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| 1 | Efficiency of HAART in the prevention of mother to children HIV-1 transmission at Saint Camille medical centre in Burkina Faso,West Africa显示文摘Objective:To evaluate efficiency of HAART in the prevention of mother to child HIV transmission.Methods:A longitudinal study was conducted on 1 300 women attending the antenatal service at Saint Camille Medical Centre from September 2010 to July 2011.The HIV status of mothers was determined by rapid tests and EUSA.Discordant results were confirmed by real-time PCR.PCR was used to determine HIV status of children born from HIV-positive mothers.Results:Among 1 300 pregnant women tested for HIV,378 were seropositive.Mothers were predominantly housewives(69.7%),and their mean age was(28.32±0.15) years.The overall prevalence of HIV transmission from mother to child was 4.8%(18/378).This prevalence differed significantly from 0.0%(0/114) to 6.8%(18/264) in children born from mothers under HAART and those with mothers under New Prophylactic Protocol(ACT + 3TC + NVP),respectively(P< 0.01).Children’s mortality rate during the medical follow up was 1.3%(5/378).Among 16 women with HIV dubious status by ELISA,the Real Time PCR confirmed 2/16(12.5%) as HIV positive. Conclusions:The protocol of prevention of mother to children HIV transmission(PMTCT) is effective.The rate of HIV vertical transmission is significantly reduced.Early diagnosis determined by PCR of children born from HIV- positive mother is necessary and recommended in the context of PMTCT in Burkina Faso.We also found that PCR is an effective tool to confirm HIV status in pregnant women. | Laure Stella Ghoma Linguissi Cyrille Bisseye Tani Sagna Bolni Marius Nagalo Djeneba Ouermi Florencia W Djigma Salvatore Pignatelli Joseph D Sia Virginio Pietra Remy Moret Jean Baptiste Nikiema Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Medicine2012，5，12： | 4 |
| 2 | Antimicrobial resistance of abnormal vaginal discharges microorganisms in Ouagadougou,Burkina Faso显示文摘Objective:To assess the prevalence of bacterial strains and fungal strains infecting the vaginal tract and test their sensitivity to antibiotics in women attending Saint Camille Medical Centre in Ouagadougou.Methods:From January 2008 to December 2009,a total of 2000 vaginal swabs were cultivated for bacterial and fungal identification and isolation.Furthermore,bacterial strains were tested for their susceptibility to several antibiotics used in routine in the centre. Results:The results revealed that microbial isolation and identification was attempted for 1536/2000 sample,a positivity rate of 76.80%.Candida albicans(48.76%),followed by Escherichia coli(16.67%),Streptococcus agalactiae(8-14%) and Staphylococcus aureus(7.55%) were the major agents of genital tract infections in patients.Mycoplasma hominis and Ureaplasma urealyticum combined accounted for less than 7%.Trichomonas vaginalis was identified in 1.04%coses.The antimicrobial tests revealed that the microorganisms developed resistance to several antibiotics including beta lactams.However,antibiotics such as cefamenzol,ciprofloxacin and norfloxacin were still active on these bacteria.Conclusions:The results reveal that many sexually active women are infected by one or more microbial pathogens,probably because of the lock of hygiene or the adoption of some risky behaviors,such as not using condoms or having multiple sexual partners.Efforts should be made to address these points in the country. | Simplice D Karou Florencia Djigma Tani Sagna Christelle Nadembega Moctar Zeba Aboudoulaye Kabre Kokou Anani Djeneba Ouermi Charlemagne Gnoula Virginio Pietra Salvatore Pignatelli Jacques Simpore | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，4： | 2 |
