|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hand self-Shiatsu for sleep problems in p ersons with chronic pain: a pilot study显示文摘OBJECTIVE: Difficulty falling asleep(sleep latency) and staying asleep(sleep maintenance) are common problems for persons living with pain. Research demonstrates that sleep problems are, in turn, related to exacerbation of chronic pain. There is a growing body of evidence for a range of pragmatic, non-pharmacological sleep interventions that can potentially be incorporated into pain management programs. This study looks at the outcome of teaching patients with musculoskeletal pain standardized pre-bedtime hand self-Shiatsu(HSS) to reduce sleep latency. METHODS: A case series design, with participants acting as their own controls, was selected to facilitate hypothesis generation for this novel, under-researched intervention. Sleep efficiency, latency and maintenance, sleep beliefs, pain intensity and basic participant demographics were collected at baseline with actigraphy and standardized self-report questionnaires. After one week of baseline data collection, the HSS intervention was taught to participants. Follow-up data were collected at 2 and 8 weeks post-intervention. RESULTS: Data collected at baseline and the two follow-up periods revealed no apparent changes in the objective actigraphy data. However a trend toward improved self-reported sleep latency(time to fall asleep) and sleep duration(time spent asleep) emerged. A number of participants reported they were more concerned with increasing their period of unbroken sleep as opposed to their total sleep time and it is possible that HSS may be useful to be applied during nighttime awakenings as well as before bed. None of the participants reported adverse effects of the intervention. CONCLUSION: These preliminary findings are promising and future studies exploring the mechanism of action and with stronger control of treatment fidelity are indicated. | Cary A.Brown Geoff Bostick Leisa Bellmore Dilesha Kumanayaka | 2014 | Journal of Integrative Medicine2014，12，2： | 9 |
| 2 | Steroid requirements and immune associations with vitamin D are stronger in children than adults with asthma显示文摘 | Elena Goleva Daniel A. Searing Leisa P. Jackson Brittany N. Richers Donald Y.M. Leung | 2012 | The Journal of Allergy and Clinical Immunology2012，，5： | 1 |
| 3 | Effect of perceived sport event and sponsor image fit on consumers' cognition,affect,and behavioral intentions显示文摘 | Gi-Yong Koo Jerome Quarterman and Leisa Flynn | 2006 | Sport Marketing Quarterly2006，15，2： | 1 |
| 4 | Mother–Child Communication about Sexual Abuse Prevention显示文摘 | Kerryann Walsh Leisa Brandon Lisa Chirio | 2012 | Journal of Child Sexual Abuse2012，，4： | 1 |
| 5 | HPV Determination in the Control After LEEP Due to CIN II-III: Prospective Study and Predictive Model显示文摘 | Pere Fuste Bea Bellosillo Xavier Santamaria Gemma Mancebo Leisa Mari?oso Francesc Alameda Blanca Espinet Francese Sole Sergi Serrano Ramon Carreras | 2009 | International Journal of Gynecological Pathology2009，，2： | 1 |
| 6 | So- matic activation of the K-ras oncogene causes early onset lung cancer in mice显示文摘 | Johnson Leisa Mercer Kim Greenbaum Doron | 2001 | Nature2001，410，6832： | 1 |
| 7 | Immunohistochemical Expression of p16 and Ki-67 Correlates With Degree of Anal Intraepithelial Neoplasia显示文摘 | Sarah M. Bean Isam Eltoum Debra K. Horton Leisa Whitlow David C. Chhieng | 2007 | The American Journal of Surgical Pathology2007，，4： | 1 |
| 8 | Development of a TCR beta repertoire assay for profiling liquid biopsies from NSCLC donors显示文摘Aim:The aim of this study was to demonstrate the utility of T-Cell receptor beta(TCRβ)sequencing as a robust method for assessing T-cell repertoire changes in donors with non-small cell lung cancer(NSCLC).We further demonstrated the use of the assay by monitoring repertoire modulation in a defined model antigen system,cytomegalovirus(CMV).Methods:Peripheral blood mononuclear cells from four healthy donors were challenged with a 1-week exposure to whole-cell lysate from CMV-infected cells or CMVpp65495-503 peptide(NLVPMVATV).T-cell repertoire perturbations were assessed using the Oncomine TCR Beta-SR Assay and Ion GeneStudio S5 Plus Sequencer.A pp65 tetramer flow cytometry assay was used as an orthogonal method to assess clonal expansion of a subset of CMV-specific T-cells.For evaluation of the assay in peripheral blood lymphocytes from NSCLC donors,five whole blood specimens were evaluated using the same sequencing workflow.Results:The TCR beta assay identified 