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| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 2 | Interferon-γ: Promising therapeutic target in atherosclerosis显示文摘Atherosclerosis is a chronic inflammatory disorder of the vasculature and is the primary cause of cardiovascular disease(CVD). CVD is currently the world's leading cause of death and the numbers are predicted to rise further because of a global increase in risk factors such as diabetes and obesity. Current therapies such as statins have had a major impact in reducing mortality from CVD. However, there is a marked residual CVD risk in patients on statin therapy. It is therefore important to understand the molecular basis of this disease in detail and to develop alternative novel therapeutics. Interferon-γ(IFN-γ) is a pro-inflammatory cytokine that is often regarded as a master regulator of atherosclerosis development. IFN-γ is able to influence several key steps during atherosclerosis development, including pro-inflammatory gene expression, the recruitment of monocytes from the blood to the activated arterial endothelium and plaque stability. This central role of IFN-γ makes it a promising therapeutic target. The purpose of this editorial is to describe the key role IFN-γ plays during atherosclerosis development, as well as discuss potential strategies to target it therapeutically. | Joe WE Moss Dipak P Ramji | 2015 | World Journal of Experimental Medicine2015，5，3： | 7 |
| 3 | 诺西那生治疗脊髓性肌萎缩显示文摘目的观察诺西那生(Nusinersen)治疗脊髓性肌萎缩(SMA)患者的疗效和不良反应。方法回顾性分析2017年9月至2018年3月以色列施耐德儿童医学中心神经内科就诊的12例SMA患儿的临床资料。所有患儿均经基因检测证实为运动神经元存活基因(SMN)1纯合子7号外显子缺失,无SMN1杂合子突变。应用诺西那生12mg腰椎穿刺鞘内注射治疗,前4次鞘内给药为负荷剂量12mg,分别于1、15、30、60d给药,以后每4个月给予1次维持剂量12mg。于181d运用费城儿童医院神经肌肉障碍婴儿测试量表(CHOP-INTEND)和Hammersmith运动功能评分量表(HFMSE)量表评价患儿运动功能改善情况。结果治疗181d评价,早发型(SMA-Ⅰ)4例中2例CHOP-INTEND评分提高3分和5分,另2例肌张力有明显改善;晚发型(SMA-Ⅱ/SMA-Ⅲ/SMA-Ⅳ)8例HFMSE评分均有不同程度改善,最低提高3.1分,最高提高5.2分,平均提高4.1分。不良反应少且轻微。结论诺西那生治疗SMA的疗效肯定,安全性较好。 | 陈峥 Yoram Nevo Tanya Moss | 2019 | 中国临床研究2019，32，6： | 7 |
| 4 | Through-needle all-optical ultrasound imaging in vivo: a preclinical swine study显示文摘High-frequency ultrasound imaging can provide exquisite visualizations of tissue to guide minimally invasive procedures.Here,we demonstrate that an all-optical ultrasound transducer,through which light guided by optical fibers is used to generate and receive ultrasound,is suitable for real-time invasive medical imaging in vivo.Broad-bandwidth ultrasound generation was achieved through the photoacoustic excitation of a multiwalled carbon nanotube-polydimethylsiloxane composite coating on the distal end of a 300-μm multi-mode optical fiber by a pulsed laser.The interrogation of a high-finesse Fabry–Pérot cavity on a single-mode optical fiber by a wavelength-tunable continuous-wave laser was applied for ultrasound reception.This transducer was integrated within a custom inner transseptal needle(diameter 1.08 mm;length 78 cm)that included a metallic septum to acoustically isolate the two optical fibers.The use of this needle within the beating heart of a pig provided unprecedented realtime views(50 Hz scan rate)of cardiac tissue(depth:2.5 cm;axial resolution:64μm)and revealed the critical anatomical structures required to safely perform a transseptal crossing:the right and left atrial walls,the right atrial appendage,and the limbus fossae ovalis.This new paradigm will allow ultrasound imaging to be integrated into a broad range of minimally invasive devices in different clinical contexts. | Malcolm C Finlay Charles A Mosse Richard J Colchester Sacha Noimark Edward Z Zhang Sebastien Ourselin Paul C Beard Richard J Schilling Ivan P Parkin Ioannis Papakonstantinou Adrien E Desjardins | 2017 | Light(Science & Applications)2017，6，1： | 6 |
| 5 | Failed biliary cannulation: Clinical and technical outcomes after tertiary referral endoscopic retrograde cholangiopancreatography显示文摘AIM: Prospective evaluation of repeat endoscopic retrograde cholangiopancreatography (ERCP) for failed Schutz grade 1 biliary cannulation in a high-volume center. METHODS: Prospective intention-to-treat analysis of patients referred for biliary cannulation following recent unsuccessful ERCP. RESULTS: Fifty-one patients (35 female; mean age: 62.5 years; age range: 40-87 years) with previous failed biliary cannulation were referred for repeat ERCP. The indication for ERCP was primarily choledocholithiasis (45%) or pancreatic malignancy (18%). Successful biliary can- nulation was 100%. The precut needle knife sphincterotomy (NKS) rate was 27.4%. Complications