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| 1 | The Structural Features of Thousands of T-DNA Insertion Sites Are Consistent with a Double- Strand Break Repair-Based Insertion Mechanism显示文摘由 Agrobacterium tumefaciens 的转变,在现代植物研究的一个重要工具,在 agrobacteria 包含在 plasmid 上开始在场的 T-DNA 的集成进植物房间的染色体。到植物房间和到原子核的进房间并且进一步的 T-DNA 的运输的 agrobacteria 的附件的过程很好被描述了。然而,进 host’s DNA 的集成的准确机制仍然是不清楚的,尽管几个模型被建议了。在从 Arabidopsis thaliana 异种的 GABI-Kat 收集的 T-DNA 插入等位基因的证实期间,我们从在插入的 T-DNA 和邻近的染色体区域之间的连接产生了大约 34000 个序列。这里,我们为 T-DNA 集成关于存在模型描述这数据集的评估。结果建议进植物染色体的集成被内长的植物 DNA 修理机械主要调停。观察集成事件证明双海滨的修理地点的高度类似于那些的特征与尊重决裂到 microhomology 和删除尺寸。另外,我们描述意外集成事件,例如在为从在反向的遗传实验的 T-DNA 插入异种的结果的正确解释是相关的集成地点的大删除和倒置。 | Nils Kleinboelting Gunnar Huep Ingo Appelhagen Prisca Viehoever Yong Li Bernd Weisshaar | 2015 | Molecular Plant2015，8，11： | 4 |
| 2 | In search of the phylogenetic affinity of the temperate woody bamboos from Madagascar, with description of a new species (Bambusoideae, Poaceae)显示文摘六根适度的木质的竹子(Arundinarieae, Bambusoideae ) 在 1920 年代期间在类 Arundinaria 从马达加斯加被描述到 1960 年代。然而,最近的种系发生的研究暗示 Arundinaria 被限制为北美洲,并且马尔加什人适度的木质的竹子的分类联营仍然保持模糊。寻找这些的种系发生的亲密关系,竹子,腊叶集观察,现场考古工作,和分子的种系发生的分析被执行了。他们和一个中的四个潜在的新种类在部落 Arundinarieae 的上下文为分子的种系发生的分析被取样。最大的可能性的和贝叶斯的分析显示那那些种仔细在大陆人非洲,然而并非 Arundinaria 与 Oldeania alpina 有关被散布, Bergbambos, Fargesia (包括的 Sinarundinaria ) , Thamnocalamus,或 Yushania,他们有时在被放。在分子的发展史,形态学,和 phytogeography 的根据上,马尔加什人适度的木质的竹子应该被当作类 Oldeania 的成员。Arundinaria humbertii 和 A。ambositrensis 是同种的。新种, Oldeania itremoensis,被描述并且说明。在没在分子的发展史取样的马达加斯加的另外的二适度的木质的竹子种也根据形态学被转移到 Oldeania。 | Yu-Xiao Zhang Peng-Fei Ma Thomas Havermans Maria S. Vorontsova Ting Zhang Olinirina Prisca Nanjarisoa De-Zhu Li | 2017 | Journal of Systematics and Evolution2017，55，5： | 2 |
| 3 | UV-B light and its application potential to reduce disease and pest incidence in crops显示文摘Ultraviolet-B radiation(280–315 nm),perceived by the plant photoreceptor UVR8,is a key environmental signal that influences plant growth and development and can reduce disease and pest incidence.The positive effect of UV-B on disease resistance and incidence in various plant species supports the implementation of supplemental UV-B radiation in sustainable crop production.However,despite many studies focusing on UV-B light,there is no consensus on the best mode of application.This review aims to analyze,evaluate,and organize the different application strategies of UV-B radiation in crop production with a focus on disease resistance.We summarize the physiological effects of UV-B light on plants and discuss how plants perceive and transduce UV-B light by the UVR8 photoreceptor as well as how this perception alters plant specialized metabolite production.Next,we bring together conclusions of various studies with respect to different UV-B application methods to improve plant resistance.In general,supplemental UV-B light has a positive effect on disease resistance in many plant–pathogen combinations,mainly through the induction of the production of specialized metabolites.However,many variables(UV-B light source,plant species,dose and intensity,timing during the day,duration,background light,etc.)make it difficult to compare and draw general conclusions.We compiled the information of recent studies on UV-B light applications,including e.g.,details on the UV-B light source,experimental set-up,calculated UV-B light dose,intensity,and duration.This review provides practical insights and facilitates future research on UV-B radiation as a promising tool to reduce disease and pest incidence. | Prisca Meyer Bram Van de Poel Barbara De Coninck | 2021 | Horticulture Research2021，8，1： | 2 |
| 4 | Alteration of dorsal root ganglion P2X3 receptor expression and function following spinal nerve ligation in the rat显示文摘 | Karen Kage Wende Niforatos Chang Z. Zhu Kevin J. Lynch Prisca Honore Michael F. Jarvis | 2002 | Experimental Brain Research2002，，4： | 1 |
| 5 | Examining the cost effectiveness of interventions to promote the physical health of people with mental health problems:a systematic review显示文摘 | A-La Park David McDaid Prisca Weiser Carolin Von Gottberg | 2013 | BMC Public Health2013，，13： | 1 |
