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| 1 | Predictors of response to antiviral therapy in patients with chronic hepatitis C from Pakistani population显示文摘背景丙肝病毒(HCV ) 在全世界组成一个主要公共健康问题,特别在开发象巴基斯坦一样的国家。在这研究,我们估计了在长期的丙肝病人的治疗在这研究由性,年龄,和病毒的 load.Methods 分类的干扰素(INF ) 的结果,有遗传型 3 的 750 个 HCV 积极病人被选择,从哪个 616 完成了全部治疗。他们的个人历史,支持处理的 HCV RNA 和浆液丙氨酸 transaminase (中高音) 是 quantified.Patients 与 INF- 2b 的联合治疗被对待 300 万个单位(三次一个星期) 正 ribavirin (1000-1200mg 每天) 为 24 个星期。在 24 个星期以后,他们的 HCV RNA 和浆液中高音水平是从 616 个病人,的 quantified.Results (63.5%) 391 对治疗学的政体(加 ribavirin 的 INF- 2b ) 作出回应。在应答者之中, 27.1% 是男人, 36.4% 是女人。最好的治疗反应在有 Iow 的病人被观察病毒的负担 8 ?????牴湡睳汥 吗?? | Hafsa Aziz Muhammad Amin Athar Shahnaz Murtaza Javaid Irfan Yasir Waheed Iram Bilal Abida Raza | 2011 | Chinese Medical Journal2011，，9： | 6 |
| 2 | Stability analysis of different cotton genotypes under normal and water-deficit conditions显示文摘Cotton plant observes significant reduction in seed cotton yield when subjected to water stress.To find out genotypes having better drought tolerance,seven genotypes of Gossypium hirsutum L.were tested under two moisture levels,i.e.,normal and water deficit stress conditions at five locations of Punjab,Pakistan(Faisalabad,Sahiwal,Vehari,Rahim Yar Khan,and Bahawalpur)in 2013 and 2014.Genotype×environment interaction(GEI)was studied using the genotype main effects and genotype by environment interaction(GGE)biplot and additive main effect and multiplicative interaction analysis.The genotypes G3(7001/11)and G6(FH-942)were stable under normal condition,while under drought condition,the stable genotype was G5(FH-326)when analysed using additive main effects and multiplicative interaction(AMMI)biplot scheme.While GGE biplot analysis on the basis of best performance revealed that under normal condition the genotypes,G1(L-13/10)and G2(FH-2056/10),carrying the common position in biplot.Whereas,under water deficit stress condition,G5 was the best adaptive genotype at all five locations.In the same way,ranking of genotypes showed that the G5 was the ideal genotype under both conditions.So,it is concluded that the genotype G5(FH-326)was found best for water deficit stress condition and can be cultivated under water scarce areas of Punjab. | Muhammad Riaz Jehanzeb Farooq Saghir Ahmed Muhammad Amin Waqas Shafqat Chattha Maria Ayoub Riaz Ahmed Kainth | 2019 | Journal of Integrative Agriculture2019，18，6： | 5 |
| 3 | Composite insulators and their aging: An overview显示文摘The aging (biological deterioration) is a major problem of composite insulators now-a-days. The main thing in aging is to predict how, when and with what speed it occurs and under what conditions it can lead to failure and what overall average expected life of a composite insulator is. For this a lot of researches have been done. This review summarizes the methods of artificial field testing (aging), natural testing, standards the developed for aging, techniques of analysis, results achieved until now about various parameters from various locations, handling guidelines and a conclusion on what is further needed. | Muhammad AMIN Muhammad AKBAR Muhammad SALMAN | 2007 | Science China(Technological Sciences)2007，50，6： | 4 |
| 4 | Optimization of equitable irrigation water delivery for a large-scale rice irrigation scheme显示文摘Equitable water allocation is essential in an irrigation scheme for obtaining potential crop yields from the entire scheme,especially when water supply is inadequate.An optimization model achieved this goal by coupling an optimal water allocation model with available water supply and irrigation water demand for a river-fed rice irrigation system in Malaysia.This model consists of a paddy field water balance module and an optimization module.The outputs from the module are daily irrigation demand and surface runoff,if there is any.The optimization module consists of an objective function,which minimizes water shortage across the scheme area while maintaining equity in water allocation.This model