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| 1 | Impact of obesity on the surgical outcome following repeat hepatic resection in Japanese patients with recurrent hepatocellular carcinoma显示文摘AIM: To evaluate the impact of obesity on the posto- perative outcome after hepatic resection in patients with hepatocellular carcinoma (HCC). METHODS: Data from 328 consecutive patients with primary HCC and 60 patients with recurrent HCC were studied. We compared the surgical outcomes between the non-obese group (body mass index: BMI < 25 kg/m2) and the obese group (BMI ≥ 25 kg/m2). RESULTS: Following curative hepatectomy in patients with primary HCC, the incidence of postoperative complications and the long-term prognosis in the non- obese group (n = 240) were comparable to those in the obese group (n = 88). Among patients with recurrent HCC, the incidence of postoperative complications after repeat hepatectomy was not significantly different between the non-obese group (n = 44) and the obese group (n = 16). However, patients in the obese group showed a significantly poorer long-term prognosis than those in the non-obese group (P < 0.05, five-yearsurvival rate; 51.9% and 92.0%, respectively). CONCLUSION: Obesity alone may not have an adverse effect on the surgical outcomes of patients with primary HCC. However, greater caution seems to be required when planning a repeat hepatectomy for obese patients with recurrent HCC. | Tohru Utsunomiya Masahiro Okamoto Toshihumi Kameyama Ayumi Matsuyama Manabu Yamamoto Megumu Fujiwara Masaki Mori Shiomi Aimitsu Teruyoshi Ishida | 2008 | World Journal of Gastroenterology2008，14，10： | 10 |
| 2 | Prognostic Impact of Anatomic Resection for Hepatocellular Carcinoma显示文摘 | Kiyoshi Hasegawa Norihiro Kokudo Hiroshi Imamura Yutaka Matsuyama Taku Aoki Masami Minagawa Keiji Sano Yasuhiko Sugawara Tadatoshi Takayama Masatoshi Makuuchi | 2005 | Annals of Surgery2005，，2： | 6 |
| 3 | Gastric adenocarcinoma of fundic gland type spreading to heterotopic gastric glands显示文摘Herein, we present a case of gastric adenocarcinoma of fundic gland type(GA-FG) spreading to heterotopic gastric glands(HGG) in the submucosa. A 58-year-old man with epigastric pain was referred to our hospital and underwent an esophagogastroduodenoscopy. A Borrmann type II gastric cancer at the antrum and a 10 mm submucosal tumor-like lesion in the lesser curvature of the upper third of the stomach were detected. Histological examination of the biopsy specimens obtained from the submucosal tumorlike lesion suggested a GA-FG. Therefore, endoscopic submucosal dissection was performed as excisional biopsy, and histopathological examination of the resected specimen confirmed a GA-FG and HGG proximal to the GA-FG. Although the GA-FG invaded the submucosal layer slightly, the submucosal lesion of the GA-FG had a poor stromal reaction and was located just above the HGG in the submucosa. Therefore, wefinally diagnosed the lesion as a GA-FG invading the submucosal layer by spreading to HGG. | Shigeo Manabe Ken-ichi Mukaisho Takayuki Yasuoka Fumitaka Usui Tatsuzo Matsuyama Ikuhiro Hirata Yoshio Boku Shuji Takahashi | 2017 | World Journal of Gastroenterology2017，23，38： | 6 |
| 4 | AFP, AFP-L3, DCP, and GP73 as markers for monitoring treatment response and recurrence and as surrogate markers of clinicopathological variables of HCC显示文摘 | Kentaroh Yamamoto Hiroshi Imamura Yutaka Matsuyama Yukio Kume Hitoshi Ikeda Gary L. Norman Zakera Shums Taku Aoki Kiyoshi Hasegawa Yoshifumi Beck Yasuhiko Sugawara Norihiro Kokudo | 2010 | Journal of Gastroenterology2010，，12： | 6 |
