|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Shipping emissions associated with increased cardiovascular hospitalizations显示文摘 | Linwei Tian Kin-fai Ho Peter K.K. Louie Hong Qiu Vivian C. Pun Haidong Kan Ignatius T.S. Yu Tze Wai Wong | 2013 | Atmospheric Environment2013,,: | 1 |
| 2 | Responses of the functional structure of soil microbial community to livestock grazing in the T ibetan alpine grassland显示文摘 | Yunfeng Yang Linwei Wu Qiaoyan Lin Mengting Yuan Depeng Xu Hao Yu Yigang Hu Jichuang Duan Xiangzhen Li Zhili He Kai Xue Joy van Nostrand Shiping Wang Jizhong Zhou | 2012 | Glob Change Biol2012,,2: | 1 |
| 3 | Engineered platelets-based drug delivery platform for targeted thrombolysis显示文摘Thrombolytic agents have thus far yielded limited therapeutic benefits in the treatment of thrombotic disease due to their short half-life,low targeting ability,and association with serious adverse reactions,such as bleeding complications.Inspired by the natural roles of platelets during thrombus formation,we fabricated a platelet-based delivery system(NO@uPA/PLTs)comprising urokinase(uPA)and arginine(Arg)for targeted thrombolysis and inhibition of re-embolism.The anchoring of uPA to the platelet surface by lipid insertion increased the thrombotic targeting and in vivo circulation duration of uPA without disturbing platelet functions.Nitric oxide(NO)generated by the loaded Arg inhibited platelet aggregation and activation at the damaged blood vessel,thereby inhibiting re-embolism.NO@uPA/PLTs effectively accumulated at the thrombi in pulmonary embolism and carotid artery thrombosis model mice and exerted superior thrombolytic efficacy.In addition,the platelet delivery system showed excellent thrombus recurrence prevention ability in a mouse model of secondary carotid artery injury.The coagulation indicators in vivo showed that the platelet-based uPA and NO co-delivery system possessed a low hemorrhagic risk,providing a promising tool for rapid thrombolysis and efficient inhibition of posttreatment re-embolism. | Songli Wang Ruifeng Wang Nana Meng Linwei Lu Jun Wang Jianfen Zhou Jiasheng Lu Qianzhu Xu Cao Xie Changyou Zhan Yao Li Yang Yu Weiyue Lu Min Liu | 2022 | Acta Pharmaceutica Sinica B2022,12,4: | 1 |
| 4 | Engineering in-plane silicon nanowire springs for highly stretchable electronics显示文摘Crystalline silicon(c-Si) is unambiguously the most important semiconductor that underpins the development of modern microelectronics and optoelectronics, though the rigid and brittle nature of bulk c-Si makes it difficult to implement directly for stretchable applications. Fortunately, the one-dimensional(1 D) geometry, or the line-shape, of Si nanowire(SiNW) can be engineered into elastic springs, which indicates an exciting opportunity to fabricate highly stretchable 1 D c-Si channels. The implementation of such line-shape-engineering strategy demands both a tiny diameter of the SiNWs, in order to accommodate the strains under large stretching, and a precise growth location, orientation and path control to facilitate device integration. In this review, we will first introduce the recent progresses of an in-plane self-assembly growth of SiNW springs, via a new in-plane solid-liquidsolid(IPSLS) mechanism, where mono-like but elastic SiNW springs are produced by surface-running metal droplets that absorb amorphous Si thin film as precursor. Then, the critical growth control and engineering parameters, the mechanical properties of the SiNW springs and the prospects of developing c-Si based stretchable electronics, will be addressed. This efficient line-shape-engineering strategy of SiNW springs, accomplished via a low temperature batch-manufacturing, holds a strong promise to extend the legend of modern Si technology into the emerging stretchable electronic applications, where the high carrier mobility, excellent stability and established doping and passivation controls of c-Si can be well inherited. | Zhaoguo Xue Taige Dong Zhimin Zhu Yaolong Zhao Ying Sun Linwei Yu | 2018 | Journal of Semiconductors2018,39,1: | 1 |
| 5 | Preface to the Special Issue on Si-Based Materials and Devices显示文摘It has been well known that the development of microelectronic and integrated circuit(IC),mainly based on silicon materials,have changed the way of our life dramatically and accelerated the development and innovation of new technologies.With the increase of integration density in ICs,the gate lengths of transistors are now scaled down to 7 nm,leading | Chuanbo Li Jinsong Xia Linwei Yu | 2018 | Journal of Semiconductors2018,39,6: | 0 |
| 6 | 香港来源特异性颗粒物对缺血性心脏病急诊住院治疗的不同影响显示文摘[背景]缺血性心脏病(IHD)是一个重要的公共卫生问题。虽然许多流行病学研究已经报道了颗粒物(PM)的质量对IHD具有不利影响的证据,但是对于不同来源PM的潜在影响的认识仍然存在显著的空白。与PM的大小一样,PM的来源也可能影响其毒理特性。 | Vivian Chit Pun Ignatius Tak-sun Yu Kin-fai Ho Hong Qiu Zhiwei Sun Linwei Tian | 2014 | 环境与职业医学2014,31,7: | 0 |
