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| 1 | Cultured meat from muscle stem cells: A review of challenges and prospects显示文摘Growing muscle tissue in culture from animal stem cells to produce meat theoretically eliminates the need to sacrifice animals. So-called 'cultured' or 'synthetic' or 'in vitro' meat could in theory be constructed with different characteristics and be produced faster and more efficiently than traditional meat. The technique to generate cultured muscle tissues from stem cells was described long ago, but has not yet been developed for the commercial production of cultured meat products. The technology is at an early stage and prerequisites of implementation include a reasonably high level of consumer acceptance, and the development of commercially-viable means of large scale production. Recent advancements in tissue culture techniques suggest that production may be economically feasible, provided it has physical properties in terms of colour, flavour, aroma, texture and palatability that are comparable to conventional meat. Although considerable progress has been made during recent years, important issues remain to be resolved, including the characterization of social and ethical constraints, the fine-tuning of culture conditions, and the development of culture media that are cost-effective and free of animal products. Consumer acceptance and confidence in in vitro produced cultured meat might be a significant impediment that hinders the marketing process. | Isam T Kadim Osman Mahgoub Senan Baqir Bernard Faye Roger Purchas | 2015 | Journal of Integrative Agriculture2015，14，2： | 20 |
| 2 | DICER-LIKE3 Activity in Physcomitrella patens DICER-LIKE4 Mutants Causes Severe Developmental Dysfunction and Sterility显示文摘交易的小介入 RNA (ta-siRNAs ) 是在 microRNA 依赖的劈开,进双 stranded RNA 的变换,和骰子依赖者分阶段执行处理以后,免除 TAS 先锋抄本的植物特定的 siRNAs。象 microRNAs (miRNAs ) 一样, ta-siRNAs 在广泛的补充的地点的目标 RNA 的直接地点特定的劈开。这里,我们证明像骰子 Physcomitrella 圣餐盘(PpDCL4 ) 的 4 蛋白质为 21 核苷酸(nt ) 的生物的续生说是必要的 ta-siRNAs。在 PpDCL4 异种,离开缩放 23 并且 24-nt ta-siRNAs 作为 PpDCL3 的结果积累了活动。PpDCL4 异种在整个 Physcomitrella 开发显示严重畸形,包括绝育,那充分在 PpDCL3/PpDCL4 双异种植物被颠倒。因此, PpDCL3 活动,不是 PpDCL4 功能本身的损失,是 PpDCL4 显型的原因。另外,我们描述几新 Physcomitrella 交易 siRNA loci,其三属于一个新家庭, TAS6。TAS6 loci 被切的 miR156 和 miR529 目标地点代表并且在到 PpTAS3 loci 的靠近的最近。 | M. Asif Arif Isam Fattash Zhaorong Ma Sung Hyun Cho Anna K. Beike Ralf Reski Michael J. Axtell Wolfgang Frank | 2012 | Molecular Plant2012，5，6： | 4 |
| 3 | 法国里尔大学校园智能供水系统应用研究显示文摘管网渗漏是城市供水系统普遍面临的挑战。以欧洲智能供水系统示范项目(Smart Water 4Europe)——法国里尔大学校园为例,介绍了其实施的智能供水系统平台及其在渗漏检测和控制方面的应用情况,并讨论了水量平衡法(WBM)、流量分布模式比较法(CFPDM)和最小夜间流量法(MNFM)在渗漏检测方面的应用。实践表明,智能供水系统在法国里尔大学校园管网漏损控制中的应用是成功的。 | Isam Shahrour 谢雄耀 卞汉兵 Elias Farah | 2018 | 给水排水2018，44，9： | 3 |
| 4 | Laboratory Study of Geotextiles Performance on Reinforced Sandy Soil显示文摘This paper presents the results of triaxial tests conducted for the investigation of the influence of geotextiles on stress-strain and volumetric change behaviour of reinforced sandy soil. Tests were carried out on loose sandy soil. The experimental program includes drained compression tests on samples reinforced with different values of both geotextiles layers(Ng) and confining pressure(σ′c). Two methods of preparation were used: air pluviation(AP) and moist tamping(MT). Test results show that the geotextiles induce a quasi-linear increase in the stress deviator(q) and volume contraction in the reinforced sand. Method of preparation significantly affects the shear strength; samples prepared by the air pluviation method and mobilized deviator stresses are significantly higher