|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 中耳炎显示文摘中耳炎是儿童的高发病。中耳炎的病因病理是多因素的,包含免疫反应、咽鼓管功能障碍、细菌和病毒的感染、遗传以及环境因素等。早期的观察适用于大多数中耳炎儿童;对于被确诊为急性中耳炎的两岁以内的患儿,建议使用抗生素。手术方法的选择取决于合并症、儿童的生长发育状况以及对自发性渗出液的预期估计。推荐的手术方法有鼓室置管术、腺样体刮除术等。然而,到目前还没有理想的治疗方法,需要探索新的、基于现代中耳炎的病因病理理论的有创意性的治疗方法。 | Rovers MM Schilder AG Zielhuis GA Rosenfeld RM 张江平 杨妙丽 张全安 | 2005 | 国外医学(耳鼻咽喉科学分册)2005，29，3： | 427 |
| 2 | 分泌性中耳炎临床应用指南(2004版修订)显示文摘本指南基于循证医学的临床实践指南,为诊断、监测和管理儿童分泌性中耳炎提供建议。文章概括了临床决策建议,各项临床建议之间的关系以流程图(图1)表示。本指南强调合理诊断并对不同的管理策略提供选择,包括观察、医疗干预和转诊进行手术治疗。这些建议提供给初级保健医师和其他卫生保健人员来共同帮助管理儿童分泌性中耳炎。 | 魏兴梅 陈彪 崔丹默 郝欣平 陈树斌 王杰 李永新 rosenfeld rm shin jj schwartz sr | 2016 | 中国耳鼻咽喉头颈外科2016，23，8： | 64 |
| 3 | 秦岭地区气溶胶对地形云降水的抑制作用显示文摘以华山站为影响站,周围的西安、渭南和华阴作为对比站,通过影响站与对比站降水之比——地形强化因子(Ro)的变化趋势以及Ro与能见度关系的分析,定量研究了秦岭地区气溶胶对地形云降水的抑制作用。Ro的演变分析表明:有观测以来Ro逐年递减,减幅为14%~20%,即影响站与对比站相比降水量减少了14%~20%;Ro的减少趋势与能见度递减、气溶胶递增相吻合,说明气溶胶的增加抑制了地形云降水。Ro的递减主要是减少了中小雨(日雨量小于30 mm)的天数,这种影响对浅薄的生命期较短的地形云降水作用更明显,对于华山站,30 mm以下的降水都会受到入云气溶胶的抑制作用,而西安站为5 mm以下,入云气溶胶浓度越高,就有越厚的降水云受气溶胶影响而抑制降水;在以动力强迫抬升为主的春秋季,气溶胶抑制华山地形云降水20%左右,最大可达25%;在热对流条件下,气溶胶对地形云和对平原地区云的抑制作用基本相当。不同风速风向下Ro的变化趋势表明,Ro递减随风速增大而加快,迎风向(240°~30°)大风(≥5 m/s)时减少降水超过30%。由Ro与能见度关系的定量分析发现,当能见度在14 km时Ro为1.8左右,随着能见度的降低Ro逐渐减小,当能见度小于8 km时,R0约为1.2,减小了30%左右;华山对于华阴的Ro与能见度呈线性关系,相关系数达0.81。最后,根据研究结果归纳出气溶胶抑制秦岭地区地形云降水的初步物理模型。 | 戴进 余兴 Daniel ROSENFELD 徐小红 | 2008 | 大气科学2008，32，6： | 31 |
| 4 | MicroRNAs as a potential prognostic factor in gastric cancer显示文摘AIM:To compare the microRNA (miR) profiles in the primary tumor of patients with recurrent and non-recurrent gastric cancer.METHODS:The study group included 45 patients who underwent curative gastrectomies from 1995 to 2005 without adjuvant or neoadjuvant therapy and for whom adequate tumor content was available.Total RNA was extracted from formalin-fixed paraffin-embedded tumor samples,preserving the small RNA fraction.Initial profiling using miR microarrays was performed to identify potential biomarkers of recurrence after resection.The expression of the differential miRs was later verified by quantitative real-time polymerase chain reaction (qRT-PCR).Findings were compared between patients who had a recurrence within 36 mo of surgery (bad-prognosis group,n=14,31%) and those who did not (good-prognosis group,n=31,69%).RESULTS:Three miRs,miR-451,miR-199a-3p and miR-195 were found to be differentially expressed in tumors from patients with good prognosis vs patients with bad prognosis (P<0.0002,0.0027 and 0.0046 respectively).High expression of each miR was associated with poorer prognosis for both recurrence and survival.Using miR-451,the positive predictive value for non-recurrence was 100% (13/13).The expression of the differential miRs was verified by qRT-PCR,showing high correlation to the microarray data and similar separation into prognosis groups.CONCLUSION:This study identified three miRs,miR-451,miR-199a-3p and miR-195 to be predictive of recurrence of gastric cancer.Of these,miR-451 had the strongest prognostic impact. | Baruch Brenner Moshe B Hoshen Ofer Purim Miriam Ben David Karin Ashkenazi Gideon Marshak Yulia Kundel Ronen Brenner Sara Morgenstern Marisa Halpern Nitzan Rosenfeld Ayelet Chajut Yaron Niv Michal Kushnir | 2011 | World Journal of Gastroenterology2011，17，35： | 31 |
