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| 1 | SIMULATION OF MAXIMUM LIGHT USE EFFICIENCY FOR SOME TYPICAL VEGETATION TYPES IN CHINA显示文摘Maximum light use efficiency (εmax) is a key parameter for the estimation of net primary pro-ductivity (NPP) derived from remote sensing data. There are still many divergences about its value for each vegetation type. The εmax for some typical vegetation types in China is simulated using a modi-fied least squares function based on NOAA/AVHRR remote sensing data and field-observed NPP data. The vegetation classification accuracy is introduced to the process. The sensitivity analysis of εmax to vegetation classification accuracy is also conducted. The results show that the simulated values of εmax are greater than the value used in CASA model, and less than the values simulated with BIOME-BGC model. This is consistent with some other studies. The rela-tive error of εmax resulting from classification accuracy is ?5.5%―8.0%. This indicates that the simulated values of εmax are reliable and stable. | ZHU Wenquan PAN Yaozhong HE Hao YU Deyong HU Haibo | 2006 | Chinese Science Bulletin2006，51，4： | 61 |
| 2 | Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier显示文摘AIM To investigate whether gut microbiota metabolite sodium butyrate(Na B)is an effective substance for attenuating non-alcoholic fatty liver disease(NAFLD)and the internal mechanisms.METHODS Male C57BL/6J mice were divided into three groups,normal control were fed standard chow and model group were fed a high-fat diet(HFD)for 16 wk,the intervention group were fed HFD for 16 wk and treated with Na B for 8 wk.Gut microbiota from each group were detected at baseline and at 16 wk,liver histology were evaluated and gastrointestinal barrier indicator such as zonula occluden-1(ZO-1)were detected by immunohistochemistry and realtime-PCR,further serum or liver endotoxin were determined by ELISA and inflammation-or metabolism-associated genes were quantified by real-time PCR.RESULTS Na B corrected the HFD-induced gut microbiota imbalance in mice,while it considerably elevated the abundances of the beneficial bacteria Christensenellaceae,Blautia and Lactobacil us.These bacteria can produce butyric acid in what seems like a virtuous circle.And butyrate restored HFD induced intestinal mucosa damage,increased the expression of ZO-1 in small intestine,further decreased the levels of gut endotoxin in serum and liver compared with HF group.Endotoxin-associated genes such as TLR4 and Myd88,pro-inflammation genes such as MCP-1,TNF-α,IL-1,IL-2,IL-6 and IFN-γin liver or epididymal fat were obviously downregulated after Na B intervention.Liver inflammation and fat accumulation were ameliorated,the levels of TG and cholesterol in liver were decreased after Na B intervention,NAS score was significantly decreased,metabolic indices such as FBG and HOMA-IR and liver function indicators ALT and AST were improved compared with HF group.CONCLUSION Na B may restore the dysbiosis of gut microbiota to attenuate steatohepatitis,which is suggested to be a potential gut microbiota modulator and therapeutic substance for NAFLD. | Da Zhou Qin Pan Feng-Zhi Xin Rui-Nan Zhang Chong-Xin He Guang-Yu Chen Chang Liu Yuan-Wen Chen Jian-Gao Fan | 2017 | World Journal of Gastroenterology2017，23，1： | 77 |