| 6 | Tumor-infiltrating dendritic cells are potent antigen presenting cells able to activate T cells and mediate tumor rejection显示文摘 | Olivier PS Prisca S Emmanuel C | 2006 | J Immumol2006，176，1： | 1 |
| 7 | Influence of fermentation medium composition on physicochemical surface properties of Lactobacillus acidophilus显示文摘 | Prisca SZ Dillmann ML Nicola DA | | 0，，12： | 1 |
| 8 | Syllable structure and sonority in language inventory and aphasic neologisms显示文摘 | Prisca Stenneken Roelien Bastiaanse Walter Huber Arthur M. Jacobs | 2005 | Brain and Language2005，，2： | 1 |
| 9 | ( l )-Phenylglycine, but not necessarily other α 2 δ subunit voltage-gated calcium channel ligands, attenuates neuropathic pain in rats显示文摘 | James J. Lynch Prisca Honore David J. Anderson William H. Bunnelle Kathleen H. Mortell Chengmin Zhong Carrie L. Wade Chang Z. Zhu Hongyu Xu Kennan C. Marsh Chih-Hung Lee Michael F. Jarvis Murali Gopalakrishnan | 2006 | Pain2006，，1： | 1 |
| 10 | Influence of fermentation medium composition on physicochemical surface properties of Lactobacillus acidophilus显示文摘 | Prisca S Z Dillmann M L Nicola D A | 2005 | AEM2005，71，12： | 1 |
| 11 | Influence of Fermentation Medium Composition on Physicochemical显示文摘 | Prisca Scha r-Zammaretti Marie-Lise Dillmann Nicola DAmico | 2005 | Applied and Environmental Microbiology2005，71，12： | 1 |
| 12 | Tumor - infiltrating dendritic cells are potent antigen presenting cells able to activate T ceils and mediate tumor rejection 显示文摘 | Olivier PS Prisca S Emmanuel C | 2006 | J Immumol2006，176，1： | 1 |
| 13 | Elevated serum uric acid levels are associated with diastolic dysfunction in patients with dilated cardiomyopathy显示文摘 | Mariantonietta Cicoira Luisa Zanolla Andrea Rossi Giorgio Golia Lorenzo Franceschini Giovanna Brighetti Prisca Zeni Piero Zardini | 2002 | American Heart Journal2002，，6： | 1 |
| 14 | AB045. Prognostic significance and characterization of small epithelioid cell population in uveal melanoma显示文摘Background:Uveal melanoma(UM)is a malignant neoplasia that is composed of two main types of cells:spindle and epithelioid.There is a subset of neoplastic small epithelioid cells located predominantly in the infiltrative tumor margins or surrounding blood vessels.The aim of this study is to characterize and evaluate the correlation between the presence of these small epithelioid cells and clinical outcome.Methods:The clinical-pathological features of 70 UM patients were evaluated.The presence of small epithelioid cells was quantified based on percentage of tumor volume,and they were characterized using melanocytic markers(HMB-45,Melan A and SOX-10),stem cell markers(CD133,CD24 and CD38),and T cell lymphocytes(CD3).Univariate and multivariate analyses were conducted.Clinical follow up was available for all patients.Results:The ratio of small epithelioid cell components of all 70 tumors ranged from 0%to 30%(median,1%).Thirty-nine tumors(55.7%)had areas with small epithelioid cells.Univariate analysis showed that mixed versus spindle cell,higher lymphocytic infiltration,macrophage infiltration,ciliary body involvement,and>5%of small epithelioid cell component had a significant negative impact on metastasis-free survival.Small epithelioid cell component>5%was present in 24 cases(34.3%).Of these,three were classified as spindle and 21 were mixed.Multivariate analysis revealed that a>5%small cell component was the most significant morphological adverse prognostic factor.Moreover,the small epithelioid cells were negative for HMB45,stem cell markers and CD3,and focally and weakly positive for MELAN A and SOX10.Conclusions:A high small epithelioid cell component is a strong negative prognostic indicator in patients with UM. | Prisca Bustamante Pablo Zoroquiain Evangelina Esposito Ciro Garcia Maria A.Saornil Wiliam April Miguel Burnier | 2018 | Annals of Eye Science2018，，1： | 0 |
