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| 1 | Analysis of inborn errors of metabolism: disease spectrum for expanded newborn screening in Hong Kong显示文摘氨基酸,器官的酸和丰满的酸氧化的新陈代谢(IEM ) 的古典先天的错误的背景数据大部分正在缺乏香港,在集体基于 spectrometry 的扩展新生儿为 IEM 屏蔽没被开始的地方。瞄准在香港评估近似发生,光谱和古典 IEM 的另外的特征的当前的学习,将在开发为实验室血浆氨基酸记录的本地 area.Methods 屏蔽节目的一个扩展新生儿重要,血浆 acylcarnitines 和尿从年 2005~2009 的器官的酸分析在为 IEM 提供生物化学、基因的诊断服务的三个地区性的化学病理实验室包括回顾地 reviewed.Resu 在香港的古典 IEM 的发生粗略地被估计每 1000live 出生每 4122 生活出生,或 0.243 个盒子是至少 1 个盒子。这发生类似于全球报导的那些,包括中国的大陆。hyperphenylalaninemia 的估计的发生在 29 542 实时 births.Conclusions 是 1 我们的数据显示它为在香港的扩展新生的屏蔽节目的介绍是无可争辩的。因为香港是一个大城市的城市,一个全面扩展新生的屏蔽程序和工作分派系统应该是可得到的服务在区域出生的出生不满一月的婴儿。 | Han-Chih Hencher Lee Chloe Miu Mak Ching-Wan Lam Yuet-Ping Yuen, Angel On-Kei Chan Chi-Chung Shek Tak-Shing Siu Chi-Kong Lai Chor-Kwan Ching Wai-Kwan Siu Sammy Pak-Lam Chen Chun-Yiu Law Morris Hok-Leung Tai Sidney Tam Albert Yan-Wo Chan | 2011 | Chinese Medical Journal2011，，7： | 12 |
| 2 | Single photon sources with single semiconductor quantum dots显示文摘在这贡献,我们简短记起量光学的基本概念和对有单个 QD 的单个光子的产生的物理的理解必要的半导体量点(QD ) 的性质。第一,我们象 QD 的光性质一样探讨量发射极洞系统,荧光和半导体 QD,和光子统计的光性质的理论。我们然后在以强壮的联合政体,效率, directionality,和极化完成他们的全面光性质和表演的限制光 microcavity 系统控制的量考察单个半导体 QD 的本地化。而且,我们将在单个光子来源的制造上讨论最近的进步,并且为嵌入的各种各样的途径挑选 QD 进 microcavities 或 photonic 水晶 nanocavities 并且显示出怎么扩大波长范围。我们特别地集中于在提高的温度操作导致高重复率,强壮的联合政体,和高收集效率的电子上驾驶的 QD 单个光子来源的新一代。而且,在强壮的联合政体的房间温度单身者光子排放的新开发被考察。为实际单个光子的来源的难区分的光子和留下的挑战的产生也被讨论。 | Guang-Cun Shant Zhang-Qi Yin Chan Hung Shek Wei Huang | 2014 | Frontiers of physics2014，9，2： | 9 |
| 3 | 婴儿常见胃肠道症状的实用处理法则(一)显示文摘在婴儿,特别是配方奶喂养的婴儿中功能性胃肠道(GI)症状较为常见[1]。应对这一问题,儿科医师常采用更换配方奶的方式来处理。由于治疗婴儿功能性GI症状的双盲的、安慰剂对照的、前瞻性干预的试验非常有限,本文在世界各地儿童胃肠病专科医师和过敏症专科医师一致意见的基础上,制定了婴儿常见GI的实用处理法则,并具体介绍各种婴幼儿. | Yvan Vandenplas Pedro Gutierrez-Castrellon Carlos Velasco-Benitez Jorge Palacios Domingo Jaen Hugo Ribeiro Lynette Pei-Chi Shek Bee-Wah Lee Pedro Alarcon | 2013 | 临床儿科杂志2013，31，7： | 3 |
| 4 | Effect of Electropulsing on Recrystallization and Mechanical Properties of Silicon Steel Strips显示文摘Electropulsing-induced recrystallization and its effect on mechanical properties of oriented silicon steel strips (Fe-3.0%Si) were studied by optical microscopy, scanning electron microscopy and electron back-scatter diffraction. The results indicated that electropulsing accelerated recrystallization, and decreased the temperature of recrystallization. Electropulsing favors refinement of the grain structure of the alloy. Effects of electropulsing on strength and elongation of the alloy were discussed from the point view of dislocation dynamics, microstructural changes, and electropulsing kinetics. | Guoliang Hu Yaohua Zhu Guoyi Tang Chanhung Shek Iianan Liu | 2011 | Journal of Materials Science & Technology2011，27，11： | 3 |
