|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The role and modulation of autophagy in experimental models of myocardial ischemia-reperfusion injury显示文摘称为 autophagy 品质上的一个生理的序列由移开蛋白质总数和损坏细胞质的成分决定细胞的生存能力,并且显著地作出贡献到心肌的 ischemia-reperfusion (I/R ) 的度损害。这紧安排的分解代谢的细胞的 ‘ housekeeping’过程向房间提供精力的新来源适应紧张的条件。当支持幸存的机制,而是增加的证据建议它能也导致房间的遗赠,这个过程首先被描述。Autophagy 包括心肌的 I/R 损害在多重心脏的条件的致病被含有。然而,争论至于 autophagy 是否充当保护的机制或在心贡献 I/R 损害的有害效果坚持。这争吵可以在试验性的模型和种包括可变性源自几个因素,并且方法论过去常估计 autophagy。这评论在向操作 autophagy 显著地在压力大多数的条件下面增加心脏的 myocytes 的幸存受到 I/R,和成长兴趣的孤立的心脏的房间在 autophagy 的调整和角色上提供更新的知识是 I/R 损害。这的不安 evolutionarily 保存了细胞内部的清洁的 autophagy 机制,由指向的调整通过在其它之中, rapamycin ( mTOR )的哺乳动物的目标禁止者,腺苷 激活monophosphate 的蛋白质 kinase ( AMPK )调节的人,钙降低代理人, resveratrol , longevinex , sirtuin 使活跃之物, proapoptotic 基因 Bnip3 , IP3 和 lysosome 禁止者,可以对 I/R 授与抵抗到心房间导致的房间死亡。因此,在质问心肌层的 autophagy 的治疗学的操作可以有益于梗塞以后的心脏的愈合并且改变。 | Carol Chen-Scarabelli Pratik R. Agrawal Louis Saravolatz Cadigia Abuniat Gabriele Scarabelli Anastasis Stephanou Leena Loomba Jagat Narula Tiziano M. Scarabelli Richard Knight | 2014 | Journal of Geriatric Cardiology2014，11，4： | 37 |
| 2 | Magnetic resonance imaging in the assessment of brain involvement in alcoholic and nonalcoholic Wernicke's encephalopathy显示文摘AIM To present the typical and atypical magnetic resonance(MR) imaging findings of alcoholic and non-alcoholic Wernicke's encephalopathy.METHODS This study included 7 patients with Wernicke's encephalopathy(2 men, 5 women; mean age, 52.3 years) that underwent brain MR examination between January 2012 and March 2016 in a single institution. Three patients were alcoholics and 4 patients were non-alcoholics. MR protocol included a T2-weighted sequence, a fluid attenuation inversion recovery(FLAIR) sequence, a diffusion-weighted sequence(b = 0 and 1000 s/mm^2), and a contrast-enhanced MR sequence. All MR images were retrospectively reviewed at baseline and follow-up by two radiologists.RESULTS All patients with Wernicke's encephalopathy had bilateral areas showing high signal intensity on both T2-weighted and FLAIR MR images in the typical sites(i.e., the periaqueductal region and the tectal plate). Signal intensity abnormalities in the atypical sites(i.e., the cerebellum and the cerebellar vermis) were seen in 4 patients, all of which had no history of alcohol abuse. Six patients had areas with restricted diffusionin the typical and atypical sites. Four patients had areas showing contrast-enhancement in the typical and atypical sites. Follow-up MR imaging within 6 mo after therapy(intravenous administration of thiamine) was performed in 4 patients, and demonstrated a complete resolution of all the signal intensities abnormalities previously seen in all patients. CONCLUSION MR imaging is valuable in the diagnosis of Wernicke's encephalopathy particularly in patients presenting with atypical clinical symptoms, or with no history of alcohol abuse. | Gianvincenzo Sparacia Andrea Anastasi Claudia Speciale Francesco Agnello Aurelia Banco | 2017 | World Journal of Radiology2017，9，2： | 4 |
| 3 | 希腊城市患者人群研究显示雌激素受体(α和β受体)而非雄激素受体的表达水平与局限性晚期前列腺癌(T3NOMO)术后复发、进展和生存具有相关性显示文摘本文旨在研究一希腊城区局限性晚期前列腺癌(T3NOMO)根治术后患者人群,评估雌激素受体(α和β受体)和雄激素受体在术后生化复发、进展和死亡中的预后价值。本研究回顾性分析了100名行根治性前列腺切除术后病理分期为T3NOM0的前列腺癌患者。患者平均年龄和随访期限分别为62岁和6年。使用组织化学评分方法对受体的免疫反应性进行半定量分析。依据患者术后的复发、进展和生存率指标评估α、β雌激素受体和雄激素受体的预后价值。结果显示雄激素受体和以上指标均无关联,而α、β雌激素受体和预后均有相关性。单变量Cox回归分析显示预测因素中α雌激素受体表达增高与预后风险增高有显著相关性,β雌激素受体增高与预后风险降低有显著相关性,当联合α、β雌激素受体表达情况进行评估,α雌激素受体高表达或β雌激素受体低表达的患者与α雌激素受体阴性表达合并β受体组织化学评分1.7以上的患者相比,前列腺癌生化复发、进展或死亡的风险分别增加了6.03,10.93和10.53倍。多因素CoxLt例风险模型分析显示年龄、术前PSA水平、Gleason评分和雌激素受体是所有预后指标的独立预测因子。雌激素受体的表达水平是病理分期T3NOMO前列腺癌术后患者预后的重要预测因子。相比之下,雄激素受体的预测价值有限。 | Georgios Megas Michael Chrisofos Ioannis Anastasiou Aida Tsitlidou Theodosia Choreftaki Charalampos Deliveliotis | 2015 | Asian Journal of Andrology2015，17，1： | 4 |
| 4 | Symptom Management for Irritable Bowel Syndrome: A Pilot Randomized Controlled Trial of Acupuncture/Moxibustion显示文摘 | Joyce K. Anastasi Donald J. McMahon Gee H. Kim | 2009 | Gastroenterology Nursing2009，，4： | 3 |