| 3 | Restoring urbanization process in China in the 1990s by using non-radiance-calibrated DMSP/OLS nighttime light imagery and statistical data显示文摘Since current administrative unit-based urban land area statistical data in China lack enough spatial information, the urbanization process re- search at large scale cannot be effectively supported. Based on the current administrative unit-based urban land area statistical data in China, a new approach to quickly and cheaply derive urban land information from the non-radiance-calibrated Defense Meteoro- logical Satellite Program/ Operational Linescan Sys- tem (DMSP/OLS) nighttime light imagery is pre- sented in this paper. With the new approach, the ur- ban pattern information in China in 1992, 1996 and 1998 was derived with the urbanization processes in China in the 1990s restored by using the non-ra- diance-calibrated DMSP/OLS nighttime imagery. The accuracy assessment based on the statistical data showed that the relative error between the derived total urban land area and the statistical data at na- tional scale was less than 2% in 1992, and less than 1% in 1996 and 1998, and the maximum relative er- ror at province scale do not exceed 10% with most of the provinces less than 3%. In addition, the urban patterns derived from the high-resolution Landsat TM imagery were compared with those from the DMSP/ OLS data. The results showed that the urban pattern characteristics derived from DMSP/OLS were basi-cally coincident with those from TM imagery with the total accuracy of about 80%. Thus it can be seen that our restored urbanization process in China in the 1990s by using the non-radiance DMSP/OLS night- time imagery can be accepted and can represent the actual urban development in China at that time on the whole. | HE Chunyang SHI Peijun LI dinggang CHEN din PAN Yaozhong LI ding ZHUO Li Ichinose Toshiaki | 2006 | Chinese Science Bulletin2006，51，13： | 55 |
| 4 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 5 | Mortality and Morbidity of Extremely Low Birth Weight Infants in the Mainland of China: A Multi-center Study显示文摘 | Hui-Jia Lin Li-Zhong Du Xiao-Lu Ma Li-Ping Shi Jia-Hua Pan Xiao-Mei Tong Qiu-Ping Li Jian-Guo Zhou Bing Yi Ling Liu Yun-Bing Chen Qiu-Fen Wei Hui-Qing Wu Mei Li Cui-Qing Li Xi-Rong Gao Shi-Wen Xia Wen-Bin Li Chao-Ying Ya Ling He Kun Liang Xiao-Yu Zhou Shu-Ping Han Qin Lyu Yin-Ping Qiu Wen Li Dong-Mei Chen Hong-Ru Lu Xiao-Hong Liu Hong Liu Zhen-Lang Lin Li Liu Jia-Jun Zhu Hong Xiong Shao-Jie Yue Si-Qi Zhuang | 2015 | Chinese Medical Journal2015，，20： | 49 |
| 6 | Recovery of Iron From High-Iron Red Mud by Reduction Roasting With Adding Sodium Salt显示文摘Red mud is the waste generated during aluminum production from bauxite, containing lots of iron and other valuable metals. In order to recover iron from red mud, the technology of adding sodium carbonate-reduction roasting-magnetic separation to treat high-iron red mud was developed. The effects of sodium carbonate dosage, reduction temperature and reduction time on the qualities of final product and the phase transformations in reduction process were discussed in detail. The results showed that the final product (mass percent), assaying Fe of 90.87% and Al2O3 of 0.95% and metallization degree of 94.28% was obtained at an overall iron recovery of 95.76% under the following conditions of adding 8% sodium carbonate, reduction roasting at 1 050 ℃ for 80 min and finally magnetic separation of the reduced pellets by grinding up to 90% passing 0.074 mm at magnetic field intensity of 0.08 T. The XRD (X-ray diffraction) results indicated that the iron oxides were transformed into metallic iron. Most of aluminum mineral and silica mineral reacted with sodium carbonate during the reduction roasting and formed nonmagnetic materials. | ZHU De-qing, CHUN Tie-jun, PAN Jian, HE Zhen (School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, Hunan, China) | 2012 | Journal of Iron and Steel Research(International)2012，19，8： | 38 |
