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1Fluid Inclusions of Calcite and Sources of Ore-forming Fluids in the Huize Zn-Pb-(Ag-Ge) District, Yunnan, China显示文摘The Huize Zn-Pb- (Ag-Ge) district is a typical representative of the well-known medium-to large-sized carbonate-hosted Zn-Pb- (Ag-Ge) deposits, occurring in the Sichuan-Yunnan-Guizhou Pb-Zn Ore-forming Zone.Generally, fluid inclusions within calcite, one of the major gangue minerals, are dominated by two kinds of small (1-10μm) inclusions including pure-liquid and liquid. The inclusions exist in concentrated groups along the crystal planes of the calcite. The ore-forming fluids containing Pb and Zn, which belong to the Na+-K+-Ca2+-C1--F--SO42- type, are characterized by temperatures of 164-221 ℃, medium salinity in 5-10.8 wt% NaCl, and medium pressure at 410xl0s to 661 x 10s Pa. The contents of Na+-K+ and Cl--F-, and ratios of Na+/K+-Cl-/F- in fluid inclusions present good linearity. The ratios of Na+/K+ (4.66-6.71) and C1-/F- (1 8.21-31.04) in the fluid inclusions of calcite are relatively high, while those of Na+/K+ (0.29-5.69) and Cl-/F- (5.00-26.0) in the inclusions of sphalerite and pyrite are relatively low. The ratio of Na+/K+increases in accord with those of C1-/F, which indicates that ore-forming fluid of deep source participates in the mineralization. The waters of fluid inclusions have δD values from -43.5‰ to -55.4‰ of calcite. The δ18Ov-sMow values of the ore-forming fluids, calculated values, range from 17.09‰ to 18.56‰ of calcite and 17.80‰ to 23.14‰ for dolomite.δ13 Cv-PDB values range from -1.94‰ to -3.31‰ for calcite and -3.35‰ to 0.85‰ for the ore-bearing dolomite. These data better demonstrate that the ore-forming fluids were mainly derived from metamorphic water and magmatic hot fluid, in relation to the metamorphism of the Kunyang Group in the basement and magmatic hydrothermalism. The deposit itself might have resulted from ascending cycles of ore-forming fluid, enriched in Pb and Zn. The Huize Zn-Pb- (Ag-Ge)deposits related to carbonate-hosted Zn-Pb sulphides.HANRunsheng LILTCongqiang HUANGZhilong MADeyun LIYuan HUBin MAGengsheng LEILi 2004Acta Geologica Sinica(English Edition)2004,78,2:24
2Efficacy of topical chamomile on the incidence of phlebitis due to an amiodarone infusion in coronary care patients:a double-blind,randomized controlled trial显示文摘BACKGROUND:Amiodarone is a useful antiarrhythmic drug.Phlebitis,caused by intravenous amiodarone,is common in patients in coronary care units(CCUs).OBJECTIVE:The aim of this study was to evaluate the effect of topical chamomile on the incidence of phlebitis due to the administration of an amiodarone infusion into the peripheral vein.DESIGN,SETTING,PARTICIPANTS AND INTERVENTIONS:This was a randomized,double-blind clinical trial,conducted on 40 patients(n=20 per group)in two groups—an intervention group(chamomile ointment)and a control group(lanoline,as a placebo),hospitalized in the CCUs and undergoing an amiodarone infusion into the peripheral vein over 24 h.Following the cannulation and commencement of the infusion,placebo or chamomile ointment was rubbed in,up to 10 cm superior to the catheter and repeated every eight hours for three days.The cannula site was then assessed based on the phlebitis checklist.MAIN OUTCOME MEASURES:The incidence and time of occurrence of phlebitis,relative risk,severity of phlebitis were the main outcome measures.RESULTS:Nineteen patients(19/20)in the control group had phlebitis on the first day of the study and one patient(20/20)on the second day.In the intervention group,phlebitis occurred in 13 cases(13/20)on the first day and another two(2/7)was found on the second day.The incidence of phlebitis was significantly different between two groups(P=0.023).The cumulative incidence of phlebitis in the intervention group(15/20)is significantly later and lower than that in the control group(20/20)during two days(P=0.008).Two patients in the intervention group did not develop phlebitis at all during the 3-day study.Also,the relative risk of phlebitis in the two groups was 0.68(P=0.008 5).A significant difference was not observed with regard to phlebitis severity in both groups.CONCLUSION:It seems that phlebitis occurred to a lesser extent and at a later time frame in the intervention group compared to control group.Topical chamomile may be effective in decreasing the incidence of phlebitis due to an amiodarone infusion.Maryam Sharifi-Ardani Leili Yekefallah Saeed Asefzadeh Marjan Nassiri-Asl 2017Journal of Integrative Medicine2017,15,5:9
