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| 1 | Polymorphism of -765G > C COX-2 is a risk factor for gastric adenocarcinoma and peptic ulcer disease in addition to H pylori infection:A study from northern India显示文摘AIM: To investigate -765G > C COX-2 polymorphism and H pylori infection in patients with gastric adenocarcinoma, peptic ulcer disease (PUD) and non- ulcer dyspepsia (NUD). METHODS: We enrolled 348 adult patients (62 gastric adenocarcinoma, 45 PUD and 241 NUD) undergoing upper gastrointestinal endoscopy at two referral centers between September, 2002 and May, 2007. H pylori infection was diagnosed when any of the four tests (RUT, culture, histopathology and PCR) were positive. Genotyping for -765G > C polymorphism of COX-2 was performed by PCR-RFLP analysis. RESULTS: Frequency of C carrier had significantassociation with gastric adenocarcinoma as compared to NUD [77.4% vs 29%, P < 0.001, odds ratio (OR) 8.20; 95% confidence interval (95% CI), 4.08-16.47] and PUD (77.4% vs 31.1%, P < 0.001; OR 8.04; 95% CI, 3.25-19.90). Risk of gastric adenocarcinoma was significantly higher in patients having C carrier with (OR 7.83; 95% CI 3.09-19.85) and without H pylori infection (OR 7.06; 95% CI, 2.61-19.09). Patients with C carrier and H pylori infection had significant risk for the development of PUD (P < 0.001; OR 5.65; 95% CI, 2.07-15.34). CONCLUSION: -765G > C COX-2 polymorphism with or without H pylori could be a marker for genetic susceptibility to gastric adenocarcinoma. COX-2 polymorphism in presence of H pylori infection might be useful in predicting the risk of PUD. | Ashish Saxena Kashi Nath Prasad Uday Chand Ghoshal Monty Roshan Bhagat Narendra Krishnani Nuzhat Husain | 2008 | World Journal of Gastroenterology2008，14，10： | 18 |
| 2 | Multiplex-CAPS技术及其在番茄遗传鉴定中的应用显示文摘应用Multiplex-PCR和CAPS(Cleaved amplified polymorphic sequence)原理研究建立了Mutiplex-CAPS技术。该技术包括:(1)在PCR扩增反应体系加入2对、3对或多对核苷酸引物,经30~40个扩增循环后得到每对引物的特异扩增片段;(2)应用同一种限制性内切酶消化这些不同引物经扩增后获得的特异片段;(3)琼脂糖凝胶电泳溴化乙锭染色检测酶切片段长度的多态性。利用该技术对番茄(Lycopersicon es-culentum)TA517及其近等基因系的分析表明,Multiplex-CAPS能同时检测2个、3个或多个CAPS标记的多态性,其效果等同于每个CAPS标记的多态性的叠加,重复性好,分析效率高,降低成本数倍。 | 王孝宣 杜永臣 朱德蔚 Luigi Monti S.Grandillo | 2003 | 园艺学报2003，30，6： | 10 |
| 3 | 瘤胃稀释率对蛋白质发酵和微生物生长效率的影响显示文摘采用连续培养系统的12个发酵罐进行2次培养试验,研究瘤胃稀释率(D)对于活体外蛋白质发酵和微生物生长效率的影响。6个瘤胃稀释率分别为每小时发酵液流出量占发酵罐体积的0.025,0.050,0.075,0.100,0.150和0.200倍。以大豆提取蛋白为试验日粮,随着D的提高,饲料干物质、有机物质和粗蛋白真消化率均呈二次曲线趋势下降。提高D导致发酵液pH值提高,NH3和挥发性脂肪酸(VFA)浓度下降。每个VFA摩尔比例随D的改变而变化,并表现出蛋白质发酵特征。微生物N日产生量和微生物生长效率随D的提高而显著提高。蛋白质发酵的最大微生物生长效率为每千克可消化有机物合成微生物N71.4g,其相对应的D为0.207/h。二次曲线模型适合于描述微生物生长效率。 | 孟庆翔 Monty S.Kerley | 1998 | 中国农业科学1998，31，3： | 6 |
| 4 | 大尺寸CFRP约束混凝土方柱的轴心抗压试验研究显示文摘试件的尺寸对于碳纤维增强塑料(CFRP)约束混凝土柱的性能具有重要影响,但目前在CFRP约束混凝土尺寸效应方面的研究基本上还处于空白.基于对7种不同倒角半径的大尺寸CFRP约束混凝土方柱的轴心抗压试验,获取了各组试件的破坏模式、抗压强度、应力-应变曲线、外包CFRP应变分布等基本力学性能,并与已有小尺寸试件的试验结果进行比较和分析.研究结果表明,试件的抗压强度随倒角半径比的增大而增大,外包CFRP对直角试件几乎无增强作用;所有试件的破坏都是由外包CFRP的拉断所导致,断裂位置均位于倒角范围内,应力集中的现象明显;约束效应比MCR可以较好地反映尺寸效应对抗压强度影响,试件尺寸的增大显著降低CFRP的约束效应;外包CFRP的极限应变低于其材性试验结果35%以上,明显大于对应的小试件试验结果;已有模型的计算结果与本试验的实测结果存在显著差异,故有必要考虑尺寸效应的影响. | 单波 蔡静 肖岩 Giorgio Monti | 2016 | 湖南大学学报(自然科学版)2016，43，3： | 6 |
| 5 | 栽培稻种间近等基因系杂种育性遗传及其基因定位显示文摘用粳型亚洲栽培稻品种 WAB56- 1 0 4与来自种间回交组合 WAB56- 1 0 4 /CG1 4∥ WAB56- 1 0 4 ///WAB56- 1 0 4的3个栽培稻种间近等基因系杂交、回交 ,对 3个 BC1F1群体的花粉及小穗育性遗传研究表明 ,育性遗传符合单位点孢子体 -配子体互作模型 ,来自非洲栽培稻的不育基因在与相同位点的亚洲栽培稻等位基因互作时 ,导致携带亚洲栽培稻等位基因的雌雄配子败育 ,而形成花粉及小穗的半不育 ,但本研究的 3个组合中 ,并未导致所有携带亚洲栽培稻等位基因的雌配子完全败育 ,其作用介于配子消除与花粉灭杀之间。用微卫星标记对这 3个群体的育性基因定位表明 ,它们都位于第 6染色体短臂末端 ,但 WAB450 - 2、WAB450 - 8携带的不育位点与紧密连锁的微卫星标记 RM1 90、RM1 33共分离 ,且很可能与 S1等位 ,而WAB450 - 7的不育基因则与位于相邻区间的 RM2 53呈松散连锁 ,可能与 WAB450 - 2、WAB450 - | 陶大云 徐鹏 李静 杨友琼 周家武 胡凤益 Monty P.JONES | 2003 | 中国水稻科学2003，17，1： | 5 |
