|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Crop Breeding Chips and Genotyping Platforms: Progress, Challenges, and Perspectives显示文摘在为基因在领域庄稼和树印射和发现的分子的标记试金的开发和应用程序有一个很快升起的趋势。因此 ? 远,超过 50 个 SNP 数组和 genotyping-by-sequencing (GBS ) 的 15 种不同类型平台在超过 25 庄稼种类和长期的树被开发了。然而,少得多努力在为引起程序使用开发 ultra-high-throughput 和划算的 genotyping 平台上被作了。在这评论,我们在存在 SNP 数组和 GBS 技术和策略讨论科学瓶颈开发指向的平台为收割分子的繁殖。我们建议实际繁殖平台应该采用的那未来自动化了 genotyping 技术,任何一个数组或定序基于,目标 ? 功能的多型性 underpinning 经济特点,并且为量的特点提供理想的预言精确性,用在在庄稼的宽基因背景下面的通用应用程序。如此的平台的发展在庄稼植物由于大遗传型显型差距由于费用低效率,和知识水平在工艺的水平面对严肃的挑战。如此的 genotyping 平台将在考虑在主要庄稼在下一十年里被完成,这被期望?(a)快速的开发?在重要特点的基因发现,(b)通过新分析模型和人口图案加深了量的特点的理解,导致基因和为重要繁殖特点负责的小径的鉴定的多层的 -omics 数据的(c)集成,和在大规模 genotyping 的费用有效性的(d)改进。庄稼繁殖芯片和 genotyping 平台将提供崭新的机会与减轻气候变化的效果的需要的收益潜力,质量,和提高的改编加速栽培变种的开发。 | Awais Rasheed Yuanfeng Hao Xianchun Xia Awais Khan Yunbi Xu Rajeev K. Varshney Zh-onghu He | 2017 | Molecular Plant2017，10，8： | 42 |
| 2 | 战略决策过程:批判性回顾与未来研究展望显示文摘本文在对以往文献进行回顾的基础上,构建了一个战略决策过程的整合框架。该框架将决策过程特征的前置因素(环境因素、组织因素和决策专有因素)及其过程结果和经济结果整合在一起。依据该框架,本文对重要的实证研究文献进行了综述,指出了主要的研究模式以及研究成果中的矛盾之处。在综述的基础上,文章还探讨了本研究对于理论构建、研究方法和管理实践的启示,并指出了未来研究的一些方向。 | Nandini Rajagopalan Abdul M. A. Rasheed Deepak K. Datta 苗莉(译) | 2012 | 管理世界2012，28，1： | 15 |
| 3 | Therapeutic upper gastrointestinal tract endoscopy in Paediatric Gastroenterology显示文摘Since the first report of use of endoscopy in children in the 1970 s, there has seen an exponential growthin published experience and innovation in the field. In this review article we focus on modern age therapeutic endoscopy practice, explaining use of traditional as well as new and innovative techniques, for diagnosis and treatment of diseases in the paediatric upper gastrointestinal tract. | Imdadur Rahman Praful Patel Philip Boger Shahnawaz Rasheed Mike Thomson Nadeem Ahmad Afzal | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，3： | 14 |
| 4 | Liver transplantation in alcoholic liver disease current status and controversies显示文摘Alcoholic cirrhosis remains the second most common indication for liver transplantation.A comprehensive medical and psychosocial evaluation is needed when making a decision to place such patients on the transplant list.Most transplant centers worldwide need a minimum of 6 mo of alcohol abstinence for listing these patients.Patients with alcohol dependence are at high risk for relapse to alcohol use after transplantation(recidivism).These patients need to be identified and require alcohol rehabilitation treatment before transplantation.Recidivism to the level of harmful drinking is reported in about 15%-20%cases.Although,recurrent cirrhosis and graft loss from recidivism is rare,occurring in less than 5%of all alcoholic cirrhosis-related transplants,harmful drinking in the post-transplant pe-riod does impact the long-term outcome.The development of metabolic syndrome with cardiovascular events and de novo malignancy are important contributors to non liver-related mortality amongst transplants for alcoholic liver disease.Surveillance protocols for earlier detection of de novo malignancy are needed to improve the long-term outcome.The need for a minimum of 6 mo of abstinence before listing makes transplant a nonviable option for patients with severe alcoholic hepatitis who do not respond to corticosteroids.Emerging data from retrospective and prospective studies has challenged the 6 mo rule,and beneficial effects of liver transplantation have been reported in select patients with a first episode of severe alcoholic hepatitis who are unresponsive to steroids. | Ashwani K Singal Khushdeep S Chaha Khalid Rasheed Bhupinderjit S Anand | 2013 | World Journal of Gastroenterology2013，19，36： | 12 |