3Hepatocyte-like cells from directed differentiation of mouse bone marrow cells in vitro显示文摘Aim: To design the effective directed differentiation medium to differentiate bone marrow cells into hepatocyte-like cells. Methods: Bone marrow cells were cultured in the directed differentiation media including fibroblast growth factor-4 (FGF-4) and oncostatin M (OSM). Hepatocyte-like cells from directed differentiation of bone marrow cells were identified through cell morphology, RNA expressions by reverse transcriptase-polymerase chain reaction (RT-PCR), protein expressions by Western blot, and hepatocellular synthesis and metabolism functions by albumin ELISA, Periodic acid-Shift staining and urea assay. Results: Some epithelial-like cells or polygonal cells appeared and increased in the course of the cell directed differentiation. Hepatocyte nucleur factor-3β(HNF-3β), albumin (ALB), cytokeratin 18 (CK18), transthyretin (TTR), glucose-6-phosphate (G-6-Pase), and tyrosine aminotransferase (TAT) mRNA were expressed in the course of the directed differentiation. The directed differentiated cells on d 21 expressed HNF-3β, ALB, and CK18 proteins. The directed differentiated cells produced albumin and synthesized urea in a time-dependent manner. They could also synthesize glycogen. Conclusion: Our differentiation media, including FGF-4 and OSM, are effective to differentiate bone marrow cells into hepatocyte-like cells, which could be used for hepatocyte resources for bioartificial liver or hepatocyte transplantation.Xiao-leiSHI Yu-dongQIU QiangLI TingXIE Zhang-huaZHU Lei-leiCHEN LeiLI Yi-taoDING 2005Acta Pharmacologica Sinica2005,26,4:8
4Transfection of promyelocytic leukemia in retrovirus vector inhibits growth of human bladder cancer cells显示文摘Aim: To construct a recombinant retrovirus vector carrying human promyelocytic leukemia (PML) cDNA and identify its expression and biology role in bladder cancer UM-UC-2 cells for future gene therapy. Methods: PML full-length cDNA was inserted into the EcoR Ⅰ and BamH Ⅰ site of pLXSN vector containing the long terminal repeat (LTR) promoter. The vector was identified by restriction enzyme digestion and then transfected into PA317 packaging cell line by calcium phosphate coprecipitation. PML cDNA was detected by polymerase chain reaction (PCR) and the protein was identified by laser confocal microscopy and Western blot in bladder cancer cells, respectively. The morphology was observed by inverted phase contrast microscope, and MTF assay determined growth curve of the bladder cancer cells. Results: Restriction enzyme digestion proved that a 2.1kb PML cDNA was inserted into the pLXSN vector. PCR assay demonstrated that 304 bp fragments were found in UM-UC-2/pLPMLSN transfects. Laser confocal microscopy showed speck dots fluorescence in the UM-UC-2/pLPMLSN nucleus.A 90 kD specific brand was found by Western blot. MTT assay demonstrated the UM-UC-2/pLPMLSN bladder cancer growth inhibition. Conclusion: The retrovirus pLPMLSN vector was successfully constructed and could generate high effective expression of human PML in bladder cancer cell UM-UC-2, suggesting that PML recombinant retrovirus have potential utility in the gene therapy for bladder cancer.LeiLI Da-linHE 2005Acta Pharmacologica Sinica2005,26,5:5
