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| 1 | Association of three single nucleotide polymorphisms of ESR1 with breast cancer susceptibility:a meta-analysis显示文摘Expression of estrogen receptors is correlated with breast cancer risk,but inconsistent results have been reported.To clarify potential estrogen receptor(ESR)-related breast cancer risk,we analyzed genetic variants of ESR1 in association with breast cancer susceptibility.We performed a meta-analysis to investigate the association between rs2234693,rs1801132,and rs2046210(single nucleotide polymorphisms of ESR1),and breast cancer risk.Our analysis included 44 case-control studies.For rs2234693,the CC genotype had a higher risk of breast cancer compared to the TT or CT genotype.For rs2046210,the AA,GA,or GA + GG genotype had a much higher risk compared to the GG genotype.No significant association was found for the rs 1801132 polymorphism with breast cancer risk.This meta-analysis demonstrates association between the rs2234693 and rs2046210 polymorphisms of ESR1 and breast cancer risk.The correlation strength between rs2234693 and breast cancer susceptibility differs in subgroup assessment by ethnicity. | Xu Hu Linfei Jiang Chenhui Tang Yuehong Ju Li Jiu Yongyue Wei Li Guo Yang Zhao | 2017 | The Journal of Biomedical Research2017，31，3： | 4 |
| 2 | The principle of measuring unusual change of underground mass by optical astrometric instrument显示文摘Optical observations from a ground-based astrometric instrument provide a unique set of data sensitive to variations of local plumb line, which represent the change of local gravitational field on the ground. The local gravitational change could be caused by density variation or movement of underground mass in addition to tidal action. Earthquake was found to be related with gravitational change. A seismic zone could have abnormal underground material density, causing the variation of plume line on the ground. In this frame, the astrometric telescope can measure the variation of local plumb line by observing the local astronomical longitudes and latitudes from stars in the Hipparcos catalog. In this study, we estimate the deflection angle of the plumb line on a ground site, and give a relation between the angle, abnormal mass and site distance (depth and horizontal distance). Then we derive the abnormality of underground material density using the plumb lines measured at different sites, and study the earthquake gestation, development and occurrence. Using the deflection angles of plumb lines observed at two sites, we give a method to calculate the mass and the center of gravity of underground materials. We also estimate the abnormal masses of latent seismic zones with different energy, using thermodynamic relations, and introduce a new optical astrometric instrument we had developed. | Wang Jiancheng Chen Linfei Yang Lei Cheng Xiangming Su Jie Li Binghua Mao Wei Tie Qiongxian | 2012 | Geodesy and Geodynamics2012，3，4： | 4 |
| 3 | A subunit vaccine based on rH-NS induces protection against Mycobacterium tuberculosis infection by inducing the Thl immune response and activating macrophaqes显示文摘 | Yuan Liu Suting Chen Bowen Pan Zhu Guan Zhenjun Yang Linfei Duan Hong Cai | 2016 | Acta Biochimica et Biophysica Sinica2016，48，10： | 2 |
| 4 | Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Monlb显示文摘 | Ximing Shao Yi Liu Qian Yu Zhihao Ding Wenyu Qian Lei Zhang Jianchao Zhang Nan Jiang Linfei Gui Zhiheng Xu Yang Hong Yifan Ma Yanjie Wei Xiaoqing Liu Changan Jiang Minyan Zhu Hongchang Li Huashun Li | 2016 | Cell Research2016，26，5： | 1 |
| 5 | High-pressure investigations on the isostructural phase transition and metallization in realgar with diamond anvil cells显示文摘The high-pressure structural,vibrational and electrical properties for realgar were investigated by in-situ Raman scattering and electrical conductivity experiments combined with first-principle calculations up to~30.8 GPa.It was verified that realgar underwent an isostructural phase transition at~6.3 GPa and a metallization at a higher pressure of~23.5 GPa.The isostructural phase transition was well evidenced by the obvious variations of Raman peaks,electrical conductivity,crystal parameters and the As–S bond length.The phase transition of metallization was in closely associated with the closure of bandgap rather than caused by the structural phase transition.And furthermore,the metallic realgar exhibited a relatively low compressibility with the unit cell volume V_(0)=718.1.4Å^(3)and bulk modulus B_(0)=36.1 GPa. | Linfei Yang Lidong Dai Heping Li Haiying Hu Meiling Hong Xinyu Zhang Pengfei Liu | 2021 | Geoscience Frontiers2021，12，2： | 1 |