| 5 | 一次过冷层状云催化云迹微物理特征的卫星遥感分析显示文摘利用卫星反演技术,通过卫星观测到的一次人工增雨催化作业后形成的云迹线个例,分析了云迹线与其周围云的光谱特征、亮温、亮温差、云顶粒子有效半径等云微物理特征,比较了它们之间的差异,揭示了这次过冷层状云催化的微物理效应。云迹实际上是持续时间超过80 min、宽和深分别约为14 km和1.5 km的云谷。云迹周围的云顶粒子有效半径为10—15μm,而云沟内的粒子在15—24μm变化。周围云体由过冷滴组成,中间可能夹杂了一些低浓度的冰粒子,云沟内云的主要成分是冰。和周围未被催化的云相比,0.6μm通道的光谱反射率,在云沟处有明显的增加,而3.7μm通道反射率在云沟内是降低的,尽管其绝对变化幅度不大,但其相对变化幅度较大。随着播云时间的增加,云沟深度、宽度逐渐增加,云沟内和周围云体的温差逐渐增加,对通道4和5而言,在最早催化部位,最大分别达到4.2℃和3.9℃,4和5通道之间云沟内的亮温差也是随冰晶化时间的增加而增加,最大为1.4℃,而云沟周围云为0.2—0.4℃。云沟的形成、云沟内云顶温度的增加和4,5通道之间亮温差的增加,都足以说明被播云体变薄,其原因是由于云顶降水使得云内的水流失,云顶下降。云顶冰晶化、冰粒子增长成降水造成云顶下沉,是云沟形成的主要原因。对于本次播云作业,晶化作用在播云22 min后逐渐显现。在播云后38—63 min,有新的水云在云沟的中间部位生成,可能是由于冻结潜热释放引起的上升运动所致。而新生水云在形成较早的云迹中没有出现,这些较早形成的云迹在80多分钟的整个观测期间持续扩散。最终,在周围云从外向云沟内的扩散过程中,云沟开始消散。 | 戴进 余兴 Daniel Rosenfeld 徐小红 | 2006 | 气象学报2006，64，5： | 29 |
| 6 | 病理性近视脉络膜新生血管的治疗显示文摘病理性近视早期即可出现眼底病变且进行性加重,可导致视功能明显受损,其中脉络膜新生血管的发生是视力丧失的主要原因。文章对病理性近视的患病率、危害、自然转归、影响因素和治疗方法进行综述,着重探讨抗血管内皮生长因子药物治疗的进展。 | 许薇琦 Philip J Rosenfeld 孙晓东 | 2008 | 上海交通大学学报(医学版)2008，28，6： | 11 |
| 7 | 新型金属氧化物半导体场效应晶体管探测器在放疗剂量监控中的应用显示文摘目的探索和评估自行开发研制的新型金属氧化物半导体场效应晶体管(MOSFET)探测器在体实时剂量测量中的应用特性。方法分别使用医科达加速器8、15MV光子线,以及6、8、12、18 MeV电子束刻度MOSFET探测器。根据探测器灵敏度随能量变化情况评估MOSFET探测器能量依赖性。使用8MV光子线在0~50 Gy范围内观察MOSFET探测器读数随累积剂量变化的线性情况,确定MOSFET探测器剂量测量的线性区间。将MOSFET探测器固定在圆柱形PMMA体模中央,顺时针每15°检测探测器信号响应,判断MOSFET探测器方向性。对1例乳腺癌放疗患者应用MOSFET探测器进行了全程剂量监测。在使用NE-2571指形电离室对该患者放疗计划剂量计算进行物理验证后,分别于首次治疗、每周1次治疗及最后1次治疗中应用MOSFET探测器测量患者体表吸收剂量,并将测量结果与该处计划剂量进行比较,确定乳腺癌三维放疗的总体剂量偏差。结果对8、15 MV光子线和6~18MeV电子束测量结果显示,MOSFET探测器灵敏度随能量变化的幅度<2.5%。这表明MOSFET探测器对中高能射线具有较好的能量响应。在6 V门控电压状态下,MOSFET探测器在0~50 Gy的剂量范围内保持了较好的剂量线性,最大偏差<3.0%。在每次测量前和测量后分别刻度MOSFET探测器并取其平均值可使其剂量线性误差控制在1%以内。该MOSFET探测器信号响应在270~90°之间呈现出各向同性,读数偏差<1.5%。但在探测器背面(135~225°之间)的信号响应明显变小,背面与正面的读数偏差最大可达10.0%。应用于患者实时剂量监测的结果显示,实际测量剂量与计划剂量相比平均偏差2.8%,最大偏差<5.0%,符合AAPM 13号报告对体外放疗剂量总不确定度的质量控制标准。结论该MOSFEYT探测器体积小,操作简单,对中高能辐射具有较好的能量响应和剂量线性,为治疗计划剂量验证和人体吸收剂量测量提供了一种较好的剂量工具。 | 祁振宇 邓小武 黄劭敏 康德华 Anatoly Rosenfeld | 2006 | 中华放射肿瘤学杂志2006，15，4： | 8 |
| 8 | Face recognition显示文摘 | W. Zhao R. Chellappa P. J. Phillips A. Rosenfeld | 2003 | ACM Computing Surveys (CSUR)2003，，4： | 5 |
| 9 | A lincRNA switch for embryonic stem cell fate显示文摘 | Liuqing Yang Chunru Lin Michael G Rosenfeld | 2011 | Cell Research2011，21，12： | 4 |
| 10 | Aerosol–cloud–precipitation interactions. Part 1. The nature and sources of cloud-active aerosols显示文摘 | M.O. Andreae D. Rosenfeld | 2008 | Earth Science Reviews2008，，1： | 3 |
| 11 | 高剂量率后装近距离治疗^(192)铱放射源的校准显示文摘[目的]探讨使用井式电离室现场校准后装近距离治疗用192铱放射源的方法和规范。[方法]通过测量井式电离室对放射源位置的响应确定其最佳测量点;分别使用井式电离室和0.6cc指形电离室对临床后装治疗用高剂量率192铱放射源的活度进行重复校准测量,比较两者的测量重复性与精确度。[结果]井式电离室最佳校准测量点±5mm的测量误差小于5‰;对192铱放射源10次校准测量的平均偏差为0.71%,标准误0.37%,最大偏差小于1%。指形电离室借助测量定位支架在空气中对同一192铱放射源校准测量的平均偏差为1.48%,标准误1.99%;最大偏差小于3%。[结论]使用井式电离室可以极大地减少铱源校准测量的环节,测量重复性和精度均优于指形电离室。 | 祁振宇 邓小武 黄劭敏 ANATOLY ROSENFELD | 2008 | 中国肿瘤2008，17，8： | 3 |
