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1Efficacy and safety of tenofovir disoproxil fumarate in pregnancy for the prevention of vertical transmission of HBV infection显示文摘AIM:To evaluate the effects of tenofovir disoproxil fumarate(TDF)use during late pregnancy to reduce hepatitis B virus(HBV)transmission in highly viremic mothers.METHODS:This retrospective study included 45 pregnant patients with hepatitis B e antigen(+)chronic hepatitis B and HBV DNA levels>107copies/mL who received TDF 300 mg/d from week 18 to 27 of gestation(n=21).Untreated pregnant patients served as controls(n =24).All infants received 200 IU of hepatitis B immune globulin(HBIG)within 24 h postpartum and 20μg of recombinant HBV vaccine at 4,8,and 24 wk.Perinatal transmission rate was determined by hepatitis B surface antigen and HBV DNA results in infants at week 28.RESULTS:At week 28,none of the infants of TDFtreated mothers had immunoprophylaxis failure,whereas2(8.3%)of the infants of control mothers had immunoprophylaxis failure(P=0.022).There were no differences between the groups in terms of adverse events in mothers or congenital deformities,gestational age,height,or weight in infants.At postpartum week 28,significantly more TDF-treated mothers had levels of HBV DNA<250 copies/mL and normalized alanine aminotransferase compared with controls(62%vs none,P<0.001;82%vs 61%,P=0.012,respectively).CONCLUSION:TDF therapy during the second or third trimester reduced perinatal transmission rates of HBV and no adverse events were observed in mothers or infants.Mustafa Kemal Celen Duygu Mert Müzeyyen Ay Tuba Dal Safak Kaya Necmettin Yildirim Serda Gulsun Tunga Barcin Sevgi Kalkanli Mehmet Sinan Dal Celal Ayaz 2013World Journal of Gastroenterology2013,19,48:26
2Clinical probability and risk analysis of patients with suspected pulmonary embolism显示文摘BACKGROUND: Pulmonary embolism(PE) is one of the most frequent diseases that could be missed in overcrowded emergency departments as in Turkey. Early and accurate diagnosis could decrease the mortality rate and this standard algorithm should be defi ned. This study is to fi nd the accurate, fast, non-invasive, cost-effective, easy-to-access diagnostic tests, clinical scoring systems and the patients who should be tested for clinical diagnosis of PE in emergency department.METHODS: One hundred and forty patients admitted to the emergency department with the fi nal diagnosis of PE regarding to anamnesis, physical examination and risk factors, were included in this prospective, cross-sectional study. The patients with a diagnosis of pulmonary embolism, acute coronary syndrome or infection and chronic obstructive pulmonary disease(COPD) were excluded from the study. The demographics, risk factors, radiological fi ndings, vital signs, symptoms, physicallaboratory fi ndings, diagnostic tests and clinical scoring systems of patients(Wells and Geneva) were noted. The diagnostic criteria for pulmonary emboli were: fi lling defect in the pulmonary artery lumen on spiral computed tomographic angiography and perfusion defect on perfusion scintigraphy.RESULTS: Totally, 90(64%) of the patients had PE. Age, hypotension, having deep vein thrombosis were the risk factors, and oxygen saturation, shock index, BNP, troponin and fi brinogen levels as for the biochemical parameters were signifi cantly different between the PE(+) and PE(–) groups(P<0.05).The Wells scoring system was more successful than the other scoring systems.CONCLUSION: Biochemical parameters, clinical findings, and scoring systems, when used altogether, can contribute to the diagnosis of PE.Gulden Ozeren Yetgin Sule Akkose Aydin Ozlem Koksal Fatma Ozdemir Dilek Kostak Mert Gokhan Torun 2014World Journal of Emergency Medicine2014,5,4:20