| 6 | pH-dependent deg- radation of acid orange Ⅱ by zero-valent iron in presence of oxygen 显示文摘 | He Chun Yang Jiannan Zhu Linfei | 2013 | Separation and Purification Technology2013，117，： | 1 |
| 7 | Functional divergence of oligoadenylate synthetase 1(OAS1)proteins in Tetrapods显示文摘OASs play critical roles in immune response against virus infection by polymerizing ATP into 2-5 As,which initiate the classical OAS/RNase L pathway and induce degradation of viral RNA.OAS members are functionally diverged in four known innate immune pathways(OAS/RNase L,OASL/IRF7,OASL/RIG-I,and OASL/cGAS),but how they functionally diverged is unclear.Here,we focus on evolutionary patterns and explore the link between evolutionary processes and functional divergence of Tetrapod OAS1.We show that Palaeognathae and Primate OAS1 genes are conserved in genomic and protein structures but differ in function.The former(i.e.,ostrich)efficiently synthesized long 2-5 A and activated RNase L,while the latter(i.e.,human)synthesized short 2-5 A and did not activate RNase L.We predicted and verified that two in-frame indels and one positively selected site in the active site pocket contributed to the functional divergence of Palaeognathae and Primate OAS1.Moreover,we discovered and validated that an in-frame indel in the C-terminus of Palaeognathae OAS1 affected the binding affinity of ds RNA and enzymatic activity,and contributed to the functional divergence of Palaeognathae OAS1 proteins.Our findings unravel the molecular mechanism for functional divergence and give insights into the emergence of novel functions in Tetrapod OAS1. | Xiaoxue Wang Jiaxiang Hu Linfei Song Enguang Rong Chenghuai Yang Xiaoyun Chen Juan Pu Honglei Sun Chuze Gao David WBurt Jinhua Liu Ning Li Yinhua Huang | 2022 | Science China(Life Sciences)2022，65，7： | 1 |
| 8 | Preparat ion of supercapacitor electrodes through selection of graphene surface functionalities显示文摘 | Lai Linfei Yang Huanping Wang Liang | 2012 | ACSNano2012，6，： | 1 |
| 9 | Influences of graphene oxide support on the electrochemical performances of graphene oxide-MnO2 nanocomposites显示文摘 | Huanping Yang Jian Jiang Weiwei Zhou Linfei Lai Lifei Xi Yeng Lam Zexiang Shen Bahareh Khezri Ting Yu | 2011 | Nanoscale Research Letters2011，，1： | 1 |
| 10 | Safety Evaluation of Concrete Structures Based on a Novel Energy Criterion显示文摘In this article,the post-peak softening stage of the constitutive relation and the elastic stiffness degradation of concrete are investigated,and a highly reasonable constitutive relation curve is proposed.At the material level,the energy change in the concrete failure process is studied based on the different stress-strain curves of concrete under uniaxial tension and compression.The concrete failure criterion based on elastic strain energy density is deemed suitable and consistent with the experimental phenomena.The hysteresis phenomenon(lags behind the peak strength)is also discussed.At the structure level,the strength reduction method is employed for the stability analysis,the energy change in the failure process of the Long Xi-Kou Dam is examined,and the results show that the dam failure criterion based on elastic strain energy shows a greater significance in practical applications compared with other conventional structural failure criteria in engineering.This criterion is objective and can avoid subjective arbitrariness. | Qiang Tong Qingwen Ren Lei Shen Linfei Zhang Yin Yang | 2018 | Computer Modeling in Engineering & Sciences2018，，1： | 0 |