| 7 | Kappa coefficient: a popular measure of rater agreement显示文摘 | Wan TANG Jun HU HuiZHANG Pan WU Hua HE | 2015 | 上海精神医学2015，27，1： | 37 |
| 8 | Effects of citrus tree-shape and spraying height of small unmanned aerial vehicle on droplet distribution显示文摘In order to explore the droplet penetration of spraying with unmanned aerial vehicle(UAV)on citrus trees with different shapes,the tests were carried out at different working heights.The material was five years old Cocktail grapefruit(Citrus paradisi cv.Cocktail)grafted on Trafoliata(Poncirus trifoliata L.Raf.)and the type of UAV sprayer used was the 3W-LWS-Q60S.A solution of 300 times Ponceau 2R diluents liquid instead of pesticide was used for citrus fields spraying and the droplets were collected by paper cards.Droplets deposition parameters were extracted and analyzed using digital image processing after scanning the cards.The results showed that:1)For the trees with round head shape canopy,the droplet depositions of the upper,middle and lower layers had a significant difference at 0.05 level.The droplet deposition had the best effect when the working height was 1.0 m,where the average droplet deposition densities were 39.97 droplets/cm2 and the average droplet size was 0.30 mm,but the droplet coverage(3.19%)was lower than that at the working height of 1.5 m(4.27%).2)Under three different working heights of UAV,the tree with open center shape can obtain higher droplet deposition density at all three layers than that with the round head shape canopy.It was especially prominent when the working height was 1.0 m,as the middle layer increased by 49.92%.However,the higher range of droplet deposition density meant larger fluctuation and dispersion.3)The open center shape canopy and the 1.0 m working height obviously improved the droplet coverage rate and droplet density in the citrus plant.For these parameters of open center shape citrus tree,there was no obvious difference in the front and rear direction,but in the left and middle part of the tree crown,the difference reached a 0.05 significant level.Considering droplet deposition characteristics and the spray uniformity,the UAV performed better when working on open center shape plants at a 1.0 m working height. | Zhang Pan Deng Lie Lyu Qiang He Shaolan Yi Shilai Liu Yande Yu Yongxu Pan Haiyang | 2016 | International Journal of Agricultural and Biological Engineering2016，9，4： | 37 |
| 9 | Fecal microbiota transplantation cured epilepsy in a case with Crohn's disease: The first report显示文摘Fecal microbiota transplantation(FMT)is a promising strategy that involves reconstruction of gut microbiota.Recently,it has been considered as a treatment of Crohn’s disease(CD)and certain neurological diseases.Here,to the best of our knowledge,we report the first case that used FMT to achieve remission of intestinal and neurological symptoms in a girl with CD and a 17-year history of epilepsy.During the 20 mo of follow-up,FMT has proved its efficacy in preventing relapse of seizures after withdrawing the antiepileptic drugs.Furthermore,this finding highlights the role of microbiota-gut-brain axis and inspires a novel treatment for epilepsy through remodeling gut microbiota. | Zhi He Bo-Ta Cui Ting Zhang Pan Li Chu-Yan Long Guo-Zhong Ji Fa-Ming Zhang | 2017 | World Journal of Gastroenterology2017，23，19： | 37 |
| 10 | Application of surface-enhanced laser desorption/ionization time-of-flight-based serum proteomic array technique for the early diagnosis of prostate cancer显示文摘瞄准:由蛋白质薄片和生物信息学识别前列腺癌症(PCa ) 的浆液简历标记。方法:从 83 个 PCa 病人和 95 个健康的人的浆液样品从在长春屏蔽的一个团被拿,中国。蛋白质介绍用提高表面的激光解吸附作用 / 电离 time-of-flight 团分光术(SELDI-TOF MS ) 被执行。系列的数据用二个生物信息学工具被分析。结果:十八浆液微分蛋白质与控制组相比在 PCa 组被识别(P <