3Tumors of the spine显示文摘Spine tumors comprise a small percentage of reasons for back pain and other symptoms originating in the spine.The majority of the tumors involving the spinal column are metastases of visceral organ cancers which are mostly seen in older patients.Primary musculoskeletal system sarcomas involving the spinal column are rare.Benign tumors and tumor-like lesions of the musculoskeletal system are mostly seen in young patients and often cause instability and canal compromise.Optimal diagnosis and treatment of spine tumors require a multidisciplinary approach and thorough knowledge of both spine surgery and musculoskeletal tumor surgery.Either primary or metastatic tumors involving the spine are demanding problems in terms of diagnosis and treatment.Spinal instability and neurological compromise are the main and critical problems in patients with tumors of the spinal column.In the past,only a few treatment options aiming short-term control were available for treatment of primary and metastatic spine tumors.Spine surgeons adapted their approach for spine tumors according to orthopaedic oncologic principles in the last 20 years.Advances in imaging,surgical techniques and implant technology resulted in better diagnosis and surgical treatment options,especially for primary tumors.Also,modern chemotherapy drugs and regimens with new radiotherapy and radiosurgery options caused moderate to long-term local and systemic control for even primary sarcomas involving the spinal column.Mert Ciftdemir Murat Kaya Esref Selcuk Erol Yalniz 2016World Journal of Orthopedics2016,7,2:13
4二维、三维超声技术检测正常胎儿胸腺的研究显示文摘目的 建立胎儿胸腺二维各径线和三维体积的正常值,并比较胎儿胸腺的二维、三维超声测量.方法 采集567例正常胎儿胸腺的二维超声测值,包括最大横径、前后径、上下径、最大横截面积及三维超声体积.结果 567例胎儿中541例胎儿满意获得胎儿胸腺的最大横径、前后径、上下径和最大横截面积和体积.胎儿胸腺二维各径线、三维体积均随孕周的增加而增加,与孕周均呈直线相关,三维体积与孕周的相关性明显高于二维超声测值(P<0.05).结论 本研究建立了胎儿胸腺二维超声面积、周长、直径、横径和三维超声体积的正常参考值.三维超声测量胎儿胸腺体积与孕周相关性更高,提示较二维超声测量更为准确.李凌 周启昌 邹琳 蒲大荣 章鸣 Joshua Copel Mert Bahtiyar 2011中华超声影像学杂志2011,20,1:7
5Intraoperative acidosis is a new predictor for postoperative pancreatic fistula after pancreaticoduodenectomy显示文摘BACKGROUND:Early diagnosis of postoperative pancreatic fistula(POPF) is important for proper interventions.The preoperative,intraoperative and early postoperative biochemical markers have predictive value of POPF.The present study was to evaluate several simple biochemical parameters in the prediction of POPF.METHODS:Patients who underwent pancreaticoduodenectomy in our center between 2006 and 2015 were reviewed retrospectively.Preoperative and early postoperative biochemical parameters were evaluated.Additionally,the relationship between POPF and p H and lactate level at the end of surgery were analyzed,and neutrophil-to-lymphocyte ratio(NLR),plateletto-lymphocyte ratio(PLR),and red cell distribution widthto-platelet ratio(RPR) were calculated for postoperative days(PODs) 1 and 3.Diagnosis and grading of POPF were performed according to the standards of the International Study Group on Pancreatic Fistula.The patients were divided into two groups:Group 1 with no fistula or grade-A fistula; group 2 with grade-B or-C fistula.These simple biochemical markers were then compared between the two groups.RESULTS:Serum amylase level was significantly higher at POD3,and p H level was significantly lower at the end of operation in group 2 compared with those in group 1.However,the serum amylase was below the upper limit