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| 1 | Efficiency of HAART in the prevention of mother to children HIV-1 transmission at Saint Camille medical centre in Burkina Faso,West Africa显示文摘Objective:To evaluate efficiency of HAART in the prevention of mother to child HIV transmission.Methods:A longitudinal study was conducted on 1 300 women attending the antenatal service at Saint Camille Medical Centre from September 2010 to July 2011.The HIV status of mothers was determined by rapid tests and EUSA.Discordant results were confirmed by real-time PCR.PCR was used to determine HIV status of children born from HIV-positive mothers.Results:Among 1 300 pregnant women tested for HIV,378 were seropositive.Mothers were predominantly housewives(69.7%),and their mean age was(28.32±0.15) years.The overall prevalence of HIV transmission from mother to child was 4.8%(18/378).This prevalence differed significantly from 0.0%(0/114) to 6.8%(18/264) in children born from mothers under HAART and those with mothers under New Prophylactic Protocol(ACT + 3TC + NVP),respectively(P< 0.01).Children’s mortality rate during the medical follow up was 1.3%(5/378).Among 16 women with HIV dubious status by ELISA,the Real Time PCR confirmed 2/16(12.5%) as HIV positive. Conclusions:The protocol of prevention of mother to children HIV transmission(PMTCT) is effective.The rate of HIV vertical transmission is significantly reduced.Early diagnosis determined by PCR of children born from HIV- positive mother is necessary and recommended in the context of PMTCT in Burkina Faso.We also found that PCR is an effective tool to confirm HIV status in pregnant women. | Laure Stella Ghoma Linguissi Cyrille Bisseye Tani Sagna Bolni Marius Nagalo Djeneba Ouermi Florencia W Djigma Salvatore Pignatelli Joseph D Sia Virginio Pietra Remy Moret Jean Baptiste Nikiema Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，12： | 4 |
| 2 | Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth显示文摘 | Alexander Pietras Amanda M. Katz Elin J. Ekstr?m Boyoung Wee John J. Halliday Kenneth L. Pitter Jillian L. Werbeck Nduka M. Amankulor Jason T. Huse Eric C. Holland | 2014 | Cell Stem Cell2014，，3： | 3 |
| 3 | Antimicrobial resistance of abnormal vaginal discharges microorganisms in Ouagadougou,Burkina Faso显示文摘Objective:To assess the prevalence of bacterial strains and fungal strains infecting the vaginal tract and test their sensitivity to antibiotics in women attending Saint Camille Medical Centre in Ouagadougou.Methods:From January 2008 to December 2009,a total of 2000 vaginal swabs were cultivated for bacterial and fungal identification and isolation.Furthermore,bacterial strains were tested for their susceptibility to several antibiotics used in routine in the centre. Results:The results revealed that microbial isolation and identification was attempted for 1536/2000 sample,a positivity rate of 76.80%.Candida albicans(48.76%),followed by Escherichia coli(16.67%),Streptococcus agalactiae(8-14%) and Staphylococcus aureus(7.55%) were the major agents of genital tract infections in patients.Mycoplasma hominis and Ureaplasma urealyticum combined accounted for less than 7%.Trichomonas vaginalis was identified in 1.04%coses.The antimicrobial tests revealed that the microorganisms developed resistance to several antibiotics including beta lactams.However,antibiotics such as cefamenzol,ciprofloxacin and norfloxacin were still active on these bacteria.Conclusions:The results reveal that many sexually active women are infected by one or more microbial pathogens,probably because of the lock of hygiene or the adoption of some risky behaviors,such as not using condoms or having multiple sexual partners.Efforts should be made to address these points in the country. | Simplice D Karou Florencia Djigma Tani Sagna Christelle Nadembega Moctar Zeba Aboudoulaye Kabre Kokou Anani Djeneba Ouermi Charlemagne Gnoula Virginio Pietra Salvatore Pignatelli Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 2 |
