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| 1 | Antibacterial activity and characterization of secondary metabolites isolated from mangrove plant Avicennia officinalis显示文摘Objective:To explore antibacterial activity and characterization of secondary metabolites isolated from mangrove plant Avicennia officinalis(A.officinalis).Methods:In the present study the leaf extracts of A.officinalis were examined for its antibacterial potential using five different solvents against some reference strains of human pathogenic bacteria for the crude extract.Maximum activity was observed for ethyl acetate and hence different concentrations like 15μL,25μL,and 50μL of ethyl extracts was checked for its antibacterial activity.Partial purification of crude extract was carried by column chromatography and fractions were analyzed using gas chromatography-mass spectrometry(GC-MS) to identify compounds.Results:The crude ethyl acetate extracts of A.officinalis showed remarkable antibacterial activity with zones of inhibition of 13 mm against Eschericia coli(E.coli) and 11 mm against Staphylococcus aureus (S.aureus).Fraction 13(ethyl acetate:methanol= 8:2) as the most potent one against with the minimal inhibitory concentration of 30 mm against E.coli and 25 mm against S.aureus.The GCMS resultsof active column fraction(F13) revealed that the active principals were a mixture of hydroxy- 4 methoxybenzoic acid,diethyl phthalate,oleic acid.Conclusions:The leaf extracts with proven antibacterial effects can clearly be directed towards cancer treatment as to inhibiting cancer cell growth.The limited number of test organisms owes to a constraint of resource.So,the effect of strong bursts of leaf extracts on human pathogenic bacteria should further be tested on a wide range of test organisms. | Valentin Bhimba B J Meenupriya Elsa Lycias Joel D Edaya Naveena Suman kumar M Thangaraj | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，7： | 13 |
| 2 | IL 28 B genotype is not useful for predicting treatment outcome in A sian chronic hepatitis B patients treated with pegylated interferon‐α显示文摘 | Jacinta A Holmes Tin Nguyen Dilip Ratnam Neel M Heerasing Jane V Tehan Sara Bonanzinga Anouk Dev Sally Bell Stephen Pianko Robert Chen Kumar Visvanathan Rachel Hammond David Iser Ferry Rusli William Sievert Paul V Desmond D Scott Bowden Alexander J Thomps | 2013 | J Gastroenterol Hepatol2013，，5： | 2 |
| 3 | A comparison of seven soil P tests for plant species with different external P requirements grown on soils containing rock phosphate and superphosphate residues 显示文摘 | KUMAR V GILKES R J BOLLAND M D A | 1993 | Fertiliser Research1993，33，： | 1 |
| 4 | Preparation,characterization,and tabletting properties of a new cellulose-based pharmaceutical aid显示文摘 | KUMAR V DE-LA-LUZ-REUS-MEDINA M YANG D | 2002 | Int J Pharm2002，235，12： | 1 |
| 5 | Efficient and convenient polyethylene glyeol(PEG)-mediated synthesis of spiro-oxindoles显示文摘 | Meshram H M Kumar D A Prasad B R V | 2010 | Helvetica Chimica ACTA2010，93，4： | 1 |
| 6 | MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods 显示文摘 | Tamura K Peterson D Peterson N Stecher G Nei M Kumar S | 2011 | Molecular Biology and Evolution2011，28，10： | 1 |
| 7 | Phytoremediation:anovel strategy for the removal of toxic metals from the environment using plants显示文摘 | SALT D E BLAYLOCK M KUMAR N P B A | 1995 | Nature Biotechnology1995，13，5： | 1 |
| 8 | Target- ed abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer 显示文摘 | Shrimali D Shanmugam M K Kumar A P | 2013 | Cancer Letters2013，341，2： | 1 |
| 9 | MEGA5 : Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods 显示文摘 | Tamura K Peterson D Peterson N Stecher G Nei M Kumar S | 2011 | Molecular Biology and Evolution2011，28，： | 1 |
| 10 | Characterization of a virion occlusion-defective Autographa californica multiple nucleopolyhedrovirus mutant lacking the p26,p10and p74genes显示文摘 | Wang L Salem T Z Campbell D J Turney C M Kumar C M Cheng X W | 2009 | J Gen Virol2009，90，7： | 1 |
| 11 | Asymptomatic bacteriuria is an independent predictor of urinary tract infections in an ambulatory cirrhotic population:a prospective evaluation显示文摘 | Ye C Kumar D Carbonneau M | 2014 | LiverInt2014，4，6： | 1 |
| 12 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013，22，： | 1 |
| 13 | High-performance liquid chromatographic analysis of ampho-tericin B in rat plasma using α-naphthol as an internal standard显示文摘 | ITALIA J L SINGH D KUMAR M N V R | 2009 | Anal Chim Acta2009，634，1： | 1 |
| 14 | Phytoremediation: a novel strategy for the removal of toxic metals from the environment using plant 显示文摘 | SALT D E BLAYLOCK M KUMAR N | 1995 | Bio Technology1995，13，： | 1 |
| 15 | Acid catalyzed stere- oselective rearrangement and dimerization of flavenes : syn- thesis of dependensin 显示文摘 | Deodhar M Black D S Kumar N X | 2007 | Tetrahedron2007，63，24： | 1 |
| 16 | Polymerization in a reverse micelle nonreactor: Preparation of processable poly (p- phenylenevinylene) with controlled conjugation length 显示文摘 | LAL M KUMAR N D JOSHI M P | 1998 | Chemistry of Materials1998，10，4： | 1 |
| 17 | Enhancement of operational stability of an enzyme biosensor for glucose and sucrose using protein based stabilizing agents显示文摘 | Gouda M D Kumar M A Thakur M S | 2002 | Biosensors and Bioelectronics2002，，17： | 1 |
| 18 | A novel strategy for the removal of toxic metals from the environment using plants显示文摘 | Salt D E Blaylock M Kumar N | 1995 | Biotechnology1995，13，： | 1 |
| 19 | Apoptosis in isolated a- dult cardiomyocytes exposed to adriamycin 显示文摘 | Kumar D Kirshenbaum L Li T M | 1999 | Ann N Y Acad Sci1999，874，： | 1 |
| 20 | Pre- dicting outcome, in neonatal hypoxic respiratory fail- ure with the score for neonatal acute physiology (SNAP) and highest oxygen index (OI) in the first 24 hours of admission显示文摘 | KUMAR D SUPER D M FAJARDO R A | 2004 | J Perinatol2004，24，： | 1 |
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