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| 1 | Role of laryngeal mask airway in laparoscopic cholecystectomy显示文摘Laparoscopic cholecystectomy is one of the most commonly performed surgical procedures and the laryngeal mask airway(LMA) is the most common supraglottic airway device used by the anesthesiologists to manage airway during general anesthesia. Use of LMA has some advantages when compared to endotracheal intubation, such as quick and ease of placement, a lesser requirement for neuromuscular blockade and a lower incidence of postoperative morbididy. However, the use of the LMA in laparoscopy is controversial, based on a concern about increased risk of regurgitation and pulmonary aspiration. The ability of these devices to provide optimal ventilation during laparoscopic procedures has been also questioned. The most important parameter to secure an adequate ventilation and oxygenation for the LMA under pneumoperitoneum condition is its seal pressure of airway. A good sealing pressure, not only state correct patient ventilation, but it reduces the potential risk of aspiration due to the better seal of airway. In addition, the LMAs incorporating a gastric access, permitting a safe anesthesia based on these commented points. We did a literature search to clarify if the use of LMA in preference to intubation provides inadequate ventilation or increase the risk of aspiration in patients undergoing laparoscopic cholecystectomy. We found evidence stating that LMA with drain channel achieves adequate ventilation for these procedures. Limited evidence was found to consider these devices completely safe against aspiration. However, we observed that the incidence of regurgitation and aspiration associated with the use of the LMA in laparoscopic surgery is very low. | José M Belena Ernesto Josué Ochoa Mónica Núnez Carlos Gilsanz Alfonso Vidal | 2015 | World Journal of Gastrointestinal Surgery2015，7，11： | 4 |
| 2 | Effectiveness of an intervention for reducing social stigma towards mental illness in adolescents显示文摘AIM: To evaluate the effectiveness of an intervention for reducing social stigma towards mental illness in adolescents. The effect of gender and knowledge of someone with mental illness was measured. METHODS: Two hundred and eighty secondary school students were evaluated using the Community Attitudes towards Mental Illness(CAMI) questionnaire. The schools were randomized and some received the intervention and others acted as the control group. The programme consisted of providing information via a documentary film and of contact with healthcare staff in order to reduce the social stigma within the school environment. RESULTS: The intervention was effective in reducing the CAMI authoritarianism and social restrictiveness subscales. The intervention showed significant changes in girls in terms of authoritarianism and social restrictiveness, while boys only showed significant changes in authoritarianism. Following the intervention, a significant reduction was found in authoritarianism and social restrictiveness in those who knew someone with mental illness, and only in authoritarianism in those who did not know anyone with mental illness. CONCLUSION: The intervention was effective to reduce social stigma towards people with mental illness, especially in the area of authoritarianism. Some differences were found depending on gender and whether or not the subjects knew someone with mental illness. | Regina Vila-Badia Francisco Martínez-Zambrano Otilia Arenas Emma Casas-Anguera Esther García-Morales Raúl Villellas José Ramón Martín María Belén Pérez-Franco Tamara Valduciel Diana Casellas Mar García-Franco Jose Miguel Joaquim Balsera Gemma Pascual Eugènia Julia Susana Ochoa | 2016 | World Journal of Psychiatry2016，6，2： | 4 |
