|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Long-term outcome and prognostic factors of patients with hilar cholangiocarcinoma显示文摘AIM: To evaluate the long-term outcome and prognostic factors of patients with hilar cholangiocarinoma. METHODS: Ninety-six consecutive patients underwent treatment for malignant hilar bile duct tumors during 1995–2005. Of the 96 patients, 20 were initially treated with surgery (n = 2 R0 / n = 18 R1). In non-operated patients, data analysis was performed retrospectively. RESULTS: Among the 96 patients, 76 were treated with endoscopic transpapillary (ERC, n = 45) and/or percutaneous transhepatic biliary drainage (PTBD, n = 31). The mean survival time of these 76 patients undergoing palliative endoscopic and/or percutaneous drainage was 359 ± 296 d. The mean survival time of patients with initial bilirubin levels > 10 mg/dL was significantly lower (P < 0.001) than patients with bilirubin levels < 10 mg/dL. The mean survival time of patients with Bismuth stage Ⅱ (n = 8), Ⅲ (n = 28) and Ⅳ (n = 40) was 496 ± 300 d, 441 ± 385 d and 274 ± 218 d, respectively. Thus, patients with advanced Bismuth stage showed a reduced mean survival time, but the difference was not significant. The type of biliary drainage had no significant beneficial effect on the mean survival time (ERC vs PTBD, P = 0.806). CONCLUSION: Initial bilirubin level is a significant prognostic factor for survival of patients. In contrast, age, tumor stage according to the Bismuth-Corlette classification, and types of intervention are not significant prognostic parameters for survival. Palliative treatment with endoscopic or percutaneous biliary drainage is still suboptimal, new diagnostic and therapeutic tools need to be evaluated. | Andreas Weber Sonja Landrock Jochen Schneider Manfred Stangl Bruno Neu Peter Born Meinhard Classen Thomas Rsch Roland M Schmid Christian Prinz | 2007 | World Journal of Gastroenterology2007，13，9： | 23 |
| 2 | Eradication of H pylori infection in a rural population: One-day quadruple therapy versus 7-day triple therapy显示文摘瞄准:比较有标准 7-d 的四倍的治疗增加两倍的一天为在中国的一张农村人口的 H pylori 根除的治疗。方法:396 个病人与的一个总数(13 ) pylori 被分配进二的为 H 阳性的 C 脲呼吸测试组织:239 个病人收到了一天四倍的治疗(amoxicillin 2000 mg qid;灭滴灵 500 mg qid;枸橼酸铋 900 mg qid 和 lansoprazole 60 mg 从前每日) 并且 157 个病人收到了 7-d 标准三元组治疗(amoxicillin 1000 mg 出价;clarithromycin 500 mg 出价和 lansoprazole 30 mg 出价) 。所有病人经历了一(13 ) 六个星期估计 H pylori 感染的根除的 C-UBT 术后疗法。结果:229 个病人完成了一天治疗(95.8%) , 148 个病人完成了 7-d 治疗(94.2%) 。一天治疗根除了在 64 个病人(27.95%) 的 H pylori 感染。相反, 103 个病人(69.59%) 是在 7-d 治疗以后否定的 H pylori (P <
0.01 ) 。结论:这个预研项目建议与 7-d 标准治疗相比没有在 H pylori 感染的治疗的一天治疗的有益的效果。 | Lian Zhang Lin Shen Jun-Ling Ma Kai-Feng Pan Wei-Dong Liu Jie Li Shu-Dong Xiao San-Ren Lin Meinhard Classen Wei-Cheng You | 2006 | World Journal of Gastroenterology2006，12，24： | 6 |
| 3 | 【特刊综述】骨骼两性异形中的雄激素和雌激素显示文摘骨骼是表达雄激素、雌激素受体以及类固醇代谢酶的一种内分泌组织。循环性激素的生物活性通过六种性激素结合球蛋白以及在骨组织中的局部转变来进行调节,例如,睾酮通过芳香酶转变成雌二醇,或通过5α还原酶转变成双氢睾酮。由于高分辨外周CT应用的增多,我们对造成骨骼强度性别差异的结构基础的认识在近几年有很大进步。这些对微小结构的观察是理解性激素对男性峰值骨量及对骨皮质和骨小梁之间转变的影响的基础。最近的研究利用Cre/LoxP技术使我们在整体基因敲除小鼠上机械的认识精确到性激素及其在成骨细胞、破骨细胞、骨细胞以及其它造成男性骨质疏松的细胞上的核受体的直接作用。同时,这些研究加强了这样的观点:雄激素和雌激素的缺乏通过与例如胰岛素样生长因子1、炎症、氧化应激、骨骼代谢的中枢神经系统控制、机械负荷的适应等的交互作用发挥直接和多种效应。这篇综述将总结性激素在男性骨骼自身平衡作用这个领域有关方面最近的进展。 | Michael Laurent Leen Antonio Mieke Sinnesael Vanessa Dubois Evelien Gielen Frank Classens Dirk Vanderschueren | 2014 | Asian Journal of Andrology2014，16，2： | 4 |