| 7 | Superior Iodine Uptake Capacity Enabled by an Open Metal-Sulfide Framework Composed of Three Types of Active Sites显示文摘Efficient adsorption of gaseous radioiodine is pivotal for the sustainable development of nuclear energy and the long-termradiation safety of the ecological system.However,state-of-the-art adsorbents(e.g.metal-organic frameworks and covalent-organic frameworks)currently under exploration suffer severely from limited adsorption capacity,especially under a real-world scenariowith extremely lowradioiodine concentration and elevated temperature.This mostly originates from the relatively weak sorption driving forces mainly determinedby the iodine-adsorbent interaction consistingof noncovalent interactionswith a small fraction of strong chemical bonding.Here,we document the discovery of an open metal-sulfide framework((NH_(4))_(2)(Sn_(3)S_(7)),donated as SCU-SnS)constructed by three different types of active sites as a superior iodine adsorbent.Benefiting from the ability of iodine for pre-enrichment into the framework by charge-balancing NH_(4)^(+)through N-H···I interaction,the efficient reduction of I^(2)affording I^(-)by S^(2-),and extremely high binding affinity between Sn_(4)^(+)and I^(-),SCU-SnS exhibit a record-breaking iodine adsorption capacity(2.12 g/g)under dynamic breakthrough conditions and the highest static capacity(6.12 g/g)among all reported inorganic adsorbents,both at 348 K.Its facile synthesis and low cost endow SCU-SnS with powerful application potential for the nuclear industry. | Yugang Zhang Linwei He Tingting Pan Jian Xie Fuqi Wu Xinglong Dong Xia Wang Lixi Chen Shicheng Gong Wei Liu Litao Kang Junchang Chen Lanhua Chen Long Chen Yu Han Shuao Wang | 2023 | CCS Chemistry2023,5,7: | 0 |
| 8 | Toward monolithic growth integration of nanowire electronics in 3D architecture:a review显示文摘Quasi-one-dimensional(1D)semiconducting nanowires(NWs),with excellent electrostatic control capability,are widely regarded as advantageous channels for the fabrication of high-performance microelectronics,memories,and sensors.For example,the latest Si field-effect-transistor(FET)technology nodes, | Lei LIANG Ruijin HU Linwei YU | 2023 | Science China(Information Sciences)2023,66,10: | 0 |
| 9 | Contrasting behaviors of^(210)Po,^(210)Pb and^(234)Th in the East China Sea during a severe red tide:Enhanced scavenging and promoted fractionation显示文摘^(210)Po,^(210)Pb,and^(234)Th were determined in water columns of the East China Sea(ECS)to investigate their biogeochemical behaviors during a severe red tide event.Dissolved^(210)^(210)radionuclides were influenced by particle content effect and particle composition based on distribution coefficient(Kd)vs.total suspended matter(TSM)content and Kd vs.ratios of particulate organic carbon and total suspended matter contents(POC/TSM content ratios).The peaks of mass specific activities of^(210)Po,^(210)Pb,and^(234)Th indicated that degraded particles could have an intensified enrichment ability for radionuclides compared with the surficial suspended matters.Fractionation factor of^(210)Po and^(210)Pb(FPo/Pb)(>1)and fractionation factor of^(210)Po and^(234)Th(FPo/Th)(>1)were much higher at algal blooming regions than that at non-blooming stations,indicating that algal blooms promoted the fractionation of^(210)Po against^(210)Pb and^(234)Th,and proving that^(210)Po exhibited a stronger affinity for biogenic particles than^(210)Pb and^(234)Th when POC content increased in the sea.POC/^(210)Po,POC/^(210)Pb and POC/^(234)Th ratios(content/activity ratios)sharply decreased with depth in both algal bloom and non-bloom stations.The outbreak of algal bloom promoted the complexity of suspended particles and increased the variability of POC/tracer ratios(content/activity ratios)in the different depth of the shallow seas.More considerations should be taken to the difficulty of the selection of export interface and the suitable tracers when algal blooming occurs. | Qiangqiang Zhong Linwei Li Viena Puigcorbé Dekun Huang Tao Yu Jinzhou Du | 2022 | Acta Oceanologica Sinica2022,41,8: | 0 |
| 10 | All-stage targeted therapy for the brain metastasis from triple-negative breast cancer显示文摘Brain metastasis is a common and serious complication of breast cancer,which is commonly associated with poor survival and prognosis.In particular,the treatment of brain metastasis from triplenegative breast cancer(BM-TNBC)has to face the distinct therapeutic challenges from tumor heterogeneity,circulating tumor cells(CTCs),blood-brain barrier(BBB)and blood-tumor barrier(BTB),which is in unmet clinical needs.Herein,combining with the advantages of synthetic and natural targeting moieties,we develop a“Y-shaped”peptide pVAP-decorated platelet-hybrid liposome drug delivery system to address the all-stage targeted drug delivery for the whole progression of BM-TNBC.Inherited from the activated platelet,the hybrid liposomes still retain the native affinity toward CTCs.Further,the peptide-mediated targeting to breast cancer cells and transport across BBB/BTB are demonstrated in vitro and in vivo.The resultant delivery platform significantly improves the drug accumulation both in orthotopic breast tumors and brain metastatic lesions,and eventually exhibits an outperformance in the inhibition of BM-TNBC compared with the free drug.Overall,this work provides a promising prospect for the comprehensive treatment of BMTNBC,which could be generalized to other cell types or used in imaging platforms in the future. | Zimiao Luo Sunyi Wu Jianfen Zhou Weixia Xu Qianzhu Xu Linwei Lu Cao Xie Yu Liu Weiyue Lu | 2023 | Acta Pharmaceutica Sinica B2023,13,1: | 0 |