| 3 | Use of Promethee method to determine the best alternative for warehouse storage location assignment显示文摘 | Marcele Elisa Fonana Cristiano Alexandre Virginio Cavalcate | 2014 | International Journal of Advanced Manufacturing Technology2014，70，9： | 1 |
| 4 | Seroepidemiology of Hepatitis B and C Viruses in the General Population of Burkina Faso显示文摘 | Issoufou Tao Tegwindé R. Compaoré Birama Diarra Florencia Djigma Theodora M. Zohoncon Maléki Assih Djeneba Ouermi Virginio Pietra Simplice D. Karou Jacques Simpore Annarosa Floreani | 2014 | Hepatitis Research and Treatment2014，，： | 1 |
| 5 | A set of recombinant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease显示文摘 | Virginio VG Hernandez A Rott MB | 2003 | Clin Exp Immunol2003，132，2： | 1 |
| 6 | Effects of divalent cations,protons and calmidazoliumat at the Rat P2X7 receptor显示文摘 | CHURCH D NORTH R A | 1997 | Neuropharmacology1997，36，9： | 1 |
| 7 | Regulation of P2X7 nucleotide receptor function in human monocytes by extracellular ions and receptor density显示文摘 | CHURCH D NORTH R A | 2001 | Am J Physiol Cell Physiol2001，280，： | 1 |
| 8 | Trinitrophenyl-substituted nucleotides are potent antagonists selective for P2X1, P2X3, and heteromeric P2X2/3 receptors显示文摘 | Virginio C Robertson G Surprenant A North RA | 1998 | Mol Pharmacol1998，53，6： | 1 |
| 9 | Immune responses elicited by Mycoplasma hyopneumoniae recombinant antigens and DNA constructs with potential for use in vaccination a gainst porcine enzootic pneumonia显示文摘 | Virginio V G Gonchoroski T Paes J A | 2014 | Vaccine2014，32，44： | 1 |
| 10 | A set of recombinant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease显示文摘 | Virginio VG Hernandez A Rott MB | 2003 | Clin Exp Immunol2003，132，： | 1 |
| 11 | A set recombinant antigens from Echinococcus granulosus with potential for use in the immunodi- agnosis of human cystic hydatid disease 显示文摘 | Virginio VG Hernandez A Rott MB | 2003 | Clin Exp Immunol2003，132，2： | 1 |
| 12 | A set of recombi- nant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease显示文摘 | Virginio VG Hernandez A Rott MB et d | 2003 | Clin Exp Immunol2003，132，2： | 1 |
| 13 | Excretory/secretory products from in vitro-cultured Echinococcus granulosus protoscole- ces显示文摘 | Virginio VG Monteiro KM Drumond F | 2012 | Mol Biochem Parasito2012，183，1： | 1 |
| 14 | A set of recombinant antigens from Echinococcus granulosus with potential for in the immunodiagnosis of human cystic hydatid disease 显示文摘 | Virginio VG Hernandez A Rott MB | 2003 | Clin Exp Immunol2003，132，2： | 1 |
| 15 | An in vitro methodology for evaluating the mechanical properties of aortic vascular prosthesis 显示文摘 | Quaglini Virginio Villa Tomaso Migliavacca Francesco | 2002 | Artificial Organs2002，26，6： | 1 |
| 16 | Effects of divalent cat- ions, protons and calmidazolium at the rat P2X7 receptor显示文摘 | Virginio C Chureh D North RA | 1997 | Neuropharmacology1997，36，9： | 1 |
| 17 | A set of recombinant antigets from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease显示文摘 | Virginio VG Hernmdez A Rott MB | 2003 | Clin Exp Immunol2003，132，2： | 1 |
| 18 | Characterization of three diaminopyrimidines as potent and selective antagonists of P2X3 and P2X2/3 receptors with in vivo efficacy in a pain model显示文摘 | Ballini E Virginio C Medhurst SJ | 2011 | Br J Pharmaeol2011，163，6： | 1 |
| 19 | An in vitro methodology for evaluating the mechanical properties of aortic vascular prosthesis 显示文摘 | Virginio Q Tomaso V Francesco M | 2002 | Artificial Organs2002，26，6： | 1 |
| 20 | The per- meabilizing ATP receptor, P2X7 cloning and expression of a human cDNA显示文摘 | Rassendren F Buell GN Virginio C | 1997 | J Biol Chem1997，272，9： | 1 |
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