| 3 | Intrinsic subtypes and bladder cancer metastasis显示文摘Recent studies demonstrated that bladder cancers can be grouped into basal and luminal molecular subtypes that possess distinct biological and clinical characteristics.Basal bladder cancers express biomarkers characteristic of cancer stem cells and epithelial-tomesenchymal transition(EMT).Patients with basal cancers tend have more advanced stage and metastatic disease at presentation.In preclinical models basal human orthotopic xenografts are also more metastatic than luminal xenografts are,and they metastasize via an EMT-dependent mechanism.However,preclinical and clinical data suggest that basal cancers are also more sensitive to neoadjuvant chemotherapy(NAC),such that most patients with basal cancers who are aggressively managed with NAC have excellent outcomes.Importantly,luminal bladder cancers can also progress to become invasive and metastatic,but they appear to do so via mechanisms that are much less dependent on EMT and may involve help from stromal cells,particularly cancer-associated fibroblasts(CAFs).Although patients with luminal cancers do not appear to derive much clinical benefit from NAC,the luminal tumors that are infiltrated with stromal cells appear to be sensitive to anti-PDL1 antibodies and possibly other immune checkpoint inhibitors.Therefore,neoadjuvant and/or adjuvant immunotherapy may be the most effective approach in treating patients with advanced or metastatic infiltrated luminal bladder cancers. | David J.McConkey Woonyoung Choi Andrea Ochoa Colin P.N.Dinney | 2016 | Asian Journal of Urology2016，3，4： | 4 |
| 4 | Distributing disciplinarian of ground motion parameters on an earth fissure site during strong earthquakes显示文摘To investigate the distributing disciplinarian of ground motion parameters on the earth fissure site during strong earthquakes,a series of shaking table tests were designed and conducted based on 1:15 scaled models.Test results showed significant differences in the ground motion parameters(including ground motion intensity indices,spectrum characteristics and strong motion duration)between the hanging-wall and footwall caused by the earth fissure.Acceleration response,displacement response and Arias Intensity response on both sides of earth fissure indicated that the earth fissure site on the hanging-wall was destroyed more seriously.The distributing disciplinarian of amplification factors showed clear'hangingwall and footwall effects',which were more remarkable nearby the fissure zones.The low-frequency component of the seismic wave was richer after selectively filtering in the soil medium.By comparing the predominant period and mean period of the hanging-wall and footwall,it was found that vibration frequency on the hanging-wall was greater than that on the footwall.Minimum values of strong motion duration were recorded on the hanging-wall close to the fissure and increased from the fissure to both sides. | Xiong Zhongming Zhang Chao Huo Xiaopeng Chen Xuan J.Jorge Ochoa | 2020 | Earthquake Engineering and Engineering Vibration2020，19，3： | 4 |
| 5 | 16-Year Trends in the Infection Burden for Pacemakers and Implantable Cardioverter-Defibrillators in the United States显示文摘 | Arnold J. Greenspon Jasmine D. Patel Edmund Lau Jorge A. Ochoa Daniel R. Frisch Reginald T. Ho Behzad B. Pavri Steven M. Kurtz | 2011 | Journal of the American College of Cardiology2011，，10： | 3 |
| 6 | Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine and American Society for Parenteral and Enteral Nutrition: Executive Summary*显示文摘 | Robert G. Martindale Stephen A. McClave Vincent W. Vanek Mary McCarthy Pamela Roberts Beth Taylor Juan B. Ochoa Lena Napolitano Gail Cresci | 2009 | Critical Care Medicine2009，，5： | 3 |
| 7 | Increase of Th17 cells in peripheral blood of patients with chronic obstructive pulmonary disease显示文摘 | María Inés Vargas-Rojas Alejandra Ramírez-Venegas Leonardo Limón-Camacho Leticia Ochoa Rafael Hernández-Zenteno Raúl H. Sansores | 2011 | Respiratory Medicine2011，，11： | 2 |
| 8 | Suitability of enzyme activities for the monitoring of soil quality improvement in organic agricultural systems显示文摘 | Roberto García-Ruiz Victoria Ochoa M. Belén Hinojosa Jose Antonio Carreira | 2008 | Soil Biology and Biochemistry2008，，9： | 2 |
