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| 1 | Fecal lactoferrin accurately reflects mucosal inflammation in inflammatory bowel disease显示文摘BACKGROUND Studies have demonstrated a potential role for fecal biomarkers such as fecal calprotectin(FC)and fecal lactoferrin(FL)in monitoring inflammatory bowel diseases(IBD)-Crohn's disease(CD)and ulcerative colitis(UC).However,their correlation to endoscopic scores,disease severity and affected intestinal surface has not been extensively investigated.AIM To correlate FL,and for comparison white blood cell(WBC)and C-reactive protein(CRP),with endoscopic scores,disease extent and location in CD and UC.METHODS Retrospective analysis in 188 patients who had FL,CRP and WBC determined within 30 d of endoscopy.Disease location,disease extent(number of intestinal segments involved),disease severity(determined by endoscopic scores),timing of FL testing in relation to colonoscopy,as well as the use of effective fast acting medications(steroids and biologics)between colonoscopy and FL measurement,were recorded.RESULTS In 131 CD and 57 UC patients,both CRP and FL-but not WBC-distinguished disease severity(inactive,mild,moderate,severe).In patients receiving fastacting(steroids or biologics)treatment in between FL and colonoscopy,FL showed a higher correlation to endoscopic scores when tested before vs after the procedure(r=0.596,P<0.001,vs r=0.285,P=0.15 for the Simple Endoscopic Score for CD;and r=0.402,P=0.01 vs r=0.054 P=0.84 for Disease Activity Index).Finally,FL was significantly correlated with the diseased mucosal surface(colon-ileocolon>small bowel)and the number of inflamed colon segments.CONCLUSION FL and CRP separated disease severity categories with FL showing lower discriminating P-values.FL showed a close correlation with the involved mucosal surface and with disease extent and was more closely correlated to endoscopy when determined before the procedure–this indicating that inflammatory activity changes associated with therapy might be rapidly reflected by FL levels.FL can accurately and timely characterize intestinal inflammation in IBD. | Marrieth G Rubio Kofi Amo-Mensah James M Gray Vu Q Nguyen Sam Nakat Douglas Grider Kim Love James H Boone Dario Sorrentino | 2019 | World Journal of Gastrointestinal Pathophysiology2019，10，5： | 4 |
| 2 | Prosthetic above-knee femoropopliteal bypass grafting: Five-year results of a randomized trial显示文摘 | Richard M Green William M Abbott Teruo Matsumoto Jock R Wheeler Normand Miller Frank J Veith Sam Money H Edward Garrett | 2000 | Journal of Vascular Surgery2000，，： | 2 |
| 3 | Carbonatites and Alkaline Igneous Rocks in Post-Collisional Settings:Storehouses of Rare Earth Elements显示文摘The rare earth elements(REE)are critical raw materials for much of modern technology,particularly renewable energy infrastructure and electric vehicles that are vital for the energy transition.Many of the world's largest REE deposits occur in alkaline rocks and carbonatites,which are found in intracontinental,rift-related settings,and also in syn-to post-collisional settings.Post-collisional settings host significant REE deposits,such as those of the Mianning-Dechang belt in China.This paper reviews REE mineralization in syn-to post-collisional alkaline-carbonatite complexes worldwide,in order to demonstrate some of the key physical and chemical features of these deposits.We use three examples,in Scotland,Namibia,and Turkey,to illustrate the structure of these systems.We review published geochemical data and use these to build up a broad model for the REE mineral system in post-collisional alkaline-carbonatite complexes.It is evident that immiscibility of carbonate-rich magmas and fluids plays an important part in generating mineralization in these settings,with REE,Ba and F partitioning into the carbonate-rich phase.The most significant REE mineralization in post-collisional alkaline-carbonatite complexes occurs in shallow-level,carbothermal or carbonatite intrusions,but deeper carbonatite bodies and associated alteration zones may also have REE enrichment. | Kathryn M.Goodenough Eimear A.Deady Charles D.Beard Sam Broom-Fendley Holly ALElliott Frederick van den Berg HüseyinÖztürk | 2021 | Journal of Earth Science2021，32，6： | 2 |
