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| 1 | Epidemiological Evolution of Lung Cancer in the South of Spain from 1990 to 2010显示文摘Background: Changes in lung cancer has been characterized by the increase of cases among women and the increase in adenocarcinomas among other histological subtypes.Methods: Descriptive analysis of cases diagnosed with lung cancer in Hospital Virgen de las Nieves(Spain) from 1990 to 2010,based on five variables(age, sex, smoking, histology and pathological anatomy). The study establishes associations between these variables and compares the results with the literature.Results: 2,026 patients were diagnosed with lung cancer in this period; 1,838 were males(90.7%) and 188 women(9.3%); 1,892 patients(93.4%) were smokers or ex-smokers and 134(6.6%) had never smoked; the most frequent non-small cell histology types were squamous cell carcinoma and adenocarcinoma and it was the most frequent neoplasia in women and were associated with a lower tobacco consumption.Conclusion: The large majority of lung cancer cases is associated with a history of smoking tobacco and there are histopathological differences according to gender and cumulative tobacco smoke load. | Alberto Caballero Vázquez Ana Dolores Romero Ortiz Jose Manuel González de Vega San Román Raimundo García del Moral Bernardino Alcázar Navarrete | 2018 | 中国肺癌杂志2018，21，1： | 17 |
| 2 | Ventricular repolarization markers for predicting malignant arrhythmias in clinical practice显示文摘Malignant cardiac arrhythmias which result in sudden cardiac death may be present in individuals apparently healthy or be associated with other medical conditions. The way to predict their appearance represents a challenge for the medical community due to the tragic outcomes in most cases. In the last two decades some ventricular repolarization(VR) markers have been found to be useful to predict malignant cardiac arrhythmias in several clinical conditions. The corrected QT, QT dispersion, Tpeak-Tend, Tpeak-Tend dispersion and Tp-e/QT have been studied and implemented in clinical practice for this purpose. These markers are obtained from 12 lead surface electrocardiogram. In this review we discuss how these markers have demonstrated to be effective to predict malignant arrhythmias in medical conditions such as long and short QT syndromes, Brugada syndrome, early repolarization syndrome, acute myocardial ischemia, heart failure, hypertension, diabetes mellitus, obesity and highly trained athletes. Also the main pathophysiological mechanisms that explain the arrhythmogenic predisposition in these diseases and the basis for the VR markers are discussed. However, the same results have not been found in all conditions. Further studies are needed to reach a global consensus in order to incorporate these VR parameters in risk stratification of these patients. | Yaniel Castro-Torres Raimundo Carmona-Puerta Richard E Katholi | 2015 | World Journal of Clinical Cases2015，3，8： | 16 |
| 3 | Application of a biochemical and clinical model to predict individual survival in patients with end-stage liver disease显示文摘AIM:To investigate the capability of a biochemical and clinical model,BioCliM,in predicting the survival of cirrhotic patients.METHODS:We prospectively evaluated the survival of 172 cirrhotic patients.The model was constructed using clinical(ascites,encephalopathy and variceal bleeding) and biochemical(serum creatinine and serum total bilirubin) variables that were selected from a Cox proportional hazards model.It was applied to estimate 12-,52-and 104-wk survival.The model's calibration using the Hosmer-Lemeshow statistic was computed at 104 wk in a validation dataset.Finally,the model's validity was tested among an independent set of 85 patients who were stratified into 2 risk groups(low risk≤8 and high risk>8).RESULTS:In the validation cohort,all measures of fi t,discrimination and calibration were improved when the biochemical and clinical model was used.The proposed model had better predictive values(c-statistic:0.90,0.91,0.91) than the Model for End-stage Liver Disease(MELD) and Child-Pugh(CP) scores for 12-,52-and 104-wk mortality,respectively.In addition,the Hosmer-Lemeshow(H-L) statistic revealed that the biochemical and clinical model(H-L,4.69) is better calibrated than MELD(H-L,17.06) and CP(H-L,14.23).There were no significant differences between the observed and expected survival curves in the stratified risk groups(low risk,P=0.61;high risk,P=0.77).CONCLUSION:Our data suggest that the proposed model is able to accurately predict survival in cirrhotic patients. | Eduardo Vilar Gomez Luis Calzadilla Bertot Bienvenido Gra Oramas Enrique Arus Soler Raimundo Llanio Navarro Javier Diaz Elias Oscar Villa Jiménez Maria del Rosario Abreu Vazquez | 2009 | World Journal of Gastroenterology2009，15，22： | 6 |
