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| 1 | NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis显示文摘 | Eran Elinav Till Strowig Andrew L. Kau Jorge Henao-Mejia Christoph A. Thaiss Carmen J. Booth David R. Peaper John Bertin Stephanie C. Eisenbarth Jeffrey I. Gordon Richard A. Flavell | 2011 | Cell2011，，5： | 3 |
| 2 | The microbiota is dispensable for the early stages of peripheral regulatory T cell induction within mesenteric lymph nodes显示文摘Intestinal Foxp3+regulatory T cell(Treg)subsets are crucial players in tolerance to microbiota-derived and food-borne antigens,and compelling evidence suggests that the intestinal microbiota modulates their generation,functional specialization,and maintenance.Selected bacterial species and microbiota-derived metabolites,such as short-chain fatty acids(SCFAs),have been reported to promote Treg homeostasis in the intestinal lamina propria.Furthermore,gut-draining mesenteric lymph nodes(mLNs)are particularly efficient sites for the generation of peripherally induced Tregs(pTregs).Despite this knowledge,the direct role of the microbiota and their metabolites in the early stages of pTreg induction within mLNs is not fully elucidated.Here,using an adoptive transfer-based pTreg induction system,we demonstrate that neither transfer of a dysbiotic microbiota nor dietary SCFA supplementation modulated the pTreg induction capacity of mLNs.Even mice housed under germ-free(GF)conditions displayed equivalent pTreg induction within mLNs.Further molecular characterization of these de novo induced pTregs from mLNs by dissection of their transcriptomes and accessible chromatin regions revealed that the microbiota indeed has a limited impact and does not contribute to the initialization of the Treg-specific epigenetic landscape.Overall,our data suggest that the microbiota is dispensable for the early stages of pTreg induction within mLNs. | Carolin Wiechers Mangge Zou Eric Galvez Michael Beckstette Maria Ebel Till Strowig Jochen Huehn Joern Pezoldt | 2021 | Cellular & Molecular Immunology2021，18，5： | 2 |
| 3 | NK cells interactions with dendritic cells shape innate and adaptive immunity显示文摘 | Brilot F Strowig T Munz C | 2008 | Front Biosci2008，13，17： | 1 |
| 4 | NLRP6 inflamma some regulates colonic microbial ecology and risk for coli tis显示文摘 | Elinav E Strowig T Kau A L | 2011 | Ce112011，145，5： | 1 |
| 5 | Comparison of insulin monotherapy and combination therapy with insulin and metformin or insulin and troglitazone in type 2 diabetes显示文摘 | Strowig SM Aviles-Santa ML Raskin P | 2002 | Diabetes Care2002，25，10： | 1 |
| 6 | Comparison of different transformation methods for Aspergillus giganteus 显示文摘 | Meyer V Mueller D Strowig T | 2003 | Current Genetics2003，43，5： | 1 |
| 7 | NLRP6 inflammasomc regulates colonic microbial ecology and risk for colitis显示文摘 | Elinav E Strowig T Kau A L | 2011 | Cell2011，145，： | 1 |
| 8 | Comparison of different transformation methods for Aspergillus giganteus 显示文摘 | Meyer V Mueller D Strowig T | 2003 | Curr Genet2003，，43： | 1 |
| 9 | Regulation of the antimi-crobial response by NLR proteins显示文摘 | Elinav E Strowig T Henao-Mejia J | 2011 | Immunity2011，34，5： | 1 |
| 10 | Inflamma- somes in health and disease 显示文摘 | Strowig T Henao-Mejia J Elinav E | 2012 | Nature2012，481，： | 1 |
| 11 | Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes显示文摘 | Monique Gannagé Dorothee Dormann Randy Albrecht J?rn Dengjel Tania Torossi Patrick C. R?mer Monica Lee Till Strowig Frida Arrey Gina Conenello Marc Pypaert Jens Andersen Adolfo García-Sastre Christian Münz | 2009 | Cell Host & Microbe2009，，4： | 1 |
| 12 | Comparison of insulin monotherapy and combination therapy w ith insulin and mefformin or insulin and troglimzone in type 2 diabetes显示文摘 | Strowig SM Pe-santa ML Raskin P | 2002 | Diabetes Care2002，25，： | 1 |
| 13 | Matrix Protein 2 of Influenza A Virus Blocks Autophagosome Fusion with Lysosomes显示文摘 | Monique Gannagé Dorothee Dormann Randy Albrecht J?rn Dengjel Tania Torossi Patrick C. R?mer Monica Lee Till Strowig Frida Arrey Gina Conenello Marc Pypaert Jens Andersen Adolfo García-Sastre Christian Münz | 2009 | Cell Host & Microbe2009，，4： | 1 |
| 14 | NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis显示文摘 | Elinav E Strowig T Kau AL | 2011 | Cell2011，145，5： | 1 |
| 15 | Noncytotoxicfunctions of NK cells : direct pathogen restriction andassistance to adaptive immunity 显示文摘 | STROWIG T BRILOT F MtlNZ C | 2008 | J Immunol2008，180，12： | 1 |
| 16 | Comparison of different transformation methods for Aspergillus giganteus显示文摘 | Meyer V Mueller D Strowig T | 2003 | Curt Genet2003，43，5： | 1 |
| 17 | Inflammasomes in health and disease显示文摘 | Strowig T Henao-Mejia J Elinav E | 2012 | Nature2012，481，7381： | 1 |
| 18 | NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis显示文摘 | Elinav E Strowig T Kau AL | 2011 | Cell2011，145，： | 1 |
| 19 | NLRP6 inflammasome reg- ulates colonic microbial ecology and risk for colitis 显示文摘 | Elinav E Strowig T Kau Andrew L | 2011 | Cell2011，145，： | 1 |
| 20 | Comparison of different transformation methods for Aspergillus giganteus显示文摘 | Meyer V Mueller D Strowig T | | 0，，5： | 1 |
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