| 5 | 植物乳杆菌D1501发酵黄浆水的抑菌活性及其中细菌素的分离与鉴定显示文摘将植物乳杆菌D1501(Lactobacillus plantarum D1501)接种于黄浆水中,37℃静置培养24 h后制成酸浆。抑菌活性测定表明,该方法制备的酸浆对供试的革兰氏阳性菌、革兰氏阴性菌具有明显的抗菌活性,对假丝酵母有弱的抑菌活性,但对酿酒酵母和2株霉菌没有抑制作用。经中和及酶解实验推测酸浆中的抑菌物质为细菌素。将经过30、10、3 kDa超滤分离得到的无细胞超滤液旋蒸浓缩定容后,采用RESOURCE-Q阴离子交换柱和300SB-C18反相层析柱依次纯化,得到色谱纯度细菌素物质,命名为Lp100。该细菌素经液相色谱-串联质谱法分析,确定分子质量约为1434.90 Da,氨基酸序列为MCCKVLLLLSRR。最终细菌素比活力为7247.00 IU/mg,纯化倍数为79.94倍,回收率为1%。 | 陆洲 戴意强 Hafiz Abdul RASHEED 吴寒 夏秀东 董明盛 | 2020 | 食品科学2020，41，24： | 8 |
| 6 | Systematic review of emergent laparoscopic colorectal surgery for benign and malignant disease显示文摘Laparoscopic surgery has become well established in the management of both and malignant colorectal disease.The last decade has seen increasing numbers of surgeons trained to a high standard in minimallyinvasive surgery.However there has not been the same enthusiasm for the use of laparoscopy in emergency colorectal surgery.There is a perception that emergent surgery is technically more difficult and may lead to worse outcomes.The present review aims to provide a comprehensive and critical appraisal of the available literature on the use of laparoscopic colorectal surgery(LCS)in the emergency setting.The literature is broadly divided by the underlying pathology;that is,inflammatory bowel disease,diverticulitis and malignant obstruction.There were no randomized trials and the majority of the studies were case-matched series or comparative studies.The overall trend was that LCS is associated with shorter hospital stay,par or fewer complications but an increased operating time.Emergency LCS can be safely undertaken for both benign and malignant disease providing there is appropriate patient selection,the surgeon is adequately experienced and there are sufficient resources to allow for a potentially more complex operation. | Manish Chand Muhammed RS Siddiqui Ashish Gupta Shahnawaz Rasheed Paris Tekkis Amjad Parvaiz Alex H Mirnezami Tahseen Qureshi | 2014 | World Journal of Gastroenterology2014，20，45： | 7 |
| 7 | INHIBITORY EFFECT OF TRIMETAZIDINE ON CARDIAC MYOCYTE APOPTOSIS IN RABBIT MODEL OF ISCHEMIA-REPERFUSION显示文摘 | Rasheed AL-ghazali | 2004 | Chinese Medical Sciences Journal2004，19，4： | 6 |
| 8 | A Covert Communication Method Using Special Bitcoin Addresses Generated by Vanitygen显示文摘As an extension of the traditional encryption technology,information hiding has been increasingly used in the fields of communication and network media,and the covert communication technology has gradually developed.The blockchain technology that has emerged in recent years has the characteristics of decentralization and tamper resistance,which can effectively alleviate the disadvantages and problems of traditional covert communication.However,its combination with covert communication thus far has been mostly at the theoretical level.The BLOCCE method,as an early result of the combination of blockchain and covert communication technology,has the problems of low information embedding efficiency,the use of too many Bitcoin addresses,low communication efficiency,and high costs.The present research improved on this method,designed the V-BLOCCE which uses base58 to encrypt the plaintext and reuses the addresses generated by Vanitygen multiple times to embed information.This greatly improves the efficiency of information embedding and decreases the number of Bitcoin addresses used.Under the premise of ensuring the order,the Bitcoin transaction OP_RETURN field is used to store the information required to restore the plaintext and the transactions are issued at the same time to improve the information transmission efficiency.Thus,a more efficient and feasible method for the application of covert communication on the blockchain is proposed.In addition,this paper also provides a more feasible scheme and theoretical support for covert communication in blockchain. | Lejun Zhang Zhijie Zhang Weizheng Wang Rasheed Waqas Chunhui Zhao Seokhoon Kim Huiling Chen | 2020 | Computers, Materials & Continua2020，，10： | 6 |