of normal serum level and therefore,the difference was not significant in clinical practice.Receiver operating charecteristic curve analysis showed that p H level was a reliable predictor of POPF(area under the curve:0.713; 95% CI:0.573-0.853).CONCLUSIONS:A low p H level at the end of pancreaticoduodenectomy was a risk factor of POPF.NLR,PLR,and RPR had no predictive value of POPF after pancreaticoduodenectomy.Erdem Kinaci Mert Mahsuni Sevinc Abdulkerim Ozakay Savas Bayrak Ekrem Cakar Serkan Sari 2016Hepatobiliary & Pancreatic Diseases International2016,15,3:7
6添加铈对高压压铸AM50镁合金显微组织和力学性能的影响(英文)显示文摘研究添加铈对高压压铸AM50镁合金显微组织和力学性能的影响。结果表明:添加铈能使AM50镁合金晶粒细化,并使其室温和高温力学性能得到显著改善。相对于未添加Ce和添加0.5%Ce(质量分数)的AM50镁合金,添加1%Ce(质量分数)的镁合金的晶粒更细,力学性能更优。Faruk MERT Ahmet ZDEMIR Karl Ulrich KAINER Norbert HORT 2013Transactions of Nonferrous Metals Society of China2013,23,1:7
7Effect of heat treatment on the microstructure and mechanical properties of AZ80M magnesium alloy fabricated by wire arc additive manufacturing显示文摘To maximize the benefits of wire arc additive manufacturing(WAAM)processes,the effect of post-deposition heat treatment on the microstructure and mechanical properties of WAAM AZ80M magnesium(Mg)alloy was investigated.Three different heat treatment procedures(T4,T5 and T6)were performed.According to the results,after T4 heat treatment,the microsegregation of alloying elements was improved with the eutectic structure dissolved.Samples after T5 heat treatment inherited the net-like distribution of secondary phases similar to the as-deposited sample,where the eutectic structure covering the interdendritic regions and theβ-phase precipitated around the eutectic structure.After T6 heat treatment,the tinyβ-phases re-precipitated from the matrix and distributed in inner and outer of the grains.The hardness distribution of the samples went through T4 and T6 heat treatment was more uniform in comparison to that of T5 heat treated samples.The tensile test showed that the T6 heat treatment improved the strength and ductility,and the anisotropy between horizontal and vertical can be eliminated.Moreover,T4 treated samples exhibited highest ductility.Yangyang Guo Gaofeng Quan Mert Celikin Lingbao Ren Yuhang Zhan Lingling Fan Houhong Pan 2022Journal of Magnesium and Alloys2022,10,7:5
8硫酸溶液中1,1′-硫代羰基二咪唑在碳钢上的吸附及缓蚀影响和碘离子的增强效应(英文)显示文摘The inhibition effect of 1,1′-thiocarbonyldiimidazole (TCDI) on the corrosion behaviors of mild steel (MS) in 0.5 mol·L-1 H2SO4 solution was studied with the help of potentiodynamic polarization, electrochemical impedance spectroscopy (EIS), and linear polarization resistance (LPR) techniques. The effect of immersion time on the inhibition effect of TCDI was also investigated over 72 h. For the long-term tests, hydrogen evolution with immersion time (VH2-t) was measured in addition to the three techniques already mentioned. The thermodynamic parameters, such as adsorption equilibrium constant (Kads) and adsorption free energy (△Gads) values, were calculated and discussed. To clarify inhibition mechanism, the synergistic effect of iodide ion was also investigated. The potential of zero charge (PZC) of the MS was studied by electrochemical impedance spectroscopy method, and a mechanism of adsorption process was proposed. It was demonstrated that inhibition efficiency increased with the increase in TCDI concentration and synergistically increased in the presence of KI. The inhibition efficiency was discussed in terms of adsorption of inhibitor molecules on the metal surface and protective film formation.SOLMAZ R MERT M. E KARDA■ G YAZICI B ERBL M 2008物理化学学报2008,24,7:4