| 12 | An Optical Coherence Tomography-Guided, Variable Dosing Regimen with Intravitreal Ranibizumab (Lucentis) for Neovascular Age-related Macular Degeneration显示文摘 | Anne E. Fung Geeta A. Lalwani Philip J. Rosenfeld Sander R. Dubovy Stephan Michels William J. Feuer Carmen A. Puliafito Janet L. Davis Harry W. Flynn Maria Esquiabro | 2007 | American Journal of Ophthalmology2007，，4： | 3 |
| 13 | Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis显示文摘 | Josep Dalmau Eric Lancaster Eugenia Martinez-Hernandez Myrna R Rosenfeld Rita Balice-Gordon | 2011 | Lancet Neurology2011，，1： | 3 |
| 14 | Clinical practice guideline: Benign paroxysmal positional vertigo显示文摘 | Neil Bhattacharyya Reginald F. Baugh Laura Orvidas David Barrs Leo J. Bronston Stephen Cass Ara A. Chalian Alan L. Desmond Jerry M. Earll Terry D. Fife Drew C. Fuller James O. Judge Nancy R. Mann Richard M. Rosenfeld Linda T. Schuring Robert W.P. Steiner | 2008 | Otolaryngology - Head and Neck Surgery2008，，5： | 3 |
| 15 | Performance analysis of a simple vehicle detection algorithm显示文摘 | Moon H Chellappa R Rosenfeld A | 2002 | Image and Vision Computing2002，20，： | 2 |
| 16 | ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs显示文摘 | Liuqing Yang Chunru Lin Wen Liu Jie Zhang Kenneth A. Ohgi Jonathan D. Grinstein Pieter C. Dorrestein Michael G. Rosenfeld | 2011 | Cell2011，，4： | 2 |
| 17 | Relationship between visual evoked potentials and intracranial pressure显示文摘 | York DH Pulliam MW Rosenfeld JG | 1981 | J Neurosurg1981，55，： | 2 |
| 18 | Systemic Bevacizumab (Avastin) Therapy for Neovascular Age-Related Macular Degeneration显示文摘 | Stephan Michels Philip J. Rosenfeld Carmen A. Puliafito Erin N. Marcus Anna S. Venkatraman | 2005 | Ophthalmology2005，，6： | 2 |
| 19 | Does training and experience influence the accuracy of computed tomography colonography interpretation?显示文摘AIM: To evaluate the effect of experience on the accuracy rate of computed tomography colonography(CTC) interpretation and patient preferences/satisfaction for CTC and colonoscopy. METHODS: A prospective, non-randomized, observational study performed in a single, tertiary care center involving 90 adults who underwent CTC followed by colonoscopy on the same day. CTC was interpreted by an abdominal imaging radiologist and then a colonoscopy was performed utilizing segmental un-blinding and re-examination as required. A radiology resident and two gastroenterology(GI) fellows blinded to the results also interpreted the CTC datasets independently. Accuracy rates and trend changes were determined for each reader to assess for a learning curve. RESULTS: Among 90 patients(57% male) aged 55 ± 8.9 years, 39 polyps ≥ 6 mm were detected in 20 patients and 13 polyps > 9 mm in 10 patients. Accuracy rates were 88.9%(≥ 6 mm) and 93.3%(> 9 mm) for the GI Radiologist, 89.8%(≥ 6 mm) and 98.9%(> 9 mm) for the Radiology Resident and 86.7% and 95.6%(≥ 6 mm) and 87.8% and 94.4%(> 9 mm) for each of the GI fellows respectively. The