| 9 | Phenotypic methods of greater accuracy to detect the mecA gene product for the recognition of MRSA in resource constraint settings显示文摘Objective:To evaluate the detection of methicillin resistant Staphylococcus aureus(MRSA) and analyze the performance of Mastalex MRSA(Mast,UK).Methods:Two hundred and ten Staphylococcus aureus(S.aureus) strains were isolated from different clinical samples and were tested for methicillin resistance by Oxacillin(1μg) and Cefoxitin(30μg) disc diffusion, oxacillin agar screen,and minimum inhibitory concentration of oxacillin and cefoxitin.S.aureus isolates were grown on the blood agar and mannitol salt agar with(2 mg/L) and without oxacillin for the analysis of Mastalex MRSA.Results:Out of 210 S.aureus strains tested,103 strains were detected as methicillin resistant by Cefoxitin disk diffusion,Cefoxitin minimal inhibitory concentration(MlC) and Mastalex MRSA test.Whereas oxacillin disc diffusion and oxacillin agar screen detected 91 and 97 MRSA respectively.The Cefoxitin MIC test performance was equivalent to Cefoxitin disc diffusion.103(100%) strains grown on blood agar without and with oxacillin,and 76(74%) and 93(91%) strains grown on mannitol salt agar without and with oxacillin shown positive agglutination with Mastalex MRSA test respectively.Conclusions:The cefoxitin disk diffusion/ Mastalex MRSA is very suitable for detection of MRSA and the tests can be an alternative to PCR for detection of MRSA in resource constraint settings.Mastalex test would be particularly useful when confirmation of resistance is urgently required. | Rasheed MU Ahmed Z | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，9： | 6 |
| 10 | Development of image-based wheat spike counter through a Faster R-CNN algorithm and application for genetic studies显示文摘Spike number(SN) per unit area is one of the major determinants of grain yield in wheat. Development of high-throughput techniques to count SN from large populations enables rapid and cost-effective selection and facilitates genetic studies. In the present study, we used a deep-learning algorithm, i.e., Faster Region-based Convolutional Neural Networks(Faster R-CNN) on Red-Green-Blue(RGB) images to explore the possibility of image-based detection of SN and its application to identify the loci underlying SN. A doubled haploid population of 101 lines derived from the Yangmai 16/Zhongmai 895 cross was grown at two sites for SN phenotyping and genotyped using the high-density wheat 660 K SNP array.Analysis of manual spike number(MSN) in the field, image-based spike number(ISN), and verification of spike number(VSN) by Faster R-CNN revealed significant variation(P < 0.001) among genotypes, with high heritability ranged from 0.71 to 0.96. The coefficients of determination(R^(2)) between ISN and VSN was 0.83, which was higher than that between ISN and MSN(R^(2)= 0.51), and between VSN and MSN(R^(2)= 0.50). Results showed that VSN data can effectively predict wheat spikes with an average accuracy of 86.7% when validated using MSN data. Three QTL Qsnyz.caas-4 DS, Qsnyz.caas-7 DS, and QSnyz.caas-7 DL were identified based on MSN, ISN and VSN data, while QSnyz.caas-7 DS was detected in all the three data sets. These results indicate that using Faster R-CNN model for image-based identification of SN per unit area is a precise and rapid phenotyping method, which can be used for genetic studies of SN in wheat. | Lei Li Muhammad Adeel Hassan Shurong Yang Furong Jing Mengjiao Yang Awais Rasheed Jiankang Wang Xianchun Xia Zhonghu He Yonggui Xiao | 2022 | The Crop Journal2022，10，5： | 5 |
