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| 1 | 在有分散的胃的息肉的病人的 colorectal 息肉的风险: 盒子控制研究显示文摘 AIM:To assess the risk of colonic polyps,adenomas and advanced neoplastic lesions(ANL) in patients with sporadic gastric polyps,especially those with fundic gland polyps(FGP).METHODS:Clinical records of patients who had performed an upper and a lower digestive endoscopy between September 2007 and August 2008 were retrospectively analyzed.A case-control study was carried out,calling patients with gastric polyps as 'cases' and patients without gastric polyps as 'controls'.The risk of colonic polyps,adenomas and ANL(villous component ≥ 25%,size ≥ 10 mm,or high grade dysplasia) was assessed [odds ratio(OR) and its corresponding 95%CI].RESULTS:Two hundred and forty seven patients were analyzed:78 with gastric polyps(cases) and 169 without gastric polyps(controls).Among the cases,the majority of gastric polyps were FGP(80%,CI:69-88) and hyperplastic(20%,CI:12-31);25% had colonic polyps(25% hyperplastic and 68% adenomas,from which 45% were ANL).Among the controls,20% had colonic polyps(31% hyperplastic and 63% adenomas,from which 41% were ANL).The patients with sporadic FGP had an OR of 1.56(CI:0.80-3.04) for colonic polyps,an OR of 1.78(CI:0.82-3.84) for colonic adenomas,and an OR of 0.80(CI:0.21-2.98) for ANL.Similar results were found in patients with gastric polyps in general.CONCLUSION:The results of this study did not show more risk of colorectal adenomas or ANL neither in patients with sporadic gastric polyps nor in those with FGP. | Daniel Gustavo Cimmino José Manuel Mella Pablo Luna Raquel González Lisandro Pereyra Carolina Fischer Adriana Mohaidle Beatriz Vizcaino Mario Andres Medrano Adrián Hadad Silvia Pedreira Luis Boerr | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，5： | 12 |
| 2 | Hepatic encephalopathy: Ever closer to its big bang显示文摘Hepatic encephalopathy(HE) is a neuropsychiatric disorder that commonly complicates the course of patients with liver disease. Despite the fact that the syndrome was probably first recognized hundreds of years ago, the exact pathogenesis still remains unclear. Minimal hepatic encephalopathy(MHE) is the earliest form of HE and is estimated to affect more that 75% of patients with liver cirrhosis. It is characterized by cognitive impairment predominantly attention, reactiveness and integrative function with very subtle clinical manifestations. The development of MHE is associated with worsen in driving skills, daily activities and the increase of overall mortality. Skeletal muscle has the ability to shift from ammonia producer to ammonia detoxifying organ. Due to its large size, becomes the main ammonia detoxifying organ in case of chronic liver failure and muscular glutaminesynthase becomes important due to the failing liver and brain metabolic activity. Gut is the major glutamine consumer and ammonia producer organ in the body. Hepatocellular dysfunction due to liver disease, results in an impaired clearance of ammonium and in its interorgan trafficking. Intestinal bacteria, can also represent an extra source of ammonia production and in cirrhosis, small intestinal bacterial overgrowth and symbiosis can be observed. In the study of HE, to get close to MHE is to get closer to its big bang; and from here, to travel less transited roads such as skeletal muscle and intestine, is to go even closer. The aim of this editorial is to expose this road for further and deeper work. | Pablo A Souto Ariel R Marcotegui Lisandro Orbea Juan Skerl Juan Carlos Perazzo | 2016 | World Journal of Gastroenterology2016，22，42： | 6 |