0.01 ) 。在在 PCa 组的更低的浆液水平在更高的浆液水平和 14 蛋白质有四蛋白质。使用了一个八蛋白质的集体模式的一个决定树分类算法被开发正确地分类样品。92.0% 的敏感和为学习组的 96.7% 的特性被比较 PCa 和控制组获得。结论:我们识别了 PCa 的新浆液简历标记。SELDI-TOF MS 结合了树分类算法将为 PCa 的早诊断提供一条高度精确、创新的途径的一个决定。 | Yu-Zhuo Pan Xue-Yuan Xiao Dan Zhao Guo-Yi Ji Yang Li Bao-Xue Yang Da-Cheng He Xue-Jian Zhao | 2006 | Asian Journal of Andrology2006，8，1： | 32 |
| 11 | cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions显示文摘癌症房间被知道经历新陈代谢的 reprogramming 然而,支撑幸存和快速的增长 oncogenic 损害怎么在各种各样的强调条件下面协调新陈代谢的开关,尚待充分被阐明。这里,我们显示出葡萄糖或夫酸安的那剥夺,为癌症房间的二主要营养来源,被伴随由的戏剧性地激活的丝氨酸生合成小径(SSP ) 提高了 cMyc 表示。我们进一步鉴别那 cMyc 刺激了 SSP 激活由 transcriptionally 多重 SSP 酶的 upregulating 表示。而且,我们证明 cMyc 便于的 SSP 激活导致了提高的谷胱甘肽(GSH ) 生产,房间周期前进和 nucleic 酸合成,它在剥夺营养素的条件下面特别为房间幸存和增长是必要的。我们进一步揭开了那 phosphoserine 磷酸酶( PSPH ), SSP 小径的最后的限制率的酶,在 vitro 并且在 vivo 为 驾驶cMyc 的癌症前进是批评的,并且重要地, PSPH 的异常表示高度在 hepatocellular 与死亡被相关癌( HCC )病人,一般来说建议在这 调整cMyc 的酶,或 SSP 激活之间的一种潜在的原因的关系,并且癌症开发。一起拿,我们的结果表明 cMyc 的那异常表情导致提高的 SSP 激活,新陈代谢的开关的必要部分,在剥夺营养素的条件下面便于癌症前进。 | Linchong Sun Libing Song Qianfen Wan Gongwei Wu Xinghua Li Yinghui Wang Jin Wang Zhaoji Liu Xiuying Zhong Xiaoping He Shengqi Shen Xin Pan Ailing Li Yulan Wang Ping Gao Huiru Tang Huafeng Zhang | 2015 | Cell Research2015，25，4： | 33 |
| 12 | Land use changes and their relations with carbon cycles over the past 300 a in China显示文摘Land use and land cover in China have changed greatly during the past 300 a, indicated by the rapid abrupt decrease of forest land area and the rapid increase of cropland area, which can affect terrestrial carbon cycle greatly. The first-hand materials are used to analyze main characteristics for land use and land cover changes in China during the study period. The following conclusions can be drawn from this study. The cropland area in China kept increasing from 60.78×106 hm2 in 1661 to 96.09×106 hm2 in 1998. Correspondingly, the forest land area decreased from 248.13×106 hm2 in 1700 to 109.01×106 hm2 in 1949. Affected by such changes, the terrestrial ecosystem carbon storage decreased in the mean time. Car-bon lost from land use and land cover changes mainly consist of the loss from vegetation biomass and soil. In the past 300 a, about 3.70 PgC was lost from vegetation biomass, and emissions from soil ranged from 0.80 to 5.84 PgC. The moderate evaluation of soil losses was 2.48 PgC. The total loss from vegetation and soil was between 4.50 and 9.54 PgC. The moderate and optimum evaluation was 6.18 PgC. Such carbon losses distribution varied spatially from region to region. Carbon lost more significantly in Northeast China and Southwest China than in other regions, because losses of forest land in these two regions were far greater than in the other regions during the past 300 a. And losses of carbon in the other regions were also definite, such as Inner Mongolia, the western part of South China, the Xinjiang Uygur Autonomous Region, and the Qinghai-Tibet Plateau. But the carbon lost very little from the traditional agricultural regions in China, such as North China and East China. Studies on the relationship between land use and land cover change and carbon cycle in China show that the land use activities, especially those related to agriculture and forest management, began to affect terrestrial carbon storage positively in recent years. | GE QuanSheng DAI JunHu HE FanNeng PAN Yuan WANG MengMai | 2008 | Science China Earth Sciences2008，51，6： | 30 |
