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| 1 | FINITE ELEMENT MODELLING OF COMPLEX 3D STATIC AND DYNAMIC CRACK PROPAGATION BY EMBEDDING COHESIVE ELEMENTS IN ABAQUS显示文摘This study proposes an algorithm of embedding cohesive elements in Abaqus and develops the computer code to model 3D complex crack propagation in quasi-brittle materials in a relatively easy and efficient manner.The cohesive elements with softening traction-separation relations and damage initiation and evolution laws are embedded between solid elements in regions of interest in the initial mesh to model potential cracks.The initial mesh can consist of tetrahedrons,wedges,bricks or a mixture of these elements.Neither remeshing nor objective crack propagation criteria are needed.Four examples of concrete specimens,including a wedge-splitting test,a notched beam under torsion,a pull-out test of an anchored cylinder and a notched beam under impact,were modelled and analysed.The simulated crack propagation processes and load-displacement curves agreed well with test results or other numerical simulations for all the examples using initial meshes with reasonable densities.Making use of Abaqus's rich pre/post-processing functionalities and powerful standard/explicit solvers,the developed method offers a practical tool for engineering analysts to model complex 3D fracture problems. | Xiangting Su Zhenjun Yang Guohua Liu | 2010 | Acta Mechanica Solida Sinica2010，23，3： | 23 |
| 2 | Craniocerebral injury promotes the repair of peripheral nerve injury显示文摘The increase in neurotrophic factors after craniocerebral injury has been shown to promote fracture healing. Moreover, neurotrophic factors play a key role in the regeneration and repair of peripheral nerve. However, whether craniocerebral injury alters the repair of peripheral nerve injuries remains poorly understood. Rat injury models were established by transecting the left sciatic nerve and using a free-fall device to induce craniocerebral injury. Compared with sciatic nerve injury alone after 6–12 weeks, rats with combined sciatic and craniocerebral injuries showed decreased sciatic functional index, increased recovery of gastrocnemius muscle wet weight, recovery of sciatic nerve ganglia and corresponding spinal cord segment neuron morphologies, and increased numbers of horseradish peroxidase-labeled cells. These results indicate that craniocerebral injury promotes the repair of peripheral nerve injury. | Wei Wang Jun Gao Lei Na Hongtao Jiang Jingfeng Xue Zhenjun Yang Pei Wang | 2014 | Neural Regeneration Research2014，9，18： | 15 |
| 3 | Phaeocystis globosa Bloom Monitoring: Based on P. globosa Induced Seawater Viscosity Modification Adjacent to a Nuclear Power Plant in Qinzhou Bay, China显示文摘The mucus produced by the outbreak of Phaeocystis globosa in the adjacent waters of the Fangchenggang Nuclear Power Plant(FCGNPP) in China has blocked the entrance of the cooling water filtration system of the FCGNPP, and posed a threat to the safe operation of the FCGNPP. At present, there is no related research on whether the changes in seawater viscosity could be used as a new method for monitoring and providing early warning of P. globosa tide. During a complete red tide cycle, the temporal and spatial changes in the hydrological conditions(temperature, salinity, dissolved oxygen), chlorophyll-a(Chl-a), composition and abundance of phytoplankton, number and size of P. globose colonies, concentration of transparent exopolymer particles(TEP) and the seawater viscosity were measured in this study. The results indicate that there was an extremely significant negative correlation between the physical seawater viscosity η_(T,S) and temperature, and the correlation coefficient reached-0.998. The biological seawater viscosity η_(Bio) was positively correlated with the number of P. globosa colonies, and the correlation coefficients is 0.747. Because the increase in phytoplankton abundance, especially during the outbreak of P. globosa and a large amount of mucus produced by the colonies could significantly increase seawater viscosity, we suggest that biological factors were the main reasons for the increase in seawater viscosity. The η_(Bio) was completely consistent with the occurrence process of P. globosa bloom and could be used as a valuable index for P. globosa bloom monitoring. | KANG Zhenjun YANG Bin LAI Junxiang NING Yi ZHONG Qiuping LU Dongliang LIAO Riquan WANG Pei Solomon Felix Dan SHE Zhicai JIA Zhen LAO Yanling LI Nan | 2020 | Journal of Ocean University of China2020，19，5： | 5 |
