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| 1 | Meeting report:a hard look at the state of enamel research显示文摘The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines(ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research(NIDCR). Discussion topics included model organisms, stem cells/cell lines, and tissues/3 D cell culture/organoids. Scientists from a number of disciplines,representing institutions from across the United States, gathered to discuss advances in our understanding of enamel, as well as future directions for the field. | ophir d klein olivier duverger wendy shaw rodrigo s lacruz derk joester janet moradian-oldak megan k pugach j timothy wright sarah e millar ashok b kulkarni john d bartlett thomas gh diekwisch pamela den besten james p simmer | 2017 | International Journal of Oral Science2017，9，4： | 3 |
| 2 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 3 | Mathematical simulation of radial heat transfer in packed beds by pseudohomogeneous modeling显示文摘Uniform flow regime and constant effective thermal conductivity inside packed beds are commonly accepted in the evaluation of the fluid dynamics and heat transfer in such systems.However,several authors have confirmed the presence of an oscillatory velocity profile caused by the effective contribution of porosity profile in the fluid dynamic behavior of packed beds,which directly influences the heat transfer inside the beds.This paper describes the application of a pseudo-homogeneous mathematical model for describing heat transfer in packed beds with oscillatory profiles of velocity and porosity,using a radius-dependent model for effective thermal conductivity k r.Several temperature profiles were obtained in a packed bed system with thermal source located on the wall.The simulated temperature and effective thermal conductivity obtained from simulations were compared with experimental data and calculation from a model based on uniform k r fitting.The results indicate that the proposed mathematical modeling was capable of better representing the heat transfer in the packed bed. | Rodrigo Béttega Marcos Flávio Pinto Moreira Ronaldo Guimaraes Corrêa José Teixeira Freire | 2011 | Particuology2011，9，2： | 2 |
| 4 | Grain-size end-members and environmentally sensitive grain-size components: A comparative study in the mud shelf depocenters off southern Brazil显示文摘The current study aims to do a comparative analysis of the results obtained with two End-Member(EM)grain-size modeling techniques(AnalySize and BasEMMA)and the Environmental Sensitive Grain-Size(ESGS)modeling for sediment samples collected in the mudbelts of the southern Brazilian shelf.The methods were compared using grain-size data from the south Brazilian shelf,and the results are discussed here.It is the first time that the concept of ESGS,in its present form,is utilized outside China.The results show that despite its relative ease of use,the ESGS is not fully comparable to the EM analyses,and only two grain-size ESGS classes were recognized as analogous to EMs.The comparison of the AnalySize and BasEMMA procedures also revealed significant differences between the techniques.A comparative analysis between the two EM techniques revealed advantages in the BasEMMA,especially in the better correlation of the end-members with the original grain size distribution.The analysis of the geographical distribution of the EM abundances allowed point sources of sandy populations to be recognized as well as the contribution of the Rio de la Plata as a source of silty sediments to be inferred. | Michel Michaelovitch de Mahiques Samara Cazzoli y Goya Maria Carolina da Silva Nogueira de Matos Rodrigo Augusto Udenal de Oliveira Bianca Sung Mi Kim Paulo Alves de Lima Ferreira Rubens Cesar Lopes Figueira Marcia Caruso Bícego | 2021 | International Journal of Sediment Research2021，36，2： | 2 |
| 5 | Characterization and clinical impact of antinuclear antibodies in primary biliary cirrhosis显示文摘 | Paolo Muratori Luigi Muratori Rodolfo Ferrari Fabio Cassani Giampaolo Bianchi Marco Lenzi Luis Rodrigo Antonio Linares Dolores Fuentes Francesco B Bianchi | 2003 | The American Journal of Gastroenterology2003，，2： | 2 |
| 6 | Comparison of Radical Prostatectomy Techniques: Open, Laparoscopic and Robotic Assisted显示文摘 | Rodrigo F Burak T Rodrigo B | 2008 | Int Braz J Urol2008，34，3： | 1 |
| 7 | Mucinous colorectal adenocarcinoma: influence of mucin expression (Muc1, 2 and 5) on clinico-pathological features and prognosis显示文摘 | Rodrigo Oliva Perez Bárbara Helou Bresciani Cláudio Bresciani Igor Proscurshim Desiderio Kiss Joaquim Gama-Rodrigues Diego Daniel Pereira Viviane Rawet Ivan Cecconnello Angelita Habr-Gama | 2008 | International Journal of Colorectal Disease2008，，： | 1 |
| 8 | Alkaline proteinase from intestine of nile tilapia (Oreochromis Niloticus)显示文摘 | Ranilson S B Eduardo J F L Rodrigo B A | 2005 | Process Biochemistry2005，40，： | 1 |
| 9 | Dry sliding wear behaviour of ZE41A magnesium alloy 显示文摘 | LOPEZ A J RODRIGO P TORRES B RAMS J | 2011 | Wear2011，271，1112： | 1 |
| 10 | Effects of supercritical carbon dioxide on waste banana peels for heavy metal removal显示文摘 | Juliana Q A Rodrigo B R Diego T S | 2011 | The Journal of Supercritical Fluids2011，58，： | 1 |
| 11 | Effect of Low-level Laser ( Ga-AlAs 655 nm) on Skeletal Muscle Fatigue Induced by Electrical Stimulation in Rats 显示文摘 | ALVARO R B LOPES-MARTINS RODRIGO L M | 2006 | J Appl Physiol2006，101，7： | 1 |
| 12 | Hydrolysis of platelet-activating factor by human serum paraoxonase 显示文摘 | Rodrigo L Mackness B Durrington PN | 2001 | Biochem J2001，354，1： | 1 |
| 13 | Characterization of en- tomopathogenie nematodes and symbiotic baeteria active against Spodoptera frugiperda ( Lepidoptera : Noctuidae ) and contribution of bacterial urease to the insecticidal effect 显示文摘 | Juliana M S Marina S D Rodrigo L B | 2012 | Biological Control2012，63，： | 1 |
| 14 | How does financial reporting quality relate to investment efficiency 显示文摘 | Gary C B Gilles H Rodrigo S | 2009 | Journal of Ac- counting and Economics2009，48，7： | 1 |
| 15 | Microstructure and wear resistance of Al-SiC composites coatings on ZE41 magnesium alloy显示文摘 | RODRIGO P CAMPO M TORRES B | 2009 | Applied Surface Science2009，255，22： | 1 |
| 16 | Evaluation of peripheral nerve regeneration by nerve growth factor locally administered with a novel system 显示文摘 | Santos X Rodrigo J Hontanilla B | 1998 | J Neurosci Methods1998，85，1： | 1 |
| 17 | Cyclin/PCNA is the auxiliary protein ofDNA polymerase-δ显示文摘 | Rodrigo B Rainer F Patricia A | 1987 | Nature1987，326，： | 1 |
| 18 | Performance evaluation of collision-reaction interface and internal standardization in quadrupole ICP-MS measurements 显示文摘 | Rodrigo F S S Marcelo B B G Edenir R P | 2011 | Talanta2011，86，： | 1 |
| 19 | Nonlinear multivariate analysis of neurophysiological signals 显示文摘 | ERNESTO P RODRIGO Q Q JOYDEEP B | 2005 | Progress in Neurobiology2005，77，1： | 1 |
| 20 | An economic assessment of proteins recovery from fish meal effluents by uhrafiltration显示文摘 | Marai D A Javier F Rodrigo B | 2004 | Trends in Food Science & Technology2004，15，10： | 1 |
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