| 13 | Meta-analysis comparison of endoscopic papillary balloon dilatation and endoscopic sphincteropapillotomy显示文摘AIM: To assess endoscopic papillary balloon dilatation (EPBD) and endoscopic sphincteropapillotomy (EST) for common bile duct (CBD) stone removal using a meta-analysis. METHODS: Randomized controlled trials published from 1990 to 2012 comparing EPBD with EST for CBD stone removal were evaluated. This meta-analysis was performed to estimate short-term and long-term com-plications of these two treatments. The fixed random effect model or random effect model was established to analysis the data. Results were obtained by analyz-ing the relative risk, odds ratio, and 95%CI for a given comparison using RevMan 5.1. Statistical significance was defined asP < 0.05. Risk of bias was evaluated us-ing a funnel plot. RESULTS: Of the 1975 patients analyzed, 980 of them were treated with EPBD and 995 were treated with EST. Of the patient population, patients in the EPBDgroup were younger (OR=-1.16, 95%CI:-1.49 to 0.84, P<0.01). There were no significant differences in gender proportion, average size of stones, number of gallstones, previous cholecystectomy, the incidence of duodenal diverticulum, CBD diameter or the total follow-up time between EST and EPBD groups. Com-pared with EST, the total stone clearance in the EPBD group decreased (OR=0.64, 95%CI: 0.42 to 0.96,P=0.03), the use of stone extraction baskets significantly increased (OR=1.91, 95%CI: 1.41 to 2.59, P<0.01), and the incidence of pancreatitis significantly increased (OR=2.79, 95%CI: 1.74 to 4.45, P<0.0001). The incidence of bleeding (OR=0.12, 95%CI: 0.04 to 0.34, P<0.01) and cholecystitis (OR=0.41, 95%CI: 0.20 to 0.84, P=0.02) significantly decreased. The stone re-currence rate also was significantly reduced in EPBD (OR=0.48, 95%CI: 0.26 to 0.90, P=0.02). There were no significant differences between the two groups with the incidence of stone removal at first attempt, hours of operation, total short-term complications and infection, perforation, or acute cholangitis. CONCLUSION: Although the incidence of pancreatitis was higher, the overall stone clearance rate and risk of bleeding was lower with EPBD compared to EST. | Hong-Chuan Zhao Liang He Da-Chen Zhou Xiao-Ping Geng Fa-Ming Pan | 2013 | World Journal of Gastroenterology2013，19，24： | 27 |
| 14 | Construction of a cucumber genetic linkage map with SRAP markers and location of the genes for lateral branch traits显示文摘Using SRAP (sequence-related amplified polymorphism) markers a genetic linkage map of cucumber was constructed with a population consisting of 138 F2 individuals derived from a cross of the two cucumber lines, S06 and S52. In the survey of parental polymorphisms with 182 primer combinations, 64 polymorphism-revealing primer pairs were screened out, which generated totally 108 polymorphic bands with an average of 1.7 bands per primer pair and at most 6 bands from one primer pair. The constructed molecular linkage map included 92 loci, distributed in seven linkage groups and spanning 1164.2 cM in length with an average genetic distance of 12.6 cM between two neighboring loci. Based on this linkage map, the quantitative trait loci (QTL) for the lateral branch number (lbn) and the lateral branch average length (lbl) in cucumber were identified by QTLMapper1.6. A major QTL lbn1 located between ME11SA4B and ME5EM5 in LG2 could explain 10.63% of the total variation with its positively effecting allele from S06. A major QTL lbl1 located between DC1OD3 and DC1EM14 in LG2 could account for 10.38% of the total variation with its positively effecting allele from S06. | WANG Gang PAN Junsong LI Xiaozun HE Huanle WU Aizhong CAI Run | 2005 | Science China(Life Sciences)2005，48，3： | 24 |
