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| 1 | 血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂的使用与2019冠状病毒疾病检测阳性之间的关系显示文摘血管紧张素转换酶抑制剂(angiotensin-converting enzyme inhibitor,ACEI)和血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)在2019新型冠状病毒疾病(coronavirus disease 2019,COVID-19)全球大流行背景下的作用备受争议。此类药物是治疗一些慢性病的必须药物,有建议停止使用这些药物. | Mehta N KalraA Nowacki AS Anjewierden S Han Z Bhat p Rubio AEC Jacob M Procop GW Harrington S Milinovich A Svensson LG Jehi L Young JB Chung MK 周卫(译) 叶鹏(校) | 2020 | 中华高血压杂志2020，28，5： | 9 |
| 2 | RTOG 0211:a phase 1/2 study of radiation therapy with concurrent gefitinib for newly diagnosed glioblastoma patients显示文摘PURPOSE: To determine the safety and efficacy of gefitinib,an epidermal growth factor receptor(EGFR) tyrosine kinase inhibitor,in combination with radiation for newly diagnosed glioblastoma(GBM) patients.METHODS AND MATERIALS: Between March 21,2002,and May 3,2004,Radiation Therapy Oncology Group(RTOG) 0211 enrolled 31 and 147GBM patients in the phase 1 and 2 arms,respectively.Treatment consisted of daily oral gefinitnib started at the time of conventional cranial radiation therapy(RT) and continued post RT for 18 months or until progression.Tissue microarrays from 68 cases were analyzed for EGFR expression.RESULTS: The maximum tolerated dose(MTD) of gefitinib was determined to be 500 mg in patients on non-enzyme-inducing anticonvulsant drugs(non-EIAEDs).All patients in the phase 2 component were treated at a gefitinib dose of 500 mg;patients receiving EIADSs could be escalated to 750 mg.The most common side effects of gefitinib in combination with radiation were dermatologic and gastrointestinal.Median survival was 11.5 months for patients treated per protocol.There was no overall survival benefit for patients treated with gefitinib + RT when compared with a historical cohort of patients treated with RT alone,matched by RTOG recursive partitioning analysis(RPA) class distribution.Younger age was significantly associated with better outcome.Per protocol stratification,EGFR expression was not found to be of prognostic value for gefitinib + RT-treated patients.CONCLUSIONS: The addition of gefitinib to RT is well tolerated.Median survival of RTOG 0211 patients treated with RT with concurrent and adjuvant gefitinib was similar to that in a historical control cohort treated with radiation alone. | Chakravarti A Wang M Robins HI Lautenschlaeger T Curran WJ Brachman DG Schultz CJ Choucair A Dolled-Filhart M Christiansen J Gustavson M Molinaro A Mischel P Dicker AP Bredel M Mehta M | 2013 | 中国神经肿瘤杂志2013，11，1： | 8 |
| 3 | Excitotoxicity: bridge tovarious triggers in neurodegenerative disorders 显示文摘 | Mehta A Prabhakar M Kumar P | 2013 | Eur JPharmacol2013，698，13： | 1 |
| 4 | Soluble monomeric P - selectin containing only the lectin and epidermal growth factor domains binds to P - selectin glycoprotein ligand - 1 on leukocytes 显示文摘 | MEHTA P PATEL K D LAUE T M | 1997 | Blood1997，90，6： | 1 |
| 5 | The blood coagulation mechanism in multiple myeloma显示文摘 | Zangari M Saghafifar F Mehta P | 2003 | Semin Thromb Hemost2003，29，3： | 1 |
| 6 | 查看详情显示文摘 | Haynam C A Wegner P J Auerbach J M Bowers M W Dixit S N Erbert G V Heestand G M Henesian M A Hermann M R Jancaitis K S Manes K R Marshall C D Mehta N C Menapace J Moses E Murray J R Nostrand M C Orth C D Patterson R SacksR A Shaw M J Spaeth M Sutton S B W | | 0，，： | 1 |
| 7 | Impact of transtradial and transfemoral coronary interventions on bleeding and net adverse clinical events in acute coronary syndromes显示文摘 | Hamon M Mehta S Steg P G | 2011 | Eurointervention2011，7，1： | 1 |
| 8 | Active power filter:a review显示文摘 | EI-HABROUK M DARWISH M K MEHTA P | 2000 | IEE Proceeding-Electric Power Applications2000，147，5： | 1 |
| 9 | Effect of compressed CO2 on crystallization and melting behavior of isotactic polyproplene显示文摘 | Varma-Nair M Handa P Y Mehta A K | 2003 | ThermochimicaActa2003，396，： | 1 |
| 10 | Ferreting out tunneling: An application to Indian business groups显示文摘 | Bertrand M Mehta P Mullainathan S | 2002 | The Quarterly Journal of Economics2002，117，1： | 1 |
| 11 | Field measurements of pressures on the Texas Tech building 显示文摘 | LEVITAN M L MEHTA K C VANN W P HOLMES J D | 1991 | Journal of Wind Engineering and Industrial Aerodynamics1991，38，23： | 1 |
| 12 | Behavior problems in nephrotie syndrome 显示文摘 | MEHTA M BAGGA A PANDE P | 1995 | Indian Pediatr1995，32，12： | 1 |
| 13 | , mULLAINATHAN,'Ferreting Out Tunneling:An Application ToIndian Business Groups'显示文摘 | M P mEHTA S | 2002 | the Quarterly Journal of Economics2002，117，： | 1 |
| 14 | Ferreting out Tunneling: An Application to Indi- an Business Groups 显示文摘 | BERTRAND M MEHTA P MULLAINATHAN S | 2002 | Quarterly Journal of Eco- nomics2002，117，1： | 1 |
| 15 | Behavior problems in nephrotic syndrome 显示文摘 | Mehta M Bagga A Pande P | 1995 | Indian Pediatr1995，32，12： | 1 |
| 16 | Early diagnosis of mycotic keratitis: predictive value of potassium hydroxide preparation 显示文摘 | Sharma S Silverberg M Mehta P | 1998 | Indiam J Ophthalmol1998，46，1： | 1 |
| 17 | Doselimiting toxicity after hypofractionated dose-escalated radiotherapy in non-small-cell lung cancer 显示文摘 | CANNON D M MEHTA M P ADKISON J B | 2013 | J Clin Oncol2013，31，34： | 1 |
| 18 | Facilitation of rapid endotracheal intubations with divided doses of nondepolarizing neuromuscular blocking drugs 显示文摘 | MEHTA M P CHOI W W GERGIS S D | 1985 | Anesthesiology1985，62，4： | 1 |
| 19 | Ferreting Out Tunneling: An Application to Indian Business Groups显示文摘 | Bertrand M Mehta P Mullainathan S | 2002 | The Quarterly Journal of Economics2002，117，1： | 1 |
| 20 | Role of isocitrate dehydrogenase in glioma 显示文摘 | Alexander B M Mehta M P | 2011 | Expert Rev Neurother2011，11，10： | 1 |
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