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| 1 | Advances in alcoholic liver disease:An update on alcoholic hepatitis显示文摘Alcoholic hepatitis is a pro-inflammatory chronic liver disease that is associated with high short-term morbidity and mortality(25%-35% in one month) in the setting of chronic alcohol use. Histopathology is notable for micro- and macrovesicular steatosis, acute inflammation with neutrophil infiltration, hepatocellular necrosis, perivenular and perisinusoidal fibrosis, and Mallory hyaline bodies found in ballooned hepatocytes. Other findings include the characteristic eosinophilic fibrillar material(Mallory's hyaline bodies) found in ballooned hepatocytes. The presence of focal intense lobular infiltration of neutrophils is what typically distinguishes alcoholic hepatitis from other forms of hepatitis, in which the inflammatory infiltrate is primarily composed of mononuclear cells. Management consists of a multidisciplinary approach including alcohol cessation, fluid and electrolyte correction, treatment of alcohol withdrawal, and pharmacological therapy based on the severity of the disease. Pharmacological treatment for severe alcoholic hepatitis, as defined by Maddrey's discriminant factor ≥ 32, consists of either prednisolone or pentoxifylline for a period of four weeks. The body of evidence for corticosteroids has been greater than pentoxifylline, although there are higher risks of complications. Recently head-to-head trials between corticosteroids and pentoxifylline have been performed, which again suggests that corticosteroids should strongly be considered over pentoxifylline. | Randy Liang Andy Liu Ryan B Perumpail Robert J Wong Aijaz Ahmed | 2015 | World Journal of Gastroenterology2015，21，42： | 5 |
| 2 | Molecular basis of aggression显示文摘 | Randy J Nelson Silvana Chiavegatto | 2001 | Trends in Neurosciences2001，，12： | 2 |
| 3 | Resistance distance 显示文摘 | KLEIN D J RANDI G M | 1993 | Journal of Mathematical Chemistry1993，12，： | 1 |
| 4 | Extraversion, Neuroticism, and sus- ceptibility to positive and negative affect : a test of two theo- retical models 显示文摘 | Cheryl L R Randy J L | 1997 | Personality and Individual Differences1997，22，5： | 1 |
| 5 | Carbon and nitrogen dynamics in a forest soil amended with purified tannins from different plant species显示文摘 | Tamara E C K Robert J Z Randy A D | 2004 | Soil Biol Biochem2004，36，2： | 1 |
| 6 | Uroguanylin: how the gut got another satiety hormone显示文摘 | Seeley Randy J Tsch?p Matthias H | 2011 | Journal of Clinical Investigation2011，，9： | 1 |
| 7 | Subsurface damage in some single crystalline optical materials显示文摘 | RANDI J A LAMBROPOULOS J C JACOBS S D | 2005 | Applied Optics2005，44，12： | 1 |
| 8 | Aerial color infrared photography for determining late season nitrogen requirements in corn显示文摘 | Sripada R P Tteiniger R W White J G Randy W | 2005 | Agronomy Journal2005，97，： | 1 |
| 9 | Sex ratio and the infectionprocess in entomopathogenic nematodes :are males the colonizir^sex显示文摘 | Robin J S Moeen A H Randy G | 1998 | Journal of Invertebrate Pathology1998，72，： | 1 |
| 10 | Soot nanostructure: dependence upon synthesis conditions显示文摘 | Randy L Vander Wal Aaron J Tomasek | 2003 | Combustion and Flame2003，，1： | 1 |
| 11 | Exploring process data with the use of robust outlier detection algorithms显示文摘 | LEO H C RANDY J P MARY B S | 2003 | Journal of Process Control2003，，13： | 1 |
| 12 | Same city-different options:An analysis of the work trips of married couples in the metropolitan area of Oslo显示文摘 | Randi J | 2000 | Journal of Transport Geography2000，8，3： | 1 |
| 13 | Aerial color infrared photography for determining late season nitrogen requirements in corn 显示文摘 | Srlpada R P Tteiniger R W White J G Randy W | 2005 | Agronomy Journal2005，97，： | 1 |
| 14 | Molecular basis of aggression显示文摘 | Randy J Nelson Silvana Chiavegatto | 2001 | Trends in Neurosciences2001，，12： | 1 |
| 15 | Unique graphical representation of protein sequences based on nucleotide triplet codons显示文摘 | Randie M Zupan J Balaban A T | 2004 | Chem Phys Lett2004，397，12： | 1 |
| 16 | Test-retest study of fMRI signal change evoked by electroacupuncture stimulation显示文摘 | Jian Kong Randy L Gollub J | 2007 | NeuroImage2007，34，3： | 1 |
| 17 | Subsurface damage in some single crystalline optical materials显示文摘 | J A Randi J C Lambropoulos S D Jacobs | 2005 | Appl Opt2005，44，12： | 1 |
| 18 | A view of cloud computing显示文摘 | MICHAEL A ARMANDO F REAN Q ANTHONY D J RANDY K ANDY K GUNHO L DAVID P ARIEL R ION S MATEI Z | 2010 | Communications of the ACM2010，53，4： | 1 |
| 19 | Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes显示文摘 | Monique Gannagé Dorothee Dormann Randy Albrecht J?rn Dengjel Tania Torossi Patrick C. R?mer Monica Lee Till Strowig Frida Arrey Gina Conenello Marc Pypaert Jens Andersen Adolfo García-Sastre Christian Münz | 2009 | Cell Host & Microbe2009，，4： | 1 |
| 20 | Genetic algorithms combined with discriminant analysis for key variable identification显示文摘 | Leo Chiang Pell H Randy J | 2004 | J of Process Control2004，14，2： | 1 |
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