| 15 | SIMS U-Pb zircon age of a tuff layer in the Meishucun section, Yunnan, southwest China: Constraint on the age of the Precambrian-Cambrian boundary显示文摘Determination of the age of the Precambrian-Cambrian boundary is critical in understanding early evolution of life on Earth. SIMS U-Pb zircon analyses of the Bed 5 tuff layer of the Meishucun section were carried out closely following the guidance of cathodoluminescence images, and the majority of analyses were conducted on the oscillatory zircon grains. Thirteen measurements yield a highly reliable Concordia U-Pb age of 536.7 ± 3.9 Ma for the Bed 5 horizon. A grand mean of 206Pb/238U age of 535.2± 1.7 Ma (MSWD = 0.53) is calculated based on 13 concordant SIMS measurements of this study and 4 nano-SIMS measurements of Sawaki et al., which is the best estimate of the deposition age of the tuff layer within Bed 5 in the Meishucun section. This age has provided a robust age constraint on the significant Precambrian-Cambrian boundary strata in southern China, which independently suggested the placement of the Precambrian-Cambrian boundary at the bottom of the Xiaowaitoushan Member (Marker A). | RiXiang Zhu XianHua Li XianGuang Hou YongXin Pan Fei Wang ChengLong Deng HuaiYu He | 2009 | Science China Earth Sciences2009，52，9： | 24 |
| 16 | Single-incision vs three-port laparoscopic cholecystectomy:Prospective randomized study显示文摘AIM:To compare the clinical outcome of single-inci-sion laparoscopic cholecystectomy(SILC)with threeport laparoscopic cholecystectomy(TPLC). METHODS:Between 2009 and 2011,one hundred and two patients with symptomatic benign gallbladder diseases were randomized to SILC(n=49)or TPLC (n=53).The primary end point was post operative pain score(at 6 h and 7 d).Secondary end points were blood loss,operation duration,overall complications,postoperative analgesic requirements,length of hospital stay,cosmetic result and total cost.Surgical techniques were standardized and all operations were performed by one experienced surgeon,who had performed more than 500 laparoscopic cholecystectomies. RESULTS:One patient in the SILC group required conversion to two-port LC.There were no open conversions or major complications in either treatment groups.There were no differences in terms of esti-mated blood loss(mean±SD,14±6.0 mL vs 15±4.0 mL),operation duration(mean±SD,41.8±17.0 min vs 38.5±22.0 min),port-site complications(contusion at incision:5 cases vs 4 cases and hematoma at inci- sion:2 cases vs 1 case),total cost(mean±SD,12 075 ±1047 RMB vs 11 982±1153 RMB)and hospital stay (mean±SD,1.0±0.5 d vs 1.0±0.2 d),respectively. TPLC had a significantly worse visual analogue pain score at 8 h after surgery(mean±SD,3.5±1.6 vs 2.0 ±1.5),however,the scores were similar on day 7(mean ±SD,2.5±1.4 vs 2.0±1.3).Cosmetic satisfaction, as determined by a survey at 2 mo follow-up favored SILC(mean±SD,8±0.4 vs 6±0.2). CONCLUSION:SILC is a safe and feasible approach in selected patients.The main advantages are a better cosmetic result and less pain. | Ming-Xin Pan Ze-Sheng Jiang Yuan Cheng Xiao-Ping Xu Zhi Zhang Jia-Sheng Qin Guo-Lin He Ting-Cheng Xu Chen-Jie Zhou Hai-Yan Liu Yi Gao | 2013 | World Journal of Gastroenterology2013，19，3： | 24 |