| 11 | Energy optimization in the wake of China Pakistan Economic Corridor(CPEC)显示文摘The energy crisis has become a significant bottleneck in the country’s economic progress.But to end this age old problem,we have to capitalize on the chance,China Pakistan Economic Corridor(CPEC)investment provides,to its full potential.This study aims to help Pakistani government in selecting the best set of CPEC energy priority projects to be completed in the first wave of development.The second part of the research guides the small/medium scale industry and business owners to select the best available alternative for tackling the energy shortfall while CPEC projects are in the process of materialization.Forecasting electricity shortfall decrease and its impact on various economic/industrial sectors(like services,industrial,textile and agriculture)is also performed to gauge the effect of CPEC on the economy using linear regression.For decision analysis,the MCDM techniques employed are(AHP)along with(TOPSIS).This research generated a new list of recommended CPEC energy priority projects which are more evenly distributed across the country,catering more,to interest of the country as a whole.We also concluded solar panels to be the best alternative for small scale businesses,as short term solution while CPEC projects are under construction. | Yousaf Ali Zaeem Rasheed Noor Muhammad Salman Yousaf | 2018 | Journal of Control and Decision2018，5，2： | 5 |
| 12 | Design,synthesis,and biological evaluation of novel benzimidazole derivatives and their interaction with calf thymus DNA and synergistic effects with clinical drugs显示文摘A series of new benzimidazole derivatives was synthesized and characterized by IR,1H NMR,13C NMR,MS,and HRMS spectra.All the new compounds were screened for their antimicrobial activities in vitro by a twofold serial dilution technique.The bioactive evaluation showed that 3,5-bis(trifluoromethyl)phenyl benzimidazoles were comparably or even more strongly antibacterial and antifungal than the reference drugs Chloromycin,Norfloxacin,and Fluconazole.The combination of2,4-difluorobenzyl benzimidazole derivative 5l and its hydrochloride 7 respectively with the antibacterials Chloromycin,Norfloxacin,and the antifungal Fluconazole was more sensitive to methicillin-resistant MRSA and Fluconazole-insensitive A.flavus.In addition,the interaction of compound 5l with calf thymus DNA demonstrated that this compound could effectively intercalate into DNA to form a compound 5l-DNA complex that might block DNA replication and thereby exert good antimicrobial activity. | ZHANG HuiZhen LIN JianMei RASHEED Syed ZHOU ChengHe | 2014 | Science China Chemistry2014，57，6： | 5 |
| 13 | Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer显示文摘 | Shinichi Yabuuchi Shweta G. Pai Nathaniel R. Campbell Roeland F. de Wilde Elizabeth De Oliveira Preethi Korangath Mirte M. Streppel Zeshaan A. Rasheed Manuel Hidalgo Anirban Maitra N.V. Rajeshkumar | 2013 | Cancer Letters2013，，1： | 5 |
| 14 | 槟榔子中抗血小板聚集及抑制乙酰胆碱酯酶活性的有效成分(英文)显示文摘目的:研究槟榔子(Areca catechu)粗提取物中所含的抗血小板聚集及抑制乙酰胆碱酯酶活性的有效成分及其作用机制。方法:使用70%甲醇水溶液对槟榔子进行粗提取。使用生物发光血小板凝集仪在富血小板血浆中测定槟榔子粗提取物的抗血小板聚集作用,使用分光光度计在试管内测定槟榔子粗提取物对乙酰胆碱酯酶活性的抑制作用。检测槟榔子中的多种化合物以测定槟榔子中抗血小板聚集及抑制乙酰胆碱酯酶活性的有效成分。结果:槟榔子粗提取物能够抑制花生四烯酸、二磷酸腺苷、血小板活化因子、肾上腺素及钙离子载体引起的血小板聚集,尤其对二磷酸腺苷及钙离子载体引起的血小板聚集的抑制最为明显;槟榔子粗提取物能够显著抑制乙酰胆碱酯酶的活性。在所检测的槟榔子所含化合物中,只有儿茶素对肾上腺素引起的血小板聚集有显著的抑制作用,而这种抑制作用显著弱于槟榔子粗提取物,提示槟榔子中的其他成分参与了这种抑制作用;鞣酸、没食子酸、薯蓣皂苷元和异去甲槟榔次碱能够抑制乙酰胆碱酯酶的活性,其中鞣酸的抑制作用强于槟榔子粗提取物。结论:槟榔子中含有抗血小板聚集及抑制乙酰胆碱酯酶活性的有效成分,而发挥这些功效的确切成分有待进一步的研究证实。 | Muhammad Nabeel Ghayur Syed Faraz Kazim Huma Rasheed Asaad Khalid Maliha Iqbal Jumani Muhammad Iqbal Choudhary Anwarul Hassan Gilani | 2011 | 中西医结合学报2011，9，6： | 4 |
