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| 1 | Evaluation of thermal water in patients with functional dyspepsia and irritable bowel syndrome accompanying constipation显示文摘瞄准:与机能性消化不良或伴随占优势的便秘的急躁的肠症候群(IBS ) 在病人评估水补充治疗的功效。方法:有机能性消化不良的 3872 个病人和有急躁的肠症候群的 3609 个病人的一个总数被 18 个 Italina 热中心在学习注册。病人们为 21 d 经历了热治疗的第一个周期。一年以后,病人们在一样的中心被重新估计并且收到了热治疗的另一个周期。在社会、职业的地位,家庭和病理学的病历,生活方式,临床的记录,福利的利用和健康结构和设备上收集个人数据的一张问询表在各热的治疗以后在基础时间和一年予每个病人被以。有机能性消化不良的六十个病人并且 20 由呼吸测试分析与 IBS 和 80 健康控制收到了胃的输出和 oro 盲肠的运输时间的评估。呼吸测试在基础时间并且在水补充治疗以后被执行。胃肠的症状同时被评估点。呼吸样品与集体 spectometer 和 gascromatograph 被分析。结果为呼吸测试的 octanoic 和 lactulose 呼吸测试的同样 oro 盲肠的运输时间被表示为 T (1/2 ) 和 T 落后。结果:症状的流行的重要减小在热治疗的第一和第二个周期的结束被观察在消化不良并且 IBS 病人。变化的分析出现了一真实并且在所有病人坚持症状的蚂蚁改进。在为 3 wk 的水补充以后,胃的输出的减小在 49 被观察(87.5%) 56 个消化不良的病人。T (1/2 ) 和 T 落后显著地与基础价值相比在治疗以后被减少[91 +/- 12 T (1/2 ) 和 53 +/- 11 (T 落后) ,搁置 1 和 2 ] 与类似于健康题目的 octanoic 呼吸测试的结果。在为 3 wk 的水补充以后, oro 盲肠的运输时间在学习的开始是比那短的。结论:为伴随 IBS 的机能性消化不良或便秘的矿水补充治疗能改进胃的酸输出和肠的运输时间。 | Giovanni Gasbarrini Marcello Candelli RiccardoGiuseppe Graziosetto Sergio Coccheri Ferdinando Di Iorio Giuseppe Nappi | 2006 | World Journal of Gastroenterology2006，12，16： | 12 |
| 2 | Wilson's disease: Prospective developments towards new therapies显示文摘Wilson's disease(WD) is an autosomal recessive disorder of copper metabolism, caused by mutations in the ATP7 B gene. A clear demand for novel WD treatment strategies has emerged. Although therapies using zinc salts and copper chelators can effectively cure WD, these drugs exhibit limitations in a substantial pool of WD patients who develop intolerance and/or severe side effects. Several lines of research have indicated intriguing potential for novel strategies and targets for development of new therapies. Here, we review these new approaches, which comprise correction of ATP7 B mutants and discovery of new compounds that circumvent ATP7B-deficiency, as well as cell and gene therapies. We also discuss whether and when these new therapeutic strategies will be translated into clinical use, according to the key requirements for clinical trials that remain to be met. Finally, we discuss the hope for the current rapidly developing research on molecular mechanisms underlying WD pathogenesis and for the related potential therapeutic targets to provide a solid foundation for the next generation of WD therapies that may lead to an effective, tolerable and safe cure. | Giusy Ranucci Roman Polishchuck Raffaele Iorio | 2017 | World Journal of Gastroenterology2017，23，30： | 6 |
| 3 | Management of cholelithiasis in Italian children:A national multicenter study显示文摘AIM:To evaluate the management of Italian children with cholelithiasis observed at Pediatric and Surgical Departments linked to Italian Society of Pediatric Gastroenterology Hepatology and Nutrition. METHODS: One-hundred-eighty children (90 males, median age at diagnosis 7.3 years; range, 0-18 years) with echographic evidence of cholelithiasis were enrolled in the study; the data were collected by an anonymous questionnaire sent to participating centers. RESULTS: One hundred seventeen patients were treated with ursodeoxycholic acid; in 8 children dissolution of gallstones was observed, but the cholelithiasis recurred in 3 of them. Sixty-five percent of symptomatic children treated became asymptomatic. Sixty-four patients were treated with cholecystectomy and in only 2 cases a postoperative complication was reported. Thirty- four children received no treatment and were followed with clinical and echographic controls; in no case thedevelopment of complications was reported. CONCLUSION: The therapeutic strategies were extremely heterogeneous. Ursodeoxycholic acid was ineffective in dissolution of gallstones but it had a positive effect on the symptoms. Laparoscopic cholecystectomy was confirmed to be an efficacy and safe treatment for pediatric gallstones. | Claudia Della Corte Diego Falchetti Gabriella Nebbia Marisa Calacoci Maria Pastore Ruggiero Francavilla Matilde Marcellini Pietro Vajro Raffaele Iorio | 2008 | World Journal of Gastroenterology2008，14，9： | 6 |