performs optimization subject to several system constraints,and the decision variable of the model is daily releases or supply to the tertiary canals.Performance of this model remained unaffected under different water supply conditions,and the optimization model reliably examined the effects of alternate water allocation and management rules with field information.It improves efficiency and equity in water allocation with respect to crop growth stages and water shortages rather than simply cutting irrigation supply on a proportional basis to overcome water shortages. | Md Rowshon Kamal Muhammad Iqbal Md Abdul Mojid Mohd Amin Mohd Soom Lai Sai Hin | 2018 | International Journal of Agricultural and Biological Engineering2018，11，5： | 3 |
| 5 | Antimicrobial chemical constituents from endophytic fungus Phoma sp.显示文摘Objective:To evaluate the antiniicrobial polenlial of different extracts of the endophytic fungus Phoma sp.and the tentative identification of their active constituents.Methods:The extract and compounds were screened for antimicrobial activity using the Agar Well Diffusion Method.Four compounds were purified using column chromatography and tlieir structures were assigned using~1H and~(13)C NMR spectra,DEPT,2D COSY,HMQC and HMBC experiments.Results:The ethyl acetate fraction of Phoma sp.showed good antifungal,antibacterial,and algicidal properties.One new dihydrofuran derivative,named phomafuranol(1),together with tliree known compounds,phomalacton(2),(3R)-5-hydroxymellein(3)and emodin(4)were isolated from the ethyl acetate fraction of Phoma sp.Preliminary studies indicated that phomalacton(2)displayed strong antibacterial,good antifungal and antialgal activities.Similarly(3R)-5-hydroxymellein(3)and emodin(4)showed good antifungal,antibacterial and algicidal properties.Conclusions:Antimicrobial activities of the ethyl acetate fraction of the endophytic fungus Phoma sp.and isolated compounds clearly demonstrate that Phoma sp.and its active compounds represent a great potential for the food,cosmetic and pharmaceutical industries. | Hidayat Hussain Ines Kock Ahmed Al-Harrasi Ahmed Al-Rawahi Ghulam Abbas Ivan R.Green Afzal Shah Amin Badshah Muhammad Saleem Siegfried Draeger Barbara Schulz Karsten Krohn | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，9： | 3 |
| 6 | Role of platelet-albumin-bilirubin score in predicting re-bleeding after band ligation for acute variceal hemorrhage显示文摘Platelet-albumin-bilirubin(PALBI)score was proposed by Roayaie et al with modification of previously studied albumin-bilirubin score to include platelet as an indicator of portal hypertension in 2015.Predictive value of this score was recently tested by Elshaarawy et al for re-bleeding in patients presenting with acute variceal hemorrhage.We did a similar study at our center(n=170)to look at incidence of re-bleeding after band ligation defined as drop in 2 units of hemoglobin and witnessed melena or hematemesis within 2 wk of the procedure.We calculated PALBI scores for all patients based on lab values prior to the procedure.Of 25.3%had re-bleeding episodes,area under receiver operating characteristic curve for PALBI as predictor of re-bleeding was 0.601(95%confidence interval:0.502-0.699).PALBI score showed moderate accuracy at predicting re-bleeding in our population. | Muhammad S Faisal Tavankit Singh Hina Amin Jamak Modaresi Esfeh | 2020 | World Journal of Hepatology2020，12，10： | 3 |
| 7 | Characteristic spectral studies and in vitro antifungal activity of some Schiff bases and their organotin (Ⅳ) complexes显示文摘The synthesis and in vitro antifungal activity of some Schiff bases and their Sn (Ⅳ) complexes has been tested against plant pathogenic fungi and it is found that they possess excellent fungicidal activity. On the basis of ^1H-, ^13C-,^119Sn NMR-, ^119Sn Mǒssbauer, IR and Elemental analysis the tetrahedral geometry is proposed for the synthesized compounds. | Wajid Rehman Musa Kaleem Baloch Bakhtiar Muhammad Amin Badshah Khalid M.Khan | 2004 | Chinese Science Bulletin2004，49，2： | 3 |