| 15 | Obese patients have similar short-term outcomes to nonobese in laparoscopic colorectal surgery显示文摘AIM: To determine whether obese patients undergoing laparoscopic surgery within an enhanced recovery program had worse short-term outcomes.METHODS: A prospective study of consecutive patients undergoing laparoscopic colorectal resection was carried out between 2008 and 2011 in a single institution. Patients were divided in groups based on body mass index(BMI). Short-term outcomes including operative data, length of stay, complications and readmission rates were recorded and compared between the groups. Continuous data were analysed using t-test or oneway Analysis of Variance. χ2 test was used to compare categorical data.RESULTS: Two hundred and fifty four patients were included over the study period. The majority of individuals(41.7%) recruited were of a healthy weight(BMI < 25), whilst 50 patients were classified as obese(19.6%). Patients were matched in terms of the presence of comorbidities and previous abdominal surgery. Obese patients were found to have a statistically significant difference in The American Society of Anesthesiologists grade. Length of surgery and intra-operative blood loss were no different according to BMI.CONCLUSION: Obesity(BMI > 25) does not lead to worse short-term outcomes in laparoscopic colorectal surgery and therefore such patients should not be precluded from laparoscopic surgery. | Manish Chand Henry D De'Ath Muhammed Siddiqui Chetanya Mehta Shahnawaz Rasheed James Bromilow Tahseen Qureshi | 2015 | World Journal of Gastrointestinal Surgery2015，7，10： | 4 |
| 16 | )plication of geo-microbial prospecting method for finding oil and gas reservoirs显示文摘 | M. A. Rasheed Syed Zaheer Hasan P. L. Srinivasa Rao Annapurna Boruah V.Sudarshan B. Kumar T. Harinarayana | 2015 | Frontiers of Earth Science2015，9，1： | 3 |
| 17 | Design,synthesis and biological evaluation of amino organophosphorus imidazoles as a new type of potential antimicrobial agents显示文摘A series of amino organophosphorus imidazoles were designed and synthesized as a novel structural type of antimicrobial agents.Bioactive evaluation in vitro showed that compound 3f exhibited equipotent or superior anti-methicillin-resistant Staphylococcus aureus(anti-MRSA) and anti-S. cerevisiae efficiencies(minimal inhibitory concentration(MIC)=2 μg/mL) to clinical drugs,and the combinations with antibacterial or antifungal drugs enhanced the antimicrobial efficiency. Highly active molecule 3f showed low propensity for bacteria to develop resistance, and the preliminary action mechanism studies demonstrated that 3f was membrane-active, but had no significant intercalation towards MRSA DNA. The computational study on 3f reasonably explained its high antimicrobial activity. Experimental data revealed that ground-state 3f-HSA complexes were formed mainly through hydrophobic interactions and hydrogen bonds with a spontaneous process, and the non-radioactive energy transfer from HSA to 3f occurred beyond F鰎ster resonance energy transfer theory. The participation of metal ions in 3f-HSA supramolucular system could increase the concentration of free compound 3f, and shorten its storage time and half-life in the blood to improve the maximum antimicrobial efficacy. | Wei-Wei Gao Syed Rasheed VijaiKumarReddy Tangadanchu Yi Sun Xin-Mei Peng Yu Cheng Feng-Xiu Zhang Jian-Mei Lin Cheng-He Zhou | 2017 | Science China Chemistry2017，60，6： | 3 |