| 4 | Nonmonotone adaptive trust region method based on simple conic model for unconstrained optimization显示文摘 | Lijuan ZHAO Wenyu SUN Raimundo J. B. de SAMPAIO | 2014 | Frontiers of Mathematics in China2014，9，5： | 3 |
| 5 | SEISMIC BEHAVIOUR OF A R/C WALL: NUMERICAL SIMULATION AND EXPERIMENTAL VALIDATION显示文摘 | Rui Faria Nelson Vila Pouca Raimundo Delgado | 2002 | Journal of Earthquake Engineering2002，，4： | 2 |
| 6 | A natural variant of the heme-binding signature (R441C) re- sulting in complete loss of function of CYP2D6显示文摘 | Klein K Tatzei S Raimundo S | 2007 | Drug Metab Dispos2007，35，8： | 1 |
| 7 | Personal protective clothing and safety of firefighters near a high intensity fire front显示文摘 | RAIMUNDO A M FIGUEIREDO A R | 2009 | Fire Safety Journal2009，44，： | 1 |
| 8 | A novel intronic mutation, 2988G>A, with high predictivi ty for impaired function of cytochrome P4502D6 in white subjects显示文摘 | Raimundo S Tescano C Klein K | 2004 | Clin Pharmacol Thr2004，76，2： | 1 |
| 9 | Spatial Determinants of Urban Residential Water Demand in Fortaleza, Brazil显示文摘 | Diego Maria André José Raimundo Carvalho | 2014 | Water Resources Management2014，，： | 1 |
| 10 | Influence of three different fiber supplemented enteral diets on bowel function and shortchain fatty acid production 显示文摘 | Kapadia S A Raimundo A H Grimble G K | 1995 | Journal of Parenteral and Enteral Nutrition1995，117，1： | 1 |
| 11 | Simultaneous Determination of Zn( I ) ,Cd( I ) and Hg( I ) in Water显示文摘 | Raimundo I M Narayanaswamy R | 2003 | Sensors and Actuators B2003，90，13： | 1 |
| 12 | Human leptin stimulates proliferation and activation of human circulating monocytes显示文摘 | Jose SA Raimundo G | 1999 | Cell Immunol1999，194，1： | 1 |
| 13 | Human leptin stimulates proliferation and activation of human circulating monocytes显示文摘 | Jose SA Raimundo G | 1999 | Cell Immunol1999，194，1： | 1 |
| 14 | Vitamin B12 in metformin-treated diabetic patients:a cross-sectional study in Brazil显示文摘 | Nervo M Lubini A Raimundo FV | 2011 | Rev Assoc Med Bras2011，57，1： | 1 |
| 15 | The use of soil respiration as an ecological indicator in arid ecosystems of the SE of Spain: Spatial variability and controlling factors显示文摘 | OYONARTE C Rey A Raimundo J | 2012 | Ecological Indicators2012，14，： | 1 |
| 16 | Construction and evaluation of a flow injection micro-analyser based on urethane-acrylate resin显示文摘 | Fonseea A Raimundo I M Jr Rohwedder J J | 2007 | Anal Chim Acta2007，603，： | 1 |
| 17 | Advances in GML for Geospatial Applications显示文摘 | Chang-Tien Lu Raimundo F. Santos Lakshmi N. Sripada Yufeng Kou | 2007 | GeoInformatica2007，，1： | 1 |
| 18 | Shear effects on hollow section piers under seismic actions: experimental and numerical analysis显示文摘 | Raimundo Delgado Pedro Delgado Nelson Vila Pouca António Arêde Patrício Rocha Aníbal Costa | 2009 | Bulletin of Earthquake Engineering2009，，2： | 1 |
| 19 | Synthesis of NiAl2O4 with high surface area as precursor of Ni nanopartieles for hydrogen production显示文摘 | NIELSON F P RIBEIRO RAIMUNDO C R NETO SILVIA F MOYA | 2010 | International Journal of Hydrogen Energy2010，35，11： | 1 |
| 20 | Transcatheter aortic valve implantation in very elderly patients: immediate results and medium term follow-up显示文摘ObjectiveTo 评估立即的 transcatheter 在有严重、征兆的大动脉的狭窄的很老的病人的大动脉的阀门培植(TAVI ) 结果和中期的后续(作为).MethodsThis multicenter,观察、未来的学习在三所医院里被执行。我们包括了连续很老(>85 年) 病人与作为严重由 TAVI 对待。主要端点是在包括的二 years.ResultsThe 研究从任何原因评估死亡率有一个平均数的 160 个连续病人 87 ± 变老;2.1 年(从 85 ~ 94 年的范围) 和 18.8%± 的吝啬的逻辑 EuroSCORE;11.2% 与 57 (35.6%) 病人得分 ≥20% 。程序的成功率是 97.5% ,与 25 (15.6%) 与主要流血经历尖锐复杂并发症的病人(最经常) 。全球死亡率在住院期间是 8.8%(n = 14 ) 并且 30 天的死亡率是 10%(n = 16 ) 。中部在时期上面列在后面是 252.24 ±232.17 天。在后续时期期间, 28 (17.5%) 病人们死了(他们中的 17 个由于心脏的原因) 。估计的二年全面、心脏的幸存率使用 Kaplan-Meier 方法分别地是 71% 和 86.4% 。比例的危险回归给看了的考克斯可变 EuroSCORE ≥20 是与全面 mortality.ConclusionsTAVI 联系的唯一的变量在很老的病人的一张选择人口安全、有效。我们的调查结果支持在病人的这个复杂的组的这个新过程的采纳。 | Isaac Pascual Antonio J Mu oz-García Diego López-Otero Pablo Avanzas Manuel F Jimenez-Navarro Belén Cid-Alvarez Raquel del Valle Juan H Alonso-Briales Raimundo Ocaranza-Sanchez José M Hemández Ramiro Trillo-Nouche César Morís | 2015 | Journal of Geriatric Cardiology2015，12，4： | 1 |
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