|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Mild closed head traumatic brain injury-induced changes in monoamine neurotransmitters in the trigeminal subnuclei of a rat model:mechanisms underlying orofacial allodynias and headache显示文摘Our recent findings have demonstrated that rodent models of closed head traumatic brain injury exhibit comprehensive evidence of progressive and enduring orofacial allodynias, a hypersensitive pain response induced by non-painful stimulation. These allodynias, tested using thermal hyperalgesia, correlated with changes in several known pain signaling receptors and molecules along the trigeminal pain pathway, especially in the trigeminal nucleus caudalis. This study focused to extend our previous work to investigate the changes in monoamine neurotransmitter immunoreactivity changes in spinal trigeminal nucleus oralis, pars interpolaris and nucleus tractus solitaries following mild to moderate closed head traumatic brain injury, which are related to tactile allodynia, touch-pressure sensitivity, and visceral pain. Our results exhibited significant alterations in the excitatory monoamine, serotonin, in spinal trigeminal nucleus oralis and pars interpolaris which usually modulate tactile and mechanical sensitivity in addition to the thermal sensitivity. Moreover, we also detected a robust alteration in the expression of serotonin, and inhibitory molecule norepinephrine in the nucleus tractus solitaries, which might indicate the possibility of an alteration in visceral pain, and existence of other morbidities related to solitary nucleus dysfunction in this rodent model of mild to moderate closed head traumatic brain injury. Collectively, widespread changes in monoamine neurotransmitter may be related to orofacial allodynhias and headache after traumatic brain injury. | Golam Mustafa Jiamei Hou Rachel Nelson Shigeharu Tsuda Mansura Jahan Naweed S.Mohammad Joseph V.Watts Floyd J.Thompson Prodip Bose | 2017 | Neural Regeneration Research2017，12，6： | 5 |
| 2 | A 10-kDa Structural Protein of Porcine Reproductive and Respiratory Syndrome Virus Encoded by ORF2b显示文摘 | Wai-Hong Wu Ying Fang Rachel Farwell Melissa Steffen-Bien Raymond R.R Rowland Jane Christopher-Hennings Eric A Nelson | 2001 | Virology2001，，1： | 1 |
| 3 | Effect of Interfacial Properties on Polymer–Nanocrystal Thermoelectric Transport显示文摘 | Nelson E. Coates Shannon K. Yee Bryan McCulloch Kevin C. See Arun Majumdar Rachel A. Segalman Jeffrey J. Urban | 2013 | Adv Mater2013，，11： | 1 |
| 4 | Concentrations of Steroid Hormones in Layers and Biopsies of Chelonian Egg Yolks显示文摘 | Rachel M. Bowden Michael A. Ewert Joseph L. Lipar Craig E. Nelson | 2001 | General and Comparative Endocrinology2001，，1： | 1 |
| 5 | The Power to Oblige: Power, Gender, Negotiation Behaviors, and Their Consequences显示文摘 | Nelson Noa Bronstein Ilan Shacham Rotem and Ben-Aft Rachel | 2015 | Negotiation and Conflict Management Research2015，8，1： | 1 |
| 6 | Ultrasonic-enhanced gentamicin transport through colony biofilms of Pseudomonas aeruginosa and Escherichia coli显示文摘 | John C. Carmen Jared L. Nelson Benjamin L. Beckstead Christopher M. Runyan Rachel A. Robison G. Bruce Schaalje William G. Pitt | 2004 | Journal of Infection and Chemotherapy2004，，4： | 1 |
| 7 | 母亲颗粒物空气污染暴露与足月出生体重:效应与异质性的多国评估显示文摘[背景]越来越多的证据显示,母亲空气污染暴露与对胎儿生长的不良影响之间存在关联;但是,现有的文献并不一致。[目的]研究9个国家14个中心的数据,量化母亲颗粒物空气污染暴露与足月出生体重和低出生体重(LBW)之间的关联,并探讨此关联中地点特征和暴露评估方法对中心之间异质性的影响。[方法]空气污染与妊娠结局国际合作(ICAPPO)的各中心采用共同的分析方案,对PM10和PM2.5(颗粒物≤10和2.5μm)与足月LBW和连续出生体重进行效应评估。采用meta分析将各个中心(~300万例出生)的效应评估结合起来,并采用meta回归分析在报告的效应评估中,中心特征和暴露评估方法对中心之间异质性的影响。[结果]随机效应meta分析显示,调整母亲的社会经济地位后,在整个妊娠期间,足月LBW与PM10[比值比(OR)=1.03;95%CI:1.01~1.05]和PM2.5[OR=1.10;95%CI:1.03~1.18]每增加10μg/m3呈正相关。在充分调整随机效应的meta分析中,作为一个连续性的结果,PM10暴露每增加10μg/m3与足月出生体重呈负相关(-8.9g;95%CI:-13.2^-4.6 g)。meta回归分析显示,具有较高平均PM2.5水平和PM2.5∶PM10比率的中心,以及采用时间暴露评估(与时空相比)的中心,所报告的关联更强。[结论]在研究人群中,母亲颗粒物污染暴露与足月LBW相关联。有3个地点特征和暴露评估方法学方面的不同导致各个中心报告的关联的差异。 | Payam Dadvand Jennifer Parker Michelle L. Bell Matteo Bonzini Michael Brauer Lyndsey A. Darrow Ulrike Gehring Svetlana V. Glinianaia Nelson Gouveia Eun-hee Ha Jong Han Leem Edith H. van den Hooven Bin Jalaludin Bill M. Jesdale Johanna Lepeule Rachel Morello-Frosch Geoffrey G. Morgan Angela Cecilia Pesatori Frank H. Pierik Tanja Pless-Mulloli David Q. Rich Sheela Sathyanarayana Juhee Seo Rémy Slama Matthew Strickland Lillian Tamburic Daniel Wartenberg Mark J. Nieuwenhuijsen Tracey J. Woodruff | 2013 | 环境与职业医学2013，30，6： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员