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| 1 | Vaccinations in immunosuppressive-dependent pediatric inflammatory bowel disease显示文摘AIM To determine the vaccination rates in pediatric immunosuppression-dependent inflammatory bowel disease(IBD) and review the safety and efficacy of vaccinations in this population.METHODS The electronic medical records from October 2009 to December 2015 of patients diagnosed with IBD at 10 years of age or younger and prescribed antitumor necrosis factor alpha(anti-TNF-α) therapy were reviewed for clinical history, medication history, vaccination history, and hepatitis B and varicella titers. Literature discussing vaccination response in IBD patients were identified through search of the MEDLINE database and reviewed using the key words 'inflammatory bowel disease', 'immunization', 'vaccination', 'pneumococcal', 'varicella', and 'hepatitis B'. Non-human and non-English language studies were excluded. Search results were reviewed by authors toselect articles that addressed safety and efficacy of immunizations in inflammatory bowel disease.RESULTS A total of 51 patients diagnosed with IBD prior to the age of 10 and receiving anti-TNF-α therapy were identified. Thirty-three percent of patients(17/51) had incomplete or no documentation of vaccinations. Sixteen case reports, cohort studies, cross-sectional studies, and randomized trials were determined through review of the literature to describe the safety and efficacy of hepatitis B, pneumococcal, and varicella immunizations in adult and pediatric patients with IBD. These studies showed that patients safely tolerated the vaccines without significant adverse effects. Importantly, IBD patients receiving immunosuppressive medications, particularly anti-TNF-α treatment, have decreased vaccine response compared to controls. However, the majority of patients are still able to achieve protective levels of specific antibodies. CONCLUSION Immunizations have been shown to be well-tolerated and protective immunity can be achieved in patients with IBD requiring immunosuppressive therapy. | Huyen-Tran Nguyen Phillip Minar Kimberly Jackson Patricia C Fulkerson | 2017 | World Journal of Gastroenterology2017，23，42： | 2 |
| 2 | Inflammation and Carotid Artery—Risk for Atherosclerosis Study (ICARAS)显示文摘 | Martin Schillinger Markus Exner Wolfgang Mlekusch Schila Sabeti Jasmin Amighi Robert Nikowitsch Ewald Timmel Bernhard Kickinger Christoph Minar Matthias Pones Wolfgang Lalouschek Helmut Rumpold Gerald Maurer Oswald Wagner Erich Minar | 2005 | Circulation2005，，17： | 2 |
| 3 | Sustained Benefit at 2 Years of Primary Femoropopliteal Stenting Compared With Balloon Angioplasty With Optional Stenting显示文摘 | Martin Schillinger Schila Sabeti Petra Dick Jasmin Amighi Wolfgang Mlekusch Oliver Schlager Christian Loewe Manfred Cejna Johannes Lammer Erich Minar | 2007 | Circulation2007，，： | 2 |
| 4 | D-dimer levels and risk of recurrent venous thromboembolism显示文摘 | Eichinger S Minar E Bialonczyk C | 2003 | JAMA2003，290，8： | 1 |
| 5 | The role of heme oxygenase-1 promoter polymorphisms in human disease 显示文摘 | EXNER M MINAR E WAGNER O | 2004 | Free Radic Bioc Meal2004，37，8： | 1 |
| 6 | Heme oxygenase-1 genotype and restenosis after balloon angioplasty:a novel vascular protective factor显示文摘 | Schillinger M Exner M Minar E | 2004 | J Am Coll Cardiol2004，43，6： | 1 |
| 7 | Chemotherapy of advanced non-small cell lung cancer显示文摘 | Pirker R Minar W | 2010 | Front Radiat Ther Oncol2010，42，： | 1 |
| 8 | Thromboxane A2 and prostacyclin generation in the microvasculature of patients with atherosclerosis-effect of low-dose aspirin显示文摘 | MINAR E BRENNER B | 1989 | Thromb Haemost1989，61，3： | 1 |
| 9 | EndovasculaI stent implantation for treatment of peripheral artery disease显示文摘 | Schillinger M Minar E | 2007 | Eur J Clin Invest2007，37，3： | 1 |
| 10 | Exploration of the early auditory effects of hyperlipoproteinemia and diabetes mellitus using oto aeoustic emissions显示文摘 | ErdemT Ozturan O Minar MC | 2003 | Eur Arch Otorbinolaryngol2003，260，： | 1 |
| 11 | Heme oxygenase-1 genotype and restenosis after balloon angioplasty: a novel vascular protective factor显示文摘 | Schillinger M Exner M Minar E | 2004 | J Am Coil Cardiol2004，43，6： | 1 |
| 12 | Endovascular brachytherapy for prophylaxis of restenosis after femoropopliteal angioplasty:results of a prospective randomized study显示文摘 | Minar E Pokrajac B Maca T | 2000 | Circulation2000，102，22： | 1 |
| 13 | The Risk of Recurrent Venous Thmmbolism in Men and Women 显示文摘 | Kyrle PA Minar E Bialonciyk C | 2004 | The Nen England Journal of Medicine2004，350，： | 1 |
| 14 | D-dimer levels and risk of re- current venous thromboembolism 显示文摘 | Eichinger S Minar E Bialonczyk C | 2003 | JAMA2003，290，8： | 1 |
| 15 | Access site management after peripheral percutaneous transluminal procedures:Neptune pad compared with conventional manual compression显示文摘 | Mlekusch W Minar E Dick P | | 0，，03： | 1 |
| 16 | The role of heme oxygenase-1 promoter polymorphisms in human disease显示文摘 | EXNER M MINAR E WAGNER O | 2004 | Free Radic Biol Med2004，37，： | 1 |
| 17 | Association of a Functional Polymorphism in the Clopidogrel Target Receptor Gene, P2Y12, and the Risk for Ischemic Cerebrovascular Events in Patients With Peripheral Artery Disease显示文摘 | Sophie Ziegler Martin Schillinger Marion Funk Katharina Felber Markus Exner Wolfgang Mlekusch Schila Sabeti Jasmin Amighi Erich Minar Martin Brunner Markus Müller Christine Mannhalter | 2005 | Stroke2005，，7： | 1 |
| 18 | The role of heme oxygenase-1 promoter polymorphisms in human disease显示文摘 | Exner M Minar E Wagner O | 2004 | Free Radic Biol Med2004，37，8： | 1 |
| 19 | Chemotherapy of advanced non-small celllung cancer显示文摘 | Pirker R Minar W | 2010 | Front Radiat Ther Oncol2010，42，2： | 1 |
| 20 | Haem oxygenase-1 genotype and cardiovascular adverse events in patients with peripheral artery disease显示文摘 | Dick P Schillinger M Minar E | 2005 | Eur J Clin Invest2005，35，12： | 1 |
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