5Preoperative evaluation of pancreaticobiliary tumor using MR multi-imaging techniques显示文摘AIM: To evaluate the clinical value of MR multi-imaging techniques in diagnosing and preoperative assessment of pancreaticobiliary tumor.METHODS: MR multi-imaging techniques, including MR cross-sectional imaging, MR cholangiopancreatography (MRCP) and 3D dynamic contrast-enhanced MR angiography (3D DCE MRA), were performed to make prospective diagnosis and preoperative evaluation in 28 patients with suspected pancreaticobiliary tumors. There were 17 cases of pancreatic adenocarcinoma, 8 cases of biliary system carcinoma and 3 cases of non-neoplastic lesions.RESULTS: Using MR multi-imaging techniques, the accuracy in diagnosing the patients with pancreaticobiliary tumors was 89.3% (25/28). The accuracy in detecting the range of tumor invasion was 80.3% (57/71). The sensitivity, specificity, accuracy, positive and negative predictive value of MR multi-imaging techniques in preoperative assessment of the resectability of pancreaticobiliary tumor were 83.3%, 89.5%, 88.0%, 71.4%, and 94.4%, respectively. There was well diagnostic consistency between MRmulti-imaging techniques and CT (κ = 0.64, P<0.01). The fusion image could be made from MRCP and 3D DCE MRA images.CONCLUSION: MR multi-imaging techniques can integrate the advantages of various MR images. The non-invasive 'all-in-one' MR imaging protocol is the efficient method in diagnosing, staging and preoperative assessment of pancreaticobiliary tumor.LiangZhong LeiLi Qiu-YingYao 2005World Journal of Gastroenterology2005,11,24:3
6Calculation of Phase Equilibria Based on the Levenberg-Marquardt Method显示文摘The Levenberg-Marquardt method, the best algorithm to obtain the least-square solution of nonlinear equations, is applied to calculate the stable phase equilibria. It can get the best combination between robustness and speed of the calculations. Its application to ternary Al-Si-Mg system is executed in detail. The calculated phase equilibria agree well with the experimental results. Furthermore, the Levenberg-Marquardt method is not sensitive to the initial values.RuiiieZHANG LeiLI ZhongweiCHEN ZhiHE WanqiJIE 2005Journal of Materials Science & Technology2005,21,1:3
7A Modified Sensitive Driving Cellular Automaton Model显示文摘A modified cellular automaton model for traffic flow on highway is proposed with a novel concept about the variable security gap. The concept is first introduced into the original Nagel-Schreckenberg model, which is called the non-sensitive driving cellular automaton model. And then it is incorporated with a sensitive driving NaSch model,in which the randomization brake is arranged before the deterministic deceleration. A parameter related to the variable security gap is determined through simulation. Comparison of the simulation results indicates that the variable security gap has different influence on the two models. The fundamental diagram obtained by simulation with the modified sensitive driving NaSch model shows that the maximumflow are in good agreement with the observed data, indicating that the presented model is more reasonable and realistic.GEHong-Xia DAIShi-Qiang DONGLi-Yun LEILi 2005Communications in Theoretical Physics2005,43,2:3
8Liquid-liquid Extraction System Based on Non-ionic Surfactant-salt-H_2O and Mechanism of Drug Extraction显示文摘Extraction behavior of chlorpromazine hydrochloride (CPZ) and procaine hydro- chloride (PCN) in the system described in the title was studied. Research shows that the extraction efficiency of CPZ can amount to 96% by twice extraction, while that of PCN is 77%. This system produces the distribution coefficients (KD) of 12.3 and 2.6 respectively for CPZ and PCN. Extraction mechanism is deduced according to ultraviolet and molecular fluorescence spectra variation of the drugs in the system studied.LeiLI FengLIU2002Chinese Chemical Letters2002,13,4:3
