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| 1 | 机器人辅助与传统腹腔镜低位前切除术治疗直肠癌的疗效比较:日本国家临床数据库的倾向性匹配研究显示文摘目的:机器人辅助腹腔镜手术与传统腹腔镜手术相比有一些优势。但基于人群的直肠癌低位前切除术的比较研究有限。本研究旨在比较机器人辅助腹腔镜低位前切除术(RALAR)和传统腹腔镜手术的围手术期结果。方法:采用回顾性队列研究的方法,分析日本国家临床数据库中2018年10月至2019年12月期间接受RALAR或传统腹腔镜低位前切除术(CLLAR)治疗的直肠癌患者的临床数据。 | 池诏丞 MATSUYAMA T ENDO H YAMAMOTO H | 2021 | 结直肠肛门外科2021，27，6： | 5 |
| 2 | 脑缺血后N-myc下游调控基因2保护血脑屏障完整性显示文摘脑缺血后血脑屏障(BBB)的破坏与外周细胞向脑内浸润、病孔损形成与进展、以及临床病程恶化密切相关。目前BBB完整性的调控机制,尤其是在永久性缺血后的调控机制尚未明确。本研究使用小鼠永久性脑缺血模型进行相关研究,结果显示,星形胶质细胞N-myc下游调控基因2(NDRG2)可能是缺血性脑卒中后BBB通透性的调控分子,该分子与分化和应激相关。免疫组化显示,在永久性大脑中动脉闭塞(MCAO)后,NDRG2在星形胶质细胞中的表达显著增加。敲除NDRG2基因,脑梗死体积增加,免疫细胞在缺血同侧大脑半球积聚增加。MCAO后,NDRG2基因敲除小鼠缺血侧皮质的缺血灶内及灶周血管周围区域内的血清蛋白(包括纤维蛋白原和免疫球蛋白)的外渗增强此之,MCAO后NDRG2基因敲除小鼠体内基质金属蛋白酶(MMPs)的表达也显著增加。在细胞培养中,NDRG2-/-星形胶质细胞中MMP-3的表达和分泌增加,这种增加可被腺病毒介导的NDRG2再表达所逆转。综上所述,脑缺血后,星形胶质细胞内的NDRG2可能通过调节MMP的表达,而在BBB通透性的调节和免疫细胞浸润中起到重要作用。 | Takarada-Iemata M Yoshikawa A Ta HM Okitani N Nishiuchi T Aida Y Kamide T Hattori T Ishii H Tamatani T Le TM Roboon J Kitao Y Matsuyama T Nakada M Hori O 聂昊 | 2018 | 神经损伤与功能重建2018，13，4： | 4 |
| 3 | Effect of spinal cord preconditioning on paraplegia during cross-clamping of the thoracic aorta显示文摘 | Matsuyama K Chiba Y Ihaya A Kimura T Tanigawa N Muraoka R | 1997 | Ann Thorac Surg1997，63，5： | 2 |
| 4 | Serum levels of vascular endothelial growth factor dependent on the stage progression of lung cancer显示文摘 | Matsuyama W Hashiguchi T Mizoguchi A | | 0，，04： | 2 |
| 5 | Diverse myocardial extension and autonomic innervation on ligament of Marshall in humans显示文摘 | Makino M Inoue S Matsuyama T A | 2006 | J Cardiovascular Electrophysiology2006，16，7： | 1 |
| 6 | Induction of tumor necrosis factoy-αin the mouse hippocampus following transient forebrain is chemia显示文摘 | Uno H Matsuyama T Akita H | 1997 | J Cereb Blood Flow Metab1997，7，5： | 1 |
| 7 | Facilitate transport of CO2 through polyethylenenimine/poly (vinyl alcohol) blend membrane 显示文摘 | Terada A Nakagawara T | 1999 | J Membr Sci1999，163，2： | 1 |
| 8 | Spermidine synthase genes are essential for survival of Arabidopsis 显示文摘 | IMAI A MATSUYAMA T HANZAWA Y | 2004 | Plant Physiology2004，135，3： | 1 |
| 9 | Brainstem auditory evoked potentials during brainstem ischemia and reperfusion in gerbils显示文摘 | Hata R Matsumoto M Matsuyama T | 1998 | Neuroscience1998，83，1： | 1 |
| 10 | Interactions between the red tide dinoflagellates Heterocapsa circularisquama and Gymnodinium mikinotoi in laboratory culture 显示文摘 | Uchida T Toda S Matsuyama Y | 1999 | Journal of Experimental Marine Biology and Ecology1999，241，： | 1 |
| 11 | High-quality Polycrystalline Silicon Thin Film Prepared by a Solid Phase Crystallization Method显示文摘 | Terada N Matsuyama T Baba T | 1996 | J Non-crystalline Solids1996，，： | 1 |
| 12 | Preparation of polyethylene hollow fiber membrane via thermally induced phase separation显示文摘 | Matsuyama H Okafuji H Maid T | 2003 | J Membr Sci2003，223，： | 1 |
| 13 | Promotion of axonal maturation and prevention of memory loss in mice by extracts of astragalus mongholicus 显示文摘 | Tohda C Tamura T Matsuyama S | 2006 | Br J Pharmacol2006，149，5： | 1 |
| 14 | Kinetics of apoptosis in the lung of mice with allergic airway inflammation 显示文摘 | Kodama T Matsuyama T Miyata S | 1998 | Clin Exp Allergy1998，28，： | 1 |
| 15 | Prevention of infectionin dental procedures显示文摘 | Matsuyama M Usami L Masuda K t al | 2007 | J Hosp infect2007，3，1： | 1 |
| 16 | Expression of hypoxia-inducible faetor-lalpha in esophageal squamous cell carcinoma显示文摘 | Matsuyama T Nakanishi K Hayashi T | 2005 | Cancer Sci2005，96，3： | 1 |
| 17 | Energy decay for the wave equations II:global existence and decay of solutions显示文摘 | MATSUYAMA T IKEHHATA R | | 0，，： | 1 |
| 18 | Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy显示文摘 | Imamura H Matsuyama Y Tanaka E Ohkubo T Hasegawa K Miyagawa S Sugawara Y Minagawa M Takayama T Kawasaki S Makuuchi M | | 0，，02： | 1 |
| 19 | Serum level of vascular endothelial growth factor dependent on the stage progression of lung cancer 显示文摘 | Matsuyama W Hashiguchi T Mizoguchi T | 2000 | Chest2000，118，4： | 1 |
| 20 | Psychobehavioral and immunological characteristics of adult people with chronic fatigue and patients with chronic fatigue syndrome 显示文摘 | Masuda A Nozoe SI Matsuyama T | 1994 | Psychosomatic Medicine1994，56，6： | 1 |
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