| 9 | A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification显示文摘In this paper,we present a disposable,colorimetric,user-friendly and mass-customizable dermal patch for chronological collection and discrete real-time in situ measurement of sweat secretion over a small area of skin.The patch consists of a laminated filter paper patterned into radially arranged channels/fingers with water-activated dyes at their tips.As channels are filled during perspiration,their tips change color once fully saturated,providing easily identifiable levels of water loss which in turn can be mapped to personal dehydration levels.The patch can be manufactured at low cost in a variety of sizes to allow hydration monitoring for individuals participating in activities under different conditions(intensity,temperature,humidity,etc.).Furthermore,we describe an analytical model that enables mass customization of such a flexible wearable system accommodating a broad range of sweat rates and volumes to generate patch designs that are personalized to an individual’s sweat rate,desired time of usage,and the temporal resolution of the required feedback.As a proof-of-concept demonstration,we characterized laser-fabricated patches that cover(7 cm×5 cm)area of skin having various wicking materials,thicknesses(180–540μm),and pore sizes(3–11μm).Tests were conducted at various flow rates simulating different sweating intensities in the range of 1.5–15 mg/cm^(2)/min.Experimental results for the case of a half-marathon runner targeting 90 min of usage and sweating at a rate of 1.5 mg/cm2/min indicated measurement accuracy of 98.3%when the patch is completely filled. | Vaibhav Jain Manuel Ochoa Hongjie Jiang Rahim Rahimi Babak Ziaie | 2019 | Microsystems & Nanoengineering2019，5，1： | 2 |
| 10 | Hedgehog signaling is critical for normal liver regeneration after partial hepatectomy in mice显示文摘 | Bego?a Ochoa Wing‐Kin Syn Igotz Delgado Gamze F. Karaca Youngmi Jung Jiangbo Wang Ana M. Zubiaga Olatz Fresnedo Alessia Omenetti Marzena Zdanowicz Steve S. Choi Anna Mae Diehl | 2010 | Hepatology2010，，： | 2 |
| 11 | 神经痛患者C伤害性感受器的温度依赖性双峰 | Bostock H. Campero M. Serra J. Ochoa J.L. 袁海峰 | 2005 | 世界核心医学期刊文摘(神经病学分册)2005，0，12： | 2 |
| 12 | EUS-guided single-incision needle-knife biopsy: description and results of a new method for tissue sampling of subepithelial GI tumors (with video)显示文摘 | Carlos de la Serna-Higuera Manuel Pérez-Miranda Pilar Díez-Redondo Paula Gil-Simón Teresa Herranz Elena Pérez-Martín C. Ochoa Agustín Caro-Patón | 2011 | Gastrointestinal Endoscopy2011，，3： | 2 |
| 13 | Surgical Management of Hepatocellular Adenoma: Take It or Leave It?显示文摘 | Sung W. Cho MBBS MSc J. Wallis Marsh MD Jennifer Steel PhD Shane E. Holloway MD Jason T. Heckman MD Erin R. Ochoa MD David A. Geller MD T. Clark Gamblin MD MS | 2008 | Annals of Surgical Oncology2008，，10： | 2 |
| 14 | Suitability of enzyme activities for the monitoring of soil quality improvement in organic agricultural systems显示文摘 | Garcia-Ruiz R Ochoa V Hinojosa M B | 2008 | Soil Biology and Biochemistry2008，40，： | 1 |
| 15 | Evaluating distributed generation impacts with a multiobjective index显示文摘 | Ochoa L F Padilha-Feltrin A Harrison G | 2006 | IEEE Trans on Power Del2006，21，3： | 1 |
| 16 | NF-Y and Sp1 are involved in transcriptional regulation of rat SND p102 gene显示文摘 | RODRIGUEZ L OCHOA B MARTINEZ M J | 2007 | Biochem Biophys Res Commun2007，356，1： | 1 |
| 17 | L-arginine availability regu-lates T-lymphocyte cell-cycle progression显示文摘 | Rodriguez P C Quiceno D G Ochoa A C | 2007 | Blood2007，109，4： | 1 |
| 18 | Twent - four hour esophageal pH monitoring in gastroesophgeal reflux显示文摘 | Boix - Ochoa J Lafuente JM Gil - Vernet JM | 1980 | J Pediatr Surg1980，15，： | 1 |
| 19 | Effects of L-arginine on the Proliferation of T lymphocyte subpo-pulations显示文摘 | Ochoa J B Strange J Kearney P | 2001 | J Parenter Enter Nutr2001，25，： | 1 |
| 20 | Bacterial translocation in trauma patients显示文摘 | Peitzman A B Udekwu A O Ochoa J | 1991 | J Trauma1991，31，8： | 1 |
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