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| 1 | Defensin expression in chronic pouchitis in patients with ulcerative colitis or familial adenomatous polyposis coli显示文摘瞄准:当在在为家庭腺瘤息肉病关口 i (FAP ) 的 proctocolectomy 以后的病人是稀罕的时, Pouchitis 在小袋外科以后在开始的 10 年期间与 ulcerative 在多达 50% 病人在 ileoanal 小袋发展症候群。Defensins 是天生的免疫系统的主要部件并且在胃肠的微生物引起的动态平衡起一个重要作用。小袋 defensin 和 cytokine 表示与小袋发炎的状态被相关在 pouchitis 学习他们的角色。方法:有 ulcerative 和 FAP 症候群的病人在外科以后与小袋被成层进组,小袋没有或与 pouchitis。从从健康的肠或从有 ulcerative 的病人的正常终端回肠的终端回肠的活体检视用作控制。从小袋和控制的 mRNA 为 defensin 和 cytokine 表示被分析。结果:defensins 的表示在外科以后立即在所有小袋被增加,与控制的回肠相比。开始,在 ulcerative 的小袋比 FAP 小袋揭示了更高的 defensin 表示。Defensin 表示在两个耐心的组衰退了并且与 ulcerative 在病人在 pouchitis 稍微再增加了。没有 pouchitis 的 FAP 小袋有 beta-defensin hBD-1 的强壮的表示,当所有另外的 defensins 在底层留下了时。在 ulcerative 小袋的 Cytokine 表示高,当 FAP 小袋仅仅在外科以后显示出中等提高的 cytokines 时。结论:pouchitis 的开发除了 cytokines 的高表示在 ulcerative 与减少的 defensin 表示相关。在 FAP 小袋的 pouchitis 的低发生与低 cytokine 层次联合与 hBD-1 beta-defensin 的增加的表示相关。 | Karlheinz Kiehne Gabriele Brunke Franziska Wegner Tomas Banasiewicz Ulrich R F lsch Karl-Heinz Herzig | 2006 | World Journal of Gastroenterology2006，12，7： | 8 |
| 2 | 温带气候条件下夏季温度和温湿度指数对母猪繁殖性能的影响显示文摘热应激在温带气候条件下如何影响母猪的繁殖性能一直是未知的。因此,我们于2009年至2011年对温度及温湿度指数在夏季对母猪繁殖性能的影响进行了研究。在德国的22个猪场内,人工授精的22 264头母猪最终有21 610头母猪分娩,并记录详细的繁殖参数。气象数据来自养殖场最近的气象站。每年的5月到9月温度会影响舍内温度,研究此时间段温度及温湿度指数对母猪不同繁殖性能阶段的影响。配种前5 d和配种后14 d的高温和高温湿度指数(TemperatureHumidity Index,THI)引起窝产仔数减少0.01~0.03头(P<0.05)。分娩前,随着温度变异越大,活仔数减少而僵猪数增加(P<0.001)。分娩当天的温度和THI升高时,断奶仔猪的数量减少(P<0.05),但断奶前仔猪死亡率不受影响(P>0.05)。总之,即便在温带条件下,气候的变化仍然会对母猪的繁殖性能产生不利影响。因此,活仔数是反映热应激最为敏感的参数。由于气候变化和可能即将到来的热浪对母猪繁殖性能的影响,缓和热应激对母猪的影响必不可少。 | Kerstin Wegner christian Lambertz 曾浩廉(译) 周琳(译) 陈静波(译) 潘雪男(审) 何闪(制图表) | 2017 | 国外畜牧学(猪与禽)2017，0，5： | 2 |
| 3 | From headtotoes:the multiple facets of Sox proteins显示文摘 | wegner M | 1999 | Nucleic Acids Res1999，27，： | 2 |
| 4 | Rationally designed synthesis of bright AgInS2/ZnS quantum dots with emission control显示文摘In the blossoming field of Cd-free semiconductor quantum dots(QDs),ternary Ⅰ-Ⅲ-VI QDs have received increasing attention due to the ease of the environmentally friendly synthesis of high-quality materials in water,their high photoluminescence(PL)quantum yields(QYs)in the red and near infrared(NIR)region,and their inherently low toxicity.Moreover,their oxygen-insensitive long PL lifetimes of up to several hundreds of nanoseconds close a gap for applications exploiting the compound-specific parameter PL lifetime.To overcome the lack of reproducible synthetic methodologies and to enable a design-based control of their PL properties,we assessed and modelled the synthesis of high-quality MPA-capped AglnS2/ZnS(AlS/ZnS)QDs.Systematically refined parameters included reaction time,temperature,Ag:In ratio,S:In ratio,Zn:In ratio,MPA:ln ratio,and pH using a design-of-experiment approach.Guidance for the optimization was provided by mathematical models developed for the application-relevant PL parameters,maximum PL wavelength,QY,and PL lifetime as well as the elemental composition in terms of Ag:ln:Zn ratio.With these experimental data-based models,MPA:ln and Ag:ln ratios and pH values were identified as the most important synthesis parameters for PL control and an insight into the connection of these parameters could be gained.Subsequently,the experimental conditions