| 17 | Experimental and clinical study of influence of high-frequency electric surgical knives on healing of abdominal incision显示文摘瞄准:在腹壁切口愈合上学习高周波的电的外科的刀的影响。方法:240 只白鼠被划分成 10 (0 ) , 10 (2 ) , 10 (5 ) ,并且 10 (8 ) 组和腹部手术的老鼠模型被分别地使用电的外科的刀和普通口针劝诱。然后,他们分别地被给生理盐水和 0.2 mL 的皮下注射在 10 的集中(2 ) 的埃希氏杆菌属关口 i,葡萄球菌 aureus 和绿脓假单胞菌的量的混合, 10 (5 ) 并且 10 (8 ) 。根据动物实验,经历腹部手术(上面的类型 II ) 的 220 个病人随机被分配进跟随三个组之一:电热刀(EK, 93 个盒子) ,电凝法(EC, 55 个盒子) 并且控制(72 个盒子) 。高周波的电的外科的刀习惯于为在 EK 的血壅滞的腹的纸巾和电凝法组织的 dissect。普通口针和电凝法在 EC 组被使用。普通口针和系住的丝缝线在控制被使用。结果:在除了组 10 的所有组(0 ) ,电的外科的刀做的 incisional 创伤的感染率与普通口针比那显著地高。而且,在组有有效差量 10 (2 ) , 10 (5 ) ,并且 10 (8 )(P<0.05 ) ,然而并非(0 )(P>0.05 ) 在组, 10 在 EK 和 EC 之间组织。临床的研究显示出在控制组在 EK,在 EC 的 11 个盒子(16.36%) 和 2 个盒子(2.86%) 在 16 种情况(17.20%) 中愈合的一处推迟的创伤。在 EK 和控制之间的有效差量组织(chi2 = 8.57, P<0.01 ) ,并且在 EC 和控制组之间(chi2 = 5.66, P<0.05 ) 被观察,然而并非在 EK 和 EC 之间(chi2 = 0.017, P>0.05 ) 。结论:高周波的电的刀可以显著地推迟腹壁切口愈合。它的申请应该被最小化以便减少手术后的复杂并发症的可能性。 | Guang-Wei Ji Yuan-Zhi Wu Xu Wang Hua-Xiong Pan Ping Li Wan-Ying Du Zhi Qi An Huang Li-Wei Zhang Li Zhang Wen Chen Guang-Hua Liu Hui Xu Quan Li Ai-Hua Yuan Xiao-Ping He Guo-Hua Mei | 2006 | World Journal of Gastroenterology2006，12，25： | 23 |
| 18 | Rutaecarpine ameliorates hyperlipidemia and hyperglycemia in fat-fed, streptozotocin-treated rats via regulating the IRS-1/PI3K/Akt and AMPK/ACC2 signaling pathways显示文摘瞄准:我们显示出从 Benth (吴·竹·尤) 支持的中国植物茱萸 rutaecarpa (法) 的弄干的水果提取的那 rutaecarpine 在胰岛素抵抗的主要骨胳的肌肉房间的葡萄糖消费和反煽动性的 cytokine 表示。在我们调查了 rutaecarpine 是否改善了的这研究,在老鼠的肥胖侧面,类脂化合物反常,葡萄糖新陈代谢和胰岛素抵抗 hyperlipidemia 和 hyperglycemia.Methods 当模特儿:在高脂肪的节食喂 8 个星期的老鼠,由 streptozotocin 的注射列在后面(30 mg/kg, ip ) 导致 hyperlipidemia 和多糖症。在 streptozotocin 注射以后的一个星期,喂脂肪的、对待 streptozotocin 的老鼠口头上地与 rutaecarpine 被对待(25 mg· kg −1·d−1) 或积极控制药 metformin (250 mg·为 7 个星期的 kg −1·d−1) 。身体重量,内脏的脂肪,血类脂化合物侧面和葡萄糖铺平,胰岛素敏感被测量。煽动性的 cytokines 的浆液层次被分析。IRS-1 和 Akt/PKB phosphorylation, PI3K 和 NF-κ在肝纸巾的 B 蛋白质层次被估计;肝和胰的病理学的变化被检验。葡萄糖举起和 AMPK/ACC2 phosphorylation 在有教养的老鼠被学习在 vitro.Results 的骨胳的肌肉房间:rutaecarpine 或 metformin 的管理显著地减少了肥胖,内脏的胖累积,水消费,和浆液 TC, TG 和 LDL 胆固醇在喂脂肪的、对待 streptozotocin 的老鼠铺平。二药也稀释了多糖症并且提高了胰岛素敏感。而且,二药显著地减少了 NF-κ在肝纸巾的 B 蛋白质层次和血浆 TNF-α, IL-6, CRP 和 MCP-1 铺平,并且改善在肝和胰的病理学的变化。另外,二药增加了 PI3K p85 子单元层次和 Akt/PKB phosphorylation,但是减少在肝纸巾的 IRS-1 phosphorylation。有 rutaecarpine 的有教养的骨胳的肌肉房间的治疗(20-180 μ mol/L ) 或 metformin (20 μ mol/L ) 支持了 AMPK 和 ACC2 的 phosphorylation,并且增加了葡萄糖 uptake.Conclusion:Rutaecarpine 改善在经由调整在骨胳的肌肉在肝和 AMPK/ACC2 发信号小径表明小径的 IRS-1/PI3K/Akt 的喂脂肪的、对待 streptozotocin 的老鼠的 hyperlipidemia 和多糖症。 | Xu-qiang NIE Huai-hong CHEN Jian-yong ZHANG Yu-jing ZHANG Jian-wen YANG Hui-jun PAN Wen-xia SONG Ferid MURAD Yu-qi HE Ka BIAN | 2016 | Acta Pharmacologica Sinica2016，37，4： | 23 |
| 19 | Current status of diagnosis and treatment of bladder cancer in China-Analyses of Chinese Bladder Cancer Consortium database显示文摘Objective:To investigate current status of diagnosis and treatment of bladder cancer in China.Methods:A database was generated by Chinese Bladder Cancer Consortium(CBCC).From January 2007 to December 2012,14,260 cases from 44 CBCC centers were included.Data of diagnosis,treatment and pathology were collected.Results:The average age was 63.5 year-old and most patients were male(84.3%).The most common histologic types were urothelial carcinoma(91.4%),adenocarcinoma(1.8%),and squamous carcinoma(1.9%).According to 1973 and 2004 WHO grading system,42.0%,41.0%,and 17.0% of patients were grade 1,2,and 3,and 16.0%,48.7%,and 35.3% of patients were papillary urothelial neoplasms of low malignant potential,low,and high grade,respectively.Non-muscle invasive bladder cancer(NMIBC)and muscle invasive bladder cancer(MIBC)were 25.2% and 74.1%,respectively(0.8% not clear).Carcinoma in situ was only 2.4%.Most patients were diagnosed by white-light cystoscopy with biopsy(74.3%).Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%,respectively.Diagnostic transurethral resection(TUR)provided detection rate of 16.9%.Most NMIBCs were treated with TUR(89.2%).After initial TUR,2.6%accepted second TUR,and 45.7%,69.9%,and 58.7% accepted immediate,induced,and maintenance chemotherapy instillation,respectively.Most MIBCs were treated with radical cystectomy(RC,59.7%).Laparoscopic RCs were 35.1%,while open RC 63.4%.Extended and standard pelvic lymph node dissection were 7% and 66%,respectively.Three most common urinary diversions were orthotopic neobladder(44%),ileal conduit(31%),and ureterocutaneostomy(23%).Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18%of T3 and T4 patients accepted adjuvant chemotherapy.Conclusion:Disease characteristics are similar to international reports,while differences of diagnosis and treatment exist.This study can provide evidences for revisions of the guideline on bladder cancer in China. | Kaiwen Li Tianxin Lin 无 Wei Xue Xin Mu Enci Xu Xu Yang Fubao Chen Guangyong Li Lulin Ma Guoliang Wang Chaozhao Liang Haoqiang Shi Ming Li Mao Tang Xueyi Xue Yisong Lv Yaoliang Deng Chengyang Li Zhiwen Chen Xiaozhou Zhou Fengshuo Jin Xudong Liu Jinxin Wei Lei Shi Xin Gou Weiyang He Liqun Zhou Lin Cai Baiye Jin Guanghou Fu Xiangbo Kong Hongyan Sun Ye Tian Lang Feng Tiejun Pan Yiyi Wu Dongwen Wang Hailong Hao Benkang Shi Yaofeng Zhu Qiang Wei Ping Han Changli Wu Dawei Tian Zhangqun Ye Zheng Liu Zhiping Wang Junqiang Tian Lin Qi Minfeng Chen Wei Li Jinchun Qi Gongxian Wang Longlong Fu Zhaolin Sun Guangheng Luo Zhoujun Shen Zhaowei Zhu Jinchun Xing Zhun Wu Dong Wei Xin Chen Yanqun Na Hongfeng Guo Chunxi Wang Zhihua Lu Chuize Kong Yang Liu Jin Yang Jianyun Hu Xin Gao Jielin Li Changjun Yin Pu Li Shan Chen Zhen Du Jiongming Li Yongji Yan Xu Zhang Shuang Huang Fangjian Zhou Zhiling Zhang Yinghao Sun Shuxiong Zeng Song Cen Jiaquan Zhou Hanzhong Li Jin Wen Jian Huang | 2015 | Asian Journal of Urology2015，2，2： | 21 |
| 20 | Developing land use scenario dynamics model by the integration of system dynamics model and cellular automata model显示文摘Modeling land use scenario changes and its potential impacts on the structure and function of the ecosystem in the typical regions are helpful to understanding the interactive mechanism between land use system and ecological system. A Land Use Scenario Dynamics (LUSD) model by the integration of System Dynamics (SD) model and Cellular Automata (CA) model is developed with land use scenario changes in northern China in the next 20 years simulated in this paper. The basic idea of LUSD model is to simulate the land use scenario de-mands by using SD model at first, then allocate the land use scenario patterns at the local scale with the considerations of land use suitability, inheritance ability and neighborhood effect by using CA model to satisfy the balance between land use scenario demands and supply. The application of LUSD model in northern China suggests that the model has the ability to reflect the complex behavior of land use system at different scales to some extent and is a useful tool for assessing the potential impacts of land use system on ecological system. In addition, the simulated results also indicate that obvious land use changes will take place in the farming-pastoral zone of northern China in the next 20 years with cultivated land and urban land being the most active land use types. | HE Chunyang, SHI Peijun, CHEN Jin, Li Xiaobing, PAN Yaozhong, LI Jing, LI Yuechen & LI Jinggang Key Laboratory of Environmental Change and Natural Disaster, Ministry of Education of China, Beijing Normal University College of Resources Science & Technology, Beijing Normal University, Beijing 100875, China | 2005 | Science China Earth Sciences2005，48，11： | 21 |
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