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74篇 您的检索式:作者名="Paul Harrison"
    题名 作者 年代 出处 被引量
1不同氮磷比对中肋骨条藻和威氏海链藻生长特性的影响显示文摘实验室条件下用不同氮磷摩尔比(4:1,16:1,64:1)的培养液培养中肋骨条藻Skeletonema costatum和威氏海链藻Thalassiosira weissflogii,对它们的比生长率、细胞状态、细胞对外界氮磷营养元素的吸收和细胞内氮磷比的变化进行了研究。结果表明,氮磷比显著影响两种硅藻的生长和生理状态,氮浓度对细胞生长的影响更大。N限制组(N:P=4:1)的比生长率、细胞数量和叶绿素a含量明显低于正常条件和P限制组(N:P=64:1);威氏海链藻生长对N的变化比中肋骨条藻更为敏感,吸收外界无机氮的速率更快。营养盐充足的情况下,水体中藻细胞的氮磷比变化会较小,但由于'奢侈消费'现象的存在,在出现营养盐限制时,细胞的氮磷比组成会跟随环境的氮磷比改变,在氮限制的条件下,细胞的氮磷比会相应减少,而相反在磷限制的条件下,细胞的氮磷比会明显增加。刘皓 高永利 殷克东 袁翔城 徐杰 HARRISON Paul J 2010热带海洋学报2010,29,6:30
2The natural history of nonalcoholic fatty liver disease: a clinical histopathological study显示文摘Stephen A Harrison Sigurd Torgerson Paul H Hayashi 2003The American Journal of Gastroenterology2003,,9:4
3Heparin resistance in severe thermal injury:a prospective cohort study显示文摘Background:Low molecular-weight heparin(LMWH)is routinely administered to burn patients for thromboprophylaxis.Some studies have reported heparin resistance,yet the mechanism(s)and prevalence have not been systematically studied.We hypothesized that nucleosomes,composed of histone structures with associated DNA released from injured tissue and activated immune cells in the form of neutrophil extracellular traps(NETs or NETosis),neutralize LMWH resulting in suboptimal anticoagulation,assessed by reduction in anti-factor Xa activity.Methods:Blood was sampled from>15%total body surface area(TBSA)burn patients receiving LMWH on days 5,10 and 14.Peak anti-factor Xa(AFXa)activity,anti-thrombin(ATIII)activity,cellfree DNA(cfDNA)levels and nucleosome levels were measured.Mixed effects regression was adjusted for multiple confounders,including injury severity and ATIII activity,and was used to test the association between nucleosomes and AFXa.Results:A total of 30 patients with severe burns were included.Mean TBSA 43%(SD 17).Twentythree(77%)patients were affected by heparin resistance(defined by AFXa activity<0.2 IU/mL).Mean peak AFXa activity across samples was 0.18 IU/mL(SD 0.11).Mean ATIII was 81.9%activity(SD 20.4).Samples taken at higher LWMH doses were found to have significantly increased AFXa activity,though the effect was not observed at all doses,at 8000 IU no samples were heparin resistant.Nucleosome levels were negatively correlated with AFXa(r=−0.29,p=0.050)consistent with the hypothesis.The final model,with peak AFXa as the response variable,was adjusted for nucleosome levels(p=0.0453),ATIII activity(p=0.0053),LMWH dose pre-sample(p=0.0049),drug given(enoxaparin or tinzaparin)(p=0.03),and other confounders including severity of injury,age,gender,time point of sample.Conclusions:Heparin resistance is a prevalent issue in severe burns.Nucleosome levels were increased post-burn,and showed an inverse association with AFXa consistent with the hypothesis that they may interfere with the anticoagulant effect of heparin in vivo and contribute to heparin resistance.Accurate monitoring of AFXa activity with appropriate therapy escalation plans are recommended with dose adjustment following severe burn injury.Liam D Cato Benjamin Bailiff Joshua Price Christos Ermogeneous Jon Hazeldine William Lester Gillian Lowe Christopher Wearn Jonathan RB Bishop Janet M Lord Naiem Moiemen Paul Harrison 2021Burns & Trauma2021,9,1:3
