|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prevalence of bile reflux in gastroesophageal reflux disease patients not responsive to proton pump inhibitors显示文摘AIM:To determine the prevalence and characteristics of bile reflux in gastroesophageal reflux disease(GERD) patients with persistent symptoms who are non-responsive to medical therapy.METHODS:Sixty-five patients(40 male,25 female;mean age,50 ± 7.8 years) who continued to report symptoms after 8 wk of high-dose proton pump inhibitor(PPI) therapy,as well as 18 patients with Barrett's esophagus,were studied.All patients filled out symptom questionnaires and underwent endoscopy,manometry and combined pH-metry and bilimetry.RESULTS:There were 4 groups of patients:22(26.5%) without esophagitis,24(28.9%) grade A-B esophagitis,19(22.8%) grade C-D and 18(21.6%) Barrett's esophagus.Heartburn was present in 71 patients(85.5%) and regurgitation in 55(66.2%),with 44(53%) reporting simultaneous heartburn and regurgitation.The prevalence of pathologic acid reflux in the groups without esophagitis and with grades A-B and C-D esophagitis was 45.4%,66.6% and 73.6%,respectively.The prevalence of pathologic bilirubin exposure in these 3 groups was 53.3%,75% and 78.9%,respectively.The overall prevalence of bile reflux in non-responsive patients was 68.7%.Pathologic acid and bile reflux was observed in 22.7% and 58.1% of non-esophagitic patients and esophagitic patients,respectively.CONCLUSION:The high percentage of patients poorly responsive to PPI therapy may result from poor control of duodenogastroesophageal reflux.Many patients without esophagitis have simultaneous acid and bile reflux,which increases with increasing esophagitis grade. | Luigi Monaco Antonio Brillantino Francesco Torelli Michele Schettino Giuseppe Izzo Angelo Cosenza Natale Di Martino | 2009 | World Journal of Gastroenterology2009，15，3： | 8 |
| 2 | Adenocarcinoma of gastric cardia in the elderly: Surgical problems and prognostic factors显示文摘AIM: To analyze retrospectively, our results about patients who underwent surgical treatment for adenocarcinoma of the cardia in relation to age, in order to evaluate surgical problems and prognostic factors.METHODS: From January 1987 to March 2003, 140 patients with adenocarcinoma of the cardia underwent resection in the authors' institution. They were divided into three groups with regard to age. Patients <70 and >60 year old (31) were excluded; we also excluded 18 out of 109 patients with poor general status or systemic metastases. So, we compared 51 elderly (≥ 70 year old)and 58 younger patients (≤ 60 year old). The treatment was esophagectomy for type Ⅰ tumors, and extended gastrectomy and distal esophagectomy for type Ⅱ and Ⅲ lesions.RESULTS: Laparotomy was carried out in 91 patients (83.4%), 38 in the elderly (74.5%) and 53 in younger patients (91.3%, P<0.05). Primary resection was performed in 811 cases (89%) without significant differences between the two groups. Postoperative death was higher in the elderly (12.1%) than the other group (4.1%, P<0.05), while morbidity was similar in both groups. A curative resection (R0) was performed in 59 patients (72.8%), 69.6% in the elderly and 75% in the younger group (P>0.05). The overall 3- and 5-year survival rates were 26.7% and 117.8% respectively for the elderly and 40.7% and 35.1% respectively for younger patients (P = 0.1544). Survival rates were significantly associated with R0 resection,pathological node-positive category and tumor differentiation in both groups.CONCLUSION: As the age of the general population increases, more elderly patients with gastric cardia cancer will be candidates for surgical resection. Age alone should not preclude surgical treatment in elderly patients with gastric cardia cancer and a tumor resection can be carried out safely. Certainly, we should take care in defining the surgical treatment in elderly patients, particularly as regarding the surgical approach; although the surgical approach does not influence the survival rate, the transhiatal way still remains the best one due, to the lower incidence of respiratory morbidity and thoracic pain. | Natale Di Martino Giuseppe Izzo Angelo Cosenza Guido Cerullo Francesco Torelli Antonio Brillantino Alberto del Genio | 2005 | World Journal of Gastroenterology2005，11，33： | 5 |
| 3 | A coherency recognition based on structural decomposition procedure显示文摘 | Enrico De Tuglie Silvio Marcello Iannone Francesco Torelli | 2008 | IEEE Transactions on Power Systems2008，23，2： | 1 |
| 4 | Load following control schemes for deregulated energy markets显示文摘 | Enrico De Tuglie Francesco Torelli | 2006 | IEEE Trans on Power Systems2006，214，： | 1 |
| 5 | Effect of Alginate Lyase on Biofilm-Grown Helicobacter pylori Probed by Atomic Force Microscopy显示文摘 | Alessandro Maiorana Francesca Bugli Massimiliano Papi Riccardo Torelli Gabriele Ciasca Giuseppe Maulucci Valentina Palmieri Margherita Cacaci Francesco Paroni Sterbini Brunella Posteraro Maurizio Sanguinetti Marco De Spirito Miriam Rafailovich | 2015 | International Journal of Polymer Science2015，，： | 1 |
| 6 | Clinical, Manometric, and Ultrasonographic Results of Pneumatic Balloon Dilatation vs. Lateral Internal Sphincterotomy for Chronic Anal Fissure: A Prospective, Randomized, Controlled Trial显示文摘 | Adolfo Renzi M.D. Ph.D. Domenico Izzo M.D. Giandomenico Sarno M.D. Pasquale Talento M.D. Francesco Torelli M.D. Ph.D. Giuseppe Izzo M.D. Natale Martino M.D | 2008 | Diseases of the Colon & Rectum2008，，1： | 1 |
| 7 | Combined Laparoscopic-Endoscopic 'Rendez-vous' Procedure for Minimally Invasive Resection of Gastrointestinal Stromal Tumors of the Stomach显示文摘 | Marano Luigi Torelli Francesco Schettino Michele Porfidia Raffaele Reda Gianmarco Grassia Michele Braccio Bartolomeo Petrillo Marianna Di Martino Natale | 2011 | The American Surgeon2011，，8： | 1 |
| 8 | Large symptomatic gastric diverticula:Two case reports and a brief review of literature显示文摘Gastric diverticula are rare and uncommon conditions.Most gastric diverticula are asymptomatic.When symptoms arise,they are most commonly upper abdominal pain,nausea and emesis,while dyspepsia and vomiting are less common.Occasionally,patients with gastric diverticula can have dramatic presentations related to massive bleeding or perforation.The diagnosis may be difficult,as symptoms can be caused by more common gastrointestinal pathologies and only aggravated by diverticula.The appropriate management of diverticula depends mainly on the symptom pattern and as well as diverticulum size.There is no specific therapeutic strategy for an asymptomatic diverticulum.Although some authors support conservative therapy with antacids,this provides only temporary symptom relief since it is not able to resolve the underlying pathology.Surgical resection is the mainstay of treatment when the diverticulum is large,symptomatic or complicated by bleeding,perforation or malignancy,with over two-thirds of patients remaining symptom-free after surgery,while laparoscopic resection,combined with intraoperative endoscopy,is a safe and feasible approach with excellent outcomes.Here,we present two cases of uncommon large symptomatic gastric diverticula with a discussion of the cornerstones in management and report a minimally invasive solution,with a brief review of the literature. | Luigi Marano Gianmarco Reda Raffaele Porfidia Michele Grassia Marianna Petrillo Giuseppe Esposito Francesco Torelli Angelo Cosenza Giuseppe Izzo Natale Di Martino | 2013 | World Journal of Gastroenterology2013，19，36： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员