| 5 | Prospective Cohort Study of Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma in 8510 Patients显示文摘 | Kenichi Takayasu Shigeki Arii Iwao Ikai Masao Omata Kiwamu Okita Takafumi Ichida Yutaka Matsuyama Yasuni Nakanuma Masamichi Kojiro Masatoshi Makuuchi Yoshio Yamaoka | 2006 | Gastroenterology2006，，2： | 5 |
| 6 | Ultrasound-guided vs endoscopic ultrasound-guided fine-needle aspiration for pancreatic cancer diagnosis显示文摘AIM: To clarify the effectiveness and safety of endo- scopic ultrasound-guided fine-needle aspiration (EUS-FNA) for the diagnosis of pancreatic cancer (PC). METHODS: Patients who were diagnosed with unresectable, locally advanced or metastatic PC between February 2006 and September 2011 were selected for this retrospective study. FNA biopsy for pancreatic tumors had been performed percutaneously under extracorporeal ultrasound guidance until October 2009; then, beginning in November 2009, EUS-FNA has been performed. We reviewed the complete medical records of all patients who met the selection criteria for the following data: sex, age, location and size of the targeted tumor, histological and/or cytological findings, details of puncture procedures, time from day of puncture until day of definitive diagnosis, and details of severe adverse events. RESULTS: Of the 121 patients who met the selection criteria, 46 had a percutaneous biopsy (Group A) and 75 had an EUS-FNA biopsy (Group B). Adequate cytological specimens were obtained in 42 Group A patients (91.3%) and all 75 Group B patients (P=0.0192), and histological specimens were obtained in 41 Group A patients (89.1%) and 65 Group B patients (86.7%). Diagnosis of malignancy by cytology was positive in 33 Group A patients (78.6%) and 72 Group B patients (94.6%) (P=0.0079). Malignancy by both cytology and pathology was found in 43 Group A (93.5%) and 73 Group B (97.3%) patients. The mean period from the puncture until the cytological diagnosis in Group B was 1.7 d, which was significantly shorter than that in Group A (4.1 d) (P < 0.0001). Severe adverse events were experienced in two Group A patients (4.3%) and in one Group B patient (1.3%). CONCLUSION: EUS-FNA, as well as percutaneous needle aspiration, is an effective modality to obtain cytopathological confirmation in patients with advanced PC. | Masato Matsuyama Hiroshi Ishii Kensuke Kuraoka Seigo Yukisawa Akiyoshi Kasuga Masato Ozaka Sho Suzuki Kouichi Takano Yuko Sugiyama Takao Itoi | 2013 | World Journal of Gastroenterology2013，19，15： | 5 |
| 7 | Endoscopic tissue shielding method with polyglycolic acid sheets and fibrin glue to prevent delayed perforation after duodenal endoscopic submucosal dissection显示文摘 | Kengo Takimoto Yoshihito Imai Kiichi Matsuyama | 2014 | Digestive Endoscopy2014，，： | 5 |
| 8 | 机器人辅助与传统腹腔镜低位前切除术治疗直肠癌的疗效比较:日本国家临床数据库的倾向性匹配研究显示文摘目的:机器人辅助腹腔镜手术与传统腹腔镜手术相比有一些优势。但基于人群的直肠癌低位前切除术的比较研究有限。本研究旨在比较机器人辅助腹腔镜低位前切除术(RALAR)和传统腹腔镜手术的围手术期结果。方法:采用回顾性队列研究的方法,分析日本国家临床数据库中2018年10月至2019年12月期间接受RALAR或传统腹腔镜低位前切除术(CLLAR)治疗的直肠癌患者的临床数据。 | 池诏丞 MATSUYAMA T ENDO H YAMAMOTO H | 2021 | 结直肠肛门外科2021，27，6： | 5 |
| 9 | Peeling a giant ileal lipoma with endoscopic unroofing and submucosal dissection显示文摘Lipoma is relatively common in the colon but is less often in the small intestine. Most lipomas are incidentally detected at endoscopy and are usually small and asymptomatic. However, some of them can present with obstruction and/or intussusceptions. Surgical resection is commonly recommended to remove such significant lipomas with a limited pedicle and larger than 2 cm in size, as endoscopic resection may result in unfavorable complications such as intestinal perforations. We report a case of 62-year-old man presenting with hematochezia. Colonoscopy showed a submucosal tumor, about 50 mm in size, in the terminal