| 5 | SIGMAPLUG—A NEW TEMPERATURE INDICATOR FOR REMAINING LIFE ASSESSMENT OF HIGH TEMPERATURE COMPONENTS显示文摘1.IntroductionItisgeneralyacceptedthattheeficiencyandreliabilityofpowerplantsareofparamountimportanceinsupportingthegrowthoft... | J.K.L. Lai, C.H. Shek and K.W. Wong Department of Physics and Materials Science, City University of Hong Kong, 27887808, China | 1999 | Acta Metallurgica Sinica(English Letters)1999，12，1： | 2 |
| 6 | Expression of Transforming Growth Factor-β1 by Pancreatic Stellate Cells and Its Implications for Matrix Secretion and Turnover in Chronic Pancreatitis显示文摘 | Fanny Wai-Tsing Shek Robert Christopher Benyon Fiona Mairi Walker Peter Raymond McCrudden Sylvia Lin Foon Pender Elizabeth Jean Williams Penelope Ann Johnson Colin David Johnson Adrian Calvin Bateman David Roger Fine John Peter Iredale | 2002 | The American Journal of Pathology2002，，5： | 2 |
| 7 | Pharmacogenetics of anticancer monoclonal antibodies显示文摘Pharmacogenetics is the study of therapeutic and adverse responses to drugs based on an individual’s genetic background.Monoclonal antibodies(mAbs)are a rapidly evolving field in cancer therapy,however a number of newly developed and highly effective mAbs(e.g.,anti-CTLA-4 and anti-PD-1)possess pharmacogenomic profiles that remain largely undefined.Since the first chemotherapeutic mAb Rituximab was approved in 1997 by the US Food and Drug Administration for cancer treatment,a broad number of other mAbs have been successfully developed and implemented into oncological practice.Nowadays,mAbs are considered as one of the most promising new approaches for cancer treatment.The efficacy of mAb treatment can however be significantly affected by genetic background,where genes responsible for antibody presentation and metabolism,for example,can seriously affect patient outcome.This review will focus on current anticancer mAb treatments,patient genetics that shape their efficacy,and the molecular pathways that bridge the two. | Dmitrii Shek Scott ARead Golo Ahlenstiel Irina Piatkov | 2019 | Cancer Drug Resistance2019，2，1： | 2 |
| 8 | The effect of pregnancy on hiatal dimensions and urethral mobility: an observational study显示文摘 | Ka Lai Shek Jenny Kruger Hans Peter Dietz | 2012 | International Urogynecology Journal2012，，11： | 2 |