9Hepatic cystic echinococcosis:Percutaneous treatment as an outpatient procedure显示文摘Objective:To demonstrate utility and safety of the puncture aspiration injection and reospiration(PAIR)technique for outpatients.Methods:Percutaneous treatment with US guidance was applied to 33 patients for 44 cysts.Patients treated with the PAIR technique,were outpatients.PAIR and catheterization technique were evaluated for efficacy and safety of procedure and complication rates.Results:Thirty-five of 44 cysts were treated with the PAIR and 9 of 44 were treated with the catheterization technique.The success rate of the cysts Gharbi type 1(CEI)and type 2(Ct3a)treated with the PAIR technique was 1009.hi the follow up of 9 cysts treated with the catheterization technique,2 of them(22%)developed cyst infection and 1(11%)developed a biliary fistula.Conclusions:The PAIR technique was found to be an effective and safe approach in order to treat Gharbi type 1 and type 2 cysts percutaneously for outpatients.It has a very low complication rate in comparison with the catheterization technique.So every effort should be mode to finish the treatment with PAIR technique.Mert Kroglu Bekir Erol Cemil Gürses Baris Türkbey Cem Yunus Bas Ahmet Sükrü Alparslan Banu Kale Kroglu Iclal Erdem Toslak Bülent eki Okan Akhan 2014Asian Pacific Journal of Tropical Medicine2014,7,3:4
10The Neurotrophic Factor Artemin Promotes Pancreatic Cancer Invasion显示文摘Güralp O. Ceyhan Nathalia A. Giese Mert Erkan Annika G. Kerscher Moritz N. Wente Thomas Giese Markus W. Büchler Helmut Friess 2006Annals of Surgery2006,,2:3
11超音速火焰喷涂与激光重熔Al_(0.2)CrFeNi(Co,Cu)合金的干滑动磨损及氧化性能对比研究显示文摘用超音速火焰喷涂(HVOF)法在316L不锈钢基体上沉积Al_(0.2)CrFeNiCo和Al_(0.2)CrFeNiCu两种高熵合金涂层,然后对涂层进行激光重熔(LR)以改善其显微组织。研究LR工艺对涂层干滑动磨损和氧化行为的影响。结果表明,将粉末与单体元素混合导致HVOF涂层中形成内氧化物。LR消除了氧化物和气孔。LR后,两种合金中均以FCC相为主,而在Al_(0.2)CrFeNiCo合金中观察到BCC、sigma和Cr2O3相。HVOF后,Al_(0.2)CrFeNiCo和Al_(0.2)CrFeNiCu涂层的硬度分别为HV 591和HV 361。LR后,其硬度分别减小到HV 259和HV 270。与其他样品相比,虽然HVOF涂层受载荷增加的影响最大,但其表现出最高的耐磨性,且基体的耐磨性最差。氧化实验后,HVOF涂层被完全氧化,氧化50h后涂层因其多孔结构从基体上脱落。LR涂层具有较好的抗氧化性能。氧化实验后,Al_(0.2)CrFeNiCo涂层主要由Cr2O3氧化层组成,Cr2O3氧化层在氧化实验后期的生长速度较慢,而Al_(0.2)CrFeNiCu涂层则主要由尖晶石相组成。Azmi ERDOGAN Kadir Mert DOLEKER 2021Transactions of Nonferrous Metals Society of China2021,31,8:3
12Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid显示文摘Addiction to synthetic cannabinoids(SCs) is a growing social and health problem worldwide. Chronic use of SCs may cause adverse effects in the gastrointestinal system. We describe a very rare case of acute gastric dilatation(AGD) and hepatic portal venous gas(HPVG),with findings of acute abdomen resulting from chronic use of a SC, Bonzai. AGD and HPVG were detected by computerized tomography examination. Patchy mucosal ischemia was seen in endoscopic examination. Despite the findings of an acute abdomen, a non-surgical approach with nasogastric decompression, antibiotic therapy, and close radiologic and endoscopic followup was preferred in the presented case. Clinical and radiologic findings decreased dramatically on the first day, and endoscopic findings gradually disappeared over 7 d. In conclusion, this case shows that chronic use of a SC may cause AGD and accompanying HPVG,which can be managed non-surgically despite the findings of acute abdomen.Mert Mahsuni Sevinc Erdem Kinaci Savas Bayrak Aytul Hande Yardimci Ekrem Cakar Hasan Bektas 2015World Journal of Gastroenterology2015,21,37:3