| 6 | 大尺寸CFRP约束混凝土方柱落锤动态冲击试验研究显示文摘采用FRP增强的混凝土柱在使用过程中,可能受到轴向冲击荷载作用,但目前这方面的研究基本处于空白.通过对7组21个大尺寸CFRP约束混凝土方柱进行落锤轴向冲击试验,研究倒角半径r对约束柱抗冲击性能的影响.试验获取了锤头冲击力时程曲线、压缩变形时程曲线、FRP表面关键点的应变时程曲线和整个破坏过程的高速影像等信息.试验结果表明,CFRP约束混凝土方柱的破坏是由试件中部倒角位置处的CFRP被拉断所导致的,试件的破坏现象与倒角半径r有关;倒角半径r对约束柱的冲击性能有显著影响,r越大,冲击应力峰值和能量密度也越大;CFRP约束混凝土方柱的动力增大系数(DIF)随倒角半径比r.的增大而减小,基本成线性关系,在1.23-1.82之间. | 单波 刘波 肖岩 GIORGIO Monti | 2016 | 振动与冲击2016，35，20： | 5 |
| 7 | Aeromonas veronii biovar veronii and sepsis-infrequent complication of biliary drainage placement: A case report显示文摘BACKGROUND Aeromonas species are uncommon pathogens in biliary sepsis and cause substantial mortality in patients with impaired hepatobiliary function. Asia has the highest incidence of infection from Aeromonas,whereas cases in the west are rare.CASE SUMMARY We report the case of a 64-year-old woman with advanced pancreatic cancer and jaundice who manifested fever,abdominal pain,severe thrombocytopenia,anemia and kidney failure following the insertion of a percutaneous transhepatic biliary drainage. Blood culture results revealed the presence of Aeromonas veronii biovar veronii(A. veronii biovar veronii). After antibiotic therapy and transfusions,the life-threatening clinical conditions of the patient improved and she was discharged.CONCLUSION This was a rare case of infection,probably the first to be reported in West countries,caused by A. veronii biovar veronii following biliary drainage. A finding of Aeromonas must alert clinician to the possibility of severe sepsis. | Manlio Monti Arianna Torri Elena Amadori Alice Rossi Giulia Bartolini Chiara Casadei Giovanni Luca Frassineti | 2019 | World Journal of Clinical Cases2019，7，6： | 4 |
| 8 | Risk of hepatitis B virus reactivation in rheumatoid arthritis patients undergoing biologic treatment: Extending perspective from old to newer drugs显示文摘Hepatitis B virus(HBV) reactivation in rheumatoid arthritis(RA) patients undergoing biological therapy is not infrequent. This condition can occur in patients with chronic hepatitis B as well as in patients with resolved HBV infection. Current recommendations are mainlyfocused on prevention and management strategies of viral reactivation under tumor necrosis factor-α inhibitors or chimeric monoclonal antibody rituximab. In recent years, growing data concerning HBV reactivation in RA patients treated with newer biological drugs like tocilizumab and abatacept have cumulated. In this review, epidemiology, pathogenesis and natural history of HBV infection have been revised first, mainly focusing on the role that specific therapeutic targets of current biotechnological drugs play in HBV pathobiology; finally we have summarized current evidences from scientific literature, including either observational studies and case reports as well, concerning HBV reactivation under different classes of biological drugs in RA patients. Taking all these evidences into account, some practical guidelines for screening, vaccination, prophylaxis and treatment of HBV reactivation have been proposed. | Francesca De Nard Monica Todoerti Vittorio Grosso Sara Monti Silvia Breda Silvia Rossi Carlomaurizio Montecucco Roberto Caporali | 2015 | World Journal of Hepatology2015，7，3： | 3 |