than those prepared by moist tamping method. Geotextiles restrict the dilation of reinforced sandy soil and consequently the contraction increases. The mobilized friction angle increases with increasing number of layers and decreases with increasing initial confining pressure. Samples prepared by moist tamping present mobilized friction angles significantly lower than those prepared by air pluviation method. For samples prepared by the air pluviation method, the secant modulus at ε1=1% and 5% decreases with increasing geotextile layers; those prepared by the moist tamping method, secant modulus at ε1=1% and 5% increases with increasing number of geotextile layer sand confining pressure. From 10% axial strain, secant modulus increases with increasing inclusions of geotextile layers. | Brahim Abdelkader Arab Ahmed Belkhatir Mostefa Shahrour Isam | 2016 | Journal of Earth Science2016，27，6： | 2 |
| 5 | Use of soft computing techniques for tunneling optimization of tunnel boring machines显示文摘Thanks to advances in tunnel boring machine(TBM)and monitoring,significant progress has been achieved in the application of soft computing techniques for the optimization of TBM tunneling and the reduction of disturbance related to tunneling in urban areas.Because experimental,analytical,and numerical methods have limitations in solving problems related to TBM tunneling,engineers can use soft computing techniques in analyzing the relationship between the target tunneling responses and influential design inputs parameters,including the geometrical,geological,and TBM operational factors.These techniques are useful in achieving robust and low-cost solutions.However,engineers face difficulties in making an optimal choice of the soft computing technique to solve the complex problems related to TBM tunneling.To help with this choice,this study presents state of the art about the use of soft computing techniques in TBM tunneling through practical applications.The study proposes recommendations for the optimal use of these techniques,in particular(i)the importance of preliminary analyses for the selection and reduction of input parameters,(ii)the necessity to complete insufficient data using laboratory tests and numerical modeling,(iii)the selection of reduced number of hidden layers and nodes to avoid overfitting,(iv)the use of recurrent neural networks to deal with time-series data,and(v)the association of soft computing methods with hybrid optimization techniques to reduce the risk of convergence to local minima. | Isam Shahrour Wengang Zhang | 2021 | Underground Space2021，6，3： | 2 |
| 6 | Self-reported Taste and Smell Disorders in Patients with COVID-19:Distinct Features in China显示文摘Last December 2019,a cluster of viral pneumonia cases identified as coronavirus disease 2019(COVID-19)was reported in Wuhan,China.We aimed to explore the frequencies of nasal symptoms in patients with COVID-19,including loss of smell and taste,as well as their presentation as the first symptom of the disease and their association with the severity of COVID-19.In this retrospective study,1206 laboratory-confirmed COVID-19 patients were included and followed up by telephone one month after discharged from Tongji Hospital,Wuhan.Demographic data,laboratory values,comorbidities,symptoms,and numerical rating scale scores(0–10)of nasal symptoms were extracted from the hospital medical records,and confirmed or reevaluated by the telephone follow-up.From patients(n=1172)completing follow-up,199(17%)subjects had severe COVID-19 and 342(29.2%)reported nasal symptoms.20.6%COVID-19 patients had loss