| 8 | 腐植酸施用方法对绿豆产量及其构成因子的影响显示文摘为了探索腐植酸(HA)的施用方法,在白沙瓦开伯尔-普什图省农业大学的农业研究农场内进行了完全随机区组设计试验,并设置3次重复。HA的施用方法分为浸种、叶片喷施和土壤施用3种。HA的施用方法对绿豆单株结荚数、每荚粒数、千粒重和籽粒产量具有显著影响,而对绿豆生物量影响不大。每公顷土地施用3 kg HA能显著提高绿豆结荚率、千粒重和产量;而土壤中加入1 kg/hm^2和2 kg/hm^2 HA,浓度为0、1%、2%的HA浸种和0.01%、0.05%、0.1%的HA叶面喷施3种方法所得到的结果在统计学上相似。由此得出结论:3种施用HA的方法均能显著提高绿豆产量及其构成因子。 | Muhammad Waqas Bashir Ahmad Muhammad Arif Fazal Munsif Abdul Latif Khan Muhammad Amin Sang-Mo Kang Yoon-Ha Kim In-Jung Lee 刘雪娇 茹雪峰 高同国 | 2016 | 腐植酸2016，，6： | 2 |
| 9 | An I/Q mixer with an integrated differential quadrature all-pass filter for on-chip quadrature LO signal generation显示文摘A down-conversion in-phase/quadrature(I/Q) mixer employing a folded-type topology,integrated with a passive differential quadrature all-pass filter(D-QAF),in order to realize the final down-conversion stage of a60 GHz receiver architecture is presented in this work.Instead of employing conventional quadrature generation techniques such as a polyphase filter or a frequency divider for the local oscillator(LO) of the mixer,a passive D-QAF structure is employed.Fabricated in a 65 nm CMOS process,the mixer exhibits a voltage gain of 7-8 dB in an intermediate frequency(IF) band ranging from 10 MHz-1.75 GHz.A fixed LO frequency of 12 GHz is used to down-convert a radio frequency(RF) band of 10.25-13.75 GHz.The mixer displays a third order input referred intercept point(IIP_3) ranging from-8.75 to-7.37 dBm for a fixed IF frequency of 10 MHz and a minimum single-sideband noise figure(SSB-NF) of 11.3 dB.The mixer draws a current of 6 mA from a 1.2 V supply voltage dissipating a power of 7.2 mW. | Najam Muhammad Amin 王志功 李智群 | 2015 | Journal of Semiconductors2015，36，5： | 2 |
| 10 | Serious games in science education:a systematic literature review显示文摘Teaching science through computer games,simulations,and artificial intelligence(AI)is an increasingly active research field.To this end,we conducted a systematic literature review on serious games for science education to reveal research trends and patterns.We discussed the role of virtual reality(VR),AI,and augmented reality(AR)games in teaching science subjects like physics.Specifically,we covered the research spanning between 2011 and 2021,investigated country-wise concentration and most common evaluation methods,and discussed the positive and negative aspects of serious games in science education in particular and attitudes towards the use of serious games in education in general. | Mohib ULLAH Sareer Ul AMIN Muhammad MUNSIF Muhammad Mudassar YAMIN Utkurbek SAFAEV Habib KHAN Salman KHAN Habib ULLAH | 2022 | Virtual Reality & Intelligent Hardware2022，4，3： | 2 |
| 11 | SARS-CoV-2 involvement in central nervous system tissue damage显示文摘As the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)continues to spread globally,it became evident that the SARS-CoV-2 virus infects multiple organs including the brain.Several clinical studies revealed that patients with COVID-19 infection experience an array of neurological signs ranging in severity from headaches to life-threatening strokes.Although the exact mechanism by which the SARS-CoV-2 virus directly impacts the brain is not fully understood,several theories have been suggested including direct and indirect pathways induced by the virus.One possible theory is the invasion of SARS-CoV-2 to the brain occurs either through the bloodstream or via the nerve endings which is considered to be the direct route.Such findings are based on studies reporting the presence of viral material in the cerebrospinal fluid and brain cells.Nevertheless,the indirect mechanisms,including blood-clotting abnormalities and prolonged activation of the immune system,can result in further tissue and organ damages seen during the course of the disease.This overview attempts to give a thorough insight into SARS-CoV-2 coronavirus neurological infection and highlights the possible mechanisms leading to the neurological manifestations observed in infected patients. | Muhammad Ali Haidar Zaynab Shakkour Mohammad Amine Reslan Nadine Al-Haj Perla Chamoun Karl Habashy Hasan Kaafarani Shima Shahjouei Sarah HFarran Abdullah Shaito Esber SSaba Bassam Badran Mirna Sabra Firas Kobeissy Maya Bizri | 2022 | Neural Regeneration Research2022，17，6： | 2 |