occurred in 3.9% (post-ERCP pancreatitis). An identif iable reason for initial unsuccessful biliary cannulation was present in 55% of cases. Compared to a cohort of 940 nave pa-pilla patients (female 61%; mean age: 59.9 years; age range: 18-94 years) who required sphincterotomy over the same time period, there was no statistical difference in the cannulation success rate (100% vs 98%) or postERCP pancreatitis (3.1% vs 3.9%). Precut NKS use was more frequent (27.4% vs 12.7%) (P = 0.017). CONCLUSION: Referral to a high-volume center following unsuccessful ERCP is associated with high technical success, with a favorable complication rate, compared to routine ERCP procedures. | Michael P Swan Michael J Bourke Stephen J Williams Sina Alexander Alan Moss Rick Hope David Ruppin | 2011 | World Journal of Gastroenterology2011，17，45： | 6 |
| 6 | Treatment of Crohn's disease in pregnant women: Drug and multidisciplinary approaches显示文摘Inflammatory bowel disease affects a substantial number of women in their reproductive years. Pregnancy presents a number of challenges for clinicians and patients; the health of the baby needs to be balanced with the need to maintain remission in the mother. Historically, treatments for Crohn's disease(CD) were often discontinued during the pregnancy, or nursing period, due to concerns about teratogenicity. Fortunately, observational data has reported the relative safety of many agents used to treat CD, including 5-aminosalicylic acid, thiopurines, and tumor necrosis factor. Data on the long-term development outcomes of children exposed to these therapies in utero are still limited. It is most important that physicians educate the patient regarding the optimal time to conceive, discuss the possible risks, and together decide on the best management strategy. | Didia Bismara Cury Alan C Moss | 2014 | World Journal of Gastroenterology2014，20，27： | 5 |
| 7 | 海水淡化在锅炉补给水和工艺用水系统中的应用显示文摘 | Peter Moss Guido Maragliano | 2005 | 膜科学与技术2005，25，3： | 4 |
| 8 | 补体B因子是代谢综合征模型代谢与心血管特征的一个决定因素显示文摘补体B因子(complenment factor B,CFB)在2型糖尿病及心血管病患者脂肪组织及血清中水平升高,但与疾病发病机制的因果关系不明确。自发性高血压大鼠(spontaneously hypertensive rats,SHR)脂肪组织及血清中CFB也升高。为明确CFB在代谢综合征中的作用,研究者在SHR中敲除Cfb基因。 | 赵狄 练桂丽 Coan PM Barrier M Alfazema N Carter RN Marion de Procé S Dopico XC Garcia Diaz A Thomson A Jackson-Jones LH Moyon B Webster Z Ross D Moss J Arends MJ Morton NM Aitman TJ | 2017 | 中华高血压杂志2017，25，8： | 3 |
| 9 | Interrelationships amongst carcass and meat quality characteristics of sheep显示文摘 | N.J. Okeudo B.W. Moss | 2004 | Meat Science2004，，1： | 3 |
| 10 | Impact of inflammatory bowel disease activity and thiopurine therapy on birth weight: A meta-analysis显示文摘AIM To investigate the effect of disease activity or thiopurine use on low birth weight and small for gestational age in women with inflammatory bowel disease(IBD).METHODS Selection criteria included all relevant articles on the effect of disease activity or thiopurine use on the risk of low birth weight(LBW) or small for gestational age(SGA) among pregnant women with IBD. Sixtynine abstracts were identified,35 papers were full text reviewed and,only 14 of them met inclusion criteria. Raw data were extracted to generate the relative risk of LBW or SGA. Quality was assessed using the Newcastle Ottawa Scale.RESULTS This meta-analysis is reported according to PRISMA guidelines. Fourteen studies met inclusion criteria,and nine reported raw data suitable for meta-analysis. We found an increased risk ratio of both SGA and LBW in women with active IBD,when compared with women in remission: 1.3 for SGA(4 studies,95%CI: 1.0-1.6,P = 0.04) and 2.0 for LBW(4 studies,95%CI: 1.5-2.7,P < 0.0001). Women on thiopurines during pregnancy had a higher risk of LBW(RR 1.4,95%CI: 1.1-1.9,P = 0.007) compared with non-treated women,but when adjusted for disease activity there was no significant effect on LBW(RR 1.2,95%CI: 0.6-2.2,P = 0.6). No differences were observed regarding SGA(2 studies; RR 0.9,95%CI: 0.7-1.2,P = 0.5). CONCLUSION Women with active IBD during pregnancy have a higher risk of LBW and SGA in their neonates. This should be considered in treatment decisions during pregnancy. | Begona Gonzalez-Suarez Shreyashee Sengupta Alan C Moss | 2017 | World Journal of Gastroenterology2017，23，45： | 3 |