ileum. A clinical diagnosis of lipoma was established based on the findings of colonoscopy and abdominal computed tomography (CT). As the patient complained of hematochezia and mild iron deficiency anemia associated with repeated tumor prolapse, we decided to remove his lipoma. Consequently, the lesion was completely removed en bloc . Although abdominal CT immediately after removal of the lesion showed a small amount of free air, conservative treatment was successfully carried out for the perforation. Histologically, the removed lesion was a lipoma. | Takashi Morimoto Kuang-I Fu Hironori Konuma Yuko Izumi Syujirou Matsuyama Kanako Ogura Akihisa Miyazaki Sumio Watanabe | 2010 | World Journal of Gastroenterology2010，16，13： | 4 |
| 10 | Arthroscopic approach to the posterior compartment of the knee using a posterior transseptal portal显示文摘Arthroscopic surgery of the posterior compartment ofthe knee is difficult when only two anterior portals are used for access because of the inaccessibility of the back of the knee. Since its introduction, the posterior transseptal portal has been widely employed to access lesions in the posterior compartment. However, special care should be taken to avoid neurovascular injuries around the posteromedial, posterolateral, and transseptal portals. Most importantly, popliteal vessel injury should be avoided when creating and using the transseptal portal during surgery. Purpose of the present study is to describe how to avoid the neurovascular injuries during establishing the posterior three portals and to introduce our safer technique to create the transseptal portal. To date, we have performed arthroscopic surgeries via the transseptal portal in the posterior compartments of 161 knees and have not encountered nerve or vascular injury. In our procedure, the posterior septum is perforated with a 1.5-3.0-mm Kirschner wire that is protected by a sheath inserted from the posterolateral portal and monitored from the posteromedial portal to avoid popliteal vessel injury. | Tsuyoshi Ohishi Masaaki Takahashi Daisuke Suzuki Yukihiro Matsuyama | 2015 | World Journal of Orthopedics2015，6，7： | 4 |
| 11 | 脑缺血后N-myc下游调控基因2保护血脑屏障完整性显示文摘脑缺血后血脑屏障(BBB)的破坏与外周细胞向脑内浸润、病孔损形成与进展、以及临床病程恶化密切相关。目前BBB完整性的调控机制,尤其是在永久性缺血后的调控机制尚未明确。本研究使用小鼠永久性脑缺血模型进行相关研究,结果显示,星形胶质细胞N-myc下游调控基因2(NDRG2)可能是缺血性脑卒中后BBB通透性的调控分子,该分子与分化和应激相关。免疫组化显示,在永久性大脑中动脉闭塞(MCAO)后,NDRG2在星形胶质细胞中的表达显著增加。敲除NDRG2基因,脑梗死体积增加,免疫细胞在缺血同侧大脑半球积聚增加。MCAO后,NDRG2基因敲除小鼠缺血侧皮质的缺血灶内及灶周血管周围区域内的血清蛋白(包括纤维蛋白原和免疫球蛋白)的外渗增强此之,MCAO后NDRG2基因敲除小鼠体内基质金属蛋白酶(MMPs)的表达也显著增加。在细胞培养中,NDRG2-/-星形胶质细胞中MMP-3的表达和分泌增加,这种增加可被腺病毒介导的NDRG2再表达所逆转。综上所述,脑缺血后,星形胶质细胞内的NDRG2可能通过调节MMP的表达,而在BBB通透性的调节和免疫细胞浸润中起到重要作用。 | Takarada-Iemata M Yoshikawa A Ta HM Okitani N Nishiuchi T Aida Y Kamide T Hattori T Ishii H Tamatani T Le TM Roboon J Kitao Y Matsuyama T Nakada M Hori O 聂昊 | 2018 | 神经损伤与功能重建2018，13，4： | 4 |
| 12 | WAVE TRANSMISSION AND REFIECTION DUE TO A THIN VERTICAL BARRIER显示文摘WT5”BZ]A numerical method, the boundary fitted coordinate method (BFC), was used to investigate the transmission and reflection of water waves due to a rigid thin vertical barrier descending from the water surface to a depth, i.e., a curtain-wall type breakwater. A comparison between the present computed results and previous experimental and analytical results was carried out which verifies the prediction of the BFC method. Wave transmission and reflection due to the barrier were computed, and the transmission and refiection coefficients were given in a figure. [WT5”HZ] | Gao Xue-ping Hydraulics Institute, School of Civil Engineering, Tianjin University, Tianjin300072, China Nakamura Takayuki , Inouchi Kunimitsu Ehime University, Matsuyama 790-8577, Japan Kakinuma Tadao Nagasaki Comprehensive University, Nagasaki | 2001 | Journal of Hydrodynamics2001，13，1： | 4 |
