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| 1 | Long-term outcome and prognostic factors of patients with hilar cholangiocarcinoma显示文摘AIM: To evaluate the long-term outcome and prognostic factors of patients with hilar cholangiocarinoma. METHODS: Ninety-six consecutive patients underwent treatment for malignant hilar bile duct tumors during 1995–2005. Of the 96 patients, 20 were initially treated with surgery (n = 2 R0 / n = 18 R1). In non-operated patients, data analysis was performed retrospectively. RESULTS: Among the 96 patients, 76 were treated with endoscopic transpapillary (ERC, n = 45) and/or percutaneous transhepatic biliary drainage (PTBD, n = 31). The mean survival time of these 76 patients undergoing palliative endoscopic and/or percutaneous drainage was 359 ± 296 d. The mean survival time of patients with initial bilirubin levels > 10 mg/dL was significantly lower (P < 0.001) than patients with bilirubin levels < 10 mg/dL. The mean survival time of patients with Bismuth stage Ⅱ (n = 8), Ⅲ (n = 28) and Ⅳ (n = 40) was 496 ± 300 d, 441 ± 385 d and 274 ± 218 d, respectively. Thus, patients with advanced Bismuth stage showed a reduced mean survival time, but the difference was not significant. The type of biliary drainage had no significant beneficial effect on the mean survival time (ERC vs PTBD, P = 0.806). CONCLUSION: Initial bilirubin level is a significant prognostic factor for survival of patients. In contrast, age, tumor stage according to the Bismuth-Corlette classification, and types of intervention are not significant prognostic parameters for survival. Palliative treatment with endoscopic or percutaneous biliary drainage is still suboptimal, new diagnostic and therapeutic tools need to be evaluated. | Andreas Weber Sonja Landrock Jochen Schneider Manfred Stangl Bruno Neu Peter Born Meinhard Classen Thomas Rsch Roland M Schmid Christian Prinz | 2007 | World Journal of Gastroenterology2007，13，9： | 23 |
| 2 | Eradication of H pylori infection in a rural population: One-day quadruple therapy versus 7-day triple therapy显示文摘瞄准:比较有标准 7-d 的四倍的治疗增加两倍的一天为在中国的一张农村人口的 H pylori 根除的治疗。方法:396 个病人与的一个总数(13 ) pylori 被分配进二的为 H 阳性的 C 脲呼吸测试组织:239 个病人收到了一天四倍的治疗(amoxicillin 2000 mg qid;灭滴灵 500 mg qid;枸橼酸铋 900 mg qid 和 lansoprazole 60 mg 从前每日) 并且 157 个病人收到了 7-d 标准三元组治疗(amoxicillin 1000 mg 出价;clarithromycin 500 mg 出价和 lansoprazole 30 mg 出价) 。所有病人经历了一(13 ) 六个星期估计 H pylori 感染的根除的 C-UBT 术后疗法。结果:229 个病人完成了一天治疗(95.8%) , 148 个病人完成了 7-d 治疗(94.2%) 。一天治疗根除了在 64 个病人(27.95%) 的 H pylori 感染。相反, 103 个病人(69.59%) 是在 7-d 治疗以后否定的 H pylori (P <
0.01 ) 。结论:这个预研项目建议与 7-d 标准治疗相比没有在 H pylori 感染的治疗的一天治疗的有益的效果。 | Lian Zhang Lin Shen Jun-Ling Ma Kai-Feng Pan Wei-Dong Liu Jie Li Shu-Dong Xiao San-Ren Lin Meinhard Classen Wei-Cheng You | 2006 | World Journal of Gastroenterology2006，12，24： | 6 |
| 3 | ERCP or EUS for tissue diagnosis of biliary strictures? a prospective comparative study显示文摘 | Thomas R?sch Kim Hofrichter Eckart Frimberger Alexander Meining Peter Born Norbert Weigert Hans-Dieter Allescher Meinhard Classen Marius Barbur Ulrich Schenck Martin Werner | 2004 | Gastrointestinal Endoscopy2004，，3： | 1 |
| 4 | A prospective comparison of the diagnostic accuracy of ERCP, MRCP, CT, and EUS in biliary strictures显示文摘 | Thomas R?sch Alexander Meining Silke Frühmorgen Christian Zillinger Volker Schusdziarra Karin Hellerhoff Meinhard Classen Hermann Helmberger | 2002 | Gastrointestinal Endoscopy2002，，7： | 1 |
| 5 | Modern imaging methods versus clinical assessment in the evaluation of hospital in-patients with suspected pancreatic disease显示文摘 | Thomas R?sch Volker Schusdziarra Peter Born Werner Bautz Markus Baumgartner Kurt Ulm Reinhard Lorenz Hans-Dieter Allescher Paul Gerhardt J?rg-Rüdiger Siewert Meinhard Classen | 2000 | The American Journal of Gastroenterology2000，，9： | 1 |
| 6 | Randomized study of intracorporeal laser lithotripsy versus extracorporeal shock-wave lithotripsy for difficult bile duct stones显示文摘 | Horst Neuhaus Christian Zillinger Peter Born Roland Ott Hans Allescher Thomas R?sch Meinhard Classen | 1998 | Gastrointestinal Endoscopy1998，，5： | 1 |
| 7 | Modern imaging methods versus clinical assessment in the evaluation of hospital in-patients with suspected pancreatic disease显示文摘 | Thomas R?sch Volker Schusdziarra Peter Born Werner Bautz Markus Baumgartner Kurt Ulm Reinhard Lorenz Hans-Dieter Allescher Paul Gerhardt J?rg-Rüdiger Siewert Meinhard Classen | 2000 | The American Journal of Gastroenterology2000，，9： | 1 |
| 8 | Modern imaging methods versus clinical assessment in the evaluation of hospital in-patients with suspected pancreatic disease显示文摘 | Thomas R?sch Volker Schusdziarra Peter Born Werner Bautz Markus Baumgartner Kurt Ulm Reinhard Lorenz Hans-Dieter Allescher Paul Gerhardt J?rg-Rüdiger Siewert Meinhard Classen | 2000 | The American Journal of Gastroenterology2000，，9： | 1 |
| 9 | Superior mesenteric artery syndrome: diagnosis and treatment from the gastroenterologist’s view显示文摘 | Florian Lippl Christian Hannig Wolfgang Wei? Hans-Dieter Allescher Meinhard Classen Manfred Kurjak | 2002 | Journal of Gastroenterology2002，，8： | 1 |
| 10 | ERCP or EUS for tissue diagnosis of biliary strictures? a prospective comparative study显示文摘 | Thomas R?sch Kim Hofrichter Eckart Frimberger Alexander Meining Peter Born Norbert Weigert Hans-Dieter Allescher Meinhard Classen Marius Barbur Ulrich Schenck Martin Werner | 2004 | Gastrointestinal Endoscopy2004，，3： | 1 |
| 11 | Treatment of esophagorespiratory fistulas with silicone-coated self-expanding metal stents显示文摘 | Norbert Weigert Horst Neuhaus Thomas R?sch Werner Hoffmann Hans J. Dittler Meinhard Classen | 1995 | Gastrointestinal Endoscopy1995，，5： | 1 |
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