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| 1 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 2 | META-R:A software to analyze data from multi-environment plant breeding trials显示文摘META-R(multi-environment trial analysis in R)is a suite of R scripts linked by a graphical user interface(GUI)designed in Java language.The objective of META-R is to accurately analyze multi-environment plant breeding trials(METs)by fitting mixed and fixed linear models from experimental designs such as the randomized complete block design(RCBD)and the alpha-lattice/lattice designs.META-R simultaneously estimates the best linear and unbiased estimators(BLUEs)and the best linear and unbiased predictors(BLUPs).Additionally,it computes the variance-covariance parameters,as well as some statistical and genetic parameters such as the least significant difference(LSD)at 5%significance,the coefficient of variation in percentage(CV),the genetic variance,and the broad-sense heritability.These parameters are very important in the selection of top performing genotypes in plant breeding.META-R also computes the phenotypic and genetic correlations among environments and between traits,as well as their statistical significance.The genetic correlations between environments or traits can be visualized in a biplot graph or a tree diagram(dendrogram).Genetic correlations are very important for identifying environments with similar behavior or making indirect selection and identifying the most highly associated traits.META-R performs multi-environment analyses by using the residual maximum likelihood(REML)method;these analyses can be done by environment,across environments by grouping factors(stress conditions,nitrogen content,etc.)and across environments;the analyses across environments can be done with a pre-defined degree of heritability. | Gregorio Alvarado Francisco M.Rodríguez Angela Pacheco Juan Burgueño JoséCrossa Mateo Vargas Paulino Pérez-Rodríguez Marco A.Lopez-Cruz | 2020 | The Crop Journal2020，8，5： | 4 |
| 3 | Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence显示文摘 | Juan C. Acosta Ana O’Loghlen Ana Banito Maria V. Guijarro Arnaud Augert Selina Raguz Marzia Fumagalli Marco Da Costa Celia Brown Nikolay Popov Yoshihiro Takatsu Jonathan Melamed Fabrizio d’Adda di Fagagna David Bernard Eva Hernando Jesús Gil | 2008 | Cell2008，，6： | 2 |
| 4 | Selective proliferation of normal human melanocytes in vitro in the presence of phorbol easter and cholera toxin显示文摘 | Eisinger M Marco O | 1982 | Proc Natl Acad Sci USA1982，79，： | 1 |
| 5 | The application of electrochemical technology to the remediation of oily wastewater显示文摘 | Marcos R G Santos Marilia O F Goulart Josealdo Tonholo | 2006 | Chemosphere2006，64，3： | 1 |
| 6 | Doehlert matrix for optimisation of procedure for determination of nickel in saline oil-refinery effluents by use of flame atomic absorption spectrometry after preconcentration by cloud-point extraction显示文摘 | Marcos Bezerra André L. B. Concei??o Sérgio L. C. Ferreira | 2004 | Analytical and Bioanalytical Chemistry2004，，3： | 1 |
| 7 | 查看详情显示文摘 | Marco de Lucas M C Fabreguette F Linsavanh M Imhoff L Heintz O Josse-Courty C Mesnier M T Potin V Bourgeois S Sacilotti M | | 0，，： | 1 |
| 8 | Serotonin - induced smooth muscle hyperplasia in various forms of human pulmonary hypertension显示文摘 | Marcos E Fadel E Sanchez O | 2004 | Circ Res2004，94，9： | 1 |
| 9 | Tumor thickness as a predictive factor of lymph node metastasis and disease recurrence in T1N0 and T2N0 squamous cell carcinoma of the oral tongue显示文摘 | Leandro Luongo de Matos Gabriel Manfro Ricardo Vieira dos Santos Elaine Stabenow Evandro Sobroza de Mello Venancio Avancini F. Alves Fábio Roberto Pinto Marco Aurélio Vamondes Kulcsar Lenine Garcia Brand?o Cláudio Roberto Cernea | 2014 | Oral Surgery Oral Medicine Oral Pathology and Oral Radiology2014，，： | 1 |
| 10 | Structural evolution of Eucalyptus tar pitch-based carbons during carbonization显示文摘 | MARCOS J P VANYA M D NELCY D S CHOYU O SATIKA O LUIZ C P | 2005 | Biomass Bioenergy2005，28，1： | 1 |
| 11 | Nontrival solutions for a class of semilinear biharmonie problems involving critical exponents 显示文摘 | Alves C O Joao Marcos do O Miyagaki O H | 2001 | Nonlinear Analysis2001，46，： | 1 |
| 12 | The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens显示文摘 | Daniel H.D. Gray Fiona Kupresanin Stuart P. Berzins Marco J. Herold Lorraine A. O’Reilly Philippe Bouillet Andreas Strasser | 2012 | Immunity2012，，3： | 1 |
| 13 | 显示文摘 | Brukman M J Marco G O Dunbar T D | 2006 | Langmuir2006，22，： | 1 |
| 14 | Host–microbe interactions that facilitate gut colonization by commensal bifidobacteria显示文摘 | Marco Ventura Francesca Turroni Mary O’Connell Motherway John MacSharry Douwe van Sinderen | 2012 | Trends in Microbiology2012，，10： | 1 |
| 15 | Response surface methodology ( RSM ) as a tool for optimization in analytical chemistry 显示文摘 | Marcos A B Ricardo E S Eliane P O | 2008 | Talanta2008，，76： | 1 |
| 16 | Liver fibrosis assessment with semiquantitative indexes and image analysis quantification in sustained-responder and non-responder interferon-treated patients with chronic hepatitis C显示文摘 | Trinidad Caballero Alejandro Pérez-Milena Marco Masseroli Francisco O’Valle Francisco J Salmerón Raimundo M.G Del Moral Guillermo Sánchez-Salgado | 2001 | Journal of Hepatology2001，，5： | 1 |
| 17 | Electromagnetic Stimulation Combined with Aloe vera Increases Collagen Reorganization in Burn Repair显示文摘 | Sofia Poletti Leticia D. Lucke Fernanda O Bortolazzo Renata M. Acunha Marcos G. Mattos Femanda OG. Gaspi Thiago A. M. Andrade Maria Esmeria C. Amaral Andrea A .Aro Edson R Pimentel Marcelo AM. Esquisatto Fernanda A. S. Mendonga Glaucia M. T. Santos | 2018 | Journal of Pharmacy and Pharmacology2018，6，7： | 1 |
| 18 | Serotonin induced smooth muscle hyperplasia invarious forms of human pulmonary hypertension显示文摘 | Marcos E Fadel E Sanchez O | 2004 | Circ Res2004，94，9： | 1 |
| 19 | Generation and functional characterization of mouse monocyte-derived dendritic cells 显示文摘 | Marco W J Schreurs Andreas A O Eggert Annemiek J de Boer | 1999 | Eur J Immunol1999，29，9： | 1 |
| 20 | Photosynthetic changes and oxidative stress caused by iron ore dust deposition in the tropical CAM tree Clusia hilariana显示文摘 | Eduardo G P Marco A O Kacilda N K | | 0，，02： | 1 |
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