| 9 | Microfluidic actuators based on temperature-responsive hydrogels显示文摘The concept of using stimuli-responsive hydrogels to actuate fluids in microfluidic devices is particularly attractive,but limitations,in terms of spatial resolution,speed,reliability and integration,have hindered its development during the past two decades.By patterning and grafting poly(N-isopropylacrylamide)PNIPAM hydrogel films on plane substrates with a 2μm horizontal resolution and closing the system afterward,we have succeeded in unblocking bottlenecks that thermo-sensitive hydrogel technology has been challenged with until now.In this paper,we demonstrate,for the first time with this technology,devices with up to 7800 actuated micro-cages that sequester and release solutes,along with valves actuated individually with closing and opening switching times of 0.6±0.1 and 0.25±0.15 s,respectively.Two applications of this technology are illustrated in the domain of single cell handling and the nuclear acid amplification test(NAAT)for the Human Synaptojanin 1 gene,which is suspected to be involved in several neurodegenerative diseases such as Parkinson’s disease.The performance of the temperature-responsive hydrogels we demonstrate here suggests that in association with their moderate costs,hydrogels may represent an alternative to the actuation or handling techniques currently used in microfluidics,that are,pressure actuated polydimethylsiloxane(PDMS)valves and droplets. | Loïc D'Eramo Benjamin Chollet Marie Leman Ekkachai Martwong Mengxing Li Hubert Geisler Jules Dupire Margaux Kerdraon Clémence Vergne Fabrice Monti Yvette Tran Patrick Tabeling | 2018 | Microsystems & Nanoengineering2018，4，1： | 3 |
| 10 | Ultrasonographic Quantitative Estimation of Hepatic Steatosis in Children With NAFLD显示文摘 | Angela Shannon Naim Alkhouri Christine Carter-Kent Lidia Monti Rita Devito Rocio Lopez Ariel E. Feldstein Valerio Nobili | 2011 | Journal of Pediatric Gastroenterology and Nutrition2011，，2： | 3 |
| 11 | Options for continuous radar Earth observations显示文摘Near Real Time(minutes or hours) radar imaging of ground targets located anywhere on an hemisphere, with or without interferometric coherence with previous passes, can be obtained with different solutions that are considered here. Geosynchronous systems, from the one proposed in 1978 by Tomiyasu to telecom satellite compatible solutions, and Low, Medium or Geosynchronous Earth Orbit constellations are discussed.Their benefits, problems, and sizes are briefly summarized, and a comparative table is presented. If interferometric coherence is requested, continuous imaging is obtained only if a very wide geostationary aperture is progressively scanned, eventually using a MIMO(Multiple Input Multiple Output) combination of several slow librating small satellites. Instead, fast librating, strip mapping, large geosynchronous satellites do provide high resolution imaging, but interferometry(and thus coherent change detection) is achievable only after a minimum delay of 12 h, i.e., when the target comes in sight without need to squint the antenna. Hence, both complex and simple systems reach full resolution interferometric imaging and thus coherent change detection capability only after 12 h. | Andrea MONTI GUARNIERI Fabio ROCCA | 2017 | Science China(Information Sciences)2017，60，6： | 2 |