| 3 | Anemia and iron deficiency in gastrointestinal and liver conditions显示文摘Iron deficiency anemia(IDA) is associated with a number of pathological gastrointestinal conditions other than inflammatory bowel disease, and also with liver disorders. Different factors such as chronic bleeding, malabsorption and inflammation may contribute to IDA. Although patients with symptoms of anemia are frequently referred to gastroenterologists, the approach to diagnosis and selection of treatment as well as follow-up measures is not standardized and suboptimal. Iron deficiency, even without anemia, can substantially impact physical and cognitive function and reduce quality of life. Therefore, regular iron status assessment and awareness of the clinical consequences of impaired iron status are critical. While the range of options for treatment of IDA is increasing due to the availability of effective and well-tolerated parenteral iron preparations, a comprehensive overview of IDA and its therapy in patients with gastrointestinal conditions is currently lacking. Furthermore, definitions and assessment of iron status lack harmonization and there is a paucity of expert guidelines on this topic. This review summarizes current thinking concerning IDA as a common co-morbidity in specific gastrointestinal and liver disorders, and thus encourages a more unified treatment approach to anemia and iron deficiency, while offering gastroenterologists guidance on treatment options for IDA in everyday clinical practice. | Jürgen Stein Susan Connor Garth Virgin David Eng Hui Ong Lisandro Pereyra | 2016 | World Journal of Gastroenterology2016，22，35： | 5 |
| 4 | Prevalence of Plateau Iris in Primary Angle Closure Suspects显示文摘 | Rajesh S. Kumar Mani Baskaran Paul T.K. Chew David S. Friedman Swati Handa Raghavan Lavanya Lisandro M. Sakata Hon-Tym Wong Tin Aung | 2008 | Ophthalmology2008，，3： | 2 |
| 5 | Design and kinematic analysis of 3PSS - 1S wrist for needle insertion guidance 显示文摘 | Lisandro J Puglisi Roque J Saltaren German Rey Portoles | 2013 | Robotics and Autonomous Systems2013，61，5： | 1 |
| 6 | Immigrant Economic Adjustment and Family Organization: The Cuban Success Story Reexamined显示文摘 | Perez Lisandro | 1986 | International Migration Review 201986，，： | 1 |
| 7 | How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function显示文摘 | Lisandro H. Otero Alzoray Rojas-Altuve Leticia I. Llarrull Cesar Carrasco-López Malika Kumarasiri Elena Lastochkin Jennifer Fishovitz Matthew Dawley Dusan Hesek Mijoon Lee Jarrod W. Johnson Jed F. Fisher Mayland Chang Shahriar Mobashery Juan A. Hermoso | 2013 | Proceedings of the National Academy of Sciences2013，，： | 1 |
| 8 | Diagnostic approaches for diabetic cardiomyopathy and myocardial fibrosis显示文摘 | Lisandro Maya Francisco J. Villarreal | 2009 | Journal of Molecular and Cellular Cardiology2009，，： | 1 |
| 9 | Piaggio Ambiguous genitalia显示文摘 | lez and Lisandro A | 2006 | Curt Opin Urol2006，16，： | 1 |
| 10 | Calcium antagonists and antherosclerosis protection in hypertesion显示文摘 | Lisandro A Barquismeto Venezuela | 2003 | Am J Ther2003，10，6： | 1 |
| 11 | Tripalmitin and monoacylglycerols as modifiers in the crystallisation of palm oil显示文摘 | Rodrigo Corrêa Basso Ana Paula Badan Ribeiro Monise Helen Masuchi Luiz Antonio Gioielli Lireny A. Guaraldo Gon?alves Adenilson Oliveira dos Santos Lisandro Pavie Cardoso Renato Grimaldi | 2010 | Food Chemistry2010，，4： | 1 |
| 12 | Determinants of Lens Vault and Association With Narrow Angles in Patients From Singapore显示文摘 | Gavin S. Tan Mingguang He Wanting Zhao Lisandro M. Sakata Jialiang Li Monisha E. Nongpiur Raghavan Lavanya David S. Friedman Tin Aung | 2012 | American Journal of Ophthalmology2012，，1： | 1 |
| 13 | Prevalence,incidence,and etiology of epilepsies in rural honduras; the salama study显示文摘 | Marco TM Reyna MD Lisandro M | 2005 | Epilepsia2005，46，1： | 1 |
| 14 | Efficient coherent adaptive representations of monitored electric signals in power systems using damped sinusoids显示文摘 | Lisandro Lovisolo Eduardo A B da Silva Marco A M Rodrigues | 2005 | IEEE Transactions on Signal Processing2005，53，10： | 1 |