| 12 | Mesuaferrea stem bark extract induces apoptosis and inhibits metastasis in human colorectal carcinoma HCT 116 cells, through modulation of multiple cell signalling pathways显示文摘Considering the great potential of natural products as anticancer agents, the present study was designed to explore the molecular mechanisms responsible for anticancer activities of Mesua ferrea stem bark extract against human colorectal carcinoma. Based on MTT assay results, bioactive sub-fraction(SF-3) was selected for further studies using HCT 116 cells. Repeated column chromatography resulted in isolation of less active α-amyrin from SF-3, which was identified and characterized by GC-MS and HPLC methods. α-amyrin and betulinic acid contents of SF-3 were measured by HPLC methods. Fluorescent assays revealed characteristic apoptotic features, including cell shrinkage, nuclear condensation, and marked decrease in mitochondrial membrane potential in SF-3 treated cells. In addition, increased levels of caspases-9 and-3/7 levels were also observed in SF-3 treated cells. SF-3 showed promising antimetastatic properties in multiple in vitro assays. Multi-pathway analysis revealed significant down-regulation of WNT, HIF-1α, and EGFR with simultaneous up-regulation of p53, Myc/Max, and TGF-β signalling pathways in SF-3 treated cells. In addition, promising growth inhibitory effects were observed in SF-3 treated HCT 116 tumour spheroids, which give a hint about in vivo antitumor efficacy of SF-3 phytoconstituents. In conclusion, these results demonstrated that anticancer effects of SF-3 towards colon cancer are through modulation of multiple molecular pathways. | Muhammad Asif Armaghan Shafaei Aman Shah Abdul Majid Mohammed Oday Ezzat Saad S Dahham Mohamed B.Khadeer Ahamed Chern Ein Oon Amin Malik Shah Abdul Majid | 2017 | Chinese Journal of Natural Medicines2017，15，7： | 2 |
| 13 | Affecting Factors of Chronic Diarrhea in Children under 3 Years of Age显示文摘The major cause of sickness in today’s developing world is Persistent diarrhea.The aim of this study is to examine the factors of chronic diarrhea,and provide resistance to children under 3 years of age.Prospective analytical case control study is used for data collection and analysis.The study is carried out in the Department of Pediatrics,Lady Reading Hospital and medical teaching institution,Peshawar,during 2016-17.This study includes 50 cases of acute diarrhea and 50 cases of chronic diarrhea controls under5 for analysis.The overall ratio of chronic diarrhea that occurred in children below 3 years,girl to boy is 4:2.The seasonal change revealed that in summer rainy season we have found the greatest amount of incidence of chronic diarrhea.In young age the risk factors of chronic diarrhea has been observed as,poor nutritional status,lack of exclusive breast feeding,incomplete vaccination,irrational or overdose use of antibiotics during acute diarrhea,lack of sanitation facility at home and poor water supply.Thus,it has been suggested that the use of antibiotics is irrational and other medicines to cure diarrhea is discouraging.The awareness about the act of nurture and raise awareness about breast feeding and Expanded Programmed of Immunization(EPI)should be developed.For doctors,medical students and paramedical staff,Standard Diarrhea Case Management should be established.Sanitation facility and hygienic drinking water are also significant for the prevention of chronic diarrhea. | Muhammad Asif Kinza Amir Sana Amin XIE Hai-tang | 2017 | 世界最新医学信息文摘2017，17，A2： | 2 |
| 14 | Synthesis, chemical characterization, DNA binding, antioxidant, antibacterial, and antifungal activities of ferrocence incorporated selenoureas 显示文摘 | RAJA A H AMIN B MUHAMMAD N T | 2014 | J Biochem Mol Toxico12014，28，2： | 1 |
