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| 1 | Evaluation of free radical scavenging activity of various extracts of leaves from Kedrostis foetidissima(Jacq.)Cogn显示文摘The present study was aimed to investigate the in vitro free radical scavenging activity of various leaf extracts(aqueous,methanol,acetone chloroform and petroleum ether)of Kedrostis foetidissima.In vitro free radical scavenging activities of the extracts were assessed against DPPH and hydroxyl radicals.The metal chelating activity and reducing power ability of the extracts were also determined.The free radical scavenging activity was found to be high in methanolic extract for DPPH and hydroxyl radicals in a concentration dependent manner followed by chloroform,aqueous,acetone and petroleum ether extracts.The metal chelating activity and reducing power ability was also found to be high in methanolic extract.The difference in scavenging potential of the extracts may be due to variation in the percentage of phytoconstituents extracted in various solvents.Thus the result suggests that the methanolic leaf extract of K.foetidissima could serve as a potential source of antioxidants and can be explored as a therapeutic agent in free radical induced diseases.©2015 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved. | Kalaisezhiyen Pavithra Sasikumar Vadivukkarasi | 2015 | Food Science and Human Wellness2015，4，1： | 6 |
| 2 | AFM-compatible microfluidic platform for affinity- based capture and nanomechanical characterization of circulating tumor cells显示文摘Circulating tumor cells(CTCs)carried by the patient’s bloodstream are known to lead to the metastatic spread of cancer.It is becoming increasingly clear that an understanding of the nanomechanical characteristics of CTCs,such as elasticity and adhesiveness,represents advancements in tracking and monitoring cancer progression and metastasis.In the present work,we describe a combined microfluidic–atomic force microscopy(AFM)platform that uses antibody–antigen capture to routinely isolate and nanomechanically characterize CTCs present in blood samples from prostate cancer patients.We introduce the reversible assembly of a microfluidic device and apply refined and robust chemistry to covalently bond antibodies onto its glass substrate with high density and the desired orientation.As a result,we show that the device can efficiently capture CTCs from patients with localized and metastatic prostate cancer through anti-EpCAM,anti-PSA,and anti-PSMA antibodies,and it is suitable for AFM measurements of captured intact CTCs.When nanomechanically characterized,CTCs originating from metastatic cancer demonstrate decreased elasticity and increased deformability compared to those originating from localized cancer.While the average adhesion of CTCs to the AFM tip surface remained the same in both the groups,there were fewer multiple adhesion events in metastatic CTCs than there were in their counterparts.The developed platform is simple,robust,and reliable and can be useful in the diagnosis and prognosis of prostate cancer as well as other forms of cancer. | Muhammedin Deliorman Farhad K.Janahi Pavithra Sukumar Ayoub Glia Roaa Alnemari Samar Fadl Weiqiang Chen Mohammad A.Qasaimeh | 2020 | Microsystems & Nanoengineering2020，6，1： | 2 |
| 3 | Epstein-Barr Virus-Associated Lymphoepithelioma-like Gastric Carcinoma显示文摘 | Herath Chaturika Harshini Pavithra Chetty Runjan | 2008 | Archives of Pathology & Laboratory Medicine2008，，4： | 2 |
| 4 | Lowered expression levels of a tumor suppressor gene — Caveolin-1 within dysregulated gene networks of Fanconi anemia显示文摘 | Pavithra Shyamsunder Prasanna Vidyasekar Akshay Ranjan Shukla Sheila Mohan Rama Shanker Verma | 2013 | Gene2013，，： | 2 |
| 5 | Maternal dietary folate and/or vitamin B12 restrictions alter body composition (adiposity) and lipid metabo- lism in wistar rat offspring 显示文摘 | KUMAR K A LALITHA A PAVITHRA D | 2013 | The Journal of Nutritional Biochemistry2013，24，1： | 1 |
| 6 | Oral lesions among persons with HIV disease with and without highly active antiretroviral therapy in southern India显示文摘 | Umadevi KM Ranganathan K Pavithra S | 2007 | J Oral Pathol Med2007，36，3： | 1 |
| 7 | Contact urticaria to glycolic acid peel显示文摘 | Vishal B Rao SS Pavithra S | 2012 | J Cutan Aesthet Surg2012，5，1： | 1 |
| 8 | Tumor suppressor SMAR1 mediates cyclinD1 repression by recruitment of the SIN3/histone deacetylase 1 complex显示文摘 | RAMPALLI S PAVITHRA L BHATT A | 2005 | Mol Cel Biol2005，25，19： | 1 |
| 9 | Biofilm formation,bacterial adhesion andhost response on polymeric implants-issues and prevention显示文摘 | Pavithra D Doble M | 2011 | JBiomater Sci Polym Ed2011，22，46： | 1 |
| 10 | Oral lesions among persons with HIV disease with and without highly active antiretroviral therapy in southern India 显示文摘 | Umadevi KM Ranganathan K Pavithra S | 2007 | J Oral Pathol Med2007，36，3： | 1 |
| 11 | Maternal dietary folate and/ or vitamin B12 restrictions alter body composition (adiposity) and lipid metabolism in Wistar rat offspring显示文摘 | Kumar KA Lalitha A Pavithra D | 2013 | J Nutr Biochem2013，24，1： | 1 |
| 12 | A New Electrochemical Approach for the Synthesis of Copper-Graphene Nanocomposite Foils with High Hardness显示文摘 | Pavithra C L P Sarada B V Rajulapati K V | 2014 | Scientific reports2014，，04： | 1 |
| 13 | Contact urticaria to glycolic acid peel显示文摘 | Vishal B Rao SS Pavithra S | 2012 | J Cutan Aesthet Surg2012，5，1： | 1 |
| 14 | Biofilm formation,bacterial adhesion and host response on polymeric implants--issues and prevention显示文摘 | Pavithra D M.Doble | | 0，，03： | 1 |
| 15 | A new electrochemical approach for the synthesis of copper- gra- phene nanocomposite foils with high hardness显示文摘 | Pavithra L P Sarada B V Rajulapati K V | 2014 | Scientif ic Reports2014，4，6： | 1 |
| 16 | Tumor suppressor SMAR1 downregnlates Cytokeratin 8 expression by displacing p53 from its cognate site显示文摘 | Pavithra L Singh S Sreenath K | 2009 | Int J Biochem Cell Biol2009，41，4： | 1 |
| 17 | Maternal dietary fo late and/or vitamin b12 restrictions alter body composition (adiposity) and lipid metabolism in wistar rat offspring显示文摘 | Kumar K A Lalitha A Pavithra D | 2013 | J Nutr Biochem2013，24，1： | 1 |
| 18 | HIV-1 integration sites are flanked by potential MARs that alone can act as promoters 显示文摘 | Kulkarni A Pavithra L Rampalli S | 2004 | Biochem Biophys Res Commun2004，322，2： | 1 |
| 19 | Acalyphatorta Leaf Extract as Green Corro- sion Inhibitor for Mild Steel in Hydrochloric Acid Solution 显示文摘 | PAVITHRA M K VENKATARANGAIAH T V PUNITH KU- MAR M K | 2013 | Industrial & Engineering Chemistry Research2013，52，2： | 1 |
| 20 | Determination of solar cell parameters: an analytical approach 显示文摘 | Sharma S K Pavithra D Srinivasamurthy N | 1993 | Journal of Physics D: Applied Physics1993，26，7： | 1 |
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