| 12 | Recombination mechanisms and thermal droop in AlGaN-based UV-B LEDs显示文摘This paper reports a comprehensive analysis of the origin of the electroluminescence(EL)peaks and of the thermal droop in UV-B AlGaN-based LEDs.By carrying out spectral measurements at several temperatures and currents,(i)we extract information on the physical origin of the various spectral bands,and(ii) we develop a novel closed-form model based on the Shockley–Read–Hall theory and on the ABC rate equation that is able to reproduce the experimental data on thermal droop caused by non-radiative recombination through deep levels.In the samples under test,the three EL bands are ascribed to the following processes:band-to-band recombination in the quantum wells(main EL peak),a parasitic intra-bandgap radiative transition in the quantum well barriers,and a second defect-related radiative process in the p-AlGaN superlattice. | CARLO DE SANTI MATTEO MENEGHINI DESIREE MONTI JOHANNES GLAAB MARTIN GUTTMANN JENS RASS SVEN EINFELDT FRANK MEHNKE JOHANNES ENSLIN TIM WERNICKE MICHAEL KNEISSL GAUDENZIO MENEGHESSO ENRICO ZANONI | 2017 | Photonics Research2017，5，2： | 2 |
| 13 | Infection of peripheral mononuclear cells of infected patients 显示文摘 | Zignego AL Macchia D Monti M | 1992 | J Hepatol1992，15，： | 2 |
| 14 | The systemic inflammatory response syndrome in cirrhotic patients: Relationship with their in-hospital outcome显示文摘 | Massimo Cazzaniga Elena Dionigi Giulia Gobbo Alessia Fioretti Valentina Monti Francesco Salerno | 2009 | Journal of Hepatology2009，，3： | 2 |
| 15 | Long-term outcome of pancreatic function following oncological surgery in children:Institutional experience and review of the literature显示文摘BACKGROUND Pancreatic neoplasms are uncommon in children and in most cases they are benign or have low malignant potential.Pancreatoblastoma and solid pseudopapillary tumor are the most frequent types in early and late childhood,respectively.Complete resection,although burdened by severe complications,is the only curative treatment for these diseases.Pancreatic surgery may result in impaired exocrine and endocrine pancreatic function.However,limited data are available on the long-term pediatric pancreatic function following surgical resection.AIM To investigate endocrine and exocrine pancreatic function and growth after oncological pancreatic surgery in a pediatric series.METHODS A retrospective analysis of all pediatric patients who underwent surgery for pancreatic neoplasm in our Institution from January 31,2002 to the present was performed.Endocrine and exocrine insufficiency,auxological and fat-soluble vitamin status(A,D,E and clotting tests)were assessed at diagnosis and at every follow-up visit.Exocrine insufficiency was defined as steatorrhea with fecal elastase-1<200μg/g stool,while endocrine insufficiency was identified as onset of Diabetes or Impaired Glucose Tolerance.Growth was evaluated based on body mass index(BMI)z-score trend.RESULTS Sixteen patients(12 girls and 4 boys,mean age 10.7±5.3 years),were included.Nine patients(56%)had a neoplasm in the pancreatic head,4 in the body/tail,2 in the tail and 1 in the body.Histological findings were as follows:Solid pseudopapillary tumor in 10 patients(62.5%),insulinoma in 2 patients,neuroendocrine tumor in 2 patients and acinar cell carcinoma in 2 patients.The most frequent surgery was pancreaticoduodenectomy(50%).Exocrine failure occurred in 4 patients(25%)and