9Competing Risks Data Analysis with High-dimensional Covariates:An Application in Bladder Cancer显示文摘Analysis of microarray data is associated with the methodological problems of high dimension and small sample size. Various methods have been used for variable selection in highdimension and small sample size cases with a single survival endpoint. However, little effort has been directed toward addressing competing risks where there is more than one failure risks. This study compared three typical variable selection techniques including Lasso, elastic net, and likelihood-based boosting for high-dimensional time-to-event data with competing risks. The performance of these methods was evaluated via a simulation study by analyzing a real dataset related to bladder cancer patients using time-dependent receiver operator characteristic(ROC) curve and bootstrap.632+ prediction error curves. The elastic net penalization method was shown to outperform Lasso and boosting. Based on the elastic net, 33 genes out of 1381 genes related to bladder cancer were selected. By fitting to the Fine and Gray model, eight genes were highly significant(P < 0.001). Among them, expression of RTN4, SON, IGF1 R, SNRPE, PTGR1, PLEK, and ETFDH was associated with a decrease in survival time, whereas SMARCAD1 expression was associated with an increase in survival time. This study indicates that the elastic net has a higher capacity than the Lasso and boosting for the prediction of survival time in bladder cancer patients.Moreover, genes selected by all methods improved the predictive power of the model based on only clinical variables, indicating the value of information contained in the microarray features.Leili Tapak Massoud Saidijam Majid Sadeghifar Jalal Poorolajal Hossein Mahjub 2015Genomics, Proteomics & Bioinformatics2015,13,3:2
10Synthesis and characterization of a new compound bearing ketone and hydroxyl groups for preparation of ambient temperature self- crossIinking waterborne polyurethanes 显示文摘Xiaoli Zhu Qingsi Zhang Leili Liu 2007Progress in Organic Coatings2007,59,4:1
11A high-performance liquid chromatographic method for simultaneous determination of21 free amino acids in tea显示文摘Zhao Ming Ma Yan Dai Leili 2013Food Anal Method2013,6,1:1
12Effective factors on linguistic disorder during acute phase following traumatic brain injury in adults显示文摘Chabok S Y Kapourchali S R Leili E K 2012Neuropsychologia2012,50,7:1
13Occurrence of anti- Toxoplasma gondii antibodies in female cattle in south-west of Iran显示文摘Hossein Hamidinejat Masoud Ghorbanpour Leily Nabavi Mohammad Rahim Haji Hajikolaie Mohammad Hossein Razi Jalali 2010Tropical Animal Health and Production2010,,5:1
14显示文摘Zhu Xiaoli Zhang Qingsi Liu Leili 2007Progress in Organic Coatings2007,,59:1
15Rapid synthesis of mesoporous ceria-zirconia solid solutions via a novel salt-assisted combustion process 显示文摘Chen Weifan Li Fengsheng Yu Jiyi Liu Leili Gao Hailian 2006Materials Research Bulletin2006,41,12:1
16Fusaric acid induces apoptosis in saffron root-tip cells: roles of caspase-like activity, cytochrome c, and H2O2显示文摘Leili Samadi Behrooz Shahsavan Behboodi 2006Planta2006,,1:1
17Influence of natural clinoptilolite nanoparticles on thermal stability, scratch resistance and adherence properties of Acrylonitrile butadiene styrene (ABS)显示文摘Ali Olad Leili Ranjbarian 2013Fibers and Polymers2013,,3:1
18A New Algorithm of Data Process in Infrared Search and Track(IRST)System显示文摘Leili Hu Yuqing Chen 2000Proceeding of the 25^th International Conference on Infrared and Millimeter Waves IEEE2000,,:1
19Discovery of Three Variable Stars in Direction toward NGC 4565显示文摘We present the results of a variable star search in a field next to the edgeon galaxies NGC 4565 from the archive data of Beijing-Arizona-Taibei-Connecticut Multicolor Sky Survey. Three new variable stars were discovered. Based on spectra obtained from the 2.16 m NAOC telescope, we identify two of these as RR Lyr stars and one as a special T Tauri star.LeiLi HongWu Xiao-BinZhang Ya-BoWu XuZhou Zhao-JiJiang JunMa 2004Chinese Journal of Astronomy and Astrophysics2004,4,5:1
20A dynamic framework for integrated management of all types of resources in P2P systems显示文摘Mohsen Sharifi Seyedeh Leili Mirtaheri 0,,02:1
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