of taste(median score=6),while 11.4%had loss of smell(median score=5).Loss of taste scores,but not loss of smell scores,were significantly increased in severe vs.nonsevere COVID-19 patients.Interleukin(IL)-6 and lactose dehydrogenase(LDH)serum levels were positively correlated with loss of taste scores.About 80%of COVID-19 patients recovered from smell and taste dysfunction in 2 weeks.In this cohort,only 1 out of 10 hospital admitted patients had loss of smell while 1 out of 5 reported loss of taste which was associated to severity of COVID-19.Most patients recovered smell and taste dysfunctions in 2 weeks. | Jia SONG Yi-ke DENG Hai WANG Zhi-chao WANG Bo LIAO Jin MA Chao HE Li PAN Yang LIU Isam Alobid De-yun WANG Ming ZENG Joaquim Mullol Zheng LIU | 2021 | Current Medical Science2021，41，1： | 2 |
| 7 | CIGS solar cell with MBE-grown ZnS buffer layer 显示文摘 | Islam M M Isam S | 2009 | Solar Energy Mater Solar Cells2009，93，： | 1 |
| 8 | Energy and exergy analysis of steam power plant in Jordan显示文摘 | Isam H.Aljundi | | 0，，： | 1 |
| 9 | Immunohistochemical Expression of P16 and Ki-67 Correlates With Degree of Anal Intraepithelial Neoplasia显示文摘 | SARAH M B ISAM E DEBRA K | 2007 | Am J Surg Pathol2007，31，4： | 1 |
| 10 | Comparative study of rock slope stability analysis methods for hydropower projects显示文摘 | Chen Sheng-hong Qing Wei-xin Shahrour Isam | 2007 | Mechanics Research Communications2007，34，1： | 1 |
| 11 | A prospective trial of intravenous streptokinase in acute myocardal infarction(ISAM): mortality, morbidity and infarct size at 21 days 显示文摘 | The ISAM study Group | 1988 | N Engl J Med1988，314，： | 1 |
| 12 | Effect of dry hydrocarbons and critical point temperature on the efficiencies of organic Rankine cycle 显示文摘 | Aljundi Isam H | 2011 | Renewable Energy2011，36，4： | 1 |
| 13 | CFD Analysis of the Effects of Co-firing Biomass with Coal显示文摘 | Ghenai Chaouki Janajreh Isam | | 0，，08： | 1 |
| 14 | The eyestalk androgenic gland testis endocrine axis in the crayfish Cherax quadricarinatus显示文摘 | Isam Khalaila Rivka Manor Simy Weil | 2002 | General and Comparative Endocrinology2002，，127： | 1 |
| 15 | Early complications after one hundred and forty-four consercutive hip revisions with impacted morselized allograft bone and cement显示文摘 | Ewald O Isam A | 2002 | J Bone Joint Surg(AM)2002，84，8： | 1 |
| 16 | Effects of implantation of hypertrophied androgenic glands on sexual characters and physiology of the reproductive system in the female red claw crayfish,Cherax quadricarinatus显示文摘 | Isam K Tal K Uri A | 2001 | General and Comparative Endocrinology2001，，121： | 1 |
| 17 | Determination of loratadine in human plasma by liquid chromatography electrospray ionization ion-trap tandem mass spectrometry显示文摘 | Isam Ismail Salem Jafer Idrees Jaafar I Al Tamimi | 2004 | Journal of Pharmaceutical and Biomedical Analysis2004，34，： | 1 |
| 18 | Multicomponent corrosion inhibitor system for recirculating cooling water systems/based on nitrite, molybdate, and inorganic phosphorate显示文摘 | Borno A Isam M Khraishi M | 1989 | Corrosion1989，45，12： | 1 |
| 19 | Use of Artificial Neural Network Simulation Metamodelling to Assess Groundwater Contamination in a Road Projuct显示文摘 | Laurent L Isam S | 2007 | Mathematical and Computer Modelling2007，，4： | 1 |
| 20 | Genetic relationships and reproductive isolation mechanism among the Fejervarya limnocharis complex from Indonesia(Java)and other Asian countries显示文摘 | Djong H.T Isam M.M Nishioka M Matsui M Ota H Kuramoto M Khan M.M.R Alam M.S De Silva A Khonsue W Sumida M | | 0，，： | 1 |
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