| 4 | Alternative Polyadenylation of the Sense Transcript Controls Antisense Transcription of DELAY OF GERMINATION 1 in Arabidopsis显示文摘 | Justyna Kowalczyk Malgorzata Palusinska Agata Wroblewska-Swiniarska Zbigniew Pietras Lukasz Szewc Jakub Dolata Artur Jarmolowski Szymon Swiezewski | 2017 | Molecular Plant2017，10，10： | 2 |
| 5 | A MyD88-dependent IFNyR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge显示文摘 | Eric M Pietras Lloyd S Miller Carl T Johnson Ryan M O'Connell Paul W Dempsey Genhong Cheng | 2011 | Cell Research2011，21，7： | 2 |
| 6 | The N363S and I559N single nucleotide polymorphisms of the h-GR/NR3C1gene in patients with bronchial asthma显示文摘 | Micha? Panek Tadeusz Pietras Adam Antczak Artur Fabijan Marcelina Przem?cka Pawe? Górski Piotr Kuna Janusz Szemraj | 2012 | International Journal of Molecular Medicine2012，，1： | 2 |
| 7 | The mathematics of Statistical Machine Translation: Parameter Estimation显示文摘 | Brown P F Della Pietra V J Della Pietra S A | 1993 | Compu- tational Linguistics1993，19，2： | 1 |
| 8 | Platelet-derived growth factor D induces cardiac fibrosis and proliferation of vascular smooth muscle ceUs in heartspecific transgenic mice显示文摘 | Pont6n A Folestad EB Pietras K | 2005 | Circ Res2005，97，10： | 1 |
| 9 | A maximum entropy approach to natural language processing显示文摘 | Adam L Berger Stephen A Della Pietra Vincent J Della Pietra | 1996 | Computational Linguistics1996，22，1： | 1 |
| 10 | Foreign Direct Investment and In- vestment under Uncertainty显示文摘 | Pietra Rivoli Engene Salorio | 1996 | Journal of International Business Studie1996，，2： | 1 |
| 11 | A multitargeted, metronomic, and maximum-tolerated dose ' chemo-switch' regimen is anti- angiogenic, producing objective responses and survival benefit in a mouse model of cancer 显示文摘 | Pietras K Hanahan D | 2005 | J Clin Oncol2005，23，5： | 1 |
| 12 | Simultaneous Pancreas-Kidney Transplantation: A Single-Center Experience and Prospective Analysis显示文摘 | M. Rossi Q. Lai G. Spoletini L. Poli F. Nudo S. Ferretti F. Della Pietra F. Pugliese G. Ferretti G. Novelli R. Pretagostini P.B. Berloco | 2008 | Transplantation Proceedings2008，，6： | 1 |
| 13 | Fluvoxamine treatment and D2 receptors:a pet study on OCD drug-naive patients显示文摘 | Moresco R M Pietra L Henin M | 2006 | Neuro- 9sychopharrrmology2006，32，1： | 1 |
| 14 | Carbon-Based Membranes显示文摘 | Tanja Pietra? | 2006 | MRS Bulletin2006，，10： | 1 |
| 15 | Killer cell immunoglobu- lin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition显示文摘 | Saunders PM Pymm P Pietra G | 2016 | J Exp Med2016，213，5： | 1 |
| 16 | The eodon 72 potyrnorphie variants of p53 have markedly different apoptotie potential 显示文摘 | Dumont P Leu JI Della Pietra AC 3rd | 2003 | Nat Genet2003，33，3： | 1 |
| 17 | CD95 ligand induc-es motility and invasiveness of apoptosis-resistant tumor cells 显示文摘 | Barnhart BC Legembre P Pietras E | 2004 | EMBOJ2004，23，15： | 1 |
| 18 | Seroepidemiology of Hepatitis B and C Viruses in the General Population of Burkina Faso显示文摘 | Issoufou Tao Tegwindé R. Compaoré Birama Diarra Florencia Djigma Theodora M. Zohoncon Maléki Assih Djeneba Ouermi Virginio Pietra Simplice D. Karou Jacques Simpore Annarosa Floreani | 2014 | Hepatitis Research and Treatment2014，，： | 1 |
| 19 | Clinical effect of driver mutations of JAK2, CALR, or MPL in primary myelofibrosis 显示文摘 | Rumi E Pietra D Pascutto C | 2014 | Blood2014，124，7： | 1 |
| 20 | Effect of platelet derived growth factor receptor beta inhibition with STI571 on radioimmunotherapy显示文摘 | BARANOWSKA KORTYLEWICZ J ABE M PIETRAS K | 2005 | Cancer Res2005，65，17： | 1 |
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