| 4 | Multiscale modeling of mechanical behavior and failure mechanism of 3D angle-interlock woven aluminum composites subjected to warp/weft directional tension loading显示文摘The mechanical behavior and progressive damage mechanism of novel aluminum matrix composites reinforced with 3D angle-interlock woven carbon fibers were investigated using a multiscale modeling approach.The mechanical properties and failure of yarns were evaluated using a microscale model under different loading scenarios.On this basis,a mesoscale model was developed to analyze the tensile behavior and failure mechanism of the composites.The interfacial decohesion,matrix damage,and failure of fibers and yarns were incorporated into the microscopic and mesoscopic models.The stress–strain curves and fracture modes from simulation show good agreement with the experimental curves and fracture morphology.Local interface and matrix damage initiate first under warp directional tension.Thereafter,interfacial failure,weft yarn cracking,and matrix failure occur successively.Axial fracture of warp yarn,which displays a quasi-ductile fracture characteristic,dominates the ultimate composites failure.Under weft directional tension,interfacial failure and warp yarn rupture occur at the early and middle stages.Matrix failure and weft yarn fracture emerge simultaneously at the final stage,leading to the cata-strophic failure of composites.The weft directional strength and fracture strain are lower than the warp directional ones because of the lower weft density and the more serious brittle fracture of weft yarns. | Zhenjun WANG Siyuan YANG Shiping SUN Yingfeng ZHANG Changchun CAI Bowen XIONG Wei YANG Zhifeng XU Huan YU | 2021 | Chinese Journal of Aeronautics2021，34，8： | 4 |
| 5 | An adaptive scaled boundary finite element method by subdividing subdomains for elastodynamic problems显示文摘The scaled boundary finite element method(SBFEM) is a semi-analytical numerical method,which models an analysis domain by a small number of large-sized subdomains and discretises subdomain boundaries only.In a subdomain,all fields of state variables including displacement,stress,velocity and acceleration are semi-analytical,and the kinetic energy,strain energy and energy error are all integrated semi-analytically.These advantages are taken in this study to develop a posteriori h-hierarchical adaptive SBFEM for transient elastodynamic problems using a mesh refinement procedure which subdivides subdomains.Because only a small number of subdomains are subdivided,mesh refinement is very simple and efficient,and mesh mapping to transfer state variables from an old mesh to a new one is also very simple but accurate.Two 2D examples with stress wave propagation were modelled.The results show that the developed method is capable of capturing propagation of steep stress regions and calculating accurate dynamic responses,using only a fraction of degrees of freedom required by adaptive finite element method. | ZHANG ZiHua 1,2,YANG ZhenJun 2,LIU GuoHua 1 & HU YunJin 1 1 College of Civil Engineering and Architecture,Zhejiang University,Hangzhou 310058,China 2 School of Engineering,University of Liverpool,L69 3GQ,UK | 2011 | Science China(Technological Sciences)2011，54，S1： | 4 |