| 4 | A New Method for the Endoscopic Determination of Gastrointestinal Ulcer Area显示文摘 | H. Dancygier D. Wurbs M. Classen | 1981 | Endoscopy1981，，05： | 2 |
| 5 | Community-level physiological profiles of bacteria and fungi: plate type and incubation temperature influences on contrasting soils显示文摘 | Aimée T Classen Sarah I Boyle Kristin E Haskins Steven T Overby Stephen C Hart | | FEMS Microbiology Ecology0，，： | 2 |
| 6 | A Study of electrocardiographic patterns in a population of commercial broiler chickens 显示文摘 | Olkowski A A Classen H L Riddle C | 1997 | Veterinary Research Communications1997，21，： | 2 |
| 7 | Nutrient removal from swine lagoon effluent by duckweed显示文摘 | Cheng J Classen J | 2000 | Transactions of the American Society of Agricultural Engineering2000，42，2： | 1 |
| 8 | Daily meatal care for prevention of catheter-associated bacteriuria:results using frequent applications of polyantibiotic cream显示文摘 | Classen D C Larsen R A Burke J P | 1991 | Infect Control Hosp Epidemiol1991，12，3： | 1 |
| 9 | Phosphorus efficiency of plantsⅠ: external and internal P requirement and uptake efficiency of different plant species显示文摘 | Foehes D Classen N Jungk A | 1998 | Plant & Soil1998，110，： | 1 |
| 10 | Function of CD40 and its ligand,gp39 (CD40L) 显示文摘 | Laman JD Classen E Noelle RJ | 1996 | Crit Rev Inmmunol1996，16，1： | 1 |
| 11 | Nutrient removal from swine lagoon water by duckweed显示文摘 | Bergmann B A Cheng J Classen J J | 2000 | Transaction of the ASAE2000，43，2： | 1 |
| 12 | Modulation of antiviral immune responses by exogenous cytokines:effect of tumor necrosis factor-α, interleukin-1α, interleukin-2 and interferon-γ on immunogeniclty of an inactivated rabies vaccin显示文摘 | Schijins V E C J Classen I J T H Vermeulen A A | 1994 | Gen Virol1994，75，： | 1 |
| 13 | In vitro techniques for the assessment of neurotoxicity 显示文摘 | Harry GJ Billingsley M Bruinink A Campbell IL Classen W Dorman DC | 1998 | Environ Health Perspect1998，106，1： | 1 |
| 14 | The timing of prophylactic administration of antibiotics and the risk of surgicalwound infection 显示文摘 | Classen DC Evans RS Pestotnik SL | 1992 | New Engl J Med1992，326，5： | 1 |
| 15 | Depression of motor cortex excitability by low-frequency transcranial magnetic stimulation显示文摘 | Chen R Classen J Gerloff C | 1997 | Neurology1997，48，： | 1 |
| 16 | Organic phosphorous compounds as a phosphorous source for higher plants through the activity of phosphatase produced by plant roots microorganisms显示文摘 | Tarafdar JC Classen N | 1988 | Biol Fertil Soils1988，5，： | 1 |
| 17 | Endoskpische sphincterotomie der papilla Vateri und stainextrakion aus ductus choledochus 显示文摘 | Classen M Demling L | 1974 | Dtsch Med Wochenschr1974，99，： | 1 |
| 18 | In vitro hydrolysis of phytate in canola meal with purified and crude sources of phytase显示文摘 | NEWKIRK R W CLASSEN H L | 1998 | Journal of Animal and Feed Sciences1998，72，： | 1 |
| 19 | Endoscopic ultrasonographyin the evaluation of colon and rectal disease 显示文摘 | Rosch T Lorenz R Classen M | 1990 | Gastrointestinal Endoscopy1990，36，2： | 1 |
| 20 | Nutritional evaluation of low glucosinolate mustard meals (Brassica juncea) in broiler diets 显示文摘 | Newkirk R W Classen H L Tyler R T | 1997 | Poult Sci1997，76，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员