13Nerve Growth Factor and Artemin Are Paracrine Mediators of Pancreatic Neuropathy in Pancreatic Adenocarcinoma显示文摘Güralp O. Ceyhan Karl-Herbert Sch?fer Annika G. Kerscher Ulrich Rauch Ihsan Ekin Demir Mustafa Kadihasanoglu Carolin B?hm Michael W. Müller Markus W. Büchler Nathalia A. Giese Mert Erkan Helmut Friess 2010Annals of Surgery2010,,5:2
14Retrograde Intrarenal Surgery for the Treatment of Renal Stones in Patients With a Solitary Kidney显示文摘Gokhan Atis Cenk Gurbuz Ozgur Arikan Mert Kilic Sabri Pelit Cengiz Canakci Samet Gungor Turhan Caskurlu 2013Urology2013,,:2
15Strong strain path dependence of strain localizations and fracture in magnesium AZ31 sheet显示文摘This study compares the deformation and fracture behavior of a basal-textured Mg AZ31 alloy sheet under uniaxial tension and biaxial stretching by using an in-plane biaxial test setup capable of observing and measuring the deformation at both meso(millimeter)and microstructure scales.Strain distributions at the mesoscale and accompanying fracture surfaces indicate a significant dependence on strain path.At the microscale,limited slip activity in biaxial case promotes contraction twins,where severe strain localizations(εmax/εmean≈220)to the twins and their boundaries cause mainly transgranular fracture.This leads to a brittle,and a more pronounced shear-type fracture under biaxial stretching.In uniaxial case,considerable tensile twinning activity reorients the initial texture for slip activity.Strain localizations(εmax/εmean≈2)to the grain interiors and boundaries initiate mainly intergranular fracture.Samples fail by displaying both brittle and ductile fracture structures,with smaller shear lips compared to the biaxial case.Kivanc Alkan O.Berk Aytuna Baran Guler Mert Efe 2020Journal of Magnesium and Alloys2020,8,2:2
16Classification of Percutaneous Nephrolithotomy Complications Using the Modified Clavien Grading System: Looking for a Standard显示文摘Ahmet Tefekli Mert Ali Karadag Kadir Tepeler Erhan Sari Yalcin Berberoglu Murat Baykal Omer Sarilar Ahmet Yaser Muslumanoglu 2007European Urology2007,,1:2
17A Computational Investigation of the Thermohydraulics of an EGS Project显示文摘A numerical analysis of the thermohydraulics of an enhanced geothermal system project is presented. The rock structures are modelled as porous medium, based on the computationally obtained hydraulic fracturing data of other authors. The influence of the domain size, grid resolution, temporal resolution and the discretization scheme is assessed to obtain a highly accurate numerical solution under the prevailing modelling assumptions. Based on the numerical model, different production scenarios are investigated and discussed. The relative positioning of the injection and production ports is also analyzed. It is shown that there is a considerable potential for optimizing the production rate and the port configuration to obtain the most favorable results for the production temperature, investment costs and operation costs.BENIM Ali Cemal CICEK Aydin EKER Arif Mert 2018Journal of Thermal Science2018,27,5:2
18Ultra-fast freezing and low storage temperatures are not necessary to maintain the functional properties of manufacturing beef显示文摘M.M. Farouk K.J. Wieliczko I. Merts 2003Meat Science2003,,1:2
19Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma显示文摘Mert Erkan Carolin Reiser-Erkan Christoph W. Michalski Stefanie Deucker Danguole Sauliunaite Sylvia Streit Irene Esposito Helmut Friess J?rg Kleeff 2009Neoplasia2009,,:2
20Critical evaluation of the role of acarbose in the treatment of diabetes: patient considerations显示文摘Christoph Rosak Mertes 2012Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy . 2012 (defa)2012,,:2
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