| 4 | Aflatoxin Exposure and Viral Hepatitis in the Etiology of Liver Cirrhosis in The Gambia, West Africa显示文摘 | Kuniholm Mark H Lesi Olufunmilayo A Mendy Maimuna Akano Aliu O Sam Omar Hall Andrew J Whittle Hilton Bah Ebrima Goedert James J Hainaut Pierre Kirk Gregory D | 2008 | Environmental Health Perspectives2008，，11： | 2 |
| 5 | Coaxial and waveguide microcalorimeters for RF and microwave power standards显示文摘 | Nak Sam Chung Joon Shin H Bayer R Honigbaum | 1989 | IEEE Trans1989，38，2： | 1 |
| 6 | A case for using plethodontid salamanders for monitoring biodiversity and ecosystem integrity of North American forests显示文摘 | WELSH J R SAM D | 2002 | Conserration Biology2002，15，： | 1 |
| 7 | A class of proportional in tegral sliding mode control with application to active suspension system显示文摘 | Sam Y M Osman H S Ghani M R | 2004 | Systems & Control Letters2004，51，3： | 1 |
| 8 | The measurement of velocity dispersion and frequency-dependent intrinsic attenuation in sedimentary rocks 显示文摘 | Sams M S Neep J P Worthington M H | 1997 | Geophysics1997，62，5： | 1 |
| 9 | Dynamics of a stochastic Lotka - Volterra model perturbed by white noise 显示文摘 | Du N H Sam V H | 2006 | J Math Anal Appl2006，324，： | 1 |
| 10 | Early results of a single-blinded, randomized, controlled, Internet-based multicenter trial comparing Prolene and Vypro?II mesh in Lichtenstein hernioplasty显示文摘 | Sven Bringman Timo-Jaakko Heikkinen Staffan Wollert Johanna ?sterberg Sam Smedberg H?kan Granlund Stig Ramel G?ran Fell?nder Bo Anderberg | 2004 | Hernia2004，，2： | 1 |
| 11 | Expression of brain derived neurotrophic factor, activity - regulated cytoskeleton protein mRNA, and enhancement of adult hippocampal neurogenesis in rats after sub - chronic and chronic treatment with the triple monoamine re - uptake inhibitor tesofensine 显示文摘 | Larsen MH Rosenbrock H Sams -Dodd F | 2007 | Eur J Pharmacol2007，555，23： | 1 |
| 12 | Magnesium science,technology and applications显示文摘 | Eliezer D Aghion E (SAM)Froes F H | 1998 | Advanced Performance Materials1998，5，： | 1 |
| 13 | The measurement of velocity dispersion and frequency dependent intrinsic attenuation in sedimentaryrocks 显示文摘 | Sams M S Neep J P Worthington M H | 1997 | Geophysics1997，62，5： | 1 |
| 14 | A comparison of option prices under different pricing measures in a stochastic volatility model with correlation 显示文摘 | VICKY H DAVID H SAM H | 2005 | Review of Derivativatives Research2005，，8： | 1 |
| 15 | MicroRNA evolution by arm switching显示文摘 | SAM GRIFFITHS-JONES JEROME H L HUI ANTONIO MARCO | 2011 | EMBO Reports2011，12，2： | 1 |
| 16 | Hydraulic conductance and water potential gradients in squash leaves showing mycorrhizainduced increases in stomatal conductance显示文摘 | AUGER M TOLER H D SAMS C E | 2008 | Mycorrhiza2008，，18： | 1 |
| 17 | The measurementof velocity dispersion and frequency-dependent intrinsic attenuationin sedimentary rocks显示文摘 | Sams M S Neep J P Worthington M H | 1997 | Geophysics1997，62，5： | 1 |
| 18 | Serum and Salivary IgA antibodies against a defined epitope of the Epstein-Barr virus nuclear Aantigen (EBNA)are elevated in nasopharyngeal Carcinoma显示文摘 | FOONG Y T CHENG H M SAM C K | 1990 | Int J Cancer1990，45，6： | 1 |
| 19 | Changes in lipid profiles of rats fed with seaweed-based diets显示文摘 | Wong K H Sam S W Cheung P C K | 1999 | Nutrition Research1999，19，10： | 1 |
| 20 | Reproducing the experimental pull-out and shear strength of clinched sheet metal connections using FEA 显示文摘 | Coppieters Sam Cooreman S Sol H et ol | 2010 | Int J Mater Form2010，41，： | 1 |
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