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| 1 | Decoding altitude-activated regulatory mechanisms occurring during apple peel ripening显示文摘Apple(Malus domestica Borkh)is an important fruit crop cultivated in a broad range of environmental conditions.Apple fruit ripening is a physiological process,whose molecular regulatory network response to different environments is still not sufficiently investigated and this is particularly true of the peel tissue.In this study,the influence of environmental conditions associated with low(20 m)and high(750 m)altitude on peel tissue ripening was assessed by physiological measurements combined with metabolomic and proteomic analyses during apple fruit development and ripening.Although apple fruit ripening was itself not affected by the different environmental conditions,several key color parameters,such as redness and color index,were notably induced by high altitude.Consistent with this observation,increased levels of anthocyanin and other phenolic compounds,including cyanidin-3-O-galactoside,quercetin-3-O-rhamnoside,quercetin-3-O-rutinoside,and chlorogenic acid were identified in the peel of apple grown at high altitude.Moreover,the high-altitude environment was characterized by elevated abundance of various carbohydrates(e.g.,arabinose,xylose,and sucrose)but decreased levels of glutamic acid and several related proteins,such as glycine hydroxymethyltransferase and glutamate–glyoxylate aminotransferase.Other processes affected by high altitude were the TCA cycle,the synthesis of oxidative/defense enzymes,and the accumulation of photosynthetic proteins.From the obtained data we were able to construct a metabolite-protein network depicting the impact of altitude on peel ripening.The combined analyses presented here provide new insights into physiological processes linking apple peel ripening with the prevailing environmental conditions. | Evangelos Karagiannis Michail Michailidis Georgia Tanou Federico Scossa Eirini Sarrou George Stamatakis Martina Samiotaki Stefan Martens Alisdair R.Fernie Athanassios Molassiotis | 2020 | Horticulture Research2020，7，1： | 3 |
| 2 | A qualitative exploration of a respiratory distress symptom cluster in lung cancer: Cough, breathlessness and fatigue显示文摘 | Molassiotis A Lowe M Blackball F | 2011 | Lung Cancer2011，71，1： | 1 |
| 3 | Psychometric evaluation of the Chinese version of Mishels uncertainty in illness scale显示文摘 | Ruth Taylor-Poliae Alexander Molassiotis | 2000 | Hong Kong Nursing Journal2000，36，4： | 1 |
| 4 | Exploring the scope of ontology specialist nurses practice in the UK 显示文摘 | Farrell C Molassiotis A Beaver K | 2011 | Eur J Oncol Nurs2011，15，2： | 1 |
| 5 | Evaluation of burnout and job satisfaetion in marrow transplant nurses显示文摘 | Molassiotis A Haberman M | 1996 | Caneer Nuts1996，19，5： | 1 |
| 6 | Dietary and fluid compliance in Chinese he- modialysis patients 显示文摘 | Lee SH Molassiotis A | 2002 | Int J Nurs Stud2002，39，7： | 1 |
| 7 | A Review of Patient Self-Report to Tools for Chemotherapy-Induced Nausea and Vomiting显示文摘 | Brearley S G Clements C V Molassiotis A | 2008 | Support Care Cancer2008，16，11： | 1 |
| 8 | A systematic review of complementary and alternative medicine interventions for the management of cancer - related fatigue 显示文摘 | Finnegan - John Jennifer Molassiotis Alex Richardson Alison | 2013 | Integr Cancer T her2013，12，4： | 1 |
| 9 | The effect of progressive muscle relaxation training on anxiety and quality of life after stoma surgery in colorectal cancer patients显示文摘 | Cheung Y L Molassiotis A Chang A M | | 0，，03： | 1 |
| 10 | Polyamines reprogram oxidative and nitrosative status and the proteome of citrus plants exposed to salinity stress显示文摘 | GEORGIA TANOU VASILEIOS ZIOGAS MAYA BELGHAZI ANASTASIS CHRISTOU PANAGIOTA FILIPPOU DOMINIQUE JOB VASILEIOS FOTOPOULOS ATHANASSIOS MOLASSIOTIS | 2014 | Plant Cell Environ2014，，4： | 1 |
| 11 | The relationship between diabetes knowledge and compliance among Chinese with non-insulin dependent diabetes mellitus in Hong Kong 显示文摘 | Chan Y M Molassiotis A | 1999 | J Adv Nurs1999，30，2： | 1 |
| 12 | Analysis of aprepitant for prevention of chemotherapy-induced nausea and vomiting with moderately and highly emetogenic chemotherapy 显示文摘 | Molassiotis A Nguyen AM Rittenberg CN | 2013 | Future Oncol2013，9，10： | 1 |
| 13 | A randomized, controlled trial of acupuncture self- needling as maintenance therapy for cancer-re- lated fatigue after therapist-delivered acupuncture 显示文摘 | Molassiotis A Bardy J Finnegan-John J | 2013 | Ann Oncol2013，24，6： | 1 |
| 14 | Dietary and fluid compliance in Chinese hemodialysis patients显示文摘 | Lee SH Molassiotis A | 2002 | Int J Nurs Stud2002，39，7： | 1 |
| 15 | Dietary and fluid compliance in Chinese hemodialysis patients显示文摘 | Lee S H Molassiotis A | 2002 | Int J Nurs Stud2002，39，7： | 1 |
| 16 | The effect of progressive muscle relaxation training on anxiety and quality of life after stoma surgery in colorectal cancer patients 显示文摘 | Cheung YL Molassiotis A Chang AM | 2003 | Psychooncology2003，12，3： | 1 |
| 17 | A prospective observational study of chemotherapy-related nausea and vomiting in routine practice in a UK cancer centre显示文摘 | Molassiotis A Saunders MP Valle J | 2008 | Support Care Cancer2008，16，2： | 1 |
| 18 | Use of complementary and alternative medicine in cancer patients:a European survey显示文摘 | Molassiotis A Fernadez-Ortega P Pud D Ozden G Scott JA Panteli V Margulies A Browall M Magri M Selvekerova S Madsen E Milovics L Bruyns I Gudmundsdottir G Hummerston S Ahmad AM Platin N Keamey N Patiraki E | | 0，，04： | 1 |
| 19 | Managing nausea and vomiting after cancer treatments: patients still suffer unnecessarily 显示文摘 | Molassiotis A | 2005 | EurJ OncolNurs2005，9，1： | 1 |
| 20 | A systematic review of worldwide cancer nursing research: 1994 to 2003显示文摘 | Molassiotis A Gibson F Kelly D | 2006 | Cancer Nurs2006，29，6： | 1 |
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