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| 1 | Thread-based multiplexed sensor patch for real-time sweat monitoring显示文摘Sensor platforms that exploit the fibrous textile threads as substrates offer great promise since they can be directly sewn,woven or stitched on to any clothing.They can also be placed directly in intimate contact with the skin.In this work,we present a thread-based sensing platform in the form of a multiplexed sensing patch for continuous simultaneous on-skin monitoring of sweat.The patch performs real-time,on-body measurements of important biomarkers present in sweat such as electrolytes(sodium and ammonium ions),metabolites(lactate)and acidity(pH).Flexible threads coated with conductive inks were used as sensing electrodes.Selective potentiometric detection of electrolytes and pH was made possible through ion-selective membrane deposition and pH-sensitive polyaniline coating on threads,respectively.An amperometric enzymatic sensing scheme with lactate oxidase was used for the detection of lactate.An array of the thread sensors is integrated onto a patch with connectivity to a miniaturized circuit module containing a potentiostat,microprocessor and wireless circuitry for wireless smartphone readout.Extensive in vitro validation and an in vivo human pilot study involving a maximal exertion test show the promise of this platform for real-time physiological monitoring of human performance/fitness under stress,as well as diagnostic monitoring through sweat analysis. | Trupti Terse-Thakoor Meera Punjiya Zimple Matharu Boyang Lyu Meraj Ahmad Grace E.Giles Rachel Owyeung Francesco Alaimo Maryam Shojaei Baghini Tad TBrunyé Sameer Sonkusale | 2020 | npj Flexible Electronics2020，4，1： | 1 |
| 2 | Stretchable and durable HD-sEMG electrodes for accurate recognition of swallowing activities on complex epidermal surfaces显示文摘Surface electromyography(sEMG)is widely used in monitoring human health.Nonetheless,it is challenging to capture high-fidelity sEMG recordings in regions with intricate curved surfaces such as the larynx,because regular sEMG electrodes have stiff structures.In this study,we developed a stretchable,high-density sEMG electrode array via layerby-layer printing and lamination.The electrode offered a series of excellent human‒machine interface features,including conformal adhesion to the skin,high electron-to-ion conductivity(and thus lower contact impedance),prolonged environmental adaptability to resist water evaporation,and epidermal biocompatibility.This made the electrode more appropriate than commercial electrodes for long-term wearable,high-fidelity sEMG recording devices at complicated skin interfaces.Systematic in vivo studies were used to investigate its ability to classify swallowing activities,which was accomplished with high accuracy by decoding the sEMG signals from the chin via integration with an ear-mounted wearable system and machine learning algorithms.The results demonstrated the clinical feasibility of the system for noninvasive and comfortable recognition of swallowing motions for comfortable dysphagia rehabilitation. | Ding Zhang Zhitao Chen Longya Xiao Beichen Zhu RuoXuan Wu ChengJian Ou Yi Ma Longhan Xie Hongjie Jiang | 2023 | Microsystems & Nanoengineering2023，9，5： | 0 |
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