 3 |
| 20 | Intramanchette transport during primate spermiogenesis: expression of dynein, myosin Va, motor recruiter myosin Va, VIIa-Rab27a/b interacting protein, and Rab27b in the manchette during human and monkey spermiogenesis显示文摘瞄准:显示出是否分子的马达达因在在一条微导管轨道,分子的马达肌浆球蛋白 Va,马达 recruiter 肌浆球蛋白 Va, VIIa-Rab27a/b 交往蛋白质(MyRIP ) ,和泡受体上,一条 F 肌动朊轨道上的 Rab27b 在包含 intramanchette 运输(IMT ) 的人和猴子精子形式期间是在场的。方法:Spermiogenic 房间与妨碍的精子缺乏和正常成年 cynomolgus 猴子(Macacafascieularis ) 从三个人被获得。Immunocytochemical 察觉和反向的抄写聚合酶链反应(RT-PCR ) 蛋白质的分析被执行。样品被轻显微镜分析。结果:用 RT-PCR,我们发现了那达因在,肌浆球蛋白 Va, MyRIP 和 Rab27b 在猴子睾丸被表示。,这些蛋白质对领局部性由免疫荧光出现,特别地在人和猴子精子形式期间。结论:我们推测在首领精子形式期间,填写基于微导管、基于肌动朊的泡的那些蛋白质搬运系统,这实际上是在领的现在并且可能可能涉及 intramanchette 运输。 | Shinichi Hayasaka Yukihiro Terada Kichiya Suzuki Haruo Murakawa Ikuo Tachibana Tadashi Sankai Takashi Murakami Nobuo Yaegashi Kunihiro Okamura | 2008 | Asian Journal of Andrology2008，10，4： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员