| 15 | Cardiopulmonary Response to Exercise at High Altitude in Adolescents with Congenital Heart Disease显示文摘Objective:To extend our knowledge on tolerance of acute high-altitude exposure and hemodynamic response to exercise in adolescents with congenital heart disease(AscCHD)without meaningful clinical or functional restriction.Methods:A symptom limited cardiopulmonary exercise stress test and a non-invasive cardiac output measurement during steady state exercise were performed at 540 m and at 3454 m a.s.l.Symptoms of acute mountain sickness were noted.Results:We recruited 21 healthy controls and 16 AscCHD(59%male,mean age 14.7±1.1 years).Three subjects(2 controls,1 AscCHD)presented light symptoms of acute mountain sickness(dizziness and headache).During the symptom limited exercise test at lowland,control subjects showed a significantly higher power to weight index(3.5±0.6 W/kg vs.3.0±0.7 W/kg,p<0.001),heart rate(188.8±10.41/min vs.179.4±13.11/min,p<0.050)and ventilation(92.8±22.9 l/min vs.75.4±18.6 l/min,<0.050).At altitude,power to weight index only remained significantly higher in the control group(2.8±0.6 W/kg vs.2.6±0.6 W/kg,p<0.001).Pulmonary blood flow(PBF)at lowland showed no difference between the control and the AscCHD group,neither at rest(5.4±0.8 l/min vs.5.1±0.9 l/min,p=0.308),nor during the steady state test(10.6±2.4 l/min vs.10.5±2.0 l/min,p=0.825).At high altitude,PBF increased by 110%and 112%,respectively(12.8±2.32 l/min vs.12.5±3.0 l/min;intergroup difference:p=0.986).Conclusions:High altitude exposure was well tolerated in an unselected group of AscCHD.No significant difference in the cardio-pulmonary adaptation to a control group was noted during a steady state exercise.Symptoms of minor acute mountain sickness did occur,which should however not be misinterpreted as signs of hemodynamic maladaptation. | Lukas Minder Markus Schwerzmann Thomas Radtke Hugo Saner Prisca Eser Matthias Wilhelm Jean-Paul Schmid | 2021 | Congenital Heart Disease2021，16，6： | 0 |
| 16 | Effect of Exercise-Based Cardiac Rehabilitation on Cardiorespiratory Fitness in Adults with Congenital Heart Disease显示文摘Background:The purpose of this study was to investigate whether patients with adult congenital heart disease(ACHD)benefit from exercise-based cardiac rehabilitation(CR)short-and long-term with regard to improvement of cardiorespiratory fitness.Methods:Cardiopulmonary exercise tests(CPET)completed by ACHD patients between January 2000 and October 2019 were analysed retrospectively.Linear mixed models were performed for peak oxygen consumption(VO_(2))with patients as random effect and age,sex,disease classification,preceding surgery(≤3 months)and preceding CR(≤4 weeks for short term and>4 weeks for long term)as fixed effects.Results:1056 CPETs of 311 ACHD patients with simple(7),moderate(188)or great(116)complexity heart defects were analysed.The 59 patients who completed a CR(median age 27 yrs,38%females)increased peak VO_(2)from before to after CR by a median of 2.7(IQR–0.6 to 5.5)ml/kg/min.However,in the multivariate mixed model,peak VO_(2)was non-significantly increased short-term after CR(β0.8,95%CI–0.7 to 2.4),not maintained long-term after CR(β0.0,95%CI–1.7 to 1.6)but significantly reduced after surgery(β–5.1,95%CI–7.1 to–3.1).The 20 CR patients after surgery increased their peak VO_(2)by 6.2(IQR 3.6–9.5)ml/kg/min,while the 39 CR patients without preceding surgery increased it by 0.9(IQR–1.5 to 3.1)ml/kg/min.Conclusions:The increase in peak VO_(2)with CR was mainly due to recovery from surgical intervention.The small independent benefit from CR was not maintained long-term,highlighting the potential to improve current CR concepts in ACHD populations. | Prisca Eser Thomas Gruber Thimo Marcin Claudia Boeni Kerstin Wustmann Christina DeLuigi Matthias Greutmann Daniel Tobler Markus Schwerzmann Matthias Wilhelm | 2021 | Congenital Heart Disease2021，16，1： | 0 |
| 17 | 大角度弹性波阻抗(英文)显示文摘弹性波阻抗及相关技术是以二项AVO方程和三项AVO方程为基础的,它的有效性在世界范围内的许多沉积盆地都得到了验证。在过去的几年中,大偏移距的数据采集使得入射角普遍大于30°,因此必须用三项AVO方程来解决储层流体和岩性识别问题。在入射角小于30°时,所有的线性弹性波阻抗方程都能给出可靠的结果,当入射角大于这一角度时,某些非线性弹性波阻抗方程也能给出理想的结果。然而,由非线性弹性波阻抗获得弹性参数并非易事,因为这需要进行一些复杂的数学变换。到目前为止,只有扩展弹性波阻抗能够适用于所有的入射角度,而在sin2θ域还没有一种能够用于大角度的线性弹性波阻抗。本文提出了另外一种线性弹性波阻抗——大角度弹性波阻抗(FEI)。理论模型和实际数据都证明FEI是大角度寻找油气的有力属性。 | Samba Charles Prisca 刘江平 毛茂 Moussounda Kounga Claude | 2011 | 工程地球物理学报2011，8，4： | 0 |
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