| 4 | Water resource applications with RADARSAT-2-a preview显示文摘Fresh water is arguably the most vital resource for many aspects of a healthy and stable environment.Monitoring the extent of surface water enables resource managers to detect perturbations and long term trends in water availability,and set consumption guidelines accordingly.Potential end-users of water-related observations are numerous and reflect society as a whole.They encompass scientists and managers at all levels of government,aboriginal groups,water/power utility managers,farmers,planners,engineers,hydrologists,medical researchers,climate scientists,recreation enthusiasts,public school to postgraduate students,many special interest groups and the general public.Water data and analyses generate information products that benefit water resources planning and management,engineering design,plant operations,navigation activities,health research,water quality assessments and ecosystem management.As well,they serve as inputs for flood and drought warnings and weather and climate prediction models.Radar data in general,and RADARSAT in particular,are very good for detecting open surface water and have been used operationally for flood monitoring in many countries.Significant radar data archives now exist to analyse seasonal,annual and decadal trends,in order to attain a better understanding of the freshwater cycle.Radar data are also useful for wetland classification and soil moisture estimation.With the increasing pressure on water resources,both from a quality as well as a quantity perspective,the need will continue to increase for reliable information.RADARSAT-2 has several innovations that will enhance the ability to provide useful information about water resources.This paper provides an overview of the use of radar in general,and RADARSAT-2 in particular,for the generation of information products useful to water resource managers. | B.Brisco R.Touzi J.J.van der Sanden F.Charbonneau T.J.Pultz M.D’Iorio | 2008 | International Journal of Digital Earth2008，1，1： | 4 |
| 5 | Analysis of AKS- and lanthana-doped molybdenum wire显示文摘 | L.E. Iorio B.P. Bewlay M. Larsen | 2005 | International Journal of Refractory Metals and Hard Materials2005，，4： | 2 |
| 6 | Intravascular large B-cell lymphoma presenting as slowly progressive paraparesis with normal MRI features显示文摘 | Chiara De Fino Vincenzo Arena Stefan Hohaus Riccardo Di Iorio Valentina Bozzoli Massimiliano Mirabella | 2011 | Journal of the Neurological Sciences2011，，1： | 2 |
| 7 | microRNA involvement in human cancer显示文摘 | Marilena V. Iorio Carlo M. Croce | 2012 | Carcinogenesis2012，，6： | 2 |
| 8 | Chest pain caused by multiple exostoses of the ribs: A case report and a review of literature显示文摘The aim of this paper is to report an exceptional case of multiple internal exostoses of the ribs in a young patient affected by multiple hereditary exostoses(MHE) coming to our observation for chest pain as the only symptom of an intra-thoracic localization. A 16 years old patient with familiar history of MHE came to our observation complaining a left-sided chest pain. This pain had increased in the last months with no correlation to a traumatic event. The computed tomography(CT) scan revealed the presence of three exostoses located on the left third, fourth and sixth ribs, all protruding into the thoracic cavity, directly in contact with visceral pleura. Moreover, the apex of the one located on the sixth rib revealed to be only 12 mm away from pericardium. Patient underwent video-assisted thoracoscopy with an additional 4-cm mini toracotomy approach. At the last 1-year followup, patient was very satisfied and no signs of recurrence or major complication had occured. In conclusion, chest pain could be the only symptom of an intra-thoracic exostoses localization, possibly