4《促学评价的实践研究》述评显示文摘1.引言 《促学评价的实践研究》是由英国伦敦国王学院的教授及研究人员Paul Black,Chris Harrison,Clare Lee,Bethan Marshall以及Dylan Wiliam根据他们历时两年联合48位教师参与的项目研究写出的一本应用性很强的教育评价方面的专著,2003年由Open University Press出版发行。该书出版十多年来一直被视为形成性评价领域的经典之作,学术谷歌显示其引用率高达1105次。本书详细阐述了如何在一所学校或者一个地区推行促学评价的教育革新,利用评价来促进学生学习,这对于当前中国仍处在起步阶段的形成性评价实践具有很强的借鉴意义。高满满 Paul Black Chris Harrison Clare Lee Bethan Marshall Dylan Wiliam 2015外语测试与教学2015,,1:2
5Utility of B-type natriuretic peptide in the diagnosis of congestive heart failure in an urgent-care setting显示文摘Quyen Dao Padma Krishnaswamy Radmila Kazanegra Alex Harrison Rambod Amirnovin Leslie Lenert Paul Clopton Joel Alberto Patricia Hlavin Alan S Maisel 2001Journal of the American College of Cardiology2001,,2:2
6High sensitivity mapping of methylated cytosines显示文摘Clark SJ Harrison J Paul CL 0,,:1
7High sensitivity mapping of methylated cytosines 显示文摘Clark SJ Harrison J Paul CL 1994Nucleic Acids Res1994,22,15:1
8Inflammation, Immunity, and Hypertension显示文摘David G. Harrison Tomasz J. Guzik Heinrich E. Lob Meena S. Madhur Paul J. Marvar Salim R. Thabet Antony Vinh Cornelia M. Weyand 2011Hypertension2011,,2:1
9The Caesura: remarks on Wittgenstein’s interruption of theory, or, why practices elude explanation显示文摘Paul Harrison 2002Geoforum2002,,:1
10Induction of tumor-specific T-cell responses by vaccination with tumor lysate-loaded dendritic cells in colorectal cancer patients with carcinoembryonic-antigen positive tumors显示文摘Ayala Tamir Ernesto Basagila Arash Kagahzian Long Jiao Steen Jensen Joanna Nicholls Paul Tate Gordon Stamp Farzin Farzaneh Phillip Harrison Hans Stauss Andrew J. T. George Nagy Habib Robert I. Lechler Giovanna Lombardi 2007Cancer Immunology Immunotherapy2007,,12:1
11Phytoplankton Biomass and Production in Subtropical Hong Kong Waters: Influence of the Pearl River Outflow显示文摘Alvin Y. T. Ho Jie Xu Kedong Yin Yuelu Jiang Xiangcheng Yuan Lei He Donald M. Anderson Joseph H. W. Lee Paul J. Harrison 2010Estuaries and Coasts2010,,1:1
12High sensitivity mapping of methylated cytosines 显示文摘Clark SJ Harrison J Paul CL 1994Nucleic Acids Res1994,22,15:1
13High sensitivity mapping of methylated cytosines显示文摘Clark S J Harrison J Paul C L 1994Nucleic Acids Res1994,22,15:1
14A new look at residential electricity demand using household expenditure data显示文摘Harrison Fell Shanjun Li Anthony Paul 2014International Journal of Industrial Organization2014,,:1
15Toward silicon-based lasers for Terahertz sources显示文摘Lynch S A Paul D J Townsend P Matmon G M Suet Z Kelsall R W Ikonic Z Harrison P Zhang J Noriss D J Cullis A G Pidgeon C R Murzyn P Murdin B Bain M Gamble H S Zhao M Ni W X 0,,06:1
16Cretaceous-Tertiary shortening, basin development, and volcanism in central Tibet 显示文摘Kapp Paul Yin An Harrison T Mark 2005GSA Bulletin2005,117,78:1
17Ammonium and nitrate uptake by Laminaria saccharina and Nereocystis luetkeana originating from a salmon sea cage farm显示文摘Okhyun Ahn Royann J. Petrell Paul J. Harrison 1998Journal of Applied Phycology1998,,4:1
18High sensitivity mapping of methylated cytosines显示文摘Clark SJ Harrison J Paul CL 1994Nucleic Acids Res1994,22,15:1
19量子阱、量子线及量子点显示文摘半导体纳米材料是纳米材料的一个重要组成部分,由于能带工程而实现的半导体超晶格、量子阱、量子线和量子点这类低维结构具有的独特物理性质,使得纳米薄膜、纳米微粒、纳米团簇、纳米量子点等所显示出的新颖的电、磁、光以及力学性质,令它们与电子学、光电子学以及通信技术、计算机技术的发展密切相关。纳米结构的电子和光子器件将成为下一代微电子和光电子器件的核心。Paul Harrison 靳绍巍 2010国外科技新书评介2010,,4:1
20Factors contributing to success in research and publications: insights of influential accounting authors显示文摘Chee W Chow Paul Harrison 1998Journal of Accounting Education1998,,3:1
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