| 6 | Molecular toxicity of earthworms induced by cadmium contaminated soil and biomarkers screening显示文摘Earthworms(Eisenia fetida) were used to study the impact of low-dose cadmium in treated artificial soil(0,0.6,3,6,15,30 mg/kg) and contaminated natural soil(1.46 mg/kg).The changes of earthworms' physiological related gene expressions of metallothionein(MT),annetocin,calreticulin and antimicrobial peptides were detected using real-time PCR after a 70-day incubation period.The results showed that low doses of cadmium could up regulate earthworms' MT and down regulate annetocin gene expression and show a significant positive and negative correlation respectively.The expression of two other genes,calreticulin and anti-microbial peptides,was induced at low doses of cadmium(highest gene expression at 0.6 mg/kg for calreticulin and 6 mg/kg for anti-microbial peptides) and inhibited at high doses.No significant correlation was found for these two genes.This study shows that MT and annetocin genes expression found in earthworms in contaminated soil have the potential to be developed as biomarkers of soil cadmium pollution. | Xiaohui Mo Yuhui Qiao Zhenjun Sun Xiaofei Sun Yang Li | 2012 | Journal of Environmental Sciences2012，24，8： | 4 |
| 7 | Composition and Distributions of Nitrogen and Phosphorus and Assessment of Eutrophication Status in the Maowei Sea显示文摘Maowei Sea(MWS) is the largest oyster maricuture bay in Southwest China. Surface water from 12 sampling sites were collected during the dry season to study the composition and distribution of different forms of nitrogen(N) and phosphorus(P) beginning from the inner bay to the bay mouth in the MWS. An improved multi-parameter eutrophication index was developed and applied for the evaluation of the water quality in the MWS. Dissolved inorganic nitrogen(DIN), dissolved organic nitrogen(DON), and particulate nitrogen(PN) averagely accounted for 11.28%, 65.32%, and 23.39% of total N(TN) pool, dissolved inorganic phosphorus(DIP), dissolved organic phosphorus(DOP), and particulate phosphorus(PP) averagely accounted for 54.58%, 30.31%, and 15.12% of total P(TP) pool, respectively. DON and DIP were respectively the dominant forms of N and P in surface water of the MWS, during the study period. Concentration trends of DIN, DIP, DOP, PN, dissolved silicate(DSi), total organic carbon(TOC), chemical oxygen demand(COD) decreased from the inner bay to the bay mouth, suggesting that the MWS may be largely influenced by land-based inputs. Based on nutrient contents and stoichiometry, it likely that phytoplankton growth in the MWS is strongly limited by DIP during the dry season. Results from the improved eutrophication index revealed that the water quality in the MWS is in a state of moderate to poor eutrophication(average EI = 0.953). The eutrophication state decreased from the inner bay to the bay mouth. Nitrate(NO3-N), DON, DIP, DOP, and DSi showed significant positive correlations with eutrophication index(r2 = 0.52 – 0.78, P < 0.05), implying that these nutrients are among the significant factors, which could be used in evaluating the eutrophication status of the MWS. | LU Dongliang HUANG Xueren YANG Bin DAN Solomon Felix KANG Zhenjun ZHOU Jiaodi LAO Yanling ZHONG Qiuping WU Heng | 2021 | Journal of Ocean University of China2021，20，2： | 3 |
| 8 | Synthesis and Anti-HIV Activity of a Series of 6-Modified 2',3'-Dideoxyguanosine and 2',3'-Didehydro-2',3'- dideoxyguanosine Analogs显示文摘寻找潜在的 2,3-dideoxyguanosine (ddG ) 和 2,3-didehydro-2,3-dideoxyguanosine (D4G ) prodrugs,一系列 6-modified ddG, D4G 类似物在基于房间的试金为他们的 anti-HIV 活动和 cytotoxities 被综合并且评估。所有类似物显示出低 cytotoxicities,他们中的一些显示了良性的 anti-HIV 活动。在 vivo, ddGTP 和 D4TTP 的活跃 triphosphate 形式,被一个新奇、灵巧的“一个壶”也综合方法。由 Taq, Therminater DNA 聚合酶和在 DNA/RNA 海滨合并的 HIV 反向的 transcriptase (RT ) 的 ddGTP 和 D4TTP 的识别被一个非放射性方法调查, Km 是坚定的。 | Lujia Xie Xiantao Yang Delin Pan Yingli Cao Mou Cao Guichun Lin Zhu Guan Ying Guo Lihe Zhang Zhenjun Yang | 2013 | Chinese Journal of Chemistry2013，31，9： | 2 |
| 9 | Application of scaled boundary finite element method in static and dynamic fracture problems显示文摘放大边界有限元素方法(SBFEM ) 是联合两个有限元素方法的优点的一个最近发达的数字方法(女性) 并且边界元素方法(BEM ) 并且与它的自己的特殊特征也。最突出的优点之一从其在裂缝尖端的奇特是经分解的答案代表了的压力直接是它精明的压力紧张因素(SIF ) 的能力。这个优点在这研究被拿为静态、动态的破裂问题建模。为静态的问题,象一样简单的一个重新协调的算法在 BEM 使用当保留概论和灵活性时,被开发女性。混合模式裂缝繁殖的充分自动的建模然后被把重新协调的算法与一个繁殖标准相结合认识到。为动态破裂问题,在频率领域管理方程的 SBFEM 的一个最新发达的增加系列的答案被使用计算动态 SIF。三个飞机问题被建模。数字结果证明 SBFEM 罐头精确地预言静态、动态的 SIF,击碎路径和负担排水量曲线,用仅仅传统的有限元素方法通常需要的自由的很少的度。 | Zhenjun Yang | 2006 | Acta Mechanica Sinica2006，22，3： | 2 |