| 15 | Simulation of the thermal stress in mass concrete using a thermal stress measuring device显示文摘 | Muhammad Nasir Amin Jeong-Su Kim Yun Lee Jin-Keun Kim | 2008 | Cement and Concrete Research2008，，3： | 1 |
| 16 | Recent research progress in the synthesis Of polyphosphazene and their applications 显示文摘 | Amin Abid Muhammad Wang Li Wang Jianjun | 2009 | Des Monomers Polym2009，12，5： | 1 |
| 17 | A Study towards Proposing GPS - Based MobileAdvertisemem Service显示文摘 | Pantea Keikhosrokiani Norlia Mustaffa Muhammad Imran Sar- war Amin Kianpisheh Faten Damanhoori and Nasriah Zakaria | 2014 | :52 -5442014，，： | 1 |
| 18 | PCR Targeting of Antibiotic Resistant Bacteria in Public Drinking Water of Lahore Metropolitan,Pakistan显示文摘Objective To investigate the prevalence of kanamycin(kan) and ampicillin(amp) resistant bacteria in public drinking water.Methods Bacteria containing kan and amp resistant genes were amplified by PCR and further characterized by colony hybridization and transformation studies.The genus of kan and amp resistant bacteria was determined with standard methods.Results Among the 625 drinking water samples,400 contained kan and amp resistant bacteria and the percentage was 42.5% and 57.5%,respectively,which was further confirmed by the amplification of a 810 bp kan resistant gene and a 850 bp amp resistant gene.Of the 170 kan resistant bacteria,90 were Gram negative and 80 were Gram positive.Of the 230 amp resistant bacteria,160 were Gram negative while 70 were Gram positive.Salmonella,Shigella,Staphylococcus,Streptococcus,and E.coli were detected as 13%,11%,17%,30%,and 29%,respectively.Bacterial strain DH5α transformed with plasmids isolated from kan and amp resistant bacteria confirmed that the antibiotic resistant genes were mediated by plasmids.Conclusion Drinking water is contaminated with kan and amp resistant bacteria due to poor sanitary conditions. | ZAHOOR QADIR SAMRA MARIAM NASEEM SUMARIA JAVED KHAN NADIA DAR MUHAMMAD AMIN ATHAR | 2009 | Biomedical and Environmental Sciences2009，22，6： | 1 |
| 19 | Succinate-bonded pullulan: An efficient and reusable super-sorbent for cadmium-uptake from spiked high-hardness groundwater显示文摘Chemically modified pullulan was evaluated for its sorption efficiency and selectivity to remove cadmium(Cd) from spiked high-hardness groundwater(GW). Pullulan esterified with succinic anhydride using dimethylaminopyridine showed a fairly high degree of substitution value as confirmed by1 H NMR spectroscopy. Pullulan succinate(Pull-Suc) was converted into the sodium salt(Pull-Suc-Na). The effect of contact time(5–200 min) and p H(2–8) on Cd-uptake by the sorbent(Pull-Suc-Na) was investigated. The sorbent showed more than 90% Cd-removal in first 15 min from distilled water(DW) and GW solution,respectively. Comparison of Pull-Suc-Na with other polysaccharidal sorbents suggested its high efficiency(DW 476.2 mg/g and GW 454.5 mg/g) and selectivity for the removal of Cd by an ion exchange mechanism, which is further supported by the negative Gibbs free energy values calculated from Langmuir isotherms. A Langmuir isotherm kinetic model provided the best fit for the sorption of Cd using Pull-Suc-Na. The sorbent showed a negligible decrease in Cd-uptake over three regeneration cycles. The thermal stability testing of the sorbents indicated that Pull-Suc-Na(sorbent) is more stable than Pull-Suc. | Azhar Abbas Muhammad Ajaz Hussain Muhammad Amin Muhammad Sher Muhammad Nawaz Tahir Wolfgang Tremel | 2015 | Journal of Environmental Sciences2015，27，11： | 1 |
| 20 | Differential expression of specific cellular defense proteins in rat hypothalamus under simulated microgravity induced conditions: Comparative proteomics显示文摘 | Javed Iqbal Wang Li Murtaza Hasan Kefu Liu Umer Awan Yasmeen Saeed Yongqian Zhang Arif Muhammad Khan Amin Shah Hong Qing Yulin Deng | 2014 | Proteomics2014，，11： | 1 |
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