| 5 | Value of serial magnetic resonance imaging in the assessment of brain metastases volume control during stereotactic radiosurgery显示文摘AIM To evaluate brain metastases volume control capabilities of stereotactic radiosurgery(SRS) through serial magnetic resonance(MR) imaging follow-up. METHODS MR examinations of 54 brain metastases in 31 patients before and after SRS were reviewed. Patients were included in this study if they had a pre-treatment MR examination and serial follow-up MR examinations at 6 wk, 9 wk, 12 wk, and 12 mo after SRS. The metastasis volume change was categorized at each follow-up as increased(> 20% of the initial volume), stable(± 20% of the initial volume) or decreased(< 20% of the initial volume). RESULTS A local tumor control with a significant(P < 0.05) volume decrease was observed in 25 metastases at 6-wk follow-up. Not significant volume change was observed in 23 metastases and a significant volume increase was observed in 6 metastases. At 9-wk followup, 15 out of 25 metastases that decreased in size at 6 wk had a transient tumor volume increase, followed by tumor regression at 12 wk. At 12-wk follow-up there was a significant reduction in volume in 45 metastases, and a significant volume increase in 4 metastases. At 12-mo follow-up, 19 metastases increased significantly in size(up to 41% of the initial volume). Volume tumor reduction was correlated to histopathologic subtype.CONCLUSION SRS provided an effective local brain metastases volume control that was demonstrated at follow-up MR imaging. | Gianvincenzo Sparacia Francesco Agnello Aurelia Banco Francesco Bencivinni Andrea Anastasi Giovanna Giordano Adele Taibbi Massimo Galia Tommaso Vincenzo Bartolotta | 2016 | World Journal of Radiology2016，8，12： | 2 |
| 6 | Breathless cancer cells get fat on glutamine显示文摘 | Dimitrios Anastasiou Lewis C Cantley | 2012 | Cell Research2012，22，3： | 2 |
| 7 | Energy conservation in wireless sensor networks: A survey显示文摘 | Giuseppe Anastasi Marco Conti Mario Di Francesco Andrea Passarella | 2008 | Ad Hoc Networks2008，，3： | 2 |
| 8 | Hepatocytegrowth factor stimulates cell mortility in cultures of the striatal progenitor cells ST14A显示文摘 | Salani M Anastasi S | 2003 | J Neurosci Res2003，74，5： | 1 |
| 9 | Economical random wave propagation modelling taking into account non-linear amplitude dispersion 显示文摘 | Zhao Y Anastasiou K | 1993 | Coastal Engineering1993，，20： | 1 |
| 10 | Future CH4 emissions from rice production显示文摘 | Anastasi C Dowding M Simpson V J | 1992 | Journal of Geophysical Research1992，97，： | 1 |
| 11 | Nausea and vomiting in HIV/AIDS显示文摘 | Anastasi JK Capili B | 2011 | Gastroenterol Nuts2011，34，1： | 1 |
| 12 | HE4 in the differential diagnosis of a pelvic mass: a case report 显示文摘 | Anastasi E Granato T Coppa A | 2011 | Int J Mol Sci2011，12，1： | 1 |
| 13 | HIPERLAN/1 MAC Protocol: Stability and Performance Analysis显示文摘 | Anastasi G Lenzini L | 2000 | IEEE Journal on Selected Areas in Communications2000，18，9： | 1 |
| 14 | Water physiology:essentiality,metabolism,and health implications显示文摘 | KAVOURAS S A ANASTASIOU C A | 2010 | Nutr Today2010，45，6： | 1 |
| 15 | Isolation and structure of bombesin and alytesin, two analogous active peptides from the skin of the European amphibians Bombina and Alytes显示文摘 | Anastasi A Erspamer V Bucci M | 1971 | Experi- entia1971，27，2： | 1 |
| 16 | Amiodarone concentration in human myocardium after rapid intravenous-administration显示文摘 | Anastasiou Nana-Mi Nanas JN Alexopoulos G | 1999 | Cardiovascular Drug and thereapy1999，13，： | 1 |
| 17 | Biliary sluage ultrasonic appearance simulating neeplasm显示文摘 | Sutherland GR | 1981 | Br J Radiol1981，94，1： | 1 |
| 18 | Energy conservation in wireless sensor networks: A survey 显示文摘 | Anastasi G Conti M | 2009 | Ad Hoe Networks2009，7，3： | 1 |
| 19 | The use of HE4, CA125 and CA72-4 biomarkers for differential diagnosis between ovarian endometrioma and epithelial ovarian cancer 显示文摘 | Anastasi E Granato T Falzarano R | 2013 | J Ovarian Res2013，6，1： | 1 |
| 20 | The use of HE4, CA125 and CA72-4 biomarkers for dif- ferential diagnosis between ovarian endometrioma and epithe- lial ovarian cancer显示文摘 | Emanuela Anastasi Teresa Granato Renato Falzarano | 2013 | J Ovarian Res2013，5，4： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员