endocrine failure in 2 patients(12.5%).Exocrine insufficiency occurred early(within 6 mo after surgery)and endocrine insufficiency later(8 and 10 years after surgery).Mean BMI z-score was 0.36±1.1 at diagnosis and 0.27±0.95 at the last assessment.Vitamin D was insufficient(<30 ng/mL)in 8 of the 16 patients during the follow-up period.Vitamins A,E and clotting test were into the normal ranges in all patients.CONCLUSION Careful and long-term monitoring should follow any pancreatic surgery,to recognize and promptly treat exocrine and endocrine pancreatic insufficiency,which can occur after surgery. | Giulia Bolasco Teresa Capriati Chiara Grimaldi Lidia Monti Maria Debora De Pasquale Ippolita Patrizia Patera Marco Spada Giuseppe Maggiore Antonella Diamanti | 2021 | World Journal of Clinical Cases2021，9，25： | 2 |
| 16 | MAINTENANCE BACILLUS CALMETTE-GUERIN IMMUNOTHERAPY FOR RECURRENT TA, T1 AND CARCINOMA IN SITU TRANSITIONAL CELL CARCINOMA OF THE BLADDER: A RANDOMIZED SOUTHWEST ONCOLOGY GROUP STUDY显示文摘 | DONALD L. LAMM BRENT A. BLUMENSTEIN JOHN D. CRISSMAN JAMES E. MONTIE JAMES E. GOTTESMAN BRUCE A. LOWE MICHAEL F. SAROSDY ROBERT D. BOHL H. BARTON GROSSMAN THOMAS M. BECK JOSEPH T. LEIMERT E. DAVID CRAWFORD | 2000 | The Journal of Urology2000，，4： | 2 |
| 17 | Chronic pancreatitis as presentation of Crohn's disease in a child显示文摘It is reported that a pancreatic disease may precede the diagnosis of inflammatory bowel disease(IBD) both in children and in adults.Idiopathic chronic pancreatitis,however,occasionally co-exists with the IBD,mainly at pediatric age.We report a case of a patient who progressively developed the features of a chronic pancreatitis,before the diagnosis of Crohn's Disease(CD).Ten months after the onset of the first episode of pancreatitis the patient developed bloody diarrhea,mucus stools and biochemical findings of inflammation.The colonoscopy revealed a diffuse colitis without involvement of the last loop and the gastroscopy showed inflammation of the iuxta-papillary area.The histological findings confirmed the diagnosis of CD that involved the colon and the duodenum.In conclusion,in children the idiopathic chronic pancreatitis may be an unusual presentation of CD.Thus,if other known cause of chronic pancreatitis are not found,a not invasive work up to exclude the IBD should be warranted.An early coincidental diagnosis of the IBD may delay the progression of the pancreatic disease. | Daniela Knafelz Fabio Panetta Lidia Monti Fiammetta Bracci Bronislava Papadatou Giuliano Torre Luigi Dall'Oglio Antonella Diamanti | 2013 | World Journal of Gastroenterology2013，19，31： | 2 |
| 18 | Ultrasonographic Quantitative Estimation of Hepatic Steatosis in Children With NAFLD显示文摘 | Angela Shannon Naim Alkhouri Christine Carter-Kent Lidia Monti Rita Devito Rocio Lopez Ariel E. Feldstein Valerio Nobili | 2011 | Journal of Pediatric Gastroenterology and Nutrition2011，，2： | 2 |
| 19 | Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water显示文摘 | Zoltan Jambrik Simonetta Monti Vincenzo Coppola Eustachio Agricola Gaetano Mottola Massimo Miniati Eugenio Picano | 2004 | The American Journal of Cardiology2004，，10： | 2 |
| 20 | Triglyeerides impair postischemie recovery in isolate hearts: roles of endothelin-land trimetazidine显示文摘 | Monti LD Allibardi S Piatti PM | 2001 | Am J Physiol Heart Cire Physiol2001，281，3： | 1 |
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