leading to serious complications. Thoracic localization in MHE must be suspected when patients complain chest pain. A chest CT scan is indicated to confirm exostoses and to clarify relationship with surrounding structures. Video-assisted thoracoscopic surgery can be considered a valuable option for exostoses removal, alone or in addiction to a mini-thoracotomy approach, in order to reduce thoracotomy morbidity. | Daniele Mazza Mattia Fabbri Cosma Calderaro Carlo Iorio Luca Labianca Camilla Poggi Francesco Turturro Antonello Montanaro Andrea Ferretti | 2017 | World Journal of Orthopedics2017，8，5： | 2 |
| 9 | Helicobacter pylori free‐living and biofilm modes of growth: behavior in response to different culture media显示文摘 | Lucinda J. Bessa Rossella Grande Donato DI Iorio Mara DI Giulio Emanuela DI Campli Luigina Cellini | 2012 | APMIS2012，，6： | 2 |
| 10 | 儿童高转氨酶血症是遗传性肝病的一个标志 | Iorio R. Sepe A. Giannattasio A. 廖新华 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，0，1： | 2 |
| 11 | Mean platelet volume and the extent of coronary artery disease: Results from a large prospective study显示文摘 | Giuseppe De Luca Matteo Santagostino Gioel Gabrio Secco Ettore Cassetti Livio Giuliani Elena Franchi Lorenzo Coppo Sergio Iorio Luca Venegoni Elisa Rondano Gabriele Dell’Era Claudia Rizzo Patrizia Pergolini Francesco Monaco Giorgio Bellomo Paolo Marino | 2009 | Atherosclerosis2009，，1： | 2 |
| 12 | Shape memory composite structures for self-deployable solar sails显示文摘Shape memory composites(SMCs)combine mechanical performances of composite materials with functional behavior of shape memory polymers.They can be used to produce the external frame of self-deployable solar sails with very low weight in comparison with traditional composite booms.Furthermore,heat activation is necessary for deploying instead of complex mechanical devices.In this study,the mechanical behavior of a solar sail with SMC frame is simulated by means of finite element modeling.Design considerations are made on sail deployment configuration,size/weight ratio of solar sails,and SMC properties.An experimental activity has been also performed to provide suitable candidates for the composite laminates of the SMC structure.Mechanical and instrumented recovery tests have been carried out on 2-plies carbon-fiber laminates with a shape memory interlayer. | Loredana Santo Denise Bellisario Leamdro Iorio Fabrizio Quadrini | 2019 | Astrodynamics2019，3，3： | 2 |
| 13 | Adrenomedullin is increased in the fetoplacental circulation in intrauterine growth restriction with abnormal umbilical artery waveforms显示文摘 | Di Iorio R Marinoni E Letizia C | 2000 | Am J Obstet Gynecol2000，182，3： | 1 |
| 14 | MicroRNA gene expression deregulation in human breast cancer 显示文摘 | Iorio MV Ferracin M Liu CG | 2005 | Cancer Res2005，65，16： | 1 |
| 15 | Immunohistochemical expression of P53,nm23-HI,Ki67 and DNA ploidy:correlation with lymph node status and other clinical pathologic parameters in breast cancer显示文摘 | Midulla C De Iorio P Nagar | 1999 | Anticancer Res1999，19，5： | 1 |
| 16 | Surgical treatment of displaced femoral neck fractures in the elderly: a survey of the American Associ- ation of Hip and Knee Surgeons显示文摘 | Iorio R Schwartz B Macaulay W | 2006 | J Arthroplasty2006，8，： | 1 |
| 17 | MicroRNA gene expression deregulation in human breast cancer显示文摘 | Iorio MV Ferracin M Liu CG | 2005 | Cancer Res2005，65，16： | 1 |
| 18 | MicroRNA gene expression deregulation in human breast cancer显示文摘 | Iorio M V Ferracin M Liu C G | 2005 | Cancer Res2005，65，16： | 1 |
| 19 | CDw150(SLAM) is a receptor for lymphotropic strains of measles virus and may account for the immunosuppressive properties of this virus显示文摘 | Hsu E C Iorio C Sarangi F | 2001 | Virology2001，279，： | 1 |
| 20 | MicroRNA gene ex- pression deregulation in human breast caneer显示文摘 | Iorio M V Ferracin M Liu C G | 2005 | Cancer Res2005，65，16： | 1 |
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