| 15 | Calcium antagonists and atherosclerosis protection in hypertesion 显示文摘 | Lisandro A Barquismeto Venezuela | 2003 | Am J Ther2003，10，6： | 1 |
| 16 | Thoracoscopic approach for congenital esophageal Stenosis 显示文摘 | Marcelo Martinez-Ferro Martin Rubio Lisandro Piaggio | 2006 | Journal of Pediatric Surgery2006，41，： | 1 |
| 17 | Design and kinematic analysis of 3PSS - IS wrist for needle insertion guidance 显示文摘 | Lisandro J Puglisi Roque J Saltaren Germ6n Rey Portol6s | 2013 | Robotics and Autonomous Systems2013，，61： | 1 |
| 18 | Efficient coherent adaptive representations of monitored electric signals in power systems using damped sinusoids显示文摘 | Lisandro L Eduardo A B da Silva Rodrigues Marco A M | 2005 | IEEE Trans on Signal Processing2005，53，10： | 1 |
| 19 | Colonic preparation before colonoscopy in constipated and non-constipated patients:A randomized study显示文摘AIM: To compare the efficacy of different doses of sodium phosphate(NaP) and polyethylenglicol(PEG) alone or with bisacodyl for colonic cleansing in constipated and non-constipated patients.METHODS: Three hundred and forty-nine patients,older than 18 years old,with low risk for renal damage and who were scheduled for outpatient colonoscopy were randomized to receive one of the following preparations(prep): 90 mL of NaP(prep 1);45 mL of NaP + 20 mg of bisacodyl(prep 2);4 L of PEG(prep 3) or 2 L of PEG + 20 mg of bisacodyl(prep 4).Randomization was stratified by constipation.Patients,endoscopists,endoscopists' assistants and data analysts were blinded.A blinding challenge was performed to endoscopist in order to reassure blinding.The primary outcome was the efficacy of colonic cleansing using a previous reported scale.Secondary outcomes were tolerability,compliance,side effects,endoscopist perception about the necessity to repeat the study due to an inadequate colonic preparation and patient overall perceptions.RESULTS: Information about the primary outcome was obtained from 324 patients(93%).There were no significant differences regarding the preparation quality among different groups in the overall analysis.Compliance was higher in the NaP preparations being even higher in half-dose with bisacodyl: 94%(prep 1),100%(prep 2),81%(prep 3) and 87%(prep 4)(2 vs 1,3 and 4,P < 0.01;1 vs 3,4,P < 0.05).The combination of bisacodyl with NaP was associated with insomnia(P = 0.04).In non-constipated patients the preparation quality was also similar between different groups,but endoscopist appraisal about the need to repeat the study was more frequent in the half-dose PEG plus bisacodyl than in whole dose NaP preparation: 11%(prep 4) vs 2%(prep 1)(P < 0.05).Compliance in this group was also higher with the NaP preparations: 95%(prep 1),100%(prep2) vs 80%(prep 3)(P < 0.05).Bisacodyl was associated with abdominal pain: 13%(prep 1),31%(prep 2),21%(prep 3) and 29%(prep 4),(2,4 vs 1,2,P < 0.05).In constipated patients the combination of NaP plus bisacodyl presented higher rates of satisfactory colonic cleansing than whole those PEG: 95%(prep 2) vs 66%(prep 3)(P = 0.03).Preparations containing bisacodyl were not associated with adverse effects in constipated patients.CONCLUSION: In non-constipated patients,compliance is higher with NaP preparations,and bisacodyl is related to adverse effects.In constipated patients NaP plus bisacodyl is the most effective preparation. | Lisandro Pereyra Daniel Cimmino Carlos González Malla Mariano Laporte Nicolás Rotholtz Carlos Peczan Sandra Lencinas Silvia Pedreira Hugo Catalano Luis Boerr | 2013 | World Journal of Gastroenterology2013，19，31： | 1 |
| 20 | Interaction of enterocyte fabps with phospholipid membranes: clues for specific physiological roles 显示文摘 | Lisandro J Gisela R Maria X | 2011 | Biochim Biophys Acta2011，1811，78： | 1 |
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