| 11 | Study of Panjin Wetlands Along Bohai Coast:(Ⅰ) the Information System of Wetlands Based on 3S Technique显示文摘Based on previous studies on Panjin wetlands along the coast of the Bohai Sea,this paper adopts RS,GIS and GPS tech-niques and establishes the information system for Panjin wetlands. The system involves many functions,such as identification and classification of wetlands,calculation of the area of wetlands and storage of the information of the wetland management. Moreover,our study indicates that remote sensing technique is a useful tool for great macrography,speediness and accuracy to carry out the extraction,analysis,management and handling of information together with geography information system,which has prospective applications in similar kinds of research. | WANG Tieliang ZHOU Linfei YANG Peiqi ZHAO Bo | 2008 | Journal of Ocean University of China2008，7，4： | 0 |
| 12 | SPAG4L/SPAG4Lβ interacts with Nesprin2 to participate in the meiosis of spermatogenesis显示文摘SUN domain proteins are identified as a novel family of nuclear envelope proteins which are involved in spermatogenesis. SPAG4L is identified as the fifth member of this family. Previous studies have revealed that SPAG4L is involved in spermatogenesis and the mutations occurring in SPAG4L will lead to male infertility. However, the transcriptions of SPAG4L and its interacting proteins in the testis are still unclear. In this study, we identified a shorter transcript variant of SPAG4L, named SPAG4Lβ, in human testis by northern blot and reverse transcription-polymerase chain reaction. Bioinformatics analysis showed that it encodes a protein consisting of 311 amino acids, and subcellular localization analysis revealed that it is mainly expressed in the cytoplasm. In situ hybridization and immunofluorescence assay revealed that SPAG4L/SPAG4Lβ is involved in meiosis. Furthermore, co-IP results demonstrated that SPAG4L/SPAG4Lβ interacts with Nesprin2, a KASH domain protein to form the LINC (linker of nucleoskeleton and cytoskeleton) complexes. Immunofluorescence results revealed that the LINC complexes of Spag4l/Nesprin2 in mouse are involved in spermatocyte division. Our data indicated that SPAG4L/SPAG4Lβ may play an important role in the meiotic process. | Xiaohua Li Yong Wu Lihua Huang Linfei Yang Xiaowei Xing | 2019 | Acta Biochimica et Biophysica Sinica2019，51，7： | 0 |
| 13 | Advances in probing single biomolecules: From DNA bases to glycans显示文摘Imaging biomolecules in real space is crucial for gaining a comprehensive understanding of the properties and functions of biological systems at the most fundamental level.Among the various imaging techniques available for biomolecules and their assembled nanostructures,scanning probe microscopy(SPM)provides a powerful and nondestructive imaging option.SPM is unique in visualizing intrinsically disordered biomolecules at the nanometer scale(e.g.,glycans).This review highlights recent achievements in studying biomolecules using SPM technique,focusing on DNA bases,amino acids,proteins,and glycans.The atomic-level analysis of biomolecules made possible by SPM allows for a more accurate definition of the local structure–property relationship.High-resolution SPM imaging of single biomolecules offers a new way to study basic processes of life at the molecular level. | Baofei Hou Teng Zhang Huixia Yang Xu Han Liwei Liu Linfei Li Cesare Grazioli Xu Wu Nan Jiang Yeliang Wang | 2023 | Interdisciplinary Materials2023，2，4： | 0 |
| 14 | Study of Panjin Wetlands Along Bohai Coast(Ⅱ):Ecological Water Requirement of Shuangtaizi Estuarine Wetland显示文摘Shuangtaizi estuarine wetland along the Bohai Sea coast,the biggest bulrush wetland in the world,has been listed in 'The Record of Important International Wetland Conservation District'. Taking the year of 2 000 as an example,the minimum,the most suitable and the maximum ecological water requirement of Shuangtaizi estuarine wetland are calculated in this paper based on both ecological theory and Geological Information System technology. In addition,the remote sensing technique is adopted in the data acquisition process. Moreover,the total water requirement and the unit area water requirement for different wetland types are obtained. The result is very important for water resources planning,ecological conservation and regional agriculture structure adjustment in Shuangtaizi. Meanwhile,this study can serve as a useful example for calculating the ecological water requirement in other similar estuarine wetlands. | WANG Tieliang ZHOU Linfei ZHAO Bo YANG Peiqi | 2009 | Journal of Ocean University of China2009，8，2： | 0 |
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