to synthetize QDs with tunable emission and high QY were predicted.The excellent agreement between the predicted and experimentally found PL features confirmed the reliability of our methodology for the rational design of high quality AlS/ZnS QDs with defined PL features.This approach can be straightforwardly extended to other ternary and quaternary QDs and to doped QDs. | Jose X.Soares K.David Wegner David S.M.Ribeiro Armindo Melo Ines Hausler Joao L.M.Santos Ute Resch-Genger | 2020 | Nano Research2020，13，9： | 2 |
| 5 | A Matter of Identity: Transcriptional Control in Oligodendrocytes显示文摘 | Michael Wegner | 2008 | Journal of Molecular Neuroscience2008，，1： | 2 |
| 6 | 巴西的电气石和海蓝宝石矿床显示文摘 | César-Mendes,J. Jordt-Evange-Lista,H. Wegner,R. 赵琼 徐汀 杨梅珍 | 2001 | 宝石和宝石学杂志2001，3，2： | 2 |
| 7 | Macrophages in human visceral adipose tissue: ineressed accumulation in obesity and a source of resistin and visfatin显示文摘 | Curat CA Wegner V Sengends C | 2006 | Diabetologia2006，49，4： | 1 |
| 8 | Why interaction is more powerful than algorithms显示文摘 | Wegner P | 1997 | Communications of the ACM1997，40，5： | 1 |
| 9 | Oocyte activation as a bioassay for functional viability of oocytes after vitrification显示文摘 | Villines P M Gentry W L Wegner C C | 2005 | Fertil Steril2005，84，1： | 1 |
| 10 | SoxE function in vertebrate nervous system development显示文摘 | Stolt CC Wegner M | 2010 | Int J Biochem Cell Biol2010，42，3： | 1 |
| 11 | Macrophages in human visceral adiposetissue:Macrophages in human visceraladipose tissue:increased accumulationg in obesity and asource of resistin and visfatin显示文摘 | Curat CA Wegner V Sengenes C | 2006 | Diabetologia2006，49，4： | 1 |
| 12 | Astaxanthin lowem plasma TAG concentrations and increases hepatic antioxidant gene expression in diet-induced obesity mice 显示文摘 | YANG Y Pham TX Wegner CJ | 2014 | Br J Nutr2014，112，11： | 1 |
| 13 | Transcriptional regulation of the rat vascular endothelial growth factor gene by hypoxia 显示文摘 | Levy AP Levy NS Wegner S | 1995 | Biol Chem1995，270，13： | 1 |
| 14 | On under standing types, data abstraction, and polymorphism 显示文摘 | GARDELLI L WEGNER P | 1985 | Computer Survey1985，17，4： | 1 |
| 15 | Population effects of landscape model manipulation on two behaviourally different woodland small mammals显示文摘 | Henein K Wegner J Merriam G | 1998 | Oikos1998，81，： | 1 |
| 16 | Economic evaluation and survial analysis of immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy 显示文摘 | Hessel FP Wegner C Muller J | 2004 | Eur J Health Econom2004，5，1： | 1 |
| 17 | Activation of AP-1 and nuclear factor-kappaB transcription factors is involved in hydrogen peroxide-induced apoptotic cell death of oligodendrocytes显示文摘 | Vollgraf U Wegner M Richter-Landsberg C | 1999 | J Neurochem1999，73，6： | 1 |
| 18 | Long-term resin bond strength to zirconiacermic显示文摘 | Wegner SM kern M | 2000 | Adhes Dent2000，2，2： | 1 |
| 19 | Macrophages in human visceral adipose tissue : increase accumulation in obesity and a source of resistin and visfatin 显示文摘 | Curat CA Wegner V Sengenes C | 2006 | Diabetologia2006，49，4： | 1 |
| 20 | Subsynchronous resonance performance tests of the Slatt thyristor-controlled se- ries capacitor显示文摘 | Piwko R J Wegner C A Kinney S J | 1996 | IEEE Transactions on Power Delivery1996，11，2： | 1 |
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