reader's accuracy rate did not change significantly with the percentage change rate ranging between-1.7 to 0.9(P = 0.12 to 0.56). Patients considered colonoscopy more satisfactory than CTC(30% vs 4%, P < 0.0001), they felt less anxiety during colonoscopy(36% vs 7%, P < 0.0001), they experienced less pain or discomfort during colonoscopy compared to CTC(69% vs 4%, P < 0.0001) and colonoscopy was preferred by 77% of the participants as a repeat screening test for the future. CONCLUSION: No statistically significant learning curve was identified in CTC interpretation suggesting that further study is required to identify the necessary training to adequately interpret CTC scans. | Greg Rosenfeld Yi Tzu Nancy Fu Brendan Quiney Hong Qian Darin Krygier Jacquie Brown Patrick Vos Pari Tiwari Jennifer Telford Brian Bressler Robert Enns | 2014 | World Journal of Gastroenterology2014，20，6： | 2 |
| 20 | FOCUS: Future of fecal calprotectin utility study in inflammatory bowel disease显示文摘AIM To evaluate the perspective of gastroenterologists regarding the impact of fecal calprotectin(FC) on the management of patients with inflammatory bowel disease(IBD).METHODS Patients with known IBD or symptoms suggestive of IBD for whom the physician identified that FC would be clinically useful were recruited. Physicians completed an online 'pre survey' outlining their rationale for the test. After receipt of the test results, the physicians completed an online 'post survey' to portray their perceived impact of the test result on patient management. Clinical outcomes for a subset of patients with follow-up data available beyond the completion of the 'post survey' were collected and analyzed.RESULTS Of 373 test kits distributed, 290 were returned, resulting in 279 fully completed surveys. One hundred and ninety patients were known to have IBD; 147(77%) with Crohn's Disease, 43(21%) Ulcerative Colitis and 5(2%) IBD unclassified. Indications for FC testing included: 90(32.2%) to differentiate a new diagnosis of IBD from Irritable Bowel Syndrome(IBS), 85(30.5%) to distinguish symptoms of IBS from IBD in those known to have IBD and 104(37.2%) as an objective measure of inflammation. FC levels resulted in a change in management 51.3%(143/279) of the time which included a significant reduction in the number of colonoscopies(118) performed(P < 0.001). Overall, 97.5%(272/279) of the time, the physicians found the test sufficiently useful that they would order it again in similar situations. Follow-up data was available for 172 patients with further support for the clinical utility of FC provided.CONCLUSION The FC test effected a change in management 51.3% of the time and receipt of the result was associated with a reduction in the number of colonoscopies performed. | Greg Rosenfeld Astrid-Jane Greenup Andrew Round Oliver Takach Lawrence Halparin Abid Saadeddin Jin Kee Ho Terry Lee Robert Enns Brian Bressler | 2016 | World Journal of Gastroenterology2016，22，36： | 2 |
您所在的机构暂未开通此部分的功能，请联系管理员