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| 1 | 干扰素调节因子5通过损伤胞葬作用控制动脉粥样硬化病变中的坏死核心形成显示文摘髓系细胞是动脉粥样硬化病变发展和易损斑块形成的核心。动脉吞噬细胞吸收凋亡细胞(胞葬作用)的能力受损,可促进病变生长并建立坏死核心。干扰素调节因子(interferon regulatory factor,IRF)5是髓系细胞功能的重要调节因子。该研究试图确定IRF5是否影响动脉粥样硬化病变的形成和表型。方法:通过两种互补模型,研究IRF5在动脉粥样硬化中的作用: | Seneviratne AN Edsfeldt AO Cole JE Kassiteridi C Swart M Park I Green P Khoyratty TE Saliba DG Goddard ME Sansom SN Goncalves I Krams R Udalova IA Monaco C 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，8： | 9 |
| 2 | Prevalence of bile reflux in gastroesophageal reflux disease patients not responsive to proton pump inhibitors显示文摘AIM:To determine the prevalence and characteristics of bile reflux in gastroesophageal reflux disease(GERD) patients with persistent symptoms who are non-responsive to medical therapy.METHODS:Sixty-five patients(40 male,25 female;mean age,50 ± 7.8 years) who continued to report symptoms after 8 wk of high-dose proton pump inhibitor(PPI) therapy,as well as 18 patients with Barrett's esophagus,were studied.All patients filled out symptom questionnaires and underwent endoscopy,manometry and combined pH-metry and bilimetry.RESULTS:There were 4 groups of patients:22(26.5%) without esophagitis,24(28.9%) grade A-B esophagitis,19(22.8%) grade C-D and 18(21.6%) Barrett's esophagus.Heartburn was present in 71 patients(85.5%) and regurgitation in 55(66.2%),with 44(53%) reporting simultaneous heartburn and regurgitation.The prevalence of pathologic acid reflux in the groups without esophagitis and with grades A-B and C-D esophagitis was 45.4%,66.6% and 73.6%,respectively.The prevalence of pathologic bilirubin exposure in these 3 groups was 53.3%,75% and 78.9%,respectively.The overall prevalence of bile reflux in non-responsive patients was 68.7%.Pathologic acid and bile reflux was observed in 22.7% and 58.1% of non-esophagitic patients and esophagitic patients,respectively.CONCLUSION:The high percentage of patients poorly responsive to PPI therapy may result from poor control of duodenogastroesophageal reflux.Many patients without esophagitis have simultaneous acid and bile reflux,which increases with increasing esophagitis grade. | Luigi Monaco Antonio Brillantino Francesco Torelli Michele Schettino Giuseppe Izzo Angelo Cosenza Natale Di Martino | 2009 | World Journal of Gastroenterology2009，15，3： | 8 |
| 3 | Laparoscopic calibrated total vs partial fundoplication following Heller myotomy for oesophageal achalasia显示文摘AIM:To compare the mid-term outcomes of laparoscopic calibrated Nissen-Rossetti fundoplication with Dor fundoplication performed after Heller myotomy for oesophageal achalasia.METHODS:Fifty-six patients(26 men,30 women;mean age 42.8±14.7 years)presenting for minimally invasive surgery for oesophageal achalasia,were enrolled.All patients underwent laparoscopic Heller myotomy followed by a 180°anterior partial fundoplication in 30 cases(group 1)and calibrated NissenRossetti fundoplication in 26(group 2).Intraoperative endoscopy and manometry were used to calibrate the myotomy and fundoplication.A 6-mo follow-up period with symptomatic evaluation and barium swallow was undertaken.One and two years after surgery,the patients underwent symptom questionnaires,endoscopy,oesophageal manometry and 24 h oesophago-gastric pH monitoring.RESULTS:At the 2-year follow-up,no significant difference in the median symptom score was observed between the 2 groups(P=0.66;Mann-WhitneyU-test).The median percentage time with oesophageal pH< 4 was significantly higher in the Dor group compared to the Nissen-Rossetti group(2;range 0.8-10 vs 0.35;range 0-2)(P<0.0001;Mann-WhitneyU-test).CONCLUSION:Laparoscopic Dor and calibrated Nissen-Rossetti fundoplication achieved similar results in the resolution of dysphagia.Nissen-Rossetti fundoplication seems to be more effective in suppressing oesophageal acid exposure. | Natale Di Martino Antonio Brillantino Luigi Monaco Luigi Marano Michele Schettino Raffaele Porfidia Giuseppe Izzo Angelo Cosenza | 2011 | World Journal of Gastroenterology2011，17，29： | 4 |
| 4 | HCV-Related Nervous System Disorders显示文摘 | Salvatore Monaco Sergio Ferrari Alberto Gajofatto Gianluigi Zanusso Sara Mariotto Domenico Sansonno | 2012 | Clinical and Developmental Immunology2012，，： | 4 |