| 9 | Diagnostic accuracy of Focused Abdominal Sonography for Trauma in blunt abdominal trauma patients in a trauma centre of Hong Kong显示文摘为损伤的 ObjectiveFocused 腹的 Sonography (快) 广泛地为 intraperitoneal 的察觉被使用在受不了钝腹的损伤(蝙蝠) 的病人的免费液体。针对在指明的损伤 centre.MethodsThis 估计这调查的诊断精确性的这研究是在在香港在一个损伤中心看见的 6 年时期上的蝙蝠病人的回顾的研究。快调查结果与剖腹术,腹的计算断层摄影术或尸体调查结果相比,它为 intraperi-toneal 的存在用作标准答案免费液体。没快有的病人或确定的测试执行了,有先存在的腹液体,在复活死了或有快调查结果的 imcomplete 文档的标准答案被排除。性能当敏感,特性,预兆的值(PV ) ,可能性的比率(LR ) 和 accuracy.ResultsFAST 在 302 个病人被执行,他们中的 153 个在这分析被包括,快被表示。敏感,特性,积极 PV,否定 PV,积极 LR,否定 LR 和精确性为快分别地 50.0% , 97.3% , 87.0% , 84.6% , 18.8, 0.5 和 85.0% 。快被发现在不太严重地受伤的病人和在更严重地受伤的 patients.ConclusionFAST 特定的更多更敏感是在对蝙蝠病人的起始的评价的可靠调查。诊断价值能被损害的严厉快影响,职员训练被需要进一步提高它的有效使用。 | Cheung Kent Shek Wong Hay Tai Leung Ling Pong Tsang Tat Chi Leung Gilberto Ka Kit | 2012 | Chinese Journal of Traumatology2012，15，5： | 2 |
| 10 | Imaging of peripheral PNET:common and uncommon locations显示文摘 | Khong PL Chan GCF Shek TWH | 2002 | Clin Radiol2002，57，4： | 1 |
| 11 | Inflammatory pseudotumor-like follicular dendritic cell tumor,a distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr vires association显示文摘 | Cheuk W Chan JK Shek TW | 2001 | Am J Surg Pathol2001，25，6： | 1 |
| 12 | Differences between fathers and mothers in the treatment of,and relationship with,their teenage children:Perceptions of Chinese adolescent显示文摘 | Shek D T L | 2000 | Adolescent2000，137，35： | 1 |
| 13 | Family functioning and psychological well-being, school adjustment, and problem behavior in Chinese adolescents with and without economic disadvantage显示文摘 | Shek D T L | 2002 | The Journal of Genetic Psychology2002，163，4： | 1 |
| 14 | Lipesomal antioxidants prolonged protection against acute respiratory distress syndrome显示文摘 | Fan J Shek PN Suntress ZE | 2000 | Surgery2000，128，2： | 1 |
| 15 | Incidence and Mortality of Generalized Convulsive Status Epilepticus in California显示文摘 | Wu Y W Shek D W Garcia P A | 2002 | Neurology2002，58，7： | 1 |
| 16 | Effect of electmpuls- ing treatment on nficrostructure and tensile fracture be- havior of aged Mg - 9A1 - 1Zn alloy strip 显示文摘 | Jiang Y Tang G Shek C Zhu Y | 2009 | Applied Physics A: Materials Science & Processing2009，97，3： | 1 |
| 17 | How can transforming growth factor beta be targeted usefully to combat liver fibrosis?显示文摘 | Shek FW Benyon RC | 2004 | EurJGastroenterolHepatol2004，16，2： | 1 |
| 18 | Ethnic differences in gengtic susceptibility to atopy and asthma in Singapore 显示文摘 | Shek LP Tay AH Goh DL | 2000 | Ann Acad Med Singapore2000，29，： | 1 |
| 19 | Effects of Exercise and Training on Natural Killer Cell Counts and Cytolytic Activity:A Metaanalysis显示文摘 | SHEPHERD R J SHEK P N | 1999 | Sports Med1999，28，3： | 1 |
| 20 | The immunomodulatory effects of hypcrtonic saline resuscitation in patients sustaining traumatic hemorrhagic shock: a randomized, controlled, double-blinded trial显示文摘 | RIZOLI SB RHIND SG SHEK PN | 2006 | Ann Surg2006，243，1： | 1 |
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