| 11 | Integrated sources of photon quantum states based on nonlinear optics显示文摘The ability to generate complex optical photon states involving entanglement between multiple optical modes is not only critical to advancing our understanding of quantum mechanics but will play a key role in generating many applications in quantum technologies.These include quantum communications,computation,imaging,microscopy and many other novel technologies that are constantly being proposed.However,approaches to generating parallel multiple,customisable bi-and multi-entangled quantum bits(qubits)on a chip are still in the early stages of development.Here,we review recent advances in the realisation of integrated sources of photonic quantum states,focusing on approaches based on nonlinear optics that are compatible with contemporary optical fibre telecommunications and quantum memory platforms as well as with chip-scale semiconductor technology.These new and exciting platforms hold the promise of compact,low-cost,scalable and practical implementations of sources for the generation and manipulation of complex quantum optical states on a chip,which will play a major role in bringing quantum technologies out of the laboratory and into the real world. | Lucia Caspani Chunle Xiong Benjamin J Eggleton Daniele Bajoni Marco Liscidini Matteo Galli Roberto Morandotti David J Moss | 2017 | Light(Science & Applications)2017，6，1： | 3 |
| 12 | 有机硅在洗去型护发产品中的应用显示文摘 | Brett Moss Vince Ungvary Sabrina Marchioretto | 2005 | 日用化学品科学2005，28，9： | 3 |
| 13 | The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XV. The long-term incidence of macular edema显示文摘 | R. Klein B.E. Klein S.E. Moss K.J. Cruickshanks | 1995 | Ophthalmology1995，，1： | 3 |
| 14 | 介电测井新技术与应用显示文摘介电测井仪通过地层电磁波测量能分析淡水环境储层,识别可流动油气。介电测井数据资料对分析稠油储层特别有用。一种新型仪器通过长时间的应用,正将新的生机带入介电测井技术。这一切都得益于最近开发的、用于评价碳酸盐岩结构和泥质对砂岩影响的频散技术。 | Romulo Carmona Eric Decoster Jim Hemingway Mehdi Hizem Laurent Mosse Tarek Rizk Dale Julander Jeffrey Little Tom McDonald Jonathan Mude | 2013 | 国外测井技术2013，，5： | 3 |
| 15 | Current Paradigm and Future Directions for Treatment of Helicobacter pylori Infection显示文摘 | Jason Ferreira Steven F. Moss | 2014 | Current Treatment Options in Gastroenterology2014，，： | 2 |
| 16 | The Crohn’s disease activity index (CDAI) is similarly elevated in patients with Crohn’s disease and in patients with irritable bowel syndrome显示文摘 | C. Lahiff P. Safaie A. Awais M. Akbari L. Gashin S. Sheth A. Lembo D. Leffler A. C. Moss A. S. Cheifetz | 2013 | Aliment Pharmacol Ther2013，，8： | 2 |
| 17 | Engineering and biological approaches to the restoration from eutrophication of shallow lakes in which aquatic plant communities are important components显示文摘 | Brian Moss | 1990 | Hydrobiologia1990，，1： | 2 |
| 18 | QT interval variability and spontaneous ventricular tachycardia or fibrillation in the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II patients显示文摘 | Mark C. Haigney Wojciech Zareba Philip J. Gentlesk Robert E. Goldstein Michael Illovsky Scott McNitt Mark L. Andrews Arthur J. Moss | 2004 | Journal of the American College of Cardiology2004，，： | 2 |
| 19 | Inspection of the human stomach using remote-controlled capsule endoscopy: a feasibility study in healthy volunteers (with videos)显示文摘 | Jutta Keller Christiane Fibbe Frank Volke Jeremy Gerber Alexander C. Mosse Meike Reimann-Zawadzki Elisha Rabinovitz Peter Layer Daniel Schmitt Viola Andresen Ulrich Rosien Paul Swain | 2011 | Gastrointestinal Endoscopy2011，，1： | 2 |
| 20 | Reduction and carburization of iron oxides for Fischer–Tropsch synthesis显示文摘The activation of iron oxide Fischer–Tropsch Synthesis(FTS) catalysts was investigated during pretreatment: reduction in hydrogen followed by carburization in either CO or syngas mixture, or simultaneously reduction and carburization in syngas. A combination of different complementary in situ techniques was used to gain insight into the behavior of Fe-based FTS catalysts during activation. In situ XRD was used to identify the crystalline structures present during both reduction in hydrogen and carburization. An increase in reduction rate was established when increasing the temperature. A complete reduction was demonstrated in the ETEM and a grain size dependency was proven, i.e. bigger grains need higher temperature in order to reduce. XPS and XAS both indicate the formation of a small amount of carbonaceous species at the surface of the bulk metallic iron during carburization. | Monia Runge Nielsen Asger Barkholt Moss Anton Simon Bjrnlund Xi Liu Axel Knop-Gericke Alexander YuKlyushin Jan-Dierk Grunwaldt Thomas LSheppard Dmitry EDoronkin Anna Zimina Thomas Eric Lyck Smitshuysen Christian Danvad Damsgaard Jakob Birkedal Wagner Thomas Willum Hansen | 2020 | Journal of Energy Chemistry2020，29，12： | 2 |
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