| 5 | Investigation of compensatory postures with videofluoromanometry in dysphagia patients显示文摘AIM: To investigate the effectiveness of head compensatory postures to ensure safe oropharyngeal transit. METHODS: A total of 321 dysphagia patients were enrolled and assessed with videofluoromanometry (VFM). The dysphagia patients were classified as follows: safe transit; penetration without aspiration; aspiration before, during or after swallowing; multiple aspirations and no transit. The patients with aspiration or no transit were tested with VFM to determine whether compensatory postures could correct their swallowing disorder. RESULTS: VFM revealed penetration without aspiration in 71 patients (22.1%); aspiration before swallowing in 17 patients (5.3%); aspiration during swallowing in 32 patients (10%); aspiration after swallowing in 21 patients (6.5%); multiple aspirations in six patients (1.9%); no transit in five patients (1.6%); and safe transit in 169 patients (52.6%). Compensatory postures guaranteed a safe transit in 66/75 (88%) patients with aspiration or no transit. A chin-down posture achieved a safe swallow in 42/75 (56%) patients, a head-turned posture in 19/75 (25.3%) and a hyperextended head posture in 5/75 (6.7%). The compensatory postures were not effective in 9/75 (12%) cases. CONCLUSION: VFM allows the speech-language therapist to choose the most effective compensatory posture without a trial-and-error process and check the effectiveness of the posture. | Antonio Solazzo Luigi Monaco Lucia Del Vecchio Stefania Tamburrini Francesca Iacobellis Daniela Berritto Nunzia Luisa Pizza Alfonso Reginelli Natale Di Martino Roberto Grassi | 2012 | World Journal of Gastroenterology2012，18，23： | 3 |
| 6 | HCV-Related Central and Peripheral Nervous System Demyelinating Disorders显示文摘 | Sara Mariotto Sergio Ferrari Salvatore Monaco | 2014 | Inflammation & Allergy-Drug Targets2014，，5： | 2 |
| 7 | Development and validation of fast Real-Time PCR assays for species identification in raw and cooked meat mixtures显示文摘 | Cesare Cammà Marco Di Domenico Federica Monaco | 2011 | Food Control2011，，2： | 2 |
| 8 | Toll-like receptors and macrophage activation in atherosclerosis显示文摘 | Anusha N. Seneviratne Bawani Sivagurunathan Claudia Monaco | 2011 | Clinica Chimica Acta2011，，1： | 2 |
| 9 | Mean platelet volume and the extent of coronary artery disease: Results from a large prospective study显示文摘 | Giuseppe De Luca Matteo Santagostino Gioel Gabrio Secco Ettore Cassetti Livio Giuliani Elena Franchi Lorenzo Coppo Sergio Iorio Luca Venegoni Elisa Rondano Gabriele Dell’Era Claudia Rizzo Patrizia Pergolini Francesco Monaco Giorgio Bellomo Paolo Marino | 2009 | Atherosclerosis2009，，1： | 2 |
| 10 | Major complications following endovascular surgery of descending thoracic aorta 显示文摘 | Di Tommaso L Monaco M Mottola M et at | 2006 | Interact Cardiovasc Thorac Surg2006，5，6： | 1 |
| 11 | Multicentric reticulhistiocytosis 显示文摘 | Trotta F Castellino G Monaco AL | 2004 | Best Pract Res Clin Rheumatol2004，18，5： | 1 |
| 12 | Novel proline substitution mutations inkeratin 16 in two cases of pachyonychia congenita type l显示文摘 | Smith FJD Del Monaco M Steijlen PM | 1999 | Br J Dermatol1999，141，6： | 1 |
| 13 | Prevalence of sarcopenia and its association with osteoporosis in 313 older women following a hip fracture 显示文摘 | Di Monaco M Vallero F Di Monaco R | 2011 | Arch Gerontol Geriatr2011，52，： | 1 |
| 14 | Catalyst-free porous carbon cathode and ionic liquid for high efficiency, rechar- geable Li/O2 battery 显示文摘 | Soavi F Monaco S Mastragostino M | 2013 | J Power Sources2013，224，： | 1 |
| 15 | Minor bio- active dihydrophenanthrenes from Juncus ef fusus 显示文摘 | Dellagreca M Monaco P Previtera L | 1997 | J Nat Prod1997，60，： | 1 |
| 16 | Anthro- pogenic carbon distributions in the Atlantic Ocean: Data-based estimates from the Arctic to the Antarctic 显示文摘 | V~izquez-Rodriguez M Touratier F Lo Monaco C | 2009 | Biogeosciences2009，6，3： | 1 |
| 17 | Propionibacterium acnes and SAPHO syndrome:a case report and literature review显示文摘 | Colina M Lo Monaco A Khodeir M | 2007 | Clin Exp Rheumatol2007，25，3： | 1 |
| 18 | A relatively brief ex- posure to environmental enrichment after experimental traumat- ic brain injury confers long-term cognitive benefits 显示文摘 | Cheng JP Shaw KE Monaco CM | 2012 | J Neu- rotrauma2012，29，17： | 1 |
| 19 | Rooting of Alnus rubra cuttings 显示文摘 | Monaco P A T M Ching K K Ching | 1980 | Tree Planters'' Notes1980，31，3： | 1 |
| 20 | Personality and Psychopathological Profiles in Individuals Exposed to Mobbing显示文摘 | Girardi P Monaco E Prestigiacomo C | 2007 | Violence Victims2007，，22： | 1 |
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