6,683-61,936 unique clones from 1-2 million reads per sample,and an average of 80%of the total reads were usable for TCR profiling.In the NSCLC donors,TCR convergence and clonality values were consistent with published results and ranged 0.016-0.033 for convergence and 0.09-0.48 for clonality.In the CMV study,TCR sequencing detected the expansion of a common family of clones in all 4 samples in response to antigen stimulation.This expansion corresponded to an increase in pp65 tetramer staining by flow cytometry.Baseline TCR convergence scores ranged 0.009-0.041 and increased 5-fold in one sample as a result of pp65 antigen stimulation.Conclusion:The results of this study demonstrated the utility of profiling of the TCRβrepertoire in a model system and in donors with NSCLC.Additionally,we demonstrated the correlation between RNA-seq methods and protein-tetramer analysis using flow cytometry.These techniques represent an emerging solution that could complement other liquid and tissue diagnostic assays in the clinic and will be of value in predicting host response/resistance and adverse events to immunotherapies.Prospective clinical studies are on-going in which the developed TCR beta assay will undergo further validation。 | Leisa P.Jackson Benjamin A.Tjoa Hestia Mellert Gary A.Pestano | 2020 | Cancer Drug Resistance2020，3，3： | 1 |
| 9 | Tumor necrosis factor a enhances Oocyte/Follicle apoptosis in the neonatal rat ovary显示文摘 | LEISA J MORRISON JENNIFER L MARCINKIEWICZ | 2002 | Biology of Reproduction2002，66，： | 1 |
| 10 | Changes in language development among autistic and peer children in segregated and integrated preschool settings显示文摘 | Sandra L. Harris Jan S. Handleman Barbara Kristoff Leisa Bass Rita Gordon | 1990 | Journal of Autism and Developmental Disorders1990，，1： | 1 |
| 11 | Effect of percieived sport event and sponsor image fit on consumers' cognition, affect, and behavioral intentions 显示文摘 | GIYONG K QUARTERMAN JEROME FLYNN LEISA | 2006 | Sport Mark Q2006，15，2： | 1 |
| 12 | Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity显示文摘 | Clodagh CO Leisa J Bridget B | 2004 | Cancer Cell2004，6，11： | 1 |
| 13 | The effects of work control and job demands on employee adjustment and work performance 显示文摘 | Leisa D S Deborah J T | 1998 | Journal of Occupational and Organizational Psychology1998，71，： | 1 |
| 14 | Late Cenomanian to middle Turonian high-resolution carbon isotope stratigra- phy: New data from the Munsterland Cretaceous Basin, Germany显示文摘 | Voigt S Auraga A Leisa F | 2007 | Earth Planetary Science Letters2007，253，： | 1 |
| 15 | Opinion leaders and opinion seekers: Two new measurement scales显示文摘 | Leisa Reinecke Flynn Ronald E. Goldsmith Jacqueline K. Eastman | 1996 | Journal of the Academy of Marketing Science1996，，2： | 1 |
| 16 | Effect of Perceived Sport Event and Sponsor Image Fit on Consumers' Cognition, Affect, and Behavioral Intentions显示文摘 | Gi- Yong Koo Jerome Quarterman and Leisa Flynn | 2006 | Sport Marheting Quarterly2006，15，： | 1 |
| 17 | 1997-2006年间旅行返乡的登革热患者的特征及其发病的季节性和年度趋势显示文摘 | Eli Schwartz Leisa H Weld Annelies Wilder-Smith 叶莺 林春芳 | 2008 | 中国人兽共患病学报2008，，09： | 1 |
| 18 | Australia, the United States and a ’China growing strong’: managing conflict avoidance显示文摘 | William T. Tow Leisa Hay | 2001 | Australian Journal of International Affairs2001，，1： | 1 |
| 19 | The effects of work control and job demands on employee adjustment and work performance 显示文摘 | Leisa D S Deborah J T | 1998 | Journal of Occupational and Organizational Psychology1998，71，： | 1 |
| 20 | Discussion:Food security and sustainable food systems:The role of soil显示文摘Editorial notes This discussion is edited from a dialogue session of‘3rd Global Soil Week 2015'(globalsoilweek.org).The‘Global Soil Week'(GSW)is a multi-stakeholder platform of high-level policy-makers,scientists,NGOs,CSOs,farmers,artists,international organizations,and the private sector.One of the main purposes of the GSW is to raise public awareness of the issues of soil and land.The‘Global Soil Week'advocates soil management in the context of sustainable development and promote equitable access to land.The‘3rd Global Soil Week 2015'was held from 19 to 23 April 2014 in Berlin.The session,on April 202015,2015,discussed the topic of‘Food Security and Sustainable Food System:the Role of Soil'. | Matheus Alves Zanella Maryam Rahmanian Leisa Nicola Perch Carolin Callenius JoséLuis Rubio Faustin Vuningoma Stephan Rist Paul Mapfumo | 2015 | International Soil and Water Conservation Research2015，3，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员