| 10 | Synthesis and Antitumor Activity Evaluation of γ-Monofluorinated and γγy-Difluorinated Goniothalamin Analogues显示文摘一系列小说, -difluorinated Goniothalamin 类似物 4a4i 和 6a6i 被综合。关键步通过脂肪分解酵素 AK 包括了邻近 gem-difluoromethylene 组的 C-5 stereocenter 的构造催化运动分辨率,经由联合的 Stille 的芳基组的介绍,和由 1,5-oxidative 的 lactonization 环合。这些, -difluorinated Goniothalamin 类似物 4a4i 和他们的 enantiomers 6a6i,和几相应 -monofluorinated Goniothalamin,类似物生物学上与四根不同癌症房间线被作比较。复合 7h 在 micromolar 范围作为父母(R)-Goniothalamin 显示出将近相等的力量。在在 antitumor 活动的 fluoromethylene 和 gem-difluoromethylene 之间的不同氟的符号效果通过生物鉴定数据的分析被讨论。 | Yi Yang Zhenjun Yang Chunru Cheng Fengling Qing | 2013 | Chinese Journal of Chemistry2013，31，6： | 2 |
| 11 | A subunit vaccine based on rH-NS induces protection against Mycobacterium tuberculosis infection by inducing the Thl immune response and activating macrophaqes显示文摘 | Yuan Liu Suting Chen Bowen Pan Zhu Guan Zhenjun Yang Linfei Duan Hong Cai | 2016 | Acta Biochimica et Biophysica Sinica2016，48，10： | 2 |
| 12 | Sericin protects against diabetes-induced injuries in sciatic nerve and related nerve cells显示文摘Sericin from discarded silkworm cocoons of silk reeling has been used in different fields,such as cosmetology,skin care,nutrition,and oncology.The present study established a rat model of type 2 diabetes by consecutive intraperitoneal injections of low-dose (25 mg/kg) streptozotocin.After intragastrical perfusion of sericin for 35 days,blood glucose levels significantly declined,and the expression of neurofilament protein in the sciatic nerve and nerve growth factor in L4-6 spinal ganglion and anterior horn cells significantly increased.However,the expression of neuropeptide Y in spinal ganglion and anterior horn cells significantly decreased in model rats.These findings indicate that sericin protected the sciatic nerve and related nerve cells against injury in a rat type 2 diabetic model by upregulating the expression of neurofilament protein in the sciatic nerve and nerve growth factor in spinal ganglion and anterior horn cells,and downregulating the expression of neuropeptide Y in spinal ganglion and anterior horn cells. | Chengjun Song Zhenjun Yang Meirong Zhong Zhihong Chen | 2013 | Neural Regeneration Research2013，8，6： | 2 |
| 13 | Fully automatic modelling of mixed-mode crack propagation using scaled boundary finite element method 显示文摘 | Yang Zhenjun | 2006 | Engineering Fracture Mechanics2006，73，12： | 1 |
| 14 | Saving energy in the heat pump air conditioning system driven by gas engine 显示文摘 | Xu Zhenjun Yang Zhao | 2009 | Energy andBuildings2009，41，2： | 1 |
| 15 | Saving energy in the heat pump air conditioning system driven by gas engine 显示文摘 | Xu Zhenjun Yang Zhao | 2009 | Energy and Buildings2009，41，2： | 1 |
| 16 | Fatigue behavior of recycled aggregate concrete under compression and bending cyclic loadings 显示文摘 | XIAO Jianzhuang LI Hong YANG Zhenjun | 2013 | Construction and Building Materials2013，38，： | 1 |
| 17 | Polygon scaled boundary finite elements for crack propagation modelling显示文摘 | Ean Tat Ooi Chongmin Song Francis Tin‐Loi Zhenjun Yang | 2012 | Int J Numer Meth Engng2012，，3： | 1 |
| 18 | Fully automatic modelling of mixed-mode crack propagation using scaled boundary finite element method显示文摘 | Zhenjun Yang | 2006 | Engineering Fracture Mechanics2006，，12： | 1 |
| 19 | New fabricate of styrene-butadiene rubber/montmorillonite nanocomposites by anionic polymerization 显示文摘 | Zhang Zhenjun Zhang Lina Li Yang | 2005 | Polymer2005，46，1： | 1 |
| 20 | Estrogen intervention in microvascular morphology and choline acetyltransferase expression in rat hippocampal neurons in chronic cerebral ischemia显示文摘We observed dynamic changes in microvessels and a protective effect of estrogen on chronic cerebral ischemia ovariectomized rat models established through permanent occlusion of bilateral carotid arteries at 7,14 and 21 days.The results revealed that estrogen improved microvasculature in the hippocampus of chronic cerebral ischemic rats,upregulated Bcl-2 protein expression,downregulated Bax protein expression,increased choline acetyltransferase expression in hippocampal cholinergic neurons,and suppressed hippocampal neuronal apoptosis.These findings indicate that estrogen can protect hippocampal neurons in rats with chronic cerebral ischemia. | Zhenjun Yang Hongwei Yan Guomin Zhang Zhihong Chen Jingfeng xue | 2011 | Neural Regeneration Research2011，6，17： | 1 |
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