| 13 | COMPARISON OF SCOURS IN FRONT OF VERTICAL BREAKWATERS DUE TO REGULAR AND IRREGULAR WAVES显示文摘In this paper the scours of sand bed due to regular and irregular waves in front of vertical breakwaters, such as scouring patterns, scouring mechanisms, etc., are investigated. Thereby, the scours under the action of the two kinds of waves are compared connected. | Gao Xue ping Department of Civil and Environmental Engineering, Faculty of Engineering, Ehime University, 3 Bunkyo cho, Matsuyama 790 77, JapanKunimitsu Inouchi Center for Cooperative Research and Development, Ehime University, 3 Bunkyo cho, Mats | 2000 | Journal of Hydrodynamics2000，12，1： | 3 |
| 14 | Practical studies on rockfall simulation by DDA显示文摘In this paper,simulations of real rockfall by discontinuous deformation analysis (DDA) are conducted.In the simulations,the energy losses of rockfall are categorized into three types,i.e.the loss by friction,the loss by collision,and the loss by vegetation.Modeling of the energy loss using absolute parameters is conducted by the DDA method.Moreover,in order to verify the applicability and validity of the proposed DDA,field tests on rockfall and corresponding simulations of rockfall tests by DDA are performed.The simulated results of rockfall velocity and rockfall jumping height agree well with those obtained from the field tests.Therefore,the new technique properly considers the energy-absorption ability of slope based on vegetation condition and shape of the rockfall,and provides a new method for the assessment and preventive design of rockfall. | Hiroyuki Matsuyama Satoshi Nishiyama Yuzo Ohnishi | 2011 | Journal of Rock Mechanics and Geotechnical Engineering2011，3，1： | 3 |
| 15 | Effect of Percolation Pattern on Yields and Accumulation of Copper and Cadmium in the Rice Plants with Soil Dressing Models显示文摘 | S.K. Paul C. Sasaki N. Matsuyama K. Kato | 2011 | Journal of Environmental Science and Engineering2011，5，11： | 3 |
| 16 | Effect of spinal cord preconditioning on paraplegia during cross-clamping of the thoracic aorta显示文摘 | Matsuyama K Chiba Y Ihaya A Kimura T Tanigawa N Muraoka R | 1997 | Ann Thorac Surg1997，63，5： | 2 |
| 17 | Adipocyte-Derived Plasma Protein, Adiponectin, Suppresses Lipid Accumulation and Class A Scavenger Receptor Expression in Human Monocyte-Derived Macrophages显示文摘 | Noriyuki Ouchi Shinji Kihara Yukio Arita Makoto Nishida Akifumi Matsuyama Yoshihisa Okamoto Masato Ishigami Hiroshi Kuriyama Ken Kishida Hitoshi Nishizawa Kikuko Hotta Masahiro Muraguchi Yasukazu Ohmoto Shizuya Yamashita Tohru Funahashi Yuji Matsuzawa | 2001 | Circulation: Journal of the American Heart Association2001，，8： | 2 |
| 18 | Evidence‐based C linical P ractice G uidelines for H epatocellular C arcinoma: The J apan S ociety of H epatology 2013 update (3rd JSH‐HCC G uidelines)显示文摘 | Norihiro Kokudo Kiyoshi Hasegawa Masaaki Akahane Hiroshi Igaki Namiki Izumi Takafumi Ichida Shinji Uemoto Shuichi Kaneko Seiji Kawasaki Yonson Ku Masatoshi Kudo Shoji Kubo Tadatoshi Takayama Ryosuke Tateishi Takashi Fukuda Osamu Matsui Yutaka Matsuyama Ta | 2015 | Hepatol Res2015，，2： | 2 |
| 19 | 肝门部胆管癌手术治疗中血管(特别是肝动脉)切除重建的意义显示文摘方法:回顾性收集从1992年4月到2014年3月横滨市立大学医学院附属医院172例肝门部胆管癌手术病人的影像学资料、手术及预后相关资料。将手术病人是否血管重建分成三组:1.VR(-)组:门静脉、肝动脉都未进行切除(74例)。2.VR-(PV)组:只对门静脉切除重建组(54例)。 | Ryusei Matsuyama Ryutaro Mori Yohei Ota 林杰 刘付宝 | 2016 | 肝胆外科杂志2016，24，5： | 2 |
| 20 | Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy显示文摘 | Imamura H Matsuyama Y Tanaka E | 2003 | Journal of Hepatology2003，，02： | 2 |
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