| 18 | DNNGP, a deep neural network-based method for genomic prediction using multi-omics data in plants显示文摘Genomic prediction is an effective way to accelerate the rate of agronomic trait improvement in plants.Traditional methods typically use linear regression models with clear assumptions;such methods are unable to capture the complex relationships between genotypes and phenotypes.Non-linear models(e.g.,deep neural networks)have been proposed as a superior alternative to linear models because they can capture complex non-additive effects.Here we introduce a deep learning(DL)method,deep neural network genomic prediction(DNNGP),for integration of multi-omics data in plants.We trained DNNGP on four datasets and compared its performance with methods built with five classic models:genomic best linear unbiased prediction(GBLUP);two methods based on a machine learning(ML)framework,light gradient boosting machine(LightGBM)and support vector regression(SVR);and two methods based on a DL framework,deep learning genomic selection(DeepGS)and deep learning genome-wide association study(DLGWAS).DNNGP is novel in five ways.First,it can be applied to a variety of omics data to predict phenotypes.Second,the multilayered hierarchical structure of DNNGP dynamically learns features from raw data,avoiding overfitting and improving the convergence rate using a batch normalization layer and early stopping and rectified linear activation(rectified linear unit)functions.Third,when small datasets were used,DNNGP produced results that are competitive with results from the other five methods,showing greater prediction accuracy than the other methods when large-scale breeding data were used.Fourth,the computation time required by DNNGP was comparable with that of commonly used methods,up to 10 times faster than DeepGS.Fifth,hyperparameters can easily be batch tuned on a local machine.Compared with GBLUP,LightGBM,SVR,DeepGS and DLGWAS,DNNGP is superior to these existing widely used genomic selection(GS)methods.Moreover,DNNGP can generate robust assessments from diverse datasets,including omics data,and quickly incorporate complex and large datasets into usable models,making it a promising and practical approach for straightforward integration into existing GS platforms. | Kelin Wang Muhammad Ali Abid Awais Rasheed Jose Crossa Sarah Hearne Huihui Li | 2023 | Molecular Plant2023，16，1： | 3 |
| 19 | A review of dengue as an emerging disease in Pakistan显示文摘 | S.B. Rasheed R.K. Butlin M. Boots | 2012 | Public Health2012，，： | 3 |
| 20 | Instrumental detection of cystic duct stones during laparoscopic cholecystectomy显示文摘Residual cystic duct stones (CDSs) after cholecystectomy have been recognized as a cause of post cholecystectomy pain. This study was undertaken to determine the incidence of CDSs during laparoscopic cholecystectomy(LC). A cohort of 330 consecutive patients (80 males and 250females) undergoing LC between November 2006 and May2010 was studied. Their age ranged between 16 and 88 years(median 50, IQR: 36.62). The data were prospectively collected of preoperative liver function tests, imaging, the presence of intraoperative CDSs, and common bile duct stones at on-table cholangiogram. CDSs were detected intraoperatively in 64 of the 330 patients (19%). Ultrasound failed to detect CDSs in any of these cases. Deranged liver function tests were noted in 73% of the patients with CDSs and in 57% without CDSs Common bile duct stones were detected in 9% (29) of the 330patients. CDSs occur commonly at routine cholecystectomy, and preoperative investigations are not helpful in their diagnosis As CDSs may lead to postoperative morbidity, they should be actively sought out during surgery if present. | Amir Kambal Tomos Richards Harsha Jayamanne Zeyed Sallami Ashraf Rasheed Taha Lazim | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，2： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员