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		题名	作者	年代	出处	被引量
	1	hsa-miR-29c and hsa-miR-135b differential expression aspotential biomarker of gastric carcinogenesis显示文摘AIM: To investigate the expression profiles of hsa-mi R-29 c and hsa-mi R-135 b in gastric mucosal samples and their values as gastric carcinogenesis biomarkers. METHODS: The expression levels of hsa-mi R-29 c and hsa-mi R-135 b in normal gastric mucosa, non-atrophic chronic gastritis, intestinal metaplasia and intestinaltype gastric adenocarcinoma were analysed using quantitative real-time PCR. The difference between hsa-mi R-29 c and hsa-mi R-135 b expression profiles in the grouped samples was evaluated by ANOVA and Student's t-test tests. The results were adjusted for multiple testing by using Bonferroni's correction. P values ≤ 0.05 were considered statistically significant. To evaluate hsa-mi R-29 c and hsa-mi R-135 b expressions as potential biomarkers of gastric carcinogenesis, we performed a receiver operating characteristic curve analysis and the derived area under the curve, and a Categorical Principal Components Analysis. In silico identification of the genetic targets of hsa-mi R-29 c and hsa-mi R-135 b was performed using different prediction tools, in order to identify possible genes involved in gastric carcinogenesis.RESULTS: The expression levels of hsa-mi R-29 c were higher in normal gastric mucosal samples, and decreased progressively in non-atrophic chronic gastritis samples, intestinal metaplasia samples and intestinal-type gastric adenocarcinoma samples. The expression of hsa-mi R-29 c in the gastric lesions showed that non-atrophic gastritis have an intermediate profile to gastric normal mucosa and intestinal-type gastric adenocarcinoma, and that intestinal metaplasia samples presented an expression pattern similar to that in intestinal-type gastric adenocarcinoma. This micro RNA(mi RNA) has a good discriminatory accuracy between normal gastric samples and(1) intestinal-type gastric adenocarcinoma; and(2) intestinal metaplasia, and regulates the DMNT3 A oncogene. hsa-mi R-135 b is up-regulated in non-atrophic chronic gastritis and intestinal metaplasia samples and down-regulated in normal gastric mucosa and intestinal-type gastric adenocarcinoma samples. Non-atrophic chronic gastritis and intestinal metaplasia are significantly different from normal gastric mucosa samples. hsa-mi R-135 b expression presented a greater discriminatory accuracy between normal samples and gastric lesions. This mi RNA was associated with Helicobacter pylori presence in non-atrophic chronic gastritis samples and regulates the APC and KLF4 tumour suppressor genes.CONCLUSION: Our results provide evidence of epigenetic alterations in non-atrophic chronic gastritis and intestinal metaplasia and suggest that hsa-mi R-29 c and hsa-mi R-135 b are promising biomarkers of gastric carcinogenesis.	Amanda Ferreira Vidal Aline MP Cruz Leandro Magalhães Adenilson L Pereira Ana KM Anaissi Nélisson CF Alves Paulo JBS Albuquerque Rommel MR Burbano Samia Demachki Ândrea Ribeiro-dos-Santos	2016	World Journal of Gastroenterology2016，22，6：	7
	2	Joint dynamics modeling and parameter identification for space robot applications 显示文摘	Adenilson R da Silva Luiz C	2007	Mathematical Problems in Engineering2007，1，10：	1
	3	Structural and Magnetic Study ofthe MnAs Magnetocaloric Compound显示文摘	Fabiana Cristina Nascimento Adenilson Oliveira dos Santos Ariana de Campos	2006	Materials Research2006，9，1：	1
	4	Joint dynamics modeling and parameter identification for space robot applications 显示文摘	Adenilson R Luiz C	2007	Mathematical Problems in Engineering2007，1，10：	1
	5	Tripalmitin and monoacylglycerols as modifiers in the crystallisation of palm oil显示文摘	Rodrigo Corrêa Basso Ana Paula Badan Ribeiro Monise Helen Masuchi Luiz Antonio Gioielli Lireny A. Guaraldo Gon?alves Adenilson Oliveira dos Santos Lisandro Pavie Cardoso Renato Grimaldi	2010	Food Chemistry2010，，4：	1
	6	Joint dynamics modeling and parameter identification for space robot applications显示文摘	Da Silva Adenilson R Schafer Bernd De Souza Luiz C Gadelha	2001	Advances in the Astronautical Sciences2001，108，2：	1
	7	Direct evidence of traps controlling the carriers transport in SnO_(2) nanobelts显示文摘This work reports on direct evidence of localized states in undoped SnO_2 nanobelts.Effects of disorder and electron localization were observed in Schottky barrier dependence on the temperature and in thermally stimulated currents.A transition from thermal activation to hopping transport mechanisms was also observed.The energy levels found by thermally stimulated current experiments were in close agreement with transport data confirming the role of localization in determining the properties of devices.	Olivia M.Berengue Adenilson J.Chiquito	2017	Journal of Semiconductors2017，38，12：	0
	8	Alginate Matrix of MDA-MB-231 Breast Cancer Cell 3D Culturing Alters CD44 and CD24 mRNA Levels and Induces ALDH1 Expression显示文摘	Layane Duarte e Souza Elisa Raquel Anastacio Ferraz Isis Soares Salviano Adenilson Souza da Fonseca Israel Felzenzswalb